--- a +++ b/clusters/3009knumclusters/centers.txt @@ -0,0 +1,300 @@ +Cluster 0: cypa strong inhibitors inducers cytochrome subfamily family polypeptide medications moderate +Cluster 1: infection requiring systemic active therapy antibiotics antibiotic intravenous treatment days +Cluster 2: transaminase serum aminotransferase glutamic oxaloacetic sgot sgpt upper normal pyruvate +Cluster 3: bilirubin mg dl total syndrome gilberts gilbert serum direct unless +Cluster 4: investigational participated study device participating currently agent weeks therapy dose +Cluster 5: phase ii patients aim prior expansion cohort portion study treatment +Cluster 6: creatinine clearance min ml serum mg dl estimated uln crcl +Cluster 7: consent informed procedures study specific provide written prior signed ability +Cluster 8: metastasis brain leptomeningeal known distant patients symptomatic suspected cns evidence +Cluster 9: expectancy life weeks greater patients estimated years equal investigator year +Cluster 10: women contraception men childbearing potential use adequate unwilling pregnant study +Cluster 11: cardiac significant disease arrhythmia function history impaired arrhythmias requiring uncontrolled +Cluster 12: hiv positive known immunodeficiency virus human infection patients cd aids +Cluster 13: contraceptive use potential effective reproductive method study methods men agreed +Cluster 14: qtc interval qt msec corrected prolongation ecg electrocardiogram prolonged milliseconds +Cluster 15: males females years age older aged time consent old non +Cluster 16: hemoglobin dl transfusion days mmol prior transfusions registration erythropoietin transfused +Cluster 17: hgb hemoglobin dl transfusion achieve intervention acceptable days note use +Cluster 18: hemoglobin dl mmol gm hb mg greater level weeks phase +Cluster 19: platelets mm cells days anc prior transfusion registration obtained plt +Cluster 20: received prior therapy patients treatment previously systemic days study weeks +Cluster 21: heart angina myocardial infarction unstable congestive failure cardiac months uncontrolled +Cluster 22: hepatitis virus immunodeficiency hiv human infection known active hcv hbv +Cluster 23: cancer cell basal squamous adequately skin treated years situ malignancy +Cluster 24: granulocyte colony stimulating csf factor count mm absolute factors macrophage +Cluster 25: surgery prior patients weeks days radiation patient major treatment planned +Cluster 26: breast cancer invasive diagnosis prior patients inflammatory metastatic carcinoma dcis +Cluster 27: pregnancy lactation breastfeeding current test positive women testing time standards +Cluster 28: neutrophil absolute count anc mm cells days registration prior support +Cluster 29: signed informed consent written form dated patient guardian study document +Cluster 30: ecog performance status appendix patients score scale equal adequate patient +Cluster 31: feeding breast pregnant women females pregnancy female patients lactating planning +Cluster 32: samples research provide purposes correlative blood willing tissue mandatory willingness +Cluster 33: corticosteroids inhaled topical steroids systemic prednisone immunosuppressive mg doses daily +Cluster 34: ps ecog performance eastern cooperative oncology group status score scale +Cluster 35: bone marrow function adequate involvement cells blood biopsy patients prior +Cluster 36: organ transplant history allogeneic solid allograft allografts corneal marrow bone +Cluster 37: childbearing potential pregnancy test negative female serum females urine prior +Cluster 38: illness compliance social requirements psychiatric intercurrent situations uncontrolled limit study +Cluster 39: platelets ul plt ml microliter cells days transfusion registration prior +Cluster 40: mcl platelets days initiation performed treatment registration prior transfusion obtained +Cluster 41: bilirubin upper normal limit total uln institutional times gilberts syndrome +Cluster 42: ul platelet count lymphocyte neutrophils transfusion independent days obtained prior +Cluster 43: measurable disease evaluable lesion patients non defined cm lesions criteria +Cluster 44: pregnant women excluded study patients planning currently female females patient +Cluster 45: grade toxicity alopecia toxicities prior therapy related recovered resolved previous +Cluster 46: platelet mm count days cells transfusion prior transfusions obtained independent +Cluster 47: interstitial lung pneumonitis disease history evidence active infectious pulmonary ild +Cluster 48: contraception methods intrauterine barrier device method use condom potential effective +Cluster 49: therapy steroid immunosuppressive form systemic receiving immunodeficiency diagnosis dose days +Cluster 50: therapies prior received number anti patients therapy cancer anticancer