--- a +++ b/clusters/9knumclustersv2/clust_1563.txt @@ -0,0 +1,49 @@ +Severe liver dysfunction (Child-Pugh Class B or C) is not present; and +Child-Pugh class A +Patients with liver disease classified as Child Pugh class A or B, with score =< +Chronic liver disease, Child-Pugh class B or C +Impaired liver function Child-Pugh class B or C (score -). +Child-Pugh class B and C liver failure +Obtained with days of registration: Child Pugh class A (- points) or B ( points) +Child Pugh class B (,) and class C are excluded. +Child-Pugh class-A liver function +Child-Pugh class A or B liver function +Obtained =< days prior to registration: If baseline liver disease, Child Pugh score not exceeding class A +Child Pugh class B or greater hepatic dysfunction +Child Pugh class B & C +Several hepatic impairments, define as Child-Pugh Class C or worse +Child-Pugh class A or B without ascites +Child Pugh class C hepatic dysfunction +Child-Pugh Class A without either current encephalopathy or ascites. +Child-Pugh Class A +Cirrhotic status of Child-Pugh class A or B +Liver function status Child-Pugh (CP) Class A. CP status should be calculated based on clinical findings and laboratory results during the screening period. +Liver disease with Child-Pugh class B or C liver dysfunction +HCC patients only: Child Pugh class A or B liver disease +Subject is classified into Child-Pugh class C +Has a Child-Pugh Class A liver score within days of first dose of study drug. +Subject is classified into Child-Pugh class C +Child-Pugh Class A +Patients with hepatocellular carcinoma may be eligible provided they have total bilirubin ? . x ULN and are considered Child-Pugh Class A or Child-Pugh Class B (Child-Pugh Class B with a total Child-Pugh score not to exceed ). +Has a Child-Pugh Class A liver score within days of first dose of study drug +Preserved liver function (Child-Pugh class A or B) +Subject has hepatic function status of Child Pugh Class A at Screening. +Subject has status of Child-Pugh Class B or C at Screening. +Child-Pugh class A +Child-Pugh liver function class A +Systemic disease that would prevent study treatment (uncontrolled hypertension, cardiovascular renal, hepatic (including Child-Pugh Class B and C) or metabolic disease) +Child-Pugh Class A or B. +Subject has Child-Pugh score of less than (ie, class A or better) with neither encephalopathy nor clinically significant ascites (ascites requiring paracentesis within months of signing the ICF is excluded). Child-Pugh status is calculated based on clinical findings and laboratory results during the screening period. +Child Pugh Class A disease +Child-Pugh class A with no clinically apparent ascites +Child-Pugh class of A +Child-Pugh Class B and C. +Patients with impaired hepatic function as defined by Childs-Pugh class B or C +Child Pugh Class A liver function score +Must be Child-Pugh class A a. Patients with uncontrolled massive ascites or presence of hepatic encephalopathy are excluded +Child Pugh class A or B liver disease +Child-Pugh Class A. +Child-Pugh Class A in the absence of hepatoencephalopathy or clinically evident ascites +Child Pugh class A liver function or class B +Child-Pugh class B and C liver failure +Child-Pugh liver function Class B or C.