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+Participants with clinical or radiographic evidence of pancreatitis are excluded
+Known history of acute or chronic pancreatitis
+Known history of acute or chronic pancreatitis
+History of acute pancreatitis within  year of study treatment or a history of chronic pancreatitis
+Recurrent or chronic pancreatitis
+History of acute pancreatitis within  year of study entry or history of chronic pancreatitis
+Patients with a prior history of documented pancreatitis are not eligible
+Predisposing characteristics for acute pancreatitis in the last month prior to randomization.
+History of chronic pancreatitis.
+Patients with laboratory evidence of pancreatitis are excluded.
+Patient has a history of pancreatitis
+History of recurrent pancreatitis
+History of acute pancreatitis within  year of study or history of chronic pancreatitis.
+History of acute pancreatitis within  year of study or history of chronic pancreatitis.
+Pancreatitis that is active or within the preceding  months which in the judgment of the endoscopist would make tumor injection likely to trigger severe recurrent pancreatitis
+History of pancreatitis
+Known active or chronic pancreatitis
+History of acute pancreatitis within one year of study or history of chronic pancreatitis
+Acute symptomatic pancreatitis within  months of study entry or a diagnosis of chronic pancreatitis at the time of randomization.
+History of acute pancreatitis within  year of study or history of chronic pancreatitis
+Known acute or chronic pancreatitis
+History of pancreatitis
+History of acute pancreatitis within  year of screening or past medical history of pancreatitis
+Known history of pancreatitis
+Known history of acute or chronic pancreatitis
+History of diverticulitis or pancreatitis within  weeks of registration
+Current pancreatitis
+Subject with history of acute within one year of study entry or past medical history of chronic pancreatitis
+History of pancreatitis
+No clinical or radiographic evidence of pancreatitis
+History of acute pancreatitis within  months prior to screening
+Acute or chronic pancreatitis
+Patient has a history of acute pancreatitis within  year of screening or a past medical history of chronic pancreatitis
+Subject has known acute or chronic pancreatitis.
+History of pancreatitis or chronic pancreatitis.
+Known symptomatic acute or chronic pancreatitis.
+The patient has a history of pancreatitis.
+Known history of acute or chronic pancreatitis
+Active or chronic pancreatitis
+No clinical evidence of pancreatitis
+History of acute pancreatitis within  year prior to registration, chronic pancreatitis, alcohol abuse or uncontrolled hypertriglyceridemia (triglycerides >  mg/dL)
+History of ? Grade  pancreatitis
+Has a history of acute or chronic pancreatitis
+PART B: History of acute pancreatitis within  year of study or history of chronic pancreatitis
+Diagnosis of acute or chronic pancreatitis
+Acute or chronic pancreatitis
+History of acute pancreatitis within  year prior to study entry or past medical history of chronic pancreatitis
+Individuals with a history of asparaginase-associated pancreatitis
+Patients with a prior history of documented pancreatitis
+Subjects with acute or chronic pancreatitis.
+Active or clinically symptomatic chronic pancreatitis or disease affecting pancreas
+Acute or chronic pancreatitis.
+History of acute or chronic pancreatitis
+History of pancreatitis of any grade
+History of pancreatitis
+History of acute or chronic pancreatitis or any risk factors that may increase the risk of pancreatitis.
+Known acute or chronic pancreatitis . Pregnant or lactating females Arm B only (CC- in combination with ibrutinib):
+History of acute pancreatitis within  year of study entry
+Acute or chronic pancreatitis
+Acute or chronic pancreatitis
+Recent history of acute pancreatitis.
+Recent ( months) history of acute pancreatitis.
+Known gallbladder or bile duct disease, acute or chronic pancreatitis
+Patients with recent history of pancreatitis
+History of acute pancreatitis within  year of study or history of chronic pancreatitis
+Known gallbladder or bile duct disease, symptomatic cholelithiasis, acute or chronic pancreatitis
+Indication for operative intervention being chronic pancreatitis
+Active or recent pancreatitis (within last  months)
+At least two episodes of acute pancreatitis in the past  months; acute pancreatitis is defined any  of the following: () typical upper abdominal pain; () elevation in serum amylase or lipase >=  times upper limit of normal; () features of acute pancreatitis on cross-sectional imaging
+Patients with a history of pancreatitis
+Known symptomatic acute or chronic pancreatitis.
+Acute or chronic pancreatitis
+Chronic or acute pancreatitis as evidenced by clinical or pathologic diagnosis
+History of acute pancreatitis within  year of study entry or past medical history of chronic pancreatitis