Patients must have fully recovered from any adverse effects of major surgery (to =< grade ) at least days prior to registration Patient must have recovered from the surgery Recovered from any previous surgery and no history of major surgery within the last days prior to start of study drug Subject had major surgery within weeks prior to randomization (kyphoplasty is not considered major surgery); subjects should have been fully recovered from any surgical related toxicities. ? weeks since any major surgery and fully recovered. History or major surgery within weeks before the first dose of study treatment, or not recovered from prior surgery Has not fully recovered from any effects of major surgery without significant detectable infection. Prior major surgery within weeks or prior major surgery from which the patient has not sufficiently recovered yet PHASE II EXCLUSION CRITERIA: Prior major surgery within weeks or prior major surgery from which the patient has not sufficiently recovered yet Reasonably recovered from preceding major surgery as judged by the investigator or no major surgery within weeks prior to the start of Day treatment Not recovered from AEs and/or complications from major surgery prior to first dose Major thoracic or abdominal surgery from which the patient has not sufficiently recovered yet Fully recovered from any effects of major surgery, and be free of significant infection Reasonably recovered from preceding major surgery as judged by the investigator or no major surgery within weeks prior to the start of Day treatment Patients who have had major surgery must be fully recovered and >= weeks post-operative prior to enrolling on study Patients who have undergone major surgery within the weeks prior to starting study treatment or who have not fully recovered from previous surgery Major surgery must have been completed ? weeks prior to starting treatment day ; patient must be sufficiently recovered and stable from surgery prior to treatment day Major surgery within weeks prior to day of the study or who have not recovered from prior surgery Patients who have had major surgery must be fully recovered and require a recovery period of >= weeks prior to enrolling on study Reasonably recovered from preceding major surgery as judged by the Investigator or no major surgery within weeks prior to the start of Day treatment Major surgery within weeks prior to study day (subjects must have completely recovered from any previous surgery prior to study day ); biopsy, diagnostic tonsillectomy, airway tumor debulking or excisional lymph node biopsy do not constitute major surgery Major thoracic or abdominal surgery from which the patient has not sufficiently recovered yet Adequate recovery from all recent surgery is required. At least -days must have elapsed from the time of any major surgery, including craniotomy/tumor resection. Patients must have recovered from all surgery-related toxicities to Grade or less. Patients may not have had any prior tumor treatment except for surgery, and must have adequately recovered from surgery Patients who have undergone a major surgery, including surgery for a new artificial implant and/or device, within weeks prior to the initiation of ADXS- treatment; NOTE: All toxicities and/or complications must have recovered to baseline or grade\r\n prior to the initiation of ADXS- study therapy; sponsor must be consulted prior to enrolling subjects on the study who recently had a major surgery or have new artificial implant, and/or devices Patients may have received prior surgery provided that at least days have elapsed since major surgery (thoracic or other major surgeries) and the patient has recovered from all associated toxicities. Patients must have disease outside of the previous surgical resection area or a new lesion must be present. Patients must have recovered from the surgery Major surgery <= weeks before the first dose of study treatment. Subjects must have also fully recovered from any surgery (major or minor) and/or its complications before initiating study treatment. Major surgery (eg., requiring general anesthesia) within weeks before screening, or will not have fully recovered from surgery, or has surgery planned during the time the subject is expected to participate in the study At least weeks have elapsed since the completion of major surgery, and the patient has fully recovered from this surgery and any post-surgical complications Patient who has undergone major surgery =< weeks prior to starting study treatment or who has not recovered from side effects of such procedure; note: core needle biopsy, diagnostic tonsillectomy or excisional lymph node biopsy do not constitute major surgery Major surgery within weeks prior to day of the study or who have not recovered from prior surgery Patients must be at least weeks ( days) from major surgery and fully recovered from all acute effects of prior surgical intervention Major thoracic or abdominal surgery from which the patient has not yet recovered. Subjects must have recovered from surgery before study registration Patients may have received prior surgery (e.g., pleurectomy, pleurodeisis) provided at least days have elapsed since surgery (thoracic or other major surgeries) and patients have recovered from all associated toxicities at the time of registration; there must be no anticipated need for major surgical procedures during protocol treatment Patients may have received prior surgery; for all major surgeries, at least days must have elapsed since