--- a
+++ b/clusters/9knumclustersv2/clust_137.txt
@@ -0,0 +1,20 @@
+Documented progression on and/or intolerance/hypersensitivity to both paclitaxel and irinotecan (Part B only)
+Known hypersensitivity or intolerance to metformin
+Known hypersensitivity/intolerance to capecitabine, infusional -flurouracil, or bevacizumab
+Known or suspected intolerance or hypersensitivity to IT- or any of the stated ingredients.
+Known hypersensitivity or intolerance to metformin
+Known hypersensitivity or intolerance to any of the agents under investigation
+Known hypersensitivity or intolerance to any of the agents under investigation
+History of intolerance or hypersensitivity to study drug
+Intolerance or hypersensitivity to octreotide
+Have a history of hypersensitivity to any study drugs or their excipients, or intolerance to hydration due to preexisting pulmonary or cardiac impairment, or intolerance to opioid pain medications, or a history of severe hypersensitivity to any other antigen.
+Known hypersensitivity or intolerance to dexamethasone
+Patients with known hypersensitivity or intolerance to melphalan
+Known hypersensitivity or intolerance to metformin
+Known intolerance of or hypersensitivity to fosbretabulin
+History of hypersensitivity or severe intolerance to azoles
+Known hypersensitivity or intolerance to metformin
+No known hypersensitivity or intolerance to metformin
+Known intolerance, hypersensitivity, or contraindication to glucocorticoids.
+Subject has intolerance or hypersensitivity to iron or dextran compounds or to SiennaXP.
+Known hypersensitivity or intolerance to itraconazole or similar class agents.