--- a +++ b/clusters/9knumclustersv2/clust_1452.txt @@ -0,0 +1,35 @@ +Serum creatinine level =< IULN within days prior to registration +Within days prior to registration: Serum creatinine =< . x IULN +Patients must have adequate renal function with serum creatinine level =< IULN within days prior to registration +Serum creatinine =< . x IULN within days prior to registration +Patients must have creatinine clearance =< . x IULN +Patients must have serum creatinine =< x institutional upper limits of normal (IULN) within days prior to registration +Serum creatinine =< . x the IULN +Creatinine =< . x IULN OR creatinine clearance >= mL/min/. m^ for patients with creatinine levels > . x IULN (that is, if serum creatinine is > . x IULN, a -hour urine collection to calculate creatinine clearance must be performed) +Serum creatinine =< . x institutional upper limit of normal (IULN) OR creatinine clearance by Cockcroft-Gault >= mL/min for patients with serum creatinine > . x IULN +Serum creatinine =< . x IULN OR creatinine clearance by Cockcroft-Gault >= mL/min/. m^ for patients with creatinine levels > . x IULN +Adequate renal and hepatic function (creatinine ? . x IULN, bilirubin ? . IULN, AST and ALT ? . x IULN or x IULN if known liver metastases). +Serum creatinine =< . x IULN OR creatinine clearance by Cockcroft-Gault >= mL/min/. m^ for patients with creatinine levels > . x IULN +Serum creatinine =< . x IULN OR creatinine clearance by Cockcroft-Gault >= mL/min/. m^ for patients with creatinine levels > . x IULN +Serum creatinine < x IULN +Adequate renal and hepatic function (creatinine ? . x IULN, bilirubin ? IULN, AST and ALT ? . x IULN or x IULN if know liver metastases). +Creatinine =< . x IULN OR measured or calculated creatinine clearance >= mL/min for patients with creatinine levels > . x IULN +Adequate renal and hepatic function (creatinine ? . x IULN, bilirubin within normal limits, AST and ALT ? . x IULN or x IULN if know liver metastases) +Creatinine =< . x IULN +Within days of subject registration: Serum creatinine =< . X IULN +Baseline BNP > x IULN +Serum creatinine =< . x IULN +Serum creatinine =< x institutional upper limit of normal (IULN), unless due to lymphoma, within day prior to registration +Performed within days of patient registration: Serum creatinine =< . x IULN +Serum creatinine =< IULN within days prior to registration +Serum creatinine =< . x IULN within days prior to Step Randomization OR +Serum creatinine =< . x IULN within days prior to Step registration OR +Patients must have adequate organ and bone marrow function prior to registration, as defined below: \r\n* Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) < x institutional upper limit of normal (IULN)\r\n* Total bilirubin < . x IULN (unless Gilbert syndrome has been diagnosed); if leukemia infiltration of the liver is suspected to be causing liver function abnormalities the patient will still be eligible with principal investigator (PI) approval\r\n* Creatinine < x IULN\r\n* Creatinine clearance > mL/min (measured by Cockroft-Gault) +Baseline troponin I or T > IULN and b-type natriuretic peptide > IULN +Serum creatinine level =< IULN +Serum creatinine =< . x IULN (assessed within days prior to study day ) +Serum creatinine =< . x IULN OR creatinine clearance by Cockcroft-Gault >= mL/min/. m^ for patients with creatinine levels > . x IULN +Serum creatinine < . x IULN within days prior to registration +Serum creatinine =< . x IULN +Serum creatinine =< . x IULN obtained within days prior to registration +Adequate baseline hematological and organ function, assessed by laboratory values prior to study treatment as follows: absolute neutrophil count (ANC) > . x /L; hemoglobin > g/dL; serum creatinine < x institutional upper limit of normal (IULN); aspartate transaminase (AST) < . x IULN; alanine transaminase (ALT) < . x IULN; (if liver metastases are present, ALT and AST < x IULN); total bilirubin < . x IULN.