The patient has known and active alcohol or drug dependency
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
Clinically significant history of liver disease, including active viral or other hepatitis, current alcohol abuse, or cirrhosis
Known significant mental illness or other condition, such as active alcohol or other substance abuse or addiction, that in the opinion of the investigator predisposes the subject to high risk of noncompliance with the protocol.
Ongoing alcohol or drug addiction
History of illicit drug or alcohol abuse within 12 months prior to screening
Current alcohol or drug abuse.
History of drug or alcohol abuse within past 5 years.
Is a regular user as determined by investigator judgment (including \recreational use\) of any illicit drugs or has a recent history (within the last year) of substance abuse (including alcohol), at the time of signing informed consent.
Ongoing alcohol or drug addiction
History of alcohol abuse
History of or ongoing alcohol abuse that, in the opinion of the investigator, would compromise compliance or impart excess risks associated with study participation
Participants with an unstable major psychiatric disorder, as assessed by study clinician, or a diagnosis of alcohol abuse (more than 5 drinks in a 24 hour period) or substance dependence within the past 1 year (as determined by a standard psychiatric interview) will be excluded unless otherwise approved by the PI or PI’s designee
Patient with history of poor compliance or history of drug/alcohol abuse, or excessive alcohol beverage consumption that would interfere with the ability to comply with the study protocol, or current or past psychiatric disease that might interfere with the ability to comply with the study protocol or give informed consent
Known or suspected active drug or alcohol use
Active substance abuse
Is a regular user of any illicit drugs or had a recent history of substance abuse
Alcohol dependency within 6 months before study entry
Known alcohol or drug abuse that would preclude compliance with study procedures.
Any condition (e.g. psychological, geographical, etc.) that does not permit compliance with the protocol, including patients with history of poor compliance or history of drug/alcohol abuse, or excessive alcohol beverage consumption that would interfere with the ability to comply with the study protocol. Patients planning to take a vacation for 14 or more consecutive days during the course of the study are ineligible.
Patients with current alcohol or drug abuse
Documented History of Alcoholism and or drug abuse
Is, at the time of signing informed consent, a regular user (including \recreational use\) of any illicit drugs or has a recent history (within the last year) of substance abuse (including alcohol).
Known or suspected history of significant drug abuse as judged by the Investigator
Evidence of current drug or alcohol abuse or psychiatric impairment, which in the investigator’s opinion will prevent completion of the protocol therapy or follow-up
No active alcohol addiction (as assessed by medical caregiver)
Participants with active alcohol abuse, as determined by the investigator
Known current drug or alcohol abuse
History of active alcohol or drug abuse
Known current alcohol or drug abuse.
Patient with clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis.
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
Known alcohol or drug abuse
History of, suspected, or known addiction to or abuse of illicit drug(s), prescription medicine(s), or alcohol within the past 2 years.
History of active ethanol abuse
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
Known alcohol or drug abuse within the last 1 year.
Active alcohol or drug abuse
Currently under alcohol or drug abuse rehabilitation or treatment program
Alcohol or drug abuse as judged by study physicians
Clinically significant history of liver disease, including cirrhosis and current alcohol abuse
Active, uncontrolled psychiatric disorders or substance (drug/alcohol) abuse that interfere with patient’s safety, ability to provide informed consent, or ability to comply with the protocol
History of alcohol abuse.
Has known psychiatric or substance abuse disorders that would interfere with cooperation with the requirements of the trial; at the time of signing informed consent is a known regular user (including \recreational use\) of any illicit drug(s) or had a recent history (within the last year) of drug or alcohol abuse
Alcohol or drug dependence
Admission or evidence of illicit drug use, drug abuse, or alcohol abuse.
Known to have recent history of drug abuse or alcoholism.
Known alcohol or drug abuse
History of alcohol abuse.
Patients with current alcohol or drug abuse
Evidence of current chronic alcohol or drug abuse;
History of alcohol or other substance abuse within the last year.