treatment +Cluster 51: rituximab containing prior therapy treatment regimen refractory months received chemotherapy +Cluster 52: effects recovered prior toxic therapy acute fully grade chemotherapy radiotherapy +Cluster 53: pressure mmhg blood systolic diastolic hypertension bp uncontrolled controlled antihypertensive +Cluster 54: pd programmed anti death ligand cell lymphocyte ctla antibody cytotoxic +Cluster 55: bleeding diathesis active history disorder disorders gastrointestinal known significant evidence +Cluster 56: hemorrhage intracranial stroke months history enrollment prior hemoptysis study dose +Cluster 57: fraction ejection left ventricular lvef cardiac echocardiogram shortening lower normal +Cluster 58: willingness understand sign ability written document informed consent subjects subject +Cluster 59: aminotransferase ast alt aspartate alanine uln upper normal limit times +Cluster 60: eastern cooperative oncology group ecog performance status karnofsky score scale +Cluster 61: bowel gastrointestinal malabsorption resection vomiting absorption nausea small significantly disease +Cluster 62: pneumonitis organizing fibrosis idiopathic pneumonia induced pulmonary history chest obliterans +Cluster 63: transplant stem cell allogeneic autologous prior hematopoietic months received patients +Cluster 64: inr normalized ratio international time uln prothrombin pt thromboplastin partial +Cluster 65: days prior registration study therapy treatment dose radiotherapy enrollment growth +Cluster 66: study pregnant inform suspect immediately agree contraception woman barrier duration +Cluster 67: histologically confirmed cytologically adenocarcinoma diagnosis prostate metastatic cancer nsclc cell +Cluster 68: compliance psychological safety condition protocol study conditions psychiatric medical procedures +Cluster 69: staff medical regimens conduct history noncompliance compliance study planning non +Cluster 70: concurrent therapy investigational agents chemotherapy cancer treatment use immunotherapy anti +Cluster 71: ct pet tomography scan computed emission positron imaging mri disease +Cluster 72: vaccines live attenuated influenza flu seasonal allowed inactivated intranasal vaccine +Cluster 73: mcl neutrophil absolute count anc days initiation performed treatment registration +Cluster 74: mm longest measured measurable accurately lesion dimension diameter ct recorded +Cluster 75: bacterial fungal viral infection active uncontrolled infections systemic requiring antibiotics +Cluster 76: patients eligible study excluded therapy prior treated treatment receiving receive +Cluster 77: hodgkin lymphoma non nhl cell refractory relapsed classical autologous confirmed +Cluster 78: english read speak speaking able understand write spanish ability language +Cluster 79: imaging resonance magnetic mri ct tomography computed scan disease brain +Cluster 80: inability comply procedures unwillingness follow protocol study swallow requirements pills +Cluster 81: hepatitis positive virus hcv antibody hbv antigen surface infection test +Cluster 82: ctcae grade nci neuropathy hemorrhage version event bleeding diarrhea alopecia +Cluster 83: trial confound best abnormality results interfere participate laboratory duration current +Cluster 84: vascular peripheral aortic disease aneurysm significant arterial repair thrombosis collagen +Cluster 85: organ function adequate marrow defined hematologic end laboratory bone days +Cluster 86: brain metastases known patients treated stable trial excluded clinical evidence +Cluster 87: protein urine ratio mg hour serum light dl proteinuria chain +Cluster 88: illness medical psychiatric interfere condition prevent opinion abnormality potentially likely +Cluster 89: carcinoma cell skin basal squamous situ malignancy years cervix treated +Cluster 90: expecting conceive trial projected screening children father visit breastfeeding duration +Cluster 91: monoclonal antibody reaction hypersensitivity severe history antibodies reactions infusion mab +Cluster 92: half lives shorter whichever investigational prior weeks days drug therapy +Cluster 93: disease progression progressive patients evidence leptomeningeal therapy refractory treatment prior +Cluster 94: participant research study received treatment therapy prior disease receiving investigator +Cluster 95: sarcoma soft tissue ewing oncogene homolog tumor diagnosis confirmed rhabdomyosarcoma +Cluster 96: albumin dl serum mg days initiation treatment performed gm registration +Cluster 97: unable unwilling protocol comply follow requirements study consent patients abide +Cluster 98: live vaccine days attenuated received prior dose study vaccination receipt +Cluster 99: tissue tumor biopsy archival available sample slides obtained fresh paraffin +Cluster 100: leukemia aml promyelocytic acute apl mds