WOCBP who are unwilling or unable to use an acceptable method of avoiding pregnancy for the entire study period

Patients who are otherwise felt unable to comply with the protocol, in the opinion of the investigator

Subject is unable or unwilling to participate a study related procedure

In the opinion of the Investigator patient is unable or unwilling to comply with the protocol.

Patients unable to comply with instructions for DIBH

Patients must not be pregnant or breast feeding, or unable or unwilling to use proper contraception during the study and up to 3 months following study completion (for treatment phase)

Patients unwilling to or unable to comply with the protocol

Patient unable or unwilling to comply with the protocol requirements

Patients who are unwilling to comply with protocol

Patients unwilling to or unable to comply with the protocol

Unable/unwilling to undergo bone marrow sampling

Unwilling or unable to comply with the requirements of the study protocol

Patients unable or unwilling to abide by the study protocol or cooperate fully with the investigator

Unwilling or unable to provide written informed consent, comply with study requirements, or be available for follow-up assessments

Patients unable to comply with the protocol

Assessed by the investigator to be unable or unwilling to comply with the requirements of the protocol

Subjects must be unwilling or unable to tolerate other non-study systemic chemotherapy.

DONOR: Donors who are unwilling or unable to sign informed consent (assent when appropriate)

Patient is unwilling or unable to comply with study procedures, or is planning to take vacation for 7 or more consecutive days during the treatment phase of the study without prior consent from the medical monitor

Unwilling or unable to follow protocol requirements

For female patients of childbearing potential (defined as having had a menstrual period within the past 12 months): a positive serum pregnancy test (?-human chorionic gonadotropin [? HCG]) within 7 days prior to enrollment; or unwilling or unable to undergo hormonal suppression to avoid menstruation during treatment; or if breastfeeding, unwilling or unable to stop breastfeeding while on study treatment.

Patients unable or unwilling to adhere to the study assessment schedule.

Patients unwilling or unable to comply with the study protocol.

Unwilling or unable to participate in all required study evaluations and procedures

Unwilling or unable to participate in all required study evaluations and procedures

Unwilling or unable to follow protocol requirements

The subject or guardian is unable to give informed consent or unable to comply with the treatment protocol including appropriate supportive care, follow-up and research tests.

Unwilling or unable to participate in all required study evaluations and procedures

Unwilling or unable to follow protocol requirements

Patients unwilling to or unable to comply with the protocol

Patients unwilling or unable to comply with the protocol

Unwilling or unable to follow protocol requirements

Patients unwilling or unable to comply with the protocol

Unwilling or unable to follow protocol requirements

Patients assessed by the investigator to be unable or unwilling to comply with the requirements of the protocol

Unwilling or unable to follow protocol requirements.

Patient or guardian unable to give informed consent or unable to comply with the treatment protocol including appropriate supportive care, follow-up, and research tests.

Patients unwilling or unable to comply with the protocol

Subject is unable or unwilling to abide by the study protocol or cooperate fully with the Investigator or designee.

Unable or unwilling to sign the consent form

Unwilling or unable to follow protocol requirements

Unable or unwilling to sign the consent form

Patient or guardian unable to give informed consent or unable to comply with the treatment protocol including appropriate supportive care, long-term follow-up, and research tests.

The subject is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Unwilling or unable to provide informed consent or comply with the requirements of this protocol, including the presence of any condition (physical, mental or social) that is likely to affect the subject's return for scheduled visits and follow-up.

Unwilling or unable to follow protocol requirements

Patients who are unwilling or unable to comply with all study requirements

Patients unwilling or unable to comply with the protocol.

Patients who are unwilling or unable to undergo an apheresis for production of their vaccine

Patients unable or unwilling to provide informed consent.

Patients unable or unwilling to return to the transplant center for their assigned treatments.

Unwilling or unable to follow protocol requirements

Unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee.

Unwilling or unable to follow protocol requirements

Patients unable or unwilling to abide by the study protocol or cooperate fully with the investigator

Patients unable or unwilling to undergo a biopsy for research during the screening period, 2-3 weeks into the course of therapy and at the time of progression

Unable or unwilling to discontinue concomitant use of drugs that are known to prolong the QT interval.