History of alcohol abuse within 2 years of registration
Known significant mental illness or other conditions such as active alcohol or other substance abuse/addiction that, in the opinion of the investigator, predisposes the subject to high risk of noncompliance with the protocol
Known drug or alcohol abuse;
Known alcohol or drug abuse
Known alcohol or drug abuse
Known alcohol or drug abuse
Known alcohol or drug abuse
Subjects with active alcohol or drug addiction that would interfere with their ability to comply with the study requirements
Patients in active alcohol withdrawal
Clinically significant liver disease, including active viral or other hepatitis, current alcohol abuse, or cirrhosis
Known alcohol or drug abuse
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
Known drug or alcohol abuse
Willingness to abstain from alcohol or any alcohol-containing fluids for the duration of the study
Known alcohol or drug abuse within the last 1 year
Active alcohol or drug abuse
Is, at the time of signing informed consent, a regular user (including “recreational use”) of any illicit drugs or had a recent history (within the last year) of substance abuse (including alcohol)
Active drug/alcohol dependence or abuse history
Active alcohol or drug abuse
Known alcohol or drug abuse
Known clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
Subjects with a known hypersensitivity to fulvestrant or any of its formulation components including castor oil, alcohol, benzyl alcohol, and benzyl benzoate.
Known current drug abuse or alcohol abuse
Patients who are at the time of signing informed consent, a regular user of any illicit drugs, substance abuser or who have a recent history of drug or alcohol abuse
Use of alcohol or drug use that may interfere with the patient's ability to participate in the study.
Patient with a known diagnosis of ongoing alcoholism/alcohol abuse
History suggestive of substance abuse
Patient has alcohol or substance abuse which, in the opinion of the investigator, would interfere with compliance or safety
Active alcohol or drug abuse
History of alcohol abuse
Meet criteria for the following psychiatric and/or substance use disorders as assessed by the MINI International Neuropsychiatric Interview (MINI): items C (current manic or hypomanic episode only), I (alcohol abuse - Alcohol Addendum - past 6 months only; current alcohol dependence), J (substance abuse - Substance Abuse Addendum - past 6 months only; current substance dependence), K (current psychotic disorder or current mood disorder with psychotic features); individuals who meet criteria for non-exclusionary psychiatric disorders that are considered clinically unstable and/or unsuitable to participate as determined by the principal investigator and/or study physician
Testing positive on a urine drug screen for drugs of abuse/potential abuse
Ongoing alcohol use or abuse defined as > an average of 2 alcoholic beverages daily
Regular user (including \recreational use\) of any illicit drugs or recent history (within the last year) of substance abuse (including alcohol)
Patient is, at the time of signing informed consent, a regular user (including illicit drugs or had a recent history (within the last year) of substance abuse (including alcohol)
History of alcohol or other substance abuse or dependence within the year prior to registration
History of alcohol abuse or illicit drug use within 12 months of study initiation
Patient is, at the time of signing informed consent, a regular user of any illicit drugs or had a recent history (within the last year) of drug or alcohol abuse
History of alcohol abuse or illicit drug use within 12 months of study initiation
History of alcohol abuse
Known significant mental illness or other condition such as active alcohol or other substance abuse or addiction that, in the opinion of the investigator, predisposes the subject to high risk of noncompliance with the protocol.
History of chronic liver disease, veno-occlusive disease, or current alcohol abuse
Patients with known addiction to alcohol or illicit drugs
Known drug or alcohol abuse.
Recent history of drug or alcohol abuse that could, in the opinion of the investigator, affect adherence to the study protocol
Current alcohol abuse syndrome
Active alcohol abuse syndrome
Current alcohol dependence or drug abuse.
Current alcohol dependence or drug abuse.
Substance or alcohol abuse or dependence, within 12 months prior to screening.
Known or suspected substance abuse or alcohol abuse
No active alcohol addiction (as assessed by medical caregiver)
Patients with known sensitivity to alcohol.
Treatment for drug or alcohol dependence during the last year, or evidence of alcohol abuse so severe that the patient is judged potentially unable to comply with the protocol.
Active alcohol dependence
Current abuse of alcohol or illicit drugs.