myeloid diagnosis myelodysplastic patients +Cluster 101: immunodeficiency hiv virus human known positive infection history antibodies acquired +Cluster 102: platinum based chemotherapy regimen disease progression therapy line prior resistant +Cluster 103: contraindication contrast mri hypersensitivity known drugs allergy concomitant including gadolinium +Cluster 104: surgically childbearing sterile potential abstain heterosexual activity sterilized study subjects +Cluster 105: limits normal institutional bilirubin total upper creatinine serum potassium uln +Cluster 106: chemotherapy prior received cytotoxic patients regimen treatment cancer regimens systemic +Cluster 107: bilirubin uln total direct serum syndrome gilbert gilberts levels subjects +Cluster 108: normal limit upper creatinine uln serum times institutional alt ast +Cluster 109: lactating pregnant women females female patients breastfeeding study excluded subject +Cluster 110: alcohol abuse drug history substance current known dependence active illicit +Cluster 111: risk high intermediate ipss mds prognostic scoring international patients disease +Cluster 112: healing wound fracture ulcer non bone presence major days active +Cluster 113: diagnosed newly cancer malignancy patients years previously disease nonmelanoma residual +Cluster 114: therapy prior anti chemotherapy systemic cancer hormonal treatment patients radiation +Cluster 115: weeks earlier administered adverse events recovered agents prior entering study +Cluster 116: recist measurable disease version criteria defined according lesion evaluable based +Cluster 117: inhibitor prior treatment kinase therapy received parp mek cdk mtor +Cluster 118: radiation therapy prior weeks chemotherapy treatment patients study received palliative +Cluster 119: white wbc blood cell cells ul count mm mcl days +Cluster 120: stage iv iii cancer disease ajcc melanoma ii breast nsclc +Cluster 121: bmi mass index body kg obese overweight greater patients weight +Cluster 122: function adequate liver renal marrow bone kidney defined hematological inadequate +Cluster 123: tumor biopsy primary cm patients biopsies solid accessible size resection +Cluster 124: aptt activated thromboplastin partial ptt anticoagulant intended anticoagulants time pt +Cluster 125: receptor er ihc negative estrogen positive progesterone hybridization fish breast +Cluster 126: tuberculosis tb bacillus active known history previous clinical diagnosis latent +Cluster 127: inclusion criteria apply meet registration cohort patients additional specific protocol +Cluster 128: infections active uncontrolled requiring antibiotics systemic illnesses opportunistic patients medical +Cluster 129: cr remission complete induction response aml leukemia pr patients relapse +Cluster 130: heparin low molecular weight warfarin anticoagulation therapeutic aspirin dose lmwh +Cluster 131: concurrently investigational receiving agents study patients therapy treatment agent using +Cluster 132: glioma world organization grade health glioblastoma diagnosis histologically confirmed iv +Cluster 133: contraception use effective agree potential study childbearing male method female +Cluster 134: drug study dose days administration prior weeks investigational therapy experimental +Cluster 135: ischemic transient thrombosis attack cerebrovascular accident deep months embolism history +Cluster 136: qt long syndrome congenital history family qtc interval msec corrected +Cluster 137: cancer diagnosis lung ovarian small cell primary center patients non +Cluster 138: pembrolizumab excipients hypersensitivity severe known grade epacadostat substance active history +Cluster 139: months survival prior past expected enrollment study history treatment therapy +Cluster 140: pulmonary obstructive disease chronic severe requiring copd antibiotics hospitalization history +Cluster 141: common terminology adverse ctcae events grade criteria version institute national +Cluster 142: hla donor matched leukocyte antigen unrelated drb related typing human +Cluster 143: treatment prior previous study patients weeks therapy allowed dose anti +Cluster 144: consent informed able sign understand willing written form document patient +Cluster 145: fasting glucose mg dl mmol triglycerides cholesterol serum plasma diabetes +Cluster 146: agents investigational receiving patients currently participants study anti eligible cancer +Cluster 147: equal greater years age dl count platelets hemoglobin mm platelet +Cluster 148: inhibitors prior kinase treatment tyrosine therapy mtor patients use pik +Cluster 149: nervous central cns metastases active known untreated disease meningitis lymphoma +Cluster 150: hepatitis active infection known chronic hiv history positive viral patients +Cluster 151: step registration prior randomization days eligibility crossover