--- a +++ b/clusters/9knumclustersv2/clust_1551.txt @@ -0,0 +1,45 @@ +Histologically confirmed metastatic colorectal cancer, not amenable to curative resection +Histologically or cytologically confirmed GI malignancy for which mFOLFOX is considered an appropriate treatment (e.g., gastric cancer [GC], colorectal carcinoma, pancreatic adenocarcinoma) +Measurable, histologically/cytologically confirmed metastatic colorectal cancer (mCRC). +Pathologically documented diagnosis of colorectal adenocarcinoma. +Histologically confirmed unresectable metastatic colorectal adenocarcinoma +Histologically confirmed colorectal adenocarcinoma +Patients must have histologically or cytologically confirmed metastatic colorectal cancer. +Have histologically confirmed, locally advanced unresectable or metastatic (stage IV) colorectal adenocarcinoma +For patients with metastatic colorectal cancer:\r\n* Stage IV histologically-proven colorectal adenocarcinoma\r\n* Liver metastasis confirmed to be surgically resectable, with surgery evaluation and planned resection; may have minimal extrahepatic disease that is determined to be resectable\r\n* Tumor must be confirmed to be microsatellite stable (MSS); if not already reported at a Clinical Laboratory Improvement Act (CLIA)-certified laboratory, we will be able to perform this at Emory University\r\n* No prior immunotherapy\r\n* No cancer chemotherapy treatment weeks prior to day of treatment +Histologically confirmed diagnosis of colorectal adenocarcinoma +Patients must have histologically and or cytologically confirmed metastatic colorectal cancer +Participants must have histologically or cytologically confirmed adenocarcinoma of colorectal or pancreatic origin +Histologically confirmed colorectal cancer +Have a diagnosis of histologically confirmed metastatic colorectal cancer to the liver (no other sites of metastatic disease)\r\n* Histologic confirmation of a colorectal primary tumor is acceptable if accompanied by radiographic evidence of metastatic disease +Patients with histologically confirmed KRAS positive metastatic colorectal cancer +Histologically or cytologically confirmed metastatic colorectal adenocarcinoma (colon, rectal, colorectal, appendiceal cancer) or small bowel that is not resectable +Patients must have a histologically documented peritoneal carcinomatosis from either colorectal or appendiceal adenocarcinoma +Histologically or cytologically confirmed colorectal adenocarcinoma. +Histologically or cytologically confirmed colorectal adenocarcinoma +Histologically confirmed unresectable metastatic colorectal adenocarcinoma +Histologically or cytologically confirmed colorectal adenocarcinoma, with metastatic disease documented on diagnostic imaging studies +Histologically confirmed stage IV colorectal adenocarcinoma without any prior systemic treatment +Patients must have histologically or cytologically confirmed peritoneal surface malignancies from primary colorectal and appendiceal tumors +Locally confirmed dMMR or MSI-H stage IV colorectal carcinoma +Histologically confirmed recurrent or metastatic colorectal cancer +Histologically proven colorectal adenocarcinoma +Patients with histologically confirmed metastatic colorectal cancer, who have received and/or progressed on a prior oxaliplatin-based chemotherapy regimen +Histologically and/or cytologically confirmed and radiographically evaluable refractory metastatic colorectal adenocarcinoma for which regorafenib would be considered a therapeutic option +Cohort A: patients with histologically proven metastatic or locally advanced MSI colorectal adenocarcinoma +Cohort B: patients with histologically proven metastatic or locally advanced microsatellite stable (MSS) colorectal adenocarcinoma +A histologically or cytologically confirmed colorectal cancer that is metastatic, unresectable, or recurrent. +Patients must have histologically confirmed adenocarcinoma of colorectal origin that is metastatic or locally advanced and unresectable +History of histologically confirmed colorectal adenocarcinoma metastatic to the liver with no clinical or radiographic evidence of extrahepatic disease; confirmation of diagnosis must be performed by the enrolling institution +Histologically confirmed, chemo-refractory, locally advanced, recurrent or metastatic gastric (including GE junction), colorectal, or pancreatic adenocarcinoma. +Histologically or cytologically confirmed diagnosis of metastatic colorectal cancer with a product related mutation in Ras (GV, GC, GD, GR, QL, QR, QH) +Patients with histologically proven, unresectable, evaluable metastatic colorectal cancer, by RECIST criteria +Histologically confirmed colorectal cancer with at least one measurable metastatic lesion by RECIST v ., that is considered unresectable at baseline +Histologically confirmed colorectal cancer +Histologically or cytologically confirmed refractory colorectal cancer +Histologically or cytologically confirmed colorectal adenocarcinoma +Patients must have histologically confirmed, radiologically measurable metastatic or locally advanced unresectable colorectal adenocarcinoma that is amenable to image-guided biopsy; disease in previously radiated regions may not be considered measurable unless there has been demonstrated progression in the lesion +Histologically/cytologically proven colorectal carcinoma +Histologically confirmed peritoneal carcinomatosis from appendiceal, colorectal, ovarian, or primary mesothelioma, with no systemic metastases +Patients must have histologically or cytologically confirmed colorectal or pancreatic carcinoma +Histologically confirmed diagnosis of colorectal adenocarcinoma