Unwilling or unable to follow protocol requirements

Unable to read or understand, and/or unwilling to sign a written consent form which must be obtained prior to treatment.

Patients unable or unwilling to give written, informed consent.

Patients unwilling to comply with study protocol

Unable or unwilling to sign the consent form

Patient is unwilling or unable to comply with study procedures

Unwilling or unable to participate in all required study evaluations and procedures

Unable or unwilling to follow post-therapy radiation protection procedures

Patients are not eligible if they are unwilling or unable to comply with the protocol

Unable to comply with the requirements of the protocol, or unable to provide adequate informed consent in the opinion of the principal investigator

Is unwilling or unable to comply with study requirements

Unwilling or unable to participate in all required study evaluations and procedures

WOCBP who are unwilling or unable to use an acceptable method to minimize the risk of pregnancy for the entire study period and for at least 23 weeks after the last dose of investigational product

Patient is unwilling or unable to follow the study schedule for any reason

Unwilling or unable to follow protocol requirements

Patients unwilling or unable to comply with the protocol

Unwilling or unable to follow protocol requirements

Unwilling or unable to participate in all required study evaluations and procedures

Patients unwilling to or unable to comply with the protocol

Unable or unwilling to communicate or cooperate with the Investigator or follow the protocol for any reason

Patients who, in the investigator's judgment, are unwilling or unable to consent to and return for recommended post-treatment scans as outlined in this study

Unwilling or unable to participate in all required study evaluations and procedures

DONOR: Unwilling or unable to provide informed consent

Unable or unwilling to sign the consent form

Unwilling or unable to follow protocol requirements

Subjects who are unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee are excluded

Patients unwilling or unable to comply with the protocol

Patient is unable or unwilling to sign consent

Patients unwilling to or unable to comply with the protocol

Unable or unwilling to communicate or cooperate with the Investigator or follow the protocol for any reason

Unable or unwilling to swallow the complete daily dose of ARQ 751

Unwilling or unable to participate in all required study evaluations and procedures

Unable or unwilling to tolerate an intracranial MRI

Subject is unable or unwilling to discontinue use of prohibited medications

Subject is unable or unwilling to participate in a study related procedure

Patient is unwilling or unable to follow the study schedule for any reason

Patients who are not available for follow-up assessments or unable to comply with study requirements

Unwilling or unable to stop oral supplemental vitamin D

Unable to comply with protocol

The subject is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Unwilling or unable to provide informed consent

Patients unwilling or unable to comply with the protocol

Patients unwilling or unable to comply with the protocol

Patients unwilling or unable to comply with the protocol

The subject is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Unwilling or unable to follow protocol requirements

Unable or unwilling to swallow ARQ 092 or anastrozole or comply with chemotherapy regimen

Unable or unwilling to sign the consent form

Patients unwilling or unable to comply with the protocol

Unwilling or unable to comply with the safety monitoring requirements of this protocol

Patients unwilling or unable to comply with the protocol

Patients unwilling to or unable to comply with the protocol

Unwilling or unable to follow protocol requirements

Unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Patient is unable or unwilling to abide by the study protocol or cooperate fully with the investigator

Unwilling or unable to follow protocol requirements

Unable or unwilling to sign the consent form

Unwilling or unable to follow protocol requirements

Patients who are unwilling or unable to comply with study and/or follow-up procedures

Patients unwilling or unable to comply with the protocol

The subject is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Patient is unable or unwilling to abide by the study protocol or cooperate fully with the investigator

Patients unable or unwilling to swallow pills

Patients unwilling or unable to comply with the protocol

Unable to render informed consent and to follow protocol requirements

The subject is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Patients is unwilling or unable to comply with study procedures

Unwilling or unable to follow protocol requirements

Patient is unable or unwilling to provide written informed consent or comply with follow-up schedule

Unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Patients unwilling or unable to comply with the protocol

Unwilling or unable to follow protocol requirements

Unwilling or unable to follow protocol requirements

Unwilling or unable to follow protocol requirements

Unwilling or unable to, comply with the protocol

Patients unwilling or unable to sign informed consent document

Patients unwilling or unable to sign informed consent document

Patients unwilling to or unable to comply with the protocol

Patient or guardian unable to give informed consent or unable to comply with the treatment protocol including appropriate supportive care, follow-up and research tests

Patients unwilling or unable to comply with the outlined protocol

Patient unwilling to or unable to comply with the protocol

Unable or unwilling to give voluntary informed consent/assent

Patient or guardian unable to give informed consent or unable to comply with the treatment protocol including appropriate supportive care, follow-up, and research tests

Unable or unwilling to sign the consent form

Assessed by the Investigator to be unable or unwilling to comply with the requirements of the protocol.