criteria dl patients +Cluster 152: pneumonitis infectious non history steroids required current evidence active known +Cluster 153: egfr alk mutation tki exon kinase mutations epidermal receptor treatment +Cluster 154: leukemia acute plasma chronic cell lymphoblastic myeloid myelogenous lymphoma cml +Cluster 155: response criteria recist solid evaluation tumors measurable disease version evaluable +Cluster 156: capacity forced predicted dlco carbon monoxide fev expiratory volume diffusing +Cluster 157: test pregnancy negative urine serum positive female hours confirmed study +Cluster 158: laboratory values parameters clinical following abnormalities study places clia range +Cluster 159: fcbp agree contact sexual vasectomy condom latex successful potential lenalidomide +Cluster 160: absorption gastrointestinal gi interfere disease alter oral malabsorption significantly disorders +Cluster 161: diabetes mellitus type uncontrolled controlled poorly ac insulin hbac glucose +Cluster 162: autoimmune disease active history systemic past requiring suspected vitiligo immunosuppressive +Cluster 163: major surgery weeks prior study days recovered drug dose effects +Cluster 164: hamster chinese ovary hypersensitivity recombinant products antibodies known human cell +Cluster 165: stable dose decreasing corticosteroids prior days patients weeks corticosteroid enrollment +Cluster 166: time pt prothrombin thromboplastin ptt partial inr uln normalized ratio +Cluster 167: consent informed written voluntary sign guidelines nature legal accordance patients +Cluster 168: month prior therapy study investigational treatment patients enrollment hemoptysis use +Cluster 169: hormone releasing lhrh luteinizing therapy agonist thyroid androgen orchiectomy gnrh +Cluster 170: investigational agent days treatment study prior weeks received drug receiving +Cluster 171: hypersensitivity known excipients components history component drugs study formulation excipient +Cluster 172: weeks prior radiotherapy therapy chemotherapy study treatment dose nitrosoureas mitomycin +Cluster 173: illness pectoris social situations intercurrent arrhythmia uncontrolled compliance congestive limited +Cluster 174: pugh child class score hepatic impairment cirrhosis liver severe classification +Cluster 175: advanced locally metastatic unresectable disease histologically cancer confirmed solid recurrent +Cluster 176: creatinine calculated clearance min ml serum measured uln crcl mg +Cluster 177: allergy known hypersensitivity components history study excipients formulations drug formulation +Cluster 178: score karnofsky lansky performance years age patients kps ambulatory wheelchair +Cluster 179: bearing child potential pregnancy test women negative pregnant serum female +Cluster 180: retinal rvo occlusion vein history evidence current retinopathy serous risk +Cluster 181: following criteria meet patients treatment disease prior therapy defined progression +Cluster 182: history primary immunodeficiency disease prior known hypertensive pancreatitis leptomeningeal patients +Cluster 183: hepatitis reactive qualitative hbsag rna detected hcv ribonucleic surface acid +Cluster 184: creatinine uln serum times institutional renal days registration obtained prior +Cluster 185: lymph node nodes axillary sentinel cm biopsy dissection disease regional +Cluster 186: significant clinically disease cardiac history uncontrolled pulmonary investigator active ecg +Cluster 187: seizure disorder history patients seizures medication brain requiring uncontrolled controlled +Cluster 188: adjuvant chemotherapy neoadjuvant therapy prior setting months metastatic neo treatment +Cluster 189: hypertension uncontrolled diabetes controlled despite pulmonary poorly history medical hypertensive +Cluster 190: pacemaker metal implanted clips implants mri metallic devices pacemakers aneurysm +Cluster 191: age years time patients consent donor men old lansky women +Cluster 192: liver uln disease metastases chronic cirrhosis alt ast hepatitis patients +Cluster 193: inappropriate make judgment study investigator severe interfere patient entry increase +Cluster 194: donor donors matched unrelated related blood cell infusion lymphocyte haploidentical +Cluster 195: nursing pregnant women female patients females excluded lactating study mothers +Cluster 196: mg dl creatinine serum years age maximum male calcium female +Cluster 197: hepatic function adequate renal marrow bone defined hematological coagulation cardiac +Cluster 198: breastfeeding pregnant women females female patients excluded patient subject study +Cluster 199: return follow institution enrolling willing monitoring phase active mayo study +Cluster 200: mri contrast undergo ct patients unable brain scan imaging contraindications +Cluster 201: filtration glomerular rate min ml gfr creatinine estimated