--- a +++ b/clusters/9knumclustersv2/clust_1467.txt @@ -0,0 +1,13 @@ +Has taken valproic acid, or another histone deacetylase inhibitor, within weeks prior to study day +Patients taking any histone deacetylase inhibitor (HDACi) other than vorinostat +Patients should not have taken valproic acid or another histone deacetylase inhibitor for at least weeks prior to enrollment +Previous treatment with an histone deacetylase inhibitor or an epidermal growth factor receptor inhibitor within at least weeks of the date of first administration of study drug +Prior treatment with a histone deacetylase inhibitor +Participants should not have taken valproic acid or another histone deacetylase inhibitor for at least weeks prior to study enrollment +Patients should not have taken valproic acid or another histone deacetylase inhibitor for at least weeks prior to enrollment +CTCL disease that is known to be refractory to systemic histone deacetylase inhibitors +Received immunomodulating agents, histone deacetylase inhibitors, cyclosporine, or mycophenolate within weeks of screening +Patients may not have taken another histone deacetylase inhibitor (i.e. valproic acid, vorinostat) for at least weeks prior to enrollment +Patients should not have taken valproic acid, another histone deacetylase (HDAC) inhibitor, for at least weeks prior to enrollment +Previous therapy with histone deacetylase inhibitor. +For subjects assigned to take vorinostat, prior exposure to vorinostat or other known histone deacetylase (HDAC) inhibitors for cancer therapy; patients should not have taken valproic acid, another histone deacetylase inhibitor, for at least weeks prior to study enrollment; note: this criterion does NOT apply to subjects treated on the Expansion Cohort (accruals post February , )