Known drug abuse/ alcohol abuse
Patients with known active or history of chronic hepatitis C and/or B infection, and active alcohol or drug abuse are not eligible
Active drug or alcohol use or dependence that would interfere with study compliance
Known significant mental illness or other condition such as active alcohol or other substance abuse or addiction that, in the opinion of the investigator, predisposes the subject to high risk of noncompliance with the protocol.
Illicit drug or alcohol abuse within 12 months prior to screening
Evidence of current drug or alcohol abuse or psychiatric impairment, which in the investigator’s opinion will prevent completion of protocol therapy or follow-up
Unable to abstain from alcohol for the duration of the study
Past or present history of active substance abuse (drug or alcohol)
Untreated psychiatric illness, including drug/alcohol abuse, that would compromise compliance
Known or suspected active drug or alcohol abuse
Current alcohol misuse/abuse within the past 12 months
Patient is, at the time of signing informed consent, a regular user (including \recreational use\) of any illicit drugs, substance abuse or had a recent history (within the last year) of drug or alcohol abuse
History of active substance or alcohol abuse within the last year
History of active substance or alcohol abuse within the last year
Has known psychiatric or substance abuse disorders that would interfere with cooperation with the requirements of the trial. Is a known regular user (including \recreational use\) of any illicit drug(s) or had a recent history (within the last year) of drug or alcohol abuse.
Known alcohol or drug abuse
Known significant mental illness or other conditions such as active alcohol or other substance abuse that, in the opinion of the investigator, predisposes the subject to high risk of noncompliance with the protocol treatment or assessments.
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
History of drug abuse
Is a regular user (including \recreational use\) of any illicit drugs or had a recent history (within the last year) of substance abuse (including alcohol).
Ongoing alcohol or drug addiction
Known alcohol or drug abuse
Current abuse of alcohol or drugs
Psychiatric disorders and substance (drug/alcohol) abuse
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
History of alcohol or substance abuse
Have a known history of drug abuse.
Active alcohol or active drug abuse as judged by the investigator.
Patients who have a history of alcohol or drug abuse in the 6 month period prior to study treatment.
Is, at the time of signing informed consent, a regular user (including \recreational use\) of any illicit drugs or had a recent history (within the last year) of substance abuse (including alcohol)
Known or suspected active drug or alcohol abuse.
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
History of any hepatitis (e.g. alcohol or non-alcohol steatohepatitis (NASH), drug- related, autoimmune)
Known drug or alcohol abuse
No history of or current active drug/alcohol dependence
Active drug/alcohol dependence or abuse history
Any history of drug or alcohol dependency or abuse within the prior 6 months
Known alcohol or drug abuse
Active alcohol or drug abuse
No active alcohol or drug abuse
Subject has addictive/substance abuse problems.
History of any hepatitis (e.g., alcohol or non-alcohol steatohepatitis [NASH], auto immune, or grade 3-4 drug-related hepatitis)
History of acute pancreatitis within 1 year prior to registration, chronic pancreatitis, alcohol abuse or uncontrolled hypertriglyceridemia (triglycerides > 450 mg/dL)
Patient is, at the time of signing informed consent, a regular user (including “recreational use”) of any illicit drugs or other substance abuse (including alcohol) that could potentially interfere with adherence to study procedures or requirements
Known or suspected active drug or alcohol abuse
Current alcohol dependence or drug abuse.
Current alcohol or chemical abuse, or mental or psychiatric condition precluding protocol compliance
Patient has an Alcohol Use & Dependence (AUDIT) score of < 10
Patient is, at the time of signing informed consent, a regular user (including “recreational use”) of any illicit drugs or had a recent history (within the last year) of substance abuse (including alcohol)
Known or suspected active drug or alcohol abuse
Phase 1b subject has a positive drug or alcohol urine test at screening visit.
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
Known alcohol or drug abuse
Known or suspected active alcohol or drug abuse.
History of excessive alcohol consumption
Have a recent history of alcoholism; former alcoholics who have abstained from alcohol for 5 years or more may be enrolled in this study
Have an active chemical or alcohol dependency as assessed by the investigator
Patients who have history of drug or alcohol abuse within 12 months prior study dosing.
