--- a +++ b/clusters/9knumclustersv2/clust_1327.txt @@ -0,0 +1,184 @@ +Life expectancy of at least months from most recent chemotherapy or immunotherapy treatment +No comorbid conditions that would cause life expectancy of less than years +Patients must have a life expectancy of >= weeks as determined clinically by the treating physician +Life expectancy of at least weeks based on investigator estimate +Have ECOG PS of or with an anticipated life expectancy of > months. +Life expectancy < years +Life expectancy of > months as defined by agreement of both the Chow et al. and TEACHH models +SAFETY RUN-IN: Life expectancy of less than months +Subject must have a life expectancy >= years +PIKCA WILD TYPE COHORT (closed //): Life expectancy > months +Patients with life expectancy >= weeks from time of CTL infusion +Life expectancy of at least months in the judgment of the physician +No prior primary or metastatic brain or meningeal tumors unless clinically and radiographically stable as well as off steroid therapy for at least months; a. Life expectancy ? weeks all (US); b. Life expectancy ? weeks; ? weeks superficial tumors (Canada); +Patients with short life expectancy (less than months) due to comorbidity other than MDS or CMML +Life expectancy ? mos +Life expectancy ? years, as judged by the site investigator +Life expectancy of less than months in the judgment of the study physician. +Patients with a life expectancy < months from co-existing disease other than the leukemia or RAEB +Life expectancy >= days +Must have a life expectancy of at least years based on age and comorbidities but excluding diagnosis of breast cancer. +Patients with a life expectancy of less than years +No active or co-existing malignancy with life expectancy less than months +No active or co-existing malignancy with life expectancy less than months +Life expectancy >= weeks as judged by the treating physician. +Life expectancy >= days +Co-existing medical conditions with life expectancy < years +Patients with a life expectancy of < months of enrollment from coexisting disease other than leukemia +Life expectancy less than years; +Patients must have life-expectancies > months to be included in the trial +Life expectancy of at least years +Life expectancy >= months at the time of study drug administration +Minimum life expectancy of at least weeks. Expanded Safety Phase: +Patients with any severe concomitant disease that may limit their life expectancy to less than years +Life expectancy of ? months from the first OBP- treatment. +Life expectancy < months (as estimated per diagnosis-specific graded prognostic assessment [ds-GPA]) +Life expectancy of over months as determined by treating physician +Life expectancy less than years +Patients with short life expectancy (less than months) due to comorbidity other than MDS +Life expectancy of >= weeks based on investigator estimate +ECOG Grade - , with minimum life expectancy of at least months; +Patients with life expectancy of =< months for reasons other than their underlying hematologic/oncologic disorder +Presence of other comorbid illnesses with an estimated median life expectancy < years +Subject has an ECOG Performance Status - and anticipated life expectancy > months prior to apheresis and > months prior to lymphodepletion. +Life expectancy of greater than months (does not apply to pancreatic cancer population) +Have at least month life expectancy +Subjects must have a reasonable life expectancy of at least months +Life expectancy =< months in the judgment of the treating clinician +Life expectancy > weeks as judged by investigators +Life expectancy of >= weeks (per treating investigators discretion) +Life expectancy >= years (as determined by the treating physician) +CAPMATINIB INCLUSION CRITERIA: Life expectancy >= weeks +CERITINIB INCLUSION CRITERIA: Life expectancy >= weeks +Patients with life expectancy of =< months for reasons other than their underlying hematologic/oncologic disorder +No active or co-existing malignancy with life expectancy less than months +Life expectancy >= weeks excluding their diagnosis of breast cancer +Life expectancy with treatment should be >= months in the estimation of the treating physicians +A life expectancy of at least weeks, even if requiring artificial ventilation. +Life expectancy of at least years +Life expectancy of >= years (yrs) +Other serious medical conditions that may be expected to limit life expectancy to less than years (e.g., liver cirrhosis). +At least month life expectancy +Life expectancy > years +Must have a life expectancy of at least years based on age and co-morbidities. +Patients with life expectancy of =< months for reasons other than their underlying hematologic/oncologic disorder +Life expectancy of greater than months to allow completion of study treatment and assessment of dose-limiting toxicity +Patients with life expectancy of =< months for reasons other than their underlying hematologic/oncologic disorder +A life expectancy of at least months with a Karnofsky performance status of at least +Patients with life expectancy of =< months for reasons other than their underlying hematologic/oncologic disorder +Minimum life expectancy of six weeks as determined by consenting professional +No life expectancy restrictions will apply +Life expectancy of >= years as determined by treating physician +Patients with co-existing medical conditions with life expectancy < years +Life expectancy reasonably adequate for evaluating the treatment effect +A serious underlying medical condition other than NSCLC such that life expectancy is less than years. +INCLUSION CRITERIA FOR CCT: minimum life expectancy of eight weeks +life expectancy of less than months; Related to anticoagulant treatment: +Life expectancy of at least days +Stable clinical conditions and life expectancy > months +Other life-threatening illness that is expected to impact life expectancy within years +The patient has a prior or concurrent malignancy that in the opinion of the investigator, presents a greater risk to the patients health and survival, than of the MCL with a life expectancy < years. +Life expectancy of >= months in the attending physicians estimation +Life expectancy estimate > months +Life expectancy of > years per the clinical impression of the treating physician(s) +Life expectancy > months as assessed by study physician +TUMOR BIOPSY SEQUENCING: Life expectancy > months +Life expectancy of >= years +Minimum expected life expectancy > months +< years life expectancy +Life expectancy < years +Life expectancy of at least months based on Investigators judgment. +Life