--- a
+++ b/clusters/9knumclustersv2/clust_1234.txt
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+Evidence of bleeding diathesis or clinically significant coagulopathy
+Patients with uncontrolled coagulopathy or bleeding disorder are not eligible
+Known bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Participants with active bleeding disorder/coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+History of bleeding diathesis or coagulopathy
+Evidence of bleeding diathesis or clinically significant coagulopathy.
+Bleeding disorder/coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+History of tumor-related or other serious hemorrhage, bleeding diathesis, or underlying coagulopathy
+No coagulopathy or bleeding diathesis
+Evidence of bleeding diathesis or coagulopathy
+Evidence of bleeding diathesis or coagulopathy
+Uncontrolled coagulopathy or bleeding disorder
+Clinical evidence of bleeding diathesis or coagulopathy
+Patients with uncontrolled coagulopathy or bleeding disorder
+Evidence of bleeding diathesis or coagulopathy
+Patients who have clinical history of coagulopathy, bleeding diathesis or thrombosis within the past year
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Inherited bleeding diathesis or coagulopathy with the risk of bleeding
+Patients with uncontrolled coagulopathy or bleeding disorder
+REGORAFENIB EXCLUSION CRITERIA: Evidence or history of bleeding diathesis or coagulopathy
+History of or genetic predisposition to a bleeding diathesis or coagulopathy
+Evidence of bleeding diathesis or coagulopathy
+Evidence of bleeding diathesis or coagulopathy
+Patients who have clinical history of coagulopathy, bleeding diathesis or thrombosis within the past year
+Evidence of clinically significant bleeding diathesis or underlying coagulopathy, non-healing wound
+The subject has inherited bleeding diathesis or coagulopathy with the risk of bleeding
+Evidence of bleeding diathesis, coagulopathy as documented by an elevated PT, PTT or bleeding time
+Clinical evidence of bleeding diathesis or coagulopathy
+History or evidence of inherited bleeding diathesis or coagulopathy with a risk of bleeding
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence of bleeding diathesis or coagulopathy (including clinically significant hemoptysis)
+Evidence of active bleeding diathesis or coagulopathy\r\n* For the NSCLC expanded cohort only: history of blood tinged sputum allowed
+Patients with uncontrolled coagulopathy or bleeding disorder
+History of abnormal bleeding and coagulopathy
+Bleeding or evidence or history of clinically significant bleeding diathesis or coagulopathy within the last  months
+Clinically significant bleeding diathesis or coagulopathy
+History or evidence of inherited bleeding diathesis or coagulopathy with a risk of bleeding
+Evidence or history of bleeding diathesis or coagulopathy
+Patients with a known coagulopathy or bleeding diathesis or require the use of systemic anticoagulant medication are not eligible
+Evidence of bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence of bleeding diathesis or coagulopathy
+Patient has a coagulopathy or bleeding disorder
+Evidence or history of bleeding diathesis or coagulopathy
+Patients must not have a known bleeding diathesis or coagulopathy
+Evidence of bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+No significant bleeding within the past  months; no bleeding diathesis or coagulopathy
+Evidence of bleeding diathesis or coagulopathy.
+Evidence of bleeding diathesis or coagulopathy
+Patients are excluded if they have evidence of bleeding diathesis or coagulopathy
+Evidence of bleeding diathesis or coagulopathy
+Known bleeding disorder or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+History or evidence of inherited bleeding diathesis or coagulopathy with the risk of bleeding
+Evidence or history of bleeding diathesis or coagulopathy.
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence of bleeding diathesis or coagulopathy
+Evidence of bleeding diathesis or coagulopathy within the past  months
+Evidence of bleeding diathesis or coagulopathy within  months
+Patients with a history of hemoptysis, bleeding diathesis, known platelet disorder, or coagulopathy are not eligible
+Evidence of bleeding diathesis or clinically significant coagulopathy
+Evidence of prior or current coagulopathy or bleeding diathesis
+Clinically-significant evidence of bleeding diathesis or coagulopathy as so judged by the treating physician
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Pre-existing bleeding diathesis, coagulopathy or hemorrhage
+The subject has inherited bleeding diathesis or coagulopathy with the risk of bleeding
+Patients must have no known bleeding diathesis or coagulopathy that would make intratumoral injection or biopsy unsafe.
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence of bleeding diathesis or clinically significant coagulopathy
+Evidence of bleeding diathesis or a clinically significant coagulopathy
+Patients with an active, bleeding diathesis or significant coagulopathy
+History of bleeding diathesis or coagulopathy. (Patients on stable anticoagulant therapy are eligible.)
+Patient has a coagulopathy or bleeding disorder which is uncontrolled.
+Evidence of bleeding diathesis or significant coagulopathy
+Patients with uncontrolled coagulopathy or bleeding disorder
+Evidence or history of bleeding diathesis or uncontrolled coagulopathy
+Evidence or history of a bleeding diathesis or coagulopathy, including therapy-induced coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Concurrent use of anti-coagulant drugs (not including prophylactic doses), history of coagulopathy, or evidence of bleeding diathesis or coagulopathy
+Presence of bleeding diathesis or coagulopathy
+No known bleeding diathesis or coagulopathy
+History of bleeding diathesis or coagulopathy
+Coagulopathy or bleeding diathesis
+Evidence of bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy.
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence of clinically significant bleeding diathesis or coagulopathy
+Active GI bleeding and any bleeding diathesis or coagulopathy that is not correctable by usual therapy or hemostatic agents
+Known bleeding disorder or coagulopathy
+Evidence of clinically significant bleeding diathesis or underlying coagulopathy (e.g. INR > . without vitamin K antagonist therapy), non-healing wound
+Patients must not have a bleeding diathesis, hereditary of acquired bleeding disorder or coagulopathy
+History of bleeding diathesis or coagulopathy other than that due to anticoagulation therapy
+Evidence or history of bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy at the time of enrollment
+History or evidence of inherited bleeding diathesis or coagulopathy with a risk of bleeding and active gastrointestinal bleeding
+Evidence or history of bleeding diathesis or coagulopathy
+History of tumor-related or other serious hemorrhage, bleeding diathesis, or underlying coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Any evidence of bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Clinically significant bleeding diathesis or coagulopathy, including known platelet function disorders
+Evidence or history of bleeding diathesis or coagulopathy
+Known bleeding diathesis or coagulopathy
+Evidence or history of bleeding diathesis or coagulopathy
+Known bleeding diathesis or coagulopathy
+History of coagulopathy or bleeding disorders
+Known inherited bleeding disorder or coagulopathy
+Severe coagulopathy or bleeding disorder
+Patient must not have a known bleeding diathesis or coagulopathy