--- a +++ b/clusters/9knumclustersv2/clust_147.txt @@ -0,0 +1,70 @@ +ALT ? . x ULN f. Estimated glomerular filtration rate of at least mL/min by the Cockcroft Gault formula +Glomerular filtration rate (GFR) >= mL/min estimated by Cockcroft-Gault or measured directly by hour urine creatinine within days prior to Step registration +Serum creatinine (Scr) =< .mg/dl; if the Scr > ., patients may still be eligible if the calculated glomerular filtration rate (GFR) (Cockroft-Gault) is >= ml/minute +End-stage renal disease (estimated glomerular filtration rate [GFR] < ml/min/body surface area [BSA]), unless the estimated creatinine clearance by Cockcroft Gault is >= ml/min prior to randomization +Serum creatinine ? . X ULN OR calculated glomerular filtration rate (GFR) by Cockcroft-Gault formula ? mL/min +Creatinine clearance ? mL/min on the basis of the Cockcroft-Gault glomerular filtration rate calculation +Glomerular filtration rate (GFR) greater than or equal to ml/min using the Cockcroft-Gault formula or serum creatinine less than or equal to . x upper limit of normal (ULN) +Serum creatinine within normal range, or if serum creatinine outside normal range, then glomerular filtration rate (GFR) > mL/min/.m as calculated with the Cockcroft-Gault equation with adjustment if total body weight is ? % of ideal body weight. +Renal: For patients > . years of age at the time of enrollment: estimated creatinine clearance > mL/minute (using the Cockcroft-Gault formula and actual body weight). For patients < . years of age at enrollment: Glomerular Filtration Rate (GFR) estimated by the updated Schwartz formula ? mL/min/. m. If the estimated GFR is < mL/min/. m^, then renal function must be measured by -hour creatinine clearance or nuclear GFR, and must be > mL/min/. m^. +Estimated glomerular filtration rate (GFR by Cockroft-Gault equation OR hour urine collection >= ml/min +Serum creatinine: < . mg/dL or calculated glomerular filtration rate (GFR) >= cc/min; creatinine clearance (CrCl) by Cockcroft Gault will be used to estimate GFR +Creatinine < . x ULN or estimated Glomerular Filtration Rate GFR [Cockcroft-Gault] > mL/min +Glomerular filtration rate (GFR), calculated via I- iothalamate clearance, -hour creatinine clearance, or Schwartz formula, >= mL/min or >= mL/min/. m^ done within weeks prior to study entry +Pediatric population (patients < years): creatinine within normal limits or calculated creatinine clearance >= ml/min/. m^ as calculated by the Schwartz formula for estimated glomerular filtration rate (GFR) +Serum creatinine < . ULN OR an estimated glomerular filtration rate ? mL/minute using the Cockroft-Gault formula. +Creatinine clearance or glomerular filtration rate >= ml/min/. m^ (calculated or measured as appropriate for age and level of concern by treating medical doctor [MD]) +Glomerular filtration rate (GFR) greater than or equal to ml/min using the Cockcroft-Gault formula or serum creatinine less than or equal to . x ULN +Glomerular filtration rate (GFR) greater than or equal to ml/min using the Cockcroft-Gault formula or serum creatinine less than or equal to . x upper limit of normal (ULN) +Creatinine < . x ULN or estimated glomerular filtration rate (GFR) >= ml/min by Cockcroft-Gault +Estimated GFR >mL/min/.m +A serum creatinine based on age/gender, derived from the Schwartz formula for estimating glomerular filtration rate (GFR), per protocol-specified criteria. +Ineligible for cisplatin as defined by presence of one or more of the following:\r\n* Impaired renal function (glomerular filtration rate [GFR] >= but =< cc/min); GFR should be assessed by direct measurement (i.e. creatinine clearance or ethylenediaminetetra-acetate) or, if not available, by calculation from serum/plasma creatinine by Cockroft-Gault equation\r\n* Grade >= hearing loss (measured by loss of > dB at two contiguous frequencies in at least one ear)\r\n* Grade >= peripheral neuropathy\r\n* ECOG performance status of \r\n* Solitary kidney +Estimated creatinine clearance >= mL/min ( hour measured glomerular filtration rate [GFR] or modified Cockcroft Gault) +Glomerular filtration rate (GFR) < mL/min, as assessed using the standard methodology at the investigating center (i.e. Cockroft-Gault), or serum creatinine > . x ULN +For patients >= . year of age but < . years of age at the time of enrollment: glomerular filtration rate (GFR) estimated by the updated Schwartz formula >= mL/min/. m^; if the estimated GFR is < mL/min/. m^, then renal function must be measured by -hour creatinine clearance or nuclear GFR, and must be > mL/min/. m^ +Estimated GFR < ml/min +Kidney: estimated glomerular filtration rate (Cockcroft-Gault) ? mL/min. +Within months of registration: Glomerular filtration rate (GFR) >= mL/min; Cockcroft-Gault formula will be used to calculate creatinine clearance +A serum creatinine based on age/gender, derived from the Schwartz formula for estimating glomerular filtration rate (GFR) +Within days of first dose of study drug: Serum creatinine =< . x ULN or estimated glomerular filtration rate (GFR) >= mL/min using the Cockcroft Gault formula +Estimated creatinine clearance of >= ml/min according to the Cockcroft-Gault formula, unless calculated to be < ml/min or borderline in which case glomerular filtration rate (GFR) should be formally measured, e.g. with edetic acid (EDTA) scan +Glomerular filtration rate ? ml/min based on Cockcroft-Gault equation +Patients must not be suitable for concurrent cisplatin as determined by the following:\r\n* Creatinine clearance less than ml/min; glomerular filtration rate (GFR) should be assessed by calculation from serum/plasma creatinine (Cockcroft-Gault formula)\r\n* Common Terminology Criteria for Adverse Events (CTCAE) grade (Gr) >= hearing loss\r\n* CTCAE Gr >= neuropathy +Serum creatinine =< . x ULN or estimated glomerular filtration rate (GFR) >= mL/min using Cockcroft Gault formula +Creatinine within institutional normal limits or Glomerular filtration rate (GFR) > mL/min/m^ (calculated by the Cockcroft-Gault equation), calculated as follows:\r\n* For males = (( age[years]) x (body weight [kg]))/(() x (serum creatinine [mg/dL]))\r\n* For females = . x male value +Creatinine within institutional normal limits or glomerular filtration rate (GFR) > mL/min/m^ (calculated by the Cockcroft-Gault equation) +Adequate renal function: Estimated glomerular filtration rate ? mL/minute using the Cockroft-Gault formula or: a serum creatinine based on age/gender as outlined in the protocol +Estimated glomerular filtration rate (GFR) ? mL/min as assessed by CKD-epi, MDRD or the Cockcroft-Gault Equation +Glomerular filtration rate (GFR) greater than or equal to ml/min using the Cockcroft-Gault formula or serum creatinine less than or equal to . x upper limit of normal (ULN) +Creatinine clearance estimated glomerular filtration rate (GFR) >= mL/min/. m^ (Cockcroft-Gault) +Creatinine < mg/dl; glomerular filtration rate (GFR) > mL/min (Cockroft and Gault formula) +Serum creatinine =< . x ULN or -hour clearance >= mL/min or calculated glomerular filtration rate (GFR) of cc/ml using the formula of Cockcroft and Gault +Serum creatinine =< . mg/dL or estimated glomerular filtration rate (GFR) (by Cockcroft-Gault) >= mL/min or or hour urine creatinine clearance >= mL/min, unless renal insufficiency is due to tumoral ureteral obstruction in which case eligibility will be determined by the national principal investigator (or national co-PI or MSKCC co-PI if the national PI is unavailable) with notification of the MSKCC Institutional Review Board (IRB) +Serum creatinine ?.upper limit of normal (ULN), or glomerular filtration rate > mL/min, as calculated with the Cockcroft-Gault formula. +Creatinine clearance estimated (est.) glomerular filtration rate (GFR) >= mL/min/. m^ (Cockcroft-Gault) +Glomerular filtration rate (GFR) > mL/min (by standard Cockcroft and Gault formula or measured via hour urine collection) +Renal: serum creatinine (SCr) within normal range for age (see table .). If SCr is outside normal range for age, creatinine clearance (CrCl) > mL/min/.m must be obtained (measured by -hour (hr) urine specimen or nuclear glomerular filtration rate (GFR), or calculated GFR (by Cockcroft-Gault formula for those aged ? years; by Original Schwartz estimate for those < years)) +Adequate renal function with estimated glomerular filtration rate (GFR) by Cockcroft Gault of greater than ML per minute +The standard Cockcroft and Gault formula or the measured glomerular filtration rate must be used to calculate creatinine clearance (CrCl) for enrollment or dosing +Calculated creatinine clearance >= mL/min (Cockcroft-Gault formula) or serum creatinine (Cr) less than institution ULN (the elderly will often have < glomerular filtration rate [GFR]) +Glomerular filtration rate (GFR) > mL/minute as calculated by the Cockcroft-Gault formula +Creatinine < . x ULN or creatinine clearance (estimated [est.] glomerular filtration rate [GFR] [Cockcroft-Gault]) >= mL/min +Serum creatinine =< . x ULN or glomerular filtration rate (GFR) of cc/ml using the formula of Cockcroft and Gault +Serum creatinine ? . x upper limit of normal (ULN) or an estimated glomerular filtration rate (eGFR) of > mL/min as calculated by the Cockcroft Gault Method +Serum creatinine <. x upper limit of normal (ULN) or estimated glomerular filtration rate of > mL/min as calculated by the Cockcroft Gault Method +Estimated GFR > mL/min/. m^ +Creatinine clearance (Cockcroft-Gault) greater than or equal to mL/min or estimated (est) glomerular filtration rate (GFR) greater than or equal to mL/min/. m^ +Calculated creatinine clearance (CRCL) ? mL/min. Glomerular Filtration Rate (GFR) is calculated based on Cockcroft-Gault method. +Calculated creatinine clearance > ml/min/.m^ as calculated by the Schwartz formula for estimated glomerular filtration rate +Serum creatinine ? . x ULN; or if serum creatinine > . ULN, then calculated (Cockcroft-Gault formula, glomerular filtration rate (GFR) ? mL/min; +Pediatric Population (age <): Calculated creatinine clearance ? ml/min/.m as calculated by the Schwartz formula for estimated glomerular filtration rate (GFR) +Estimated (calculated) or measured glomerular filtration rate >= mL/min (or mL/min/. m^); creatinine (mg/dl) used in calculation (Cockroft-Gault) must be obtained within days prior to registration +CROSSOVER (STEP ) REGISTRATION: Estimated (calculated) or measured glomerular filtration rate >= mL/min (or mL/min/. m^) within days prior to registration; creatinine (mg/dl) used in calculation (Cockroft-Gault) must be obtained within days prior to registration +Glomerular filtration rate >= mL/min (calculated according to the formula of Cockcroft and Gault) +Does the subject have an estimated glomerular filtration rate of at least mL/min (inclusive) by the Cockcroft-Gault formula? +Glomerular filtration rate (GFR) > mL/min/.m^ according to the Cockcroft-Gault estimation. +Glomerular filtration rate (GFR) >= ml/minute using Cockroft-Gault formula +Subjects with severe renal failure or end stage renal disease (estimated GFR [glomerular filtration rate] of < mL/min) as estimated by the Cockcroft-Gault formula +Estimated creatinine clearance (for patients > years) greater than . mL/minute (using the Cockcroft-Gault formula and actual body weight); for pediatric patients (> year to years), Glomerular Filtration Rate (GFR) estimated by the updated Schwartz formula ? . mL/min/. m^. If the estimated creatinine clearance is < mL/min/. m^, then renal function must be measured by -hour creatinine clearance or nuclear GFR, and must be > . mL/min/. m^. +Estimated glomerular filtration rate (GFR) (using Cockcroft formula) less than ml/min/. m^