{
"criteria": {
"volunteer health status": {
"criterion": "volunteer health status",
"requirements": {
"status": {
"requirement_type": "status",
"groups": {
"healthy": {
"expected_value": "healthy",
"trial_ids": [
"NCT00001073",
"NCT00001120",
"NCT00001148",
"NCT00001272",
"NCT00001582",
"NCT00001748",
"NCT00002262",
"NCT00002476",
"NCT00002620",
"NCT00002631"
],
"truth_value": "false"
}
}
}
}
},
"gender": {
"criterion": "gender",
"requirements": {
"expected gender": {
"requirement_type": "expected gender",
"groups": {
"female": {
"expected_value": "female",
"trial_ids": [
"NCT00001073"
],
"truth_value": "false"
}
}
},
"gender": {
"requirement_type": "gender",
"groups": {
"female": {
"expected_value": "female",
"trial_ids": [
"NCT00001073"
],
"truth_value": "false"
}
}
},
"presence": {
"requirement_type": "presence",
"groups": {
"['male', 'female']": {
"expected_value": [
"male",
"female"
],
"trial_ids": [
"NCT00001148"
],
"truth_value": "true"
}
}
},
"expected_value": {
"requirement_type": "expected_value",
"groups": {
"female": {
"expected_value": "female",
"trial_ids": [
"NCT00001272"
],
"truth_value": "false"
},
"male": {
"expected_value": "male",
"trial_ids": [
"NCT00002262"
],
"truth_value": "true"
}
}
}
}
},
"age": {
"criterion": "age",
"requirements": {
"minimum": {
"requirement_type": "minimum",
"groups": {
"operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=13 unit='Years'": {
"expected_value": {
"operator": ">=",
"value": 13,
"unit": "Years"
},
"trial_ids": [
"NCT00001073"
],
"truth_value": "true"
},
"operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=18 unit='Years'": {
"expected_value": {
"operator": ">=",
"value": 18,
"unit": "Years"
},
"trial_ids": [
"NCT00001120",
"NCT00001582",
"NCT00002262",
"NCT00002476",
"NCT00002631"
],
"truth_value": "false"
},
"operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=16 unit='Years'": {
"expected_value": {
"operator": ">=",
"value": 16,
"unit": "Years"
},
"trial_ids": [
"NCT00002620"
],
"truth_value": "false"
}
}
},
"minimum age": {
"requirement_type": "minimum age",
"groups": {
"operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=13 unit='years'": {
"expected_value": {
"operator": ">=",
"value": 13,
"unit": "years"
},
"trial_ids": [
"NCT00001073"
],
"truth_value": "true"
},
"operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=18 unit='years'": {
"expected_value": {
"operator": ">=",
"value": 18,
"unit": "years"
},
"trial_ids": [
"NCT00001120"
],
"truth_value": "false"
},
"operator=<LLMOperator.GREATER_THAN: '>'> value=18 unit='years'": {
"expected_value": {
"operator": ">",
"value": 18,
"unit": "years"
},
"trial_ids": [
"NCT00001748"
],
"truth_value": "false"
},
"operator=<LLMOperator.GREATER_THAN: '>'> value=16 unit='years'": {
"expected_value": {
"operator": ">",
"value": 16,
"unit": "years"
},
"trial_ids": [
"NCT00002620"
],
"truth_value": "false"
}
}
},
"range": {
"requirement_type": "range",
"groups": {
"comparisons=[LLMNumericalComparison(operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='>, value=18, unit='years'), LLMNumericalComparison(operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='>, value=75, unit='years')]": {
"expected_value": {
"comparisons": [
{
"operator": ">=",
"value": 18,
"unit": "years"
},
{
"operator": "<=",
"value": 75,
"unit": "years"
}
]
},
"trial_ids": [
"NCT00001148"
],
"truth_value": "false"
},
"comparisons=[LLMNumericalComparison(operator=<LLMOperator.LESS_THAN: '<'>, value=18, unit='years')]": {
"expected_value": {
"comparisons": [
{
"operator": "<",
"value": 18,
"unit": "years"
}
]
},
"trial_ids": [
"NCT00001582"
],
"truth_value": "true"
},
"comparisons=[LLMNumericalComparison(operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='>, value=10, unit='years'), LLMNumericalComparison(operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='>, value=45, unit='years')]": {
"expected_value": {
"comparisons": [
{
"operator": ">=",
"value": 10,