Current alcohol or drug abuse
Have a history of pancreatitis or alcohol abuse
Known alcohol or drug abuse.
Active alcohol abuse
History of drug or alcohol abuse within the 12 months prior to enrollment.
Known presence of alcohol and/or drug abuse.
Known presence of alcohol and/or drug abuse.
Subjects who are known to be actively abusing alcohol or drugs
Known alcohol or drug abuse.
Ongoing alcohol or drug addiction
Documented history of alcohol, cocaine or intravenous drug abuse =< 6 months of enrollment
Untreated psychiatric illness, drug/alcohol abuse
Is a regular user of any illicit drugs or had a recent history of substance abuse
Current alcohol dependence or drug abuse.
Has any serious medical or psychiatric illness, including drug or alcohol abuse.
Active alcohol or drug abuse
Known or suspected active drug or alcohol abuse
Subject has a documented history of substance abuse (narcotics, alcohol, etc.) or substance dependency in the 6 months prior to baseline data collection
A history of pancreatitis or alcohol abuse
Clinically significant history of liver disease, including cirrhosis and current alcohol abuse
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
Have a history of alcohol of substance abuse, unless in full remission for greater than 6 months prior to the screening visit (day 0) when the consent form is signed
Active substance abuse
Clinically significant history of liver disease, including viral or other known hepatitis, current alcohol abuse, or cirrhosis
Ongoing alcohol or drug addiction
History of alcohol or substance abuse, unless in full remission for more than 6 months prior to start of study treatment
Ongoing alcohol or drug addiction
Drug abuse, alcohol abuse, or other factors that in the opinion of the investigator could affect the ability of the subject to comply with the requirements of the protocol.
Known or suspected active drug or alcohol abuse
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
Active alcohol abuse or other illness or circumstance that carries a likelihood of inability to comply with study treatment and follow-up or otherwise compromise the study’s objectives
Known current drug or alcohol abuse
Known or suspected active drug or alcohol abuse;
Active alcohol or drug abuse
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
Current alcohol dependence or drug abuse.
Patients with a history of alcohol abuse, or patients unwilling or unable to remain completely abstinent of alcohol during the study period
PART I: Participants who consume an excess of alcohol or abuse drugs (an excess of alcohol is defined as more than four of any one of the following per day: 30 mL distilled spirits, 340 mL beer, or 120 mL wine) will not be allowed
PART II: Those who consume an excess of alcohol or abuse drugs (an excess of alcohol is defined as more than four of any one of the following per day: 30 mL distilled spirits, 340 mL beer, or 120 mL wine) will not be allowed
Known or suspected alcohol abuse
Known current drug or alcohol abuse
Current user of any illicit drugs (including marijuana) or current evidence of alcohol abuse
History or presence of alcoholism or drug abuse within the past 2 years
Subjects may not have known current drug or alcohol abuse
A positive pre-study drug/alcohol screening (testing at time of screening is not required).
Known clinically significant history of liver disease consistent with Child-Pugh Class B or C, including active viral or other hepatitis, current drug or alcohol abuse, or cirrhosis
Alcohol abuse problems make patients INELIGIBLE; patients need to be consuming less than or equal to 14 units of alcohol weekly
Clinically significant liver disease, including active viral, alcoholic or other hepatitis, cirrhosis, or current alcohol abuse
History of any hepatitis (e.g., alcohol or non-alcohol steatohepatitis (NASH), drug-related, auto-immune)
Donor must not have active alcohol or substance abuse within 6 months of study entry.
Recipient must have no active alcohol or substance abuse within 6 months of study entry.
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
Known or suspected active alcohol or drug abuse.
Patients with active alcohol abuse, as determined by the treating investigator.
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
Patients who have a history of alcohol or drug abuse in the 6 month period prior to receiving treatment with pasireotide or RAD001
History of, or current alcohol misuse/abuse within the past 12 months
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
History of drug abuse
History of alcohol or drug abuse within 6 months prior to screening.
