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+++ b/clusters/9knumclustersv2/clust_1306.txt
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+Current severe, uncontrolled systemic disease other than cancer
+Current severe, uncontrolled systemic disease
+Evidence of severe or uncontrolled systemic diseases
+Current severe, uncontrolled systemic disease (for example [e.g.] clinically significant cardiovascular, pulmonary, or metabolic disease)
+Current severe, uncontrolled systemic disease (e.g., clinically significant cardiovascular, pulmonary, or metabolic disease) or intercurrent illness that could interfere with per-protocol evaluations.
+Current severe, uncontrolled systemic disease (including, but not limited to, clinically significant cardiovascular, pulmonary, or renal disease) other than cancer
+Current severe, uncontrolled systemic disease (e.g., clinically significant cardiovascular, pulmonary, or metabolic disease)
+Severe, uncontrolled systemic disease at screening;
+Current severe or uncontrolled systemic disease
+Evidence of severe or uncontrolled systemic diseases:
+Current severe, uncontrolled systemic disease
+Any evidence of severe or uncontrolled systemic diseases
+Any evidence of severe or uncontrolled systemic disease such as clinically significant cardiovascular, pulmonary, hepatic, renal or metabolic disease
+Current severe, uncontrolled systemic disease
+Severe, uncontrolled systemic disease
+Current severe, uncontrolled systemic disease
+Evidence of severe or uncontrolled systemic disease or HIV infection
+Severe and uncontrolled disease, including:
+Current severe, uncontrolled systemic disease (e.g., clinically significant cardiovascular, pulmonary, thyroid, or metabolic disease; wound healing disorders; ulcers; or bone fractures)
+Current severe, uncontrolled systemic disease (e.g., clinically significant cardiovascular, pulmonary, or metabolic disease)
+Current severe, uncontrolled systemic disease
+Other current, severe, uncontrolled systemic disease (e.g., clinically significant\n             metabolic disease, wound healing disorders, ulcers)
+As judged by the investigator any evidence of severe or uncontrolled systemic disease
+Current severe, uncontrolled systemic disease
+Current severe, uncontrolled non-cancer systemic disease (e.g., clinically significant cardiovascular, pulmonary, or metabolic disease) resulting in a life expectancy of <  months
+Severe or uncontrolled systemic infection
+Current severe, uncontrolled systemic disease (e.g. clinically significant cardiovascular, pulmonary, or metabolic disease; wound healing disorders; ulcers; bone fractures)
+Current severe, uncontrolled systemic disease (including but not limited to clinically significant cardiovascular, pulmonary, or renal disease or ongoing or active infection) excluding the cancer under study
+Current severe, uncontrolled systemic disease
+Current severe, uncontrolled systemic disease
+Current severe, uncontrolled systemic disease
+Current severe, uncontrolled systemic disease