"unit": "years"
},
{
"operator": "<=",
"value": 45,
"unit": "years"
}
]
},
"trial_ids": [
"NCT00001748"
],
"truth_value": "true"
}
}
},
"value": {
"requirement_type": "value",
"groups": {
"operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=18 unit='years'": {
"expected_value": {
"operator": ">=",
"value": 18,
"unit": "years"
},
"trial_ids": [
"NCT00001582"
],
"truth_value": "false"
}
}
},
"maximum": {
"requirement_type": "maximum",
"groups": {
"operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=70 unit='Years'": {
"expected_value": {
"operator": "<=",
"value": 70,
"unit": "Years"
},
"trial_ids": [
"NCT00002262"
],
"truth_value": "true"
}
}
},
"maximum age": {
"requirement_type": "maximum age",
"groups": {
"operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=75 unit='years'": {
"expected_value": {
"operator": "<=",
"value": 75,
"unit": "years"
},
"trial_ids": [
"NCT00002476"
],
"truth_value": "true"
}
}
}
}
},
"hiv status": {
"criterion": "hiv status",
"requirements": {
"status": {
"requirement_type": "status",
"groups": {
"positive": {
"expected_value": "positive",
"trial_ids": [
"NCT00001073",
"NCT00001120",
"NCT00001148"
],
"truth_value": "unknown"
},
"negative": {
"expected_value": "negative",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"parental consent": {
"criterion": "parental consent",
"requirements": {
"requirement": {
"requirement_type": "requirement",
"groups": {
"required if under 18": {
"expected_value": "required if under 18",
"trial_ids": [
"NCT00001073"
],
"truth_value": "unknown"
}
}
}
}
},
"cervical tumors": {
"criterion": "cervical tumors",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001073"
],
"truth_value": "unknown"
}
}
},
"determination method": {
"requirement_type": "determination method",
"groups": {
"biopsy": {
"expected_value": "biopsy",
"trial_ids": [
"NCT00001073"
],
"truth_value": "unknown"
}
}
}
}
},
"contraceptive use": {
"criterion": "contraceptive use",
"requirements": {
"methods": {
"requirement_type": "methods",
"groups": {
"['condoms', 'the pill']": {
"expected_value": [
"condoms",
"the pill"
],
"trial_ids": [
"NCT00001073"
],
"truth_value": "unknown"
}
}
}
}
},
"cancer therapies": {
"criterion": "cancer therapies",
"requirements": {
"recency": {
"requirement_type": "recency",
"groups": {
"comparisons=[LLMNumericalComparison(operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='>, value=4, unit='months')]": {
"expected_value": {
"comparisons": [
{
"operator": "<=",
"value": 4,
"unit": "months"
}
]
},
"trial_ids": [
"NCT00001073"
],
"truth_value": "unknown"
}
}
}
}
},
"hysterectomy": {
"criterion": "hysterectomy",
"requirements": {
"time since procedure": {
"requirement_type": "time since procedure",
"groups": {
"operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=4 unit='months'": {
"expected_value": {
"operator": "<=",
"value": 4,
"unit": "months"
},
"trial_ids": [
"NCT00001073"
],
"truth_value": "unknown"
}
}
}
}
},
"tetracycline usage": {
"criterion": "tetracycline usage",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001073"
],
"truth_value": "unknown"
}
}
}
}
},
"vitamin a usage": {
"criterion": "vitamin a usage",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001073"
],
"truth_value": "unknown"
}
}
}
}
},
"medication history": {
"criterion": "medication history",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001073"
],
"truth_value": "unknown"
}
}
}
}
},
"anti-hiv drugs and medications to prevent aids-related opportunistic infections": {
"criterion": "anti-hiv drugs and medications to prevent aids-related opportunistic infections",
"requirements": {
"approval": {
"requirement_type": "approval",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001073"
],
"truth_value": "unknown"
}
}
}
}
},
"pregnancy": {
"criterion": "pregnancy",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001073"
],
"truth_value": "unknown"
},
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"cd4+ cell count": {
