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+Prior radiotherapy to the abdomen or pelvis
+Prior radiotherapy to the upper abdomen
+Prior radiation therapy to the abdomen that would overlap with treatment field
+Prior radiation treatment to the upper abdomen
+History of prior radiation therapy to the upper abdomen
+Previous radiation therapy to the lungs and/or to the upper abdomen
+Prior radiotherapy to the upper abdomen or radioembolization of the liver
+Prior radiotherapy to the pelvis (or abdomen if para-aortic nodes are involved)
+No prior radiotherapy to the upper abdomen
+Prior radiation therapy to the upper abdomen or liver
+Any prior radiotherapy to the pelvis or abdomen
+Prior radiation therapy to the abdomen or pelvis
+Prior radiation to the pelvis or abdomen in the metastatic or locally advanced setting.
+Metastatic disease outside the confines of the abdomen and pelvis (such as lung, bone, brain)
+Prior radiotherapy to the pelvis or abdomen
+Received or will receive radiation therapy to the abdomen or pelvis in the week prior to study drug administration and/or during the course of the study
+Previous radiotherapy delivered to the upper abdomen.
+Any history of metastatic TCC; subjects with suspected malignant lymphadenopathy in the abdomen or pelvis are not allowed
+Receipt of radiation to the abdomen for any reason during the planned -day treatment time
+Acute abdomen
+Ongoing radiation induced diarrhea or constipation or planned radiotherapy to the abdomen or pelvis while on study
+Prior radiotherapy to the upper abdomen/liver
+Has received or will receive total body irradiation of radiation therapy to the abdomen or pelvis in the week prior to Treatment Day  and/or during the diary reporting period ( hours following initiation of chemotherapy)
+Patient must not have undergone major surgery or radiotherapy to the pelvis or abdomen within previous  weeks
+Radiotherapy to the abdomen or pelvis within  months of the screening visit
+Any and all primary disease sites in the abdomen and pelvis will be allowed
+Patients must have no previous radiation to the abdomen