clearance renal +Cluster 202: malignancy active years history concurrent treatment second prior requiring patients +Cluster 203: carcinoma cell squamous small urothelial adenocarcinoma histologically clear histology renal +Cluster 204: alkaline phosphatase uln limit normal upper liver alp times bone +Cluster 205: pelvic radiation prior radiotherapy irradiation previous abdominal therapy history patients +Cluster 206: hematologic function adequate renal hepatic inadequate coagulation liver defined toxicity +Cluster 207: autoimmune requiring psoriasis vitiligo diabetes recur hypothyroidism trigger type mellitus +Cluster 208: msec qtcf interval fridericia qt formula corrected ecg screening correction +Cluster 209: disease inflammatory bowel colitis autoimmune ulcerative history arthritis systemic lupus +Cluster 210: swallow capsules tablets able unable patients inability intact pills ability +Cluster 211: cord spinal compression brain metastases leptomeningeal untreated symptomatic stable disease +Cluster 212: expectancy life months greater estimated investigator opinion patients anticipated predicted +Cluster 213: involvement nervous central cns known active lymphoma leukemia patients malignancy +Cluster 214: creatinine institutional clearance normal levels min ml uln upper calculated +Cluster 215: recovered therapy prior grade note molecule complications targeted administered adequately +Cluster 216: neuropathy grade peripheral sensory pain motor greater existing higher patients +Cluster 217: immediate reaction hypersensitivity idiosyncrasy chemically delayed drugs related dmso excipients +Cluster 218: platelet count mcl days transfusion prior transfusions plt dl ml +Cluster 219: board review irb approved institutional consent informed sign understand written +Cluster 220: cancer skin non melanoma malignancy situ years carcinoma cervix invasive +Cluster 221: infection active uncontrolled patients ongoing antibiotics eligible presence evidence systemic +Cluster 222: composition compounds chemical similar attributed allergic reactions biologic history used +Cluster 223: products hypersensitivity blood known murine investigational tobacco containing study allergy +Cluster 224: contraception dose study agree male method adequate abstinence use starting +Cluster 225: karnofsky performance status kps scale score lansky patients greater ecog +Cluster 226: transaminase aminotransferase serum uln sgpt glutamic sgot alt oxaloacetic alanine +Cluster 227: cll lymphocytic sll leukemia chronic iwcll diagnosis lymphoma transformation treatment +Cluster 228: psa ng ml prostate rising progression value specific antigen prostatectomy +Cluster 229: years older age male female aged patients subjects time consent +Cluster 230: exclusion criteria registration apply cohort treatment specific patients tnbc pre +Cluster 231: myeloma multiple diagnosis relapsed refractory imwg therapy criteria working prior +Cluster 232: interfere results study interpretation condition medical investigator participation opinion evaluation +Cluster 233: oxygen air room pulse oximetry saturation supplemental rest dyspnea pulmonary +Cluster 234: cooperation substance abuse disorders interfere psychiatric requirements trial known study +Cluster 235: rems program revlimid registered mandatory comply willing requirements mitigation able +Cluster 236: myocardial infarction months angina unstable history prior coronary study stroke +Cluster 237: uncontrolled medical severe disease active infection conditions seizures concurrent disorder +Cluster 238: eligibility criteria medi phase cohort ii study cancer meet registration +Cluster 239: altered prohibit understanding mental rendering dementia consent informed status psychiatric +Cluster 240: oral medications able medication inability ability patients absorption gastrointestinal tolerate +Cluster 241: standard therapy care advanced solid metastatic refractory available histologically confirmed +Cluster 242: weight loss months hearing lbs body past pounds unintentional program +Cluster 243: opinion condition investigator medical study subject compromise patient participation safety +Cluster 244: comply visits procedures willing able study scheduled follow protocol ability +Cluster 245: mg equivalent prednisone day dose corticosteroids daily corticosteroid systemic steroids +Cluster 246: hcc hepatocellular diagnosis systemic carcinoma sorafenib prior fibrolamellar confirmed liver +Cluster 247: treated situ cancer adequately carcinoma curatively years curative intent malignancy +Cluster 248: antiretroviral combination hiv immunodeficiency positive ineligible virus human therapy patients +Cluster 249: metformin taking hypersensitivity reason subjects insulin currently known patients doxycycline +Cluster 250: muga fraction echocardiogram acquisition ejection scan gated