Unwilling or unable to follow protocol requirements

Unable to provide informed consent or, in the opinion of the Principal Investigator, comply with the protocol.

Unwilling or unable to complete study diary

Are unable or unwilling to follow protocol instructions and requirements

Is, in the judgment of the investigator, unable or unwilling to comply with the requirements of the study.

Unable or unwilling to undergo a 7 day washout period if currently being treated with deferiprone or deferoxamine or deferasirox;

Patient is unable or unwilling to abide by the study protocol or cooperate fully with the investigator

Patients who are unwilling or unable to use 2 highly effective methods of contraception as outlined in this protocol

Patients unwilling or unable to comply with the protocol, or provide informed consent.

Unable or unwilling to adhere to the study-specified procedures and restrictions

Patients who are unable to provide informed consent, are incarcerated, or are unable to follow protocol requirements.

Unwilling or unable to follow protocol requirements

Patients unwilling to or unable to comply with the protocol

Adults unable to consent

Patients unwilling or unable to comply with the protocol, or provide informed consent

Patients unwilling or unable to comply with the protocol, or provide informed consent

The subject is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Unwilling or unable to follow protocol requirements

Patients with untreated AML who are either unwilling or unable to undergo high-dose induction/consolidation intensive chemotherapy

The subject is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Unwilling or unable to participate in all required study evaluations and procedures

Patients who are unable or unwilling to abide by the study protocol or to cooperate fully with the investigator or designee

WOCBP who are unwilling or unable to use an acceptable method to avoid pregnancy for the entire study period and for up to 8 weeks after the last dose of investigational product

Patients unwilling or unable to comply with the study protocol

Unable and unwilling to provide informed consent

Patients unwilling to or unable to comply with the protocol

Unwilling or unable to follow protocol requirements

Unwilling or unable to follow protocol requirements

Patient is unable or unwilling to abide by the study protocol or cooperate fully with the investigator

Unable to comply with the requirements of the protocol, or unable to provide adequate informed consent in the opinion of the principal investigator

Unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Unable or unwilling to undergo protocol required thromboembolism prophylaxis(for Cohort C, this will be only for the subjects who have a history of VTE)

Is unable or unwilling to take folic acid or vitamin B12 supplementation.

Subjects unwilling to or unable to comply with the protocol

Patients who are unable to swallow oral medication or are unwilling to comply with the administration requirements are not eligible

Unwilling or unable to follow protocol requirements

Unwilling or unable to follow protocol requirements

Unwilling or unable to participate in all required study evaluations and procedures

Subject is unwilling or unable to comply with study procedures

Patients unwilling or unable to comply with this study protocol

Patients unwilling or unable to comply with the protocol

Unwilling or unable to follow protocol requirements or to give informed consent

Unwilling or unable to participate in all required study evaluations and procedures

Unwilling or unable to participate in all required study evaluations and procedures

Patients unwilling or unable to comply with the protocol

Unwilling or unable to comply with the protocol or cooperate fully with the investigator and site personnel

Subject is unwilling or unable to comply with study procedures

Patients unable to comply with the protocol as judged by the investigator.

Patients unwilling or unable to comply with the protocol

Patients unwilling to or unable to comply with the protocol

WOCBP who are unwilling or unable to use an acceptable method to minimize the risk of pregnancy for the entire study period and for at least 12 weeks after the last dose of investigational product

Patient unable to consent or comply with study guidelines

Patients unwilling or unable to comply with the protocol

The subject is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Patients unwilling or unable to sign informed consent document.

Unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Is unable or unwilling to participate in a study related procedure

Patients unwilling to or unable to comply with the protocol.