completion and patient must have recovered from all major side effects of surgery per investigators assessment Major surgery for any reason, except diagnostic biopsy, within weeks of enrolment and/or if the subject has not fully recovered from the surgery within weeks of enrolment PRIOR/CONCURRENT THERAPY CRITERIA: Patients must not have had a major surgery within days prior to registration; patients must have recovered from any adverse effects of prior surgery to the satisfaction of the treating physician; biopsies and central IV access placement are not considered major surgery Major surgery for any reason, except diagnostic biopsy, within weeks and/or if the subject has not fully recovered from the surgery within weeks Are at least weeks from major surgery and recovered. Plan for any major surgery during treatment period. Major surgery within weeks prior to Day of study or who have not recovered from prior surgery Patients must be at least weeks from major surgery and must be fully recovered Patients may have received prior surgery (e.g., pleurectomy) provided that at least days have elapsed since surgery (thoracic or other major surgeries) and patients have recovered (i.e., =< grade or at baseline) from all associated toxicities at the time of registration; there must be no anticipated need for major surgical procedures during protocol treatment Major thoracic or abdominal surgery from which the patient has not yet recovered. PART B: Patients who have had major surgery within days prior to entering the study or those who have not recovered from adverse events > grade relating to the surgery Fully recovered from any prior surgery and/or radiation and none within weeks of initiating treatment Patients who have not recovered from prior surgery Major surgery within weeks prior to day of study treatment from which the patient has not completely recovered Patients having undergone major surgery less than weeks prior to enrollment or have not fully recovered from prior surgery Major surgery within weeks prior to day of the study or who have not recovered from prior surgery Patient has undergone a major surgery, including surgery for a new artificial implant and/or device, within weeks prior to the initiation of ADXS- treatment; NOTE: all toxicities and/or complications must have recovered to baseline or grade prior to the initiation of ADXS- study therapy; sponsor must be consulted prior to enrolling patients on the study who recently had a major surgery or have new artificial implant, and/or devices Major surgery within three months prior to Day of study or who have not recovered adequately from prior surgery. Patients who have had major surgery must be fully recovered and >= weeks post-operative prior to enrolling on study Major surgery within weeks prior to day of the study or who have not recovered from prior surgery Major surgery within weeks prior to Baseline. The subject must have recovered from surgery and be without current complications of infection or dehiscence. At least weeks have elapsed since the completion of major surgery, and the patient has fully recovered from this surgery and any post-surgical complications. Patients must be at least weeks from major surgery and have fully recovered from any effects of surgery, and be free of significant detectable infection prior to registration Plan for any major surgery during treatment period. Prior major surgery from which the subject has not yet recovered to baseline; Be reasonably recovered from preceding major surgery as judged by the investigator or no major surgery within weeks prior to the start of day treatment Patients must have fully recovered from any effects of major surgery, and be free of significant detectable infection Fully recovered from any prior surgery and no major surgery within weeks of initiating treatment, except for gamma knife which can take place within weeks. Surgery for placement of vascular access devices is acceptable. Patients must be at least weeks from major surgery and have fully recovered from any effects of surgery, and be free of significant detectable infection If a patient has had major surgery, the patient must be longer than four weeks post surgery and must have recovered from all toxicity prior to beginning protocol study Major surgery/surgical therapy for any cause within month prior to pasireotide administration; patients should have recovered and have a good clinical condition before entering the study Have reasonably recovered from preceding major surgery as judged by the investigator or have had no major surgery within weeks prior to Day treatment. Patient is planning major surgery within the next months >= weeks since last major surgery and fully recovered Patients must have recovered from prior surgery Recovered from major surgery within the last months The patient must be recovered from a prior major surgery; the major surgery must be performed at least weeks prior to consent date Participants with acute intercurrent illness or those who had major surgery within the preceding weeks unless they have fully recovered Participants with acute intercurrent illness or those who had surgery within the preceding weeks unless they have fully recovered Patients may have received prior radiation therapy or major surgery; however, at least days prior to treatment start must have elapsed since completion of radiation therapy or major surgery and patient must have recovered from all side effects at the time of randomization recovered from any prior surgery