left ventricular lvef +Cluster 251: abdominal perforation fistula gastrointestinal abscess intra history months obstruction gi +Cluster 252: women pregnancy test childbearing negative potential serum days prior urine +Cluster 253: cns metastases nervous central patients disease stable symptomatic treated brain +Cluster 254: lymphoma cell large follicular diffuse dlbcl mantle zone refractory marginal +Cluster 255: longer whichever half lives investigational drug days study prior treatment +Cluster 256: pd inhibitor ctla prior anti treatment therapy including durvalumab previous +Cluster 257: blasts marrow bone leukemia aml blood mds peripheral refractory patients +Cluster 258: cardiovascular significant disease clinically uncontrolled history including evidence pulmonary condition +Cluster 259: traumatic injury major procedure significant surgical open biopsy days study +Cluster 260: prostate cancer adenocarcinoma prior biopsy therapy diagnosis treatment prostatectomy chemotherapy +Cluster 261: replacement systemic modifying thyroxine pituitary disease autoimmune insulin physiologic adrenal +Cluster 262: surgical procedure resection major prior days study weeks biopsy patients +Cluster 263: syndrome myelodysplastic history poems malabsorption organomegaly endocrinopathy polyneuropathy gilbert changes +Cluster 264: severe infection immunodeficiency disease moderate pneumonia bacteremia hospitalization impairment complications +Cluster 265: metastatic disease evidence patients distant prior chemotherapy therapy recurrent cancer +Cluster 266: provide consent informed written able willing trial assent ability patients +Cluster 267: host graft gvhd versus disease transplant active stem allogeneic acute +Cluster 268: wort st phenytoin carbamazepine phenobarbital cypa rifampin johns inducers rifabutin +Cluster 269: kg body weight area surface bsa cells cd weigh patients +Cluster 270: ms qt interval corrected qtc qtcf fridericia mean correction ecg +Cluster 271: use medications prohibited medication drugs taking current study prior concomitant +Cluster 272: ventricular heart arrhythmias fibrillation uncontrolled history myocardial block infarction failure +Cluster 273: zubrod performance status patients registration days prior step ps karnofsky +Cluster 274: patient study subjects prior diagnosis participants subject clinical known blood +Cluster 275: birth control potential effective use study method agree childbearing women +Cluster 276: start treatment prior study weeks days trial investigational therapy radiotherapy +Cluster 277: hcg chorionic gonadotropin beta human test pregnancy negative women potential +Cluster 278: neck head radiation squamous carcinoma cancer cell prior therapy cavity +Cluster 279: physical examination activity history registration compulsorily detained days prior exam +Cluster 280: immunosuppressive systemic corticosteroids medications therapy treatment chronic use medication agents +Cluster 281: creatinine gault cockcroft clearance min ml formula calculated using equation +Cluster 282: access venous internet computer telephone central placement phone adequate sampling +Cluster 283: bilateral hysterectomy oophorectomy potential consecutive postmenopausal months childbearing tubal undergone +Cluster 284: leukocytes mcl ul mm microliter days registration obtained ml phase +Cluster 285: swallow oral retain able medication ability pills medications orally bowels +Cluster 286: finding metabolic reasonable suspicion contraindicates examination render dysfunction physical giving +Cluster 287: testosterone ng dl castrate serum level nmol levels castration androgen +Cluster 288: mother breastfeeding discontinued pregnant excluded women treated study agents potential +Cluster 289: coagulopathy bleeding diathesis evidence history anticoagulation significant therapeutic absence disorder +Cluster 290: requirements comply able study protocol adhere schedule visit monitoring safety +Cluster 291: anti pd ctla antibody prior therapy received checkpoint targeting agent +Cluster 292: ul neutrophil absolute count anc cells days peripheral registration prior +Cluster 293: hg pressure mm blood systolic hypertension diastolic uncontrolled bp despite +Cluster 294: lipase amylase uln serum pancreatitis radiologic normal clinical pancreatic evidence +Cluster 295: allergic reactions reaction history anaphylactic severe hypersensitivity humanized proteins antibodies +Cluster 296: transplantation allogeneic stem organ cell prior solid autologous hematopoietic marrow +Cluster 297: warfarin anticoagulation vitamin antagonists therapeutic use patients receiving concomitant requires +Cluster 298: pleural ascites effusion effusions pericardial requiring paracentesis drainage clinically thoracentesis +Cluster 299: heart york association new failure class congestive nyha iv iii