Unable or unwilling to sign the informed consent document

Unwilling to or unable to comply with the protocol

Unwilling or unable to comply with the protocol

Subject is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Unwilling or unable to comply with the protocol

Patients unwilling or unable to comply with the protocol

Patients unable or unwilling to give written, informed consent

Unwilling or unable to follow protocol requirements

Unwilling or unable to comply with the protocol

Patients unwilling or unable to comply with the protocol

Patient is unwilling or unable to follow the study schedule for any reason

Patient is unable or unwilling to abide by the study protocol or cooperate fully with the investigator

Male subjects unable or unwilling to use adequate contraception methods from study start to 30 days after the last dose of protocol therapy

Unable or unwilling to undergo antithrombotic prophylaxis

Unwilling or unable to undergo a MRI or CT Scan per study protocol requirements

Unwilling or unable to follow protocol requirements

Is unable to comply with study requirements

Unable to consent for study

Assessed by the investigator to be unable or unwilling to comply with the requirements of the protocol

Unable to give informed consent or comply with clinical trial requirements

Patients unwilling or unable to provide informed consent for the study

Is unable to follow study procedures

Unwilling or unable to participate in all required study evaluations and procedures

Unwilling or unable to follow protocol requirements

Unwilling or unable to participate in all required study evaluations and procedures

Unwilling or unable to follow protocol requirements

Unwilling or unable to follow protocol requirements

Unwilling or unable to follow protocol requirements

Patient is unable or unwilling to abide by the study protocol or cooperate fully with the investigator

Patients unwilling to or unable to comply with the protocol

Participants unwilling or unable to comply with the protocol

Unable or unwilling to swallow the complete daily dose of ARQ 087

Patients unwilling or unable to sign informed consent document

Patients who are not available for follow-up assessments or unable to comply with study requirements

Patient unable to comply with the protocol, in the opinion of the investigator.

Male subjects unable or unwilling to use adequate contraception methods from study start to one year after the last dose of protocol therapy

Patient or guardian unable to give informed consent or unable to comply with the treatment protocol including appropriate supportive care, follow-up, and research tests

Male subjects unable or unwilling to use adequate contraception methods from study start to one year after the last dose of protocol therapy

The participant is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Male subjects unable or unwilling to use adequate contraception methods from study start to one year after the last dose of protocol therapy

Patients unwilling to or unable to comply with the protocol

Unwilling or unable to follow protocol requirements

WOCBP who are unwilling or unable to use an acceptable method to avoid pregnancy for the entire study and for up to 8 weeks after the last dose of investigational product

Patients unwilling or unable to comply with the protocol

Unable or unwilling to sign the consent form

The subject is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Patient is unable or unwilling to abide by the study protocol or cooperate fully with the investigator

Patients unwilling to or unable to comply with the protocol

Patients unwilling or unable to sign informed consent document

Patient is unable or unwilling to discontinue predefined prohibited medications listed in the protocol for 4 weeks of a drug (whichever is longer) prior to Visit 1 and for the duration of the study

Patients unwilling or unable to comply with protocol therapy, tests, and visits, or with a history of noncompliance with medical regimens

EXPANSION COHORT ONLY: Patient is unable or unwilling to discontinue predefined prohibited medications listed in the protocol for 4 weeks of a drug (whichever is longer) prior to visit 1 and for the duration of the study

EXPANSION COHORT ONLY: Patients unwilling or unable to comply with protocol therapy, tests, and visits, or with a history of noncompliance with medical regimens

Unwilling or unable to participate in all required study evaluations and procedures

Patients unwilling to comply with the protocol

Unable or unwilling to provide informed consent.

Unable or unwilling to adhere to the study-specified procedures and restrictions

Subjects unwilling to or unable to comply with the protocol procedures as assessed by the Investigator

Subject unwilling or unable to comply with study requirements

Patient or guardian unable to give informed consent or unable to comply with the treatment protocol including appropriate supportive care, follow-up and research tests

Patients unwilling or unable to comply with the protocol

Is unwilling or unable to abide by the requirements of the study.

Unwilling or unable to participate in all required study evaluations and procedures.