Alcohol consumption within 30 days of first study treatment, or refusing to abstain from alcohol for the duration of study treatment
Evidence of current drug or alcohol abuse or psychiatric impairment, which in the Investigator’s opinion will prevent completion of the protocol therapy or follow-up
History of alcohol abuse
In the opinion of the principal investigator (PI), has a history of drug or alcohol abuse within last 12 months
History of any hepatitis (e.g., alcohol or non-alcohol steatohepatitis [NASH], auto immune, or grade 3-4 drug-related hepatitis)
Self-reported active alcohol or substance abuse within the last 30 days
Active substance abuse or dependence
Conditions that may affect the patient’s ability to participate in this trial, e.g. known or suspected active alcohol or drug abuse
Clinically significant history of liver disease, including viral or other hepatitis, current alcohol abuse, or cirrhosis
Known alcohol or drug abuse
History of substance abuse.
Are in treatment for substance abuse (e.g., illicit drugs, alcohol abuse)
They endorse active addiction to another substance (e.g., illicit drugs or alcohol)
History of substance abuse
History of substance abuse
Illicit substance abuse within the past 6 months
History of substance abuse
History of alcohol abuse
Current acknowledged use of any illicit drugs, medical marijuana (including Marinol), or evidence of alcohol abuse as defined by The American Psychiatric Association criteria; this includes patients who are currently in the recovery process
Current alcohol or narcotic abuse
Alcohol or drug abuse
Patients with suspected or confirmed poor compliance, mental instability, or prior or current alcohol or drug abuse deemed by the investigator to be likely to affect their ability to sign the informed consent, or undergo study procedures will be excluded
Substance abuse or dependence or met criteria within past year
Active substance abuse at time of registration (alcohol, drugs, non-prescription use of controlled substances)
Patients with history of alcohol or substance abuse by using Cut-down, Annoyed, Guilty, Eye-opener adapted to include Drug use questionnaire (CAGE-AID) score of 2 or higher
Recent active excessive alcohol or illicit drug use
Breast cancer survivors (BCS) with other major disabling medical, psychiatric, or substance abuse conditions (e.g., anxiety, depression, alcohol/tobacco problems) will be excluded
Current alcohol or drug abuse (may exacerbate lethargy/dizziness with memantine)
Subjects with active alcohol or drug addiction that would interfere with their ability to comply with the study requirements
Past history of sexual abuse
Free of current ethanol (ETOH) or drug abuse
History of opioid abuse
Current acknowledged use of any illicit drugs or evidence of alcohol abuse as defined by the American Psychiatric Association criteria
Ongoing or recent history of drug abuse.
Participant has current reported illicit drug or alcohol abuse or dependence
Current acknowledged use of any illicit drugs or evidence of alcohol abuse as defined by The American Psychiatric Association criteria
untreated alcohol or substance abuse or dependence, bipolar, or psychotic disorder
No history of or current active drug/alcohol dependence
History of or active drug/alcohol dependence or abuse
Current alcohol or drug abuse
History or current diagnosis of substance abuse or dependence
Current documented alcohol abuse or illicit drug substance abuse
Active alcohol or substance abuse issue
Chronic alcohol abuse (> 6 alcoholic beverages daily)
Concurrent illness, such as known psychiatric disorders or substance abuse (i.e., average alcohol consumption of more than 3 drinks per day), which in the opinion of the investigators would compromise either the patient or the integrity of the data
Concurrent illness, such as known psychiatric disorders or substance abuse (i.e., average alcohol consumption of more than 5 drinks per day), which in the opinion of the investigators would compromise either the patient or the integrity of the data
Current excessive alcohol consumption (average alcohol consumption of more than 5 drinks per day)
Known history of dependency/abuse of psychopharmaceuticals, alcohol, illicit drugs or narcotics
Does not have a recent history of alcohol or drug abuse or is in treatment
History of alcohol or other substance dependence or current abuse
History of alcohol or other substance dependence or current abuse
Blood alcohol level > 0.01 (one re-screen allowed)
