--- a +++ b/clusters/9knumclustersv2/clust_1492.txt @@ -0,0 +1,24 @@ +Documented LVEF of less than or equal to % tested in patients with:\r\n* Clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block or have a history of ischemic heart disease, chest pain\r\n* Age >= years old +Documented LVEF of less than or equal to %, note: testing is required in patients with:\r\n* Age >= years old\r\n* Clinically significant atrial and or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block, or history of ischemic heart disease or chest pain +Documented left ventricular ejection fraction (LVEF) of less than or equal to % tested in patients with:\r\n* Clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block, chest pain, or ischemic heart disease\r\n* Age >= years old +Documented LVEF of less than or equal to % tested in patients with:\r\n* Clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block or have a history of ischemic heart disease, chest pain\r\n* Age >= years old +Documented left ventricular ejection fraction (LVEF) =< % tested in patients:\r\n* Age >= years\r\n* With clinically significant atrial and/or ventricular arrhythmias, including but not limited to: atrial fibrillation, ventricular tachycardia, second- or third-degree heart block, or have a history of ischemic heart disease and/or chest pain. +Documented LVEF =< % tested in patients with:\r\n* Age >= years\r\n* With clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second- or third-degree heart block or have a history of ischemic heart disease and/or chest pain +Documented left ventricular ejection fraction (LVEF) of less than or equal to %; testing is required in patients with:\r\n* Clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block or have a history of ischemic heart disease or chest pain\r\n* Age >= years old +Documented left ventricular ejection fraction (LVEF) of less than or equal to % tested; the following patients will undergo cardiac evaluations:\r\n* Clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block or\r\n* Age >= years old +Documented left ventricular ejection fraction (LVEF) of less than or equal to %; testing is required in patients with:\r\n* Clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block or have a history of ischemic heart disease, or chest pain\r\n* Age >= years old\r\n* Prior treatment with significant exposure to anthracyclines or cyclophosphamide +Documented left ventricular ejection fraction (LVEF) of less than or equal to %; testing is required in patients with:\r\n* Clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block\r\n* Age >= years old +Documented left ventricular ejection fraction (LVEF) of less than or equal to %; note: testing is required in patients with:\r\n* Age >= years old\r\n* Clinically significant atrial and or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block or have a history of ischemic heart disease, chest pain +Documented left ventricular ejection fraction (LVEF) of less than or equal to %; testing is required in patients who are:\r\n* Age >= years old\r\n* Clinically significant atrial and or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block or have a history of ischemic heart disease, or chest pain +Documented left ventricular ejection fraction (LVEF) of less than or equal to % testing is required in patients who are\r\n* >= years old\r\n* Clinically significant atrial and or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block or have a history of ischemic heart disease, or chest pain +Documented left ventricular ejection fraction (LVEF) of less than or equal to %; testing is required in patients with:\r\n* Clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block, chest pain, or ischemic heart disease\r\n* Age >= years old +Documented LVEF =< % tested in patients:\r\n* Age >= years\r\n* With clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second-or third-degree heart block or have a history of ischemic heart disease and/or chest pain +Documented left ventricular ejection fraction (LVEF) of less than or equal to %; note: testing is required in patients with:\r\n* Age >= years old\r\n* Clinically significant atrial and or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block or have a history of ischemic heart disease, chest pain +The following patients will be excluded from the high-dose aldesleukin arm (but may be eligible for cells alone arm):\r\n* History of coronary revascularization or ischemic symptoms\r\n* Documented left ventricular ejection fraction (LVEF) of less than or equal to %; testing is required in patients with:\r\n** Clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block\r\n** Age >= years' old\r\n* Clinically significant patient history which in the judgment of the principal investigator would compromise the patients ability to tolerate aldesleukin +Documented left ventricular ejection fraction (LVEF) of less than or equal to %, testing is required in patients with:\r\n* Clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block\r\n* Age >= years old +Documented left ventricular ejection fraction (LVEF) of less than or equal to %; testing is required in patients with:\r\n* Clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block\r\n* Age >= years old +Documented left ventricular ejection fraction (LVEF) of less than % tested in patients with:\r\n* History of ischemic heart disease, chest pain, or clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block\r\n* Age greater than or equal to years old +Documented left ventricular ejection fraction (LVEF) of less than or equal to % tested; the following patients will undergo cardiac evaluations\r\n* Clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block or\r\n* Age >= years old +Documented LVEF of less than or equal to % tested in patients with i) clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block or ii) age >= years old +Documented left ventricular ejection fraction (LVEF) of less than or equal to %, testing is required in patients with:\r\n* Age >= years old\r\n* Clinically significant atrial and or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block +Documented left ventricular ejection fraction (LVEF) of less than or equal to %; testing is required in patients with:\r\n* Clinically significant atrial and/or ventricular arrhythmias including but not limited to: atrial fibrillation, ventricular tachycardia, second or third degree heart block\r\n* Age >= years old