Patient is unable or unwilling to abide by the study protocol or cooperate fully with the investigator

Patients unable to comply with the protocol

Subject is unwilling or unable to comply with study procedures.

WOCBP who are unwilling or unable to use an acceptable method to avoid pregnancy for the entire study period and for up to 8 weeks after the last dose of chemotherapy

Unwilling or unable to follow protocol requirements

Unwilling or unable to follow protocol requirements

Unwilling or unable to follow protocol requirements

Unable or unwilling to take folic acid or vitamin B12

Unable or unwilling to complete the follow-up evaluations required for the study

Unwilling or unable to follow protocol requirements and the light exposure precautions

Unwilling or unable to follow protocol requirements

Patient is unwilling or unable to comply with study procedures

Unable to comply with the study follow-up schedule

The subject is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Patient is unwilling or unable to comply with study procedures

Patient unable or unwilling to comply with the protocol requirements

Male subjects unable or unwilling to use adequate contraception methods from study start to one year after the last dose of protocol therapy

The subject is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Unwilling or unable to follow protocol requirements

Patients unwilling or unable for any reason (personal, medical, or psychiatric) to comply with the protocol

Patients unwilling or unable to comply with the study protocol

Unwilling or unable to undergo a MRI per requirements in the study protocol

The subject is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Patient unable or unwilling to comply with the protocol.

Subjects unable or unwilling to comply with the study visit schedule and requirements of the study

Subjects who are unable or unwilling to comply with all study requirements for clinical visits, examinations, tests, and procedures.

Woman of childbearing potential unwilling or unable to use adequate contraception

Unwilling or unable to take oral medication

Unwilling or unable to participate in all required study evaluations and procedures

Patient is unwilling or unable to comply with the follow-up schedule

Patients unwilling or unable to comply with the research protocol

In Part 2, unable or unwilling to consent to provision of tumor tissue for GR assay

Is unwilling or unable to comply with study procedures, or is planning to take a vacation for 7 or more consecutive days during the treatment phase of the study

Unable or unwilling to comply with all protocol requirements.

Unwilling to, or unable to, comply with the protocol

Unwilling or unable to follow protocol requirements

Assessed by the investigator to be unable or unwilling to comply with the requirements of the protocol

Patients unwilling to use contraceptives while on study

Unable or unwilling to abide by the study protocol or cooperate fully with the investigator

Patients unwilling or unable to comply with the protocol

The subject is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

The subject is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Patient is unable to comply with the requirements of the study.

Patients unwilling to or unable to comply with the protocol

WOCBP who are unwilling or unable to use an acceptable method to avoid pregnancy for the entire study period and for up to 12 weeks after the last dose of investigational product

Unwilling or unable to have a central venous catheter

Subjects unable or unwilling to undergo antithrombotic prophylactic treatment

Patient is unable or unwilling to abide by the study protocol or cooperate fully with the investigator

Patients unable to comply with the protocol

Patients who are unwilling or unable to comply with the protocol are not eligible

The subject is unable or unwilling to abide by the study protocol or cooperate fully with the investigator or designee

Patients unwilling to or unable to comply with the protocol

Patients who are unable or unwilling to undergo antithrombotic therapy.

Subject is unwilling or unable to follow the procedures outlined in the protocol.

Unwilling or unable to follow protocol requirements

Patients unwilling or unable to comply with the protocol

Patients who are unwilling or unable to comply with the protocol

Unwilling or unable to follow protocol requirements

Unwilling or unable to follow protocol requirements

Unwilling or unable to follow protocol requirements

Unwilling or unable to comply with the protocol

Unwilling or unable to participate in the study

Unable to comply with the protocol for any reason

Unwilling or unable to follow protocol requirements

Unwilling or unable to follow protocol requirements

Unwilling or unable to participate in the study

Unwilling or unable to participate in the study

Unwilling or unable to participate in the study

Unwilling to give consent

Unable or unwilling to discontinue consuming soy-based food or supplements while participating in this study

Anyone who, in the investigator’s discretion, would be unwilling or unable to comply with study procedures

Unable and unwilling to provide informed consent

Unwilling to give consent

Unwilling to undergo routine follow-up

Are unable or unwilling to discontinue anxiolytics within 4 hours of education sessions