"criterion": "cd4+ cell count",
"requirements": {
"quantity": {
"requirement_type": "quantity",
"groups": {
"operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=200 unit='cells/mm3'": {
"expected_value": {
"operator": "<=",
"value": 200,
"unit": "cells/mm3"
},
"trial_ids": [
"NCT00001120"
],
"truth_value": "unknown"
}
}
}
}
},
"follow-up availability": {
"criterion": "follow-up availability",
"requirements": {
"duration": {
"requirement_type": "duration",
"groups": {
"operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=3 unit='years'": {
"expected_value": {
"operator": ">=",
"value": 3,
"unit": "years"
},
"trial_ids": [
"NCT00001120"
],
"truth_value": "unknown"
}
}
}
}
},
"glioblastoma multiforme": {
"criterion": "glioblastoma multiforme",
"requirements": {
"diagnosis": {
"requirement_type": "diagnosis",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
},
"confirmation method": {
"requirement_type": "confirmation method",
"groups": {
"biopsy-proven": {
"expected_value": "biopsy-proven",
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"anaplastic astrocytoma": {
"criterion": "anaplastic astrocytoma",
"requirements": {
"diagnosis": {
"requirement_type": "diagnosis",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
},
"confirmation method": {
"requirement_type": "confirmation method",
"groups": {
"biopsy-proven": {
"expected_value": "biopsy-proven",
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
},
"confirmation": {
"requirement_type": "confirmation",
"groups": {
"histologically confirmed": {
"expected_value": "histologically confirmed",
"trial_ids": [
"NCT00002620"
],
"truth_value": "unknown"
}
}
}
}
},
"who grade": {
"criterion": "who grade",
"requirements": {
"classification": {
"requirement_type": "classification",
"groups": {
"['III', 'IV']": {
"expected_value": [
"III",
"IV"
],
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"informed consent": {
"criterion": "informed consent",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001148",
"NCT00001748"
],
"truth_value": "unknown"
}
}
},
"ability": {
"requirement_type": "ability",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
},
"given": {
"requirement_type": "given",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"karnofsky performance scale score": {
"criterion": "karnofsky performance scale score",
"requirements": {
"value": {
"requirement_type": "value",
"groups": {
"operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=60 unit='N/A'": {
"expected_value": {
"operator": ">=",
"value": 60,
"unit": "N/A"
},
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
},
"operator=<LLMOperator.LESS_THAN: '<'> value=60 unit='N/A'": {
"expected_value": {
"operator": "<",
"value": 60,
"unit": "N/A"
},
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"race": {
"criterion": "race",
"requirements": {
"eligibility": {
"requirement_type": "eligibility",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"sex": {
"criterion": "sex",
"requirements": {
"eligibility": {
"requirement_type": "eligibility",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"age group": {
"criterion": "age group",
"requirements": {
"eligibility": {
"requirement_type": "eligibility",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"acceptance for glioma resection": {
"criterion": "acceptance for glioma resection",
"requirements": {
"protocol": {
"requirement_type": "protocol",
"groups": {
"existing NINDS protocols": {
"expected_value": "existing NINDS protocols",
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"tumor tissue": {
"criterion": "tumor tissue",
"requirements": {
"availability": {
"requirement_type": "availability",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"tumor-specific mutation(s)": {
"criterion": "tumor-specific mutation(s)",
"requirements": {
"identification": {
"requirement_type": "identification",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"clinical stability": {