expectancy ? years +Life expectancy of at least years, disregarding the diagnosis of cancer; +ECOG Performance Status - and anticipated life expectancy > months. +Patients with other active malignancies (no evidence of other cancer or life expectancy greater than years) are ineligible for this study +Life expectancy ? years. +Life expectancy >= months at the time of study drug administration +Diagnosis of a coexisting medical condition which limits life expectancy to < years +Life expectancy of at least years +Life expectancy < days. +Have ECOG PS of or with an anticipated life expectancy of > months. +Patients must have an anticipated life expectancy > months. +Patients must have a life expectancy of >= days +Life expectancy < months as assessed by the treating physician +Patient ? years of age. Patient life expectancy > months. Eastern cooperative group (ECOG) of or +Life expectancy > years +Life expectancy of at least years from the time of diagnosis, not considering the melanoma in question, as determined by the PI. +Life expectancy of < months and/or has rapidly progressing disease +Subject must be ? years of age. Life expectancy > weeks. +Patients must have a life expectancy >= days +Life expectancy >= months as determined by the treating physician +Life expectancy > month +Life expectancy < years +Patients with life expectancy of =< months for reasons other than their underlying hematologic/oncologic disorder +At least -month life expectancy. +Life expectancy > years based on clinicians judgment +Life expectancy less than month +Patients with a life expectancy < months from co-existing disease other than the leukemia or RAEB +Patients may have received therapy for other malignancies, as long as they have completed therapy at least months prior to study entry and be deemed to have a life expectancy of at least years with regard to that malignancy +Life expectancy >= mos +Other serious medical conditions that may be expected to limit life expectancy to less than years (e.g., liver cirrhosis). +Life-expectancy based on comorbid conditions > years +Patients must have a life expectancy of >= months and a Karnofsky performance status >= +Life expectancy from a co-morbid illness > years +Known history of or concomitant malignancy likely to affect life expectancy in the judgment of the investigator +Life expectancy of at least years +Any available standard line of therapy known to be life-prolonging or life-saving +Life expectancy of at least weeks ( months) as determined by the treating physician. +Patients with life expectancy of =< months for reasons other than their underlying hematologic/oncologic disorder or complications there from +Anticipated life expectancy > months at the time of screening +Anticipated life expectancy > months at the time of screening +Life-expectancy of at least days +Life expectancy of at least months in the judgment of the physician +are eligible for any standard therapy known to be life prolonging or life saving +History of second malignancies with life expectancy of < years or requirement of therapy that would confound study results. This does not include the following: +Life expectancy >mo. +Any co-morbid condition that poses a greater threat to the patients life expectancy than the recurrent myeloma +No concurrent malignancy with a life expectancy of less than two years, or one that requires ongoing chemotherapeutic intervention at screening +Subject has concurrent severe or uncontrolled medical disease or organ system dysfunction which, in the opinion of the Investigators, would limit life expectancy to < months. +Anticipated life expectancy > months at the time of screening +Not eligible for or declined transplantation or any standard therapy known to be life prolonging or life saving +Patients life expectancy is >= years +Patients with other active malignancies (no evidence of other cancer or life expectancy greater than years) are ineligible for this study +Life expectancy of at least month +Life expectancy of at least months in the judgment of the physician +No co-existing medical conditions with life expectancy < years +PATIENT EXCLUSION: Life expectancy of < month +Patients must have a life expectancy of days +Must have a life expectancy > days +There are no restrictions related to performance status or life expectancy +Patients with a life expectancy of =< months, as determined by their oncology providers, will be excluded +Patients are eligible regardless of life expectancy +PATIENTS ONLY: Physician-rated life expectancy of less than months +Attending physician assessment of prognosis with expected life expectancy of > months +Severe co-existing morbidities having a life expectancy of less than days +No life expectancy restriction +There are no restrictions related to performance status or life expectancy +Has a life expectancy of months or longer; all cancer types are included +There are no restrictions related to performance status and life expectancy +Life expectancy >= days +Have a life expectancy > months from the anticipated time of initiation of treatment +Participants must have a life expectancy of years or more +>= months life expectancy (physician estimate) +No restrictions will be made based on life expectancy +Life expectancy less than years +EXCLUSION CRITERIA FOR ENROLLMENT (PRE-TRANSPLANT): Non-hematologic malignancy with a life expectancy of < years +Suffering from a terminal illness with less than month life expectancy +Terminal illness with less than month life expectancy +Subjects with a life expectancy less than study duration; +Life expectancy < months or Lansky score <% +Life expectancy of >= years +Life expectancy less than five years. +Patients with anticipated life expectancy < months will be excluded +Life expectancy < months (mo) +Patients being considered for RALP and pelvic lymphadenectomy with life expectancy greater than years as determined by treating physician +Life expectancy >= years +There are no life expectancy restrictions +Subject must have a life expectancy that exceeds the duration of the clinical trial +Individuals with a short life expectancy (< years) +There are no restrictions on life expectancy +Life expectancy is not a consideration for protocol entry +Life expectancy of >= months (as determined by treating physician) +A referring physicians estimate of patient life expectancy must be between - months +Patients with life expectancy of at least months and who are expected to be able to complete the full follow-up assessment in the protocol. +Patients with distant metastatic disease (cM) or a life expectancy of less than years