Subjects who are unable or unwilling to discontinue use of prohibited medications

Unable to cooperate with research procedures

Unwilling to receive acupuncture or unable to travel for treatments

Unable or unwilling to sign consent

Unwilling or unable to participate in the study

Unwilling or unable to follow protocol requirements

Unable or unwilling to give written informed consent

Patients unable to apply Estring

Unable/unwilling to sign consent

Unwilling or unable to follow protocol requirements

Unwilling or unable to provide informed consent or comply with the requirements of this protocol, including the presence of any condition (physical, mental or social) that is likely to affect the subject's return for scheduled visits and follow-up.

Unwilling or unable to comply with the protocol

Unable or unwilling to abide by the study protocol or cooperate fully with the Investigator or designee.

Unwilling or unable to participate in all required study evaluations and procedures

Unwilling or unable to participate in all required study evaluations and procedures

The patient is unwell or unable to participate in all required study evaluations and procedures

Unwilling or unable to provide informed consent

Unable to comply with protocol and/or not available for follow-up assessments

Unwilling or unable to follow protocol requirements

Be unable or unwilling to discontinue anxiolytic medication within 4 hours of intervention sessions

Is unwilling or unable to agree to swish and spit the study oral rinse three times per day during the study period

Unwilling or unable to sign and date the informed consent

Unwilling or unable to comply with the follow-up schedule

Patients unwilling or unable to comply with the protocol

Unable to comply with the protocol for any reason

Unable or unwilling to comply with study procedures

Patients unable to consent for the procedure

Patients unwilling or unable to provide consent

Unwilling or unable to provide consent

Adults unable to consent

Patient unable to comply with the treatment protocol including appropriate supportive care, follow-up and research tests

EXCLUSION CRITERIA (PRIOR TO IBRUTINIB ADMINISTRATION): Unwilling or unable to participate in all required study evaluations and procedures

Unwilling or unable to follow protocol requirements

Patient or guardian unable to give informed consent or unable to comply with the treatment protocol including appropriate supportive care, follow-up and research tests

Patients unwilling to comply with study requirements

Unable to understand instruction and to follow protocol requirements

Unwilling or unable to follow protocol requirements

Unable or unwilling to provide informed consent

Unable or unwilling to adhere to study-specified procedures

Subjects unable or unwilling to comply with the study visit schedule and requirements of the study

Patients unwilling or unable to comply with the study protocol

Unable or unwilling to adhere to a carbohydrate-restricted dietary intervention

If, in the opinion of the Investigator, the patient is deemed unwilling or unable to comply with the requirements of the Study

Patient unwilling or unable to provide informed consent.

Unwilling or unable to follow the protocol requirements.

Subjects unwilling or unable to given written informed consent

Subject is unwilling to comply with the requirements of the protocol

Patients unwilling or unable to sign informed consent

Unwilling or unable to follow protocol requirements

Subject is unable or unwilling to follow study requirements, including signed consent or assent

Participants unable or unwilling to give written, informed consent or to undergo MRI imaging

Unable or unwilling to give informed consent

Patients unable or unwilling to provide informed consent

Subjects that are unable or unwilling to give informed consent

Unwilling or unable to follow protocol requirements

Unable or unwilling to give informed consent

Patients who are unable to give consent

Unable or unwilling to discontinue concomitant drugs that are known to prolong the QT interval

Unable to understand, or unwilling to complete the informed consent process

Unable or unwilling to follow protocol requirements

Patient under guardianship and/or unable or unwilling to cooperate with the requirements of this trial

Patient is unable (or unwilling) to provide informed or surrogate (as appropriate) consent

Subjects who are unable or unwilling to give informed consent

Unable/unwilling to follow protocol requirements

Unwilling or unable to follow protocol requirements

Unwilling or unable to follow protocol requirements

Are unwilling or unable to participate in, or do not have tissue adequate for participation in the biomarker analyses in the study.

Unwilling or unable to participate in the study

Unwilling or unable to receive home health care

Are unable to consent

Patients who are unable or unwilling to give informed consent

Men whose partner is unwilling or unable to avoid pregnancy