Meet criteria for the following psychiatric and/or substance use disorders as assessed by the Mini International Neuropsychiatric Interview (MINI): items C (current manic or hypomanic episode only), I (alcohol abuse - alcohol addendum-past 6 months only; current alcohol dependence), J (substance abuse - substance abuse addendum - past 6 months only; current substance dependence), K (psychotic disorder or mood disorder with psychotic features); individuals who meet criteria for non-exclusionary psychiatric disorders that are considered clinically unstable and/or unsuitable to participate as determined by the principal investigator
Other known drug use/abuse
History of alcohol or drug dependence in the past year
Meet criteria for the following psychiatric and/or substance use disorders as assessed by the Mini International Neuropsychiatric Interview (MINI); items C (current manic or hypomanic episode only), I (alcohol abuse-Alcohol Addendum-past 6 months only; current alcohol dependence), J (substance abuse-Substance Abuse Addendum-past 6 months only; current substance dependence), K (current/lifetime psychotic disorder or current/lifetime mood disorder with psychotic features); individuals who meet criteria for non-exclusionary psychiatric disorders that are considered clinically unstable and/or unsuitable to participate as determined by the principal investigator and/or study physician
Concurrent excessive alcohol consumption (average alcohol consumption of more than 5 drinks per day)
History of chronic alcohol use or abuse defined as any one of the following: a) average consumption of 3 or more alcohol containing beverages daily in the past 12 months; b) consumption of 7 or more alcoholic beverages within a 24 hour (hr) period in the past 12 months
Alcohol or illicit drug dependence within the past 12 months (by history and urine tests)
Willing to use alcohol in moderation while taking study agent
Recent history (within 6 months) of alcoholism or drug abuse
Patients with history of chronic alcohol use
Ongoing alcohol abuse
Subjects with drug, alcohol, or substance abuse reported within the last three years (subject reported);
Participants with bleeding diathesis, history of gastric/duodenal ulcers in the last 5 years, NSAID-precipitated bronchospasm, patients unwilling or unable to limit alcohol consumption to i.e. =< 3 alcohol drinks a day
Have a history of alcohol or substance abuse, unless in full remission for greater than 6 months prior to the screening visit (day 0) when the consent form is signed
Is currently a user of any recreational or illicit drugs (including marijuana) or has current evidence of drug or alcohol abuse or dependence
Is a user of recreational or illicit drugs or has a recent history (<=1 year) of drug or alcohol abuse or dependence
History of alcohol or drug dependency in the past year
Has a history of drug or alcohol abuse within 1 year of study enrollment as determined by the investigator.
With current substance abuse and/or history of substance abuse, as per medical records or patient report
History of substance abuse
History of alcoholism or other substance abuse
Has a history of alcohol abuse or alcohol dependency in the 3 years before study entry, or is an alcoholic or drug addict, as determined by the investigator
Substance abuse within the past 2 years
Known alcohol or drug abuse
Current or recent (within 12 months) problems with drug use or alcohol dependence by self-report
Alcohol dependence, abuse, or history of dependence/abuse by self-report
Current or recent (within three months) alcohol or drug abuse problems, including marijuana use within prior year, assessed via the Drug Use Questionniare-1 month
Known alcohol or drug abuse
Current or recent (within the past 3 months) alcohol or drug abuse problems (to ensure alcohol and drug use does not affect biomarkers of exposure and to maximize retention)
History of ongoing alcohol abuse or binge drinking; alcohol abuse will be defined as a pattern of drinking that results in harm to one’s health, interpersonal relationships, and ability to work; binge drinking will be defined as at least one episode of consuming more than five units in men and four units in women during the previous month; one unit of alcohol can generally said to be a half pint of beer, a single measure (shot glass) of a spirit or a small glass of table wine
Current or recent (within 12 months) problems with drug use or alcohol dependence by self-report
Alcohol dependence, abuse, or history of dependence/abuse by self-report
any major current psychiatric impairment, including current alcohol/drug abuse/dependence
The participant has known drug or alcohol abuse.
The participant has known drug or alcohol abuse.