With otolaryngeal cancer receiving surgery with general anesthesia\r\n* Please note we are purposefully including patients with higher predisposition to delirium as we are investigating potential preventive strategies for this diagnosis of multiple etiologies; patients at higher risk of delirium (e.g., advanced age, chronic hypertension) will be included in our study; additionally, other common risk factors that exist in this patient population (e.g., alcohol or nicotine use) are thought to contribute to delirium postoperatively
Part : patients will be excluded if () have clinical evidence of cognitive failure as evidenced by Memorial Delirium Assessment Scale score of ?  at baseline
Delirium (i.e., score > on the Memorial Delirium Assessment Scale; range -).
Delirium (i.e. Memorial Delirium Rating Scale > )
PATIENTS: Hyperactive or mixed delirium with RASS >=  in the past  hours (h)
Memorial Delirium Rating Scale > 
Delirium (i.e., Memorial Delirium Rating Scale > )
Delirium (i.e. memorial delirium rating scale > )
Cognitive impairment with a Memorial Delirium Assessment Scale (MDAS) score of  or higher or diagnosed with neurocognitive impairment by the treating SCC physician
Presence of relatively intact cognition defined by normal memorial delirium assessment scale (< /); sign written informed consent
Memorial Delirium Assessment Scale > /
Patients must have no clinical evidence of cognitive impairment as determined by the palliative care physician (Memorial Delirium Assessment Score >= )
Hyperactive/mixed delirium with RASS >=  in the last  hours
At the patients bedside at least  hours each day during patient delirium episode
Delirium (i.e. memorial delirium rating scale > )
Delirium (i.e. Memorial delirium rating scale > )
Delirium (i.e. memorial delirium rating scale > )
Memorial delirium assessment scale =< 
Have no clinical evidence of cognitive failure as evidenced by Memorial Delirium Assessment Scale (MDAS) score of =<  at baseline
Memorial delirium assessment scale =< 
Altered cognition (as assessed routinely in the Supportive Care Clinic using the Memorial Delirium Assessment Scale [MDAS], with a score of >= /)
Patients with normal cognitive status (Memorial Delirium Assessment Scale [MDAS] =< /) who are able to understand the nature and purpose of the study and have the ability to complete the consent process