"criterion": "clinical stability",
"requirements": {
"stability": {
"requirement_type": "stability",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"total bilirubin": {
"criterion": "total bilirubin",
"requirements": {
"level": {
"requirement_type": "level",
"groups": {
"operator=<LLMOperator.GREATER_THAN: '>'> value=2.0 unit='mg/dl'": {
"expected_value": {
"operator": ">",
"value": 2.0,
"unit": "mg/dl"
},
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"ast or alt": {
"criterion": "ast or alt",
"requirements": {
"level": {
"requirement_type": "level",
"groups": {
"greater than 3 times the upper limit of normal": {
"expected_value": "greater than 3 times the upper limit of normal",
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"prothrombin time (pt)": {
"criterion": "prothrombin time (pt)",
"requirements": {
"comparison": {
"requirement_type": "comparison",
"groups": {
"operator=<LLMOperator.GREATER_THAN: '>'> value=1.5 unit='times control'": {
"expected_value": {
"operator": ">",
"value": 1.5,
"unit": "times control"
},
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"activated partial thromboplastin time (aptt)": {
"criterion": "activated partial thromboplastin time (aptt)",
"requirements": {
"comparison": {
"requirement_type": "comparison",
"groups": {
"operator=<LLMOperator.GREATER_THAN: '>'> value=1.5 unit='times control'": {
"expected_value": {
"operator": ">",
"value": 1.5,
"unit": "times control"
},
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"platelet count": {
"criterion": "platelet count",
"requirements": {
"quantity": {
"requirement_type": "quantity",
"groups": {
"operator=<LLMOperator.LESS_THAN: '<'> value=100000 unit='mm3'": {
"expected_value": {
"operator": "<",
"value": 100000,
"unit": "mm3"
},
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
},
"operator=<LLMOperator.GREATER_THAN: '>'> value=100000 unit='N/A'": {
"expected_value": {
"operator": ">",
"value": 100000,
"unit": "N/A"
},
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
},
"level": {
"requirement_type": "level",
"groups": {
"operator=<LLMOperator.GREATER_THAN: '>'> value=50000 unit='N/A'": {
"expected_value": {
"operator": ">",
"value": 50000,
"unit": "N/A"
},
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
},
"minimum count": {
"requirement_type": "minimum count",
"groups": {
"operator=<LLMOperator.GREATER_THAN: '>'> value=100000 unit='N/A'": {
"expected_value": {
"operator": ">",
"value": 100000,
"unit": "N/A"
},
"trial_ids": [
"NCT00002620"
],
"truth_value": "unknown"
}
}
}
}
},
"absolute neutrophil count": {
"criterion": "absolute neutrophil count",
"requirements": {
"quantity": {
"requirement_type": "quantity",
"groups": {
"operator=<LLMOperator.LESS_THAN: '<'> value=1000 unit='mm3'": {
"expected_value": {
"operator": "<",
"value": 1000,
"unit": "mm3"
},
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"acute infection": {
"criterion": "acute infection",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"acute medical problems": {
"criterion": "acute medical problems",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"allergy": {
"criterion": "allergy",
"requirements": {
"substance": {
"requirement_type": "substance",
"groups": {
"CT contrast agents": {
"expected_value": "CT contrast agents",
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"tumor-specific gene mutation": {
"criterion": "tumor-specific gene mutation",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001148"
],
"truth_value": "unknown"
}
}
}
}
},
"ovarian cancer": {
"criterion": "ovarian cancer",
"requirements": {
"confirmation method": {
"requirement_type": "confirmation method",
"groups": {
"biopsy proven": {
"expected_value": "biopsy proven",
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"evaluation location": {
"criterion": "evaluation location",
"requirements": {
"location": {
"requirement_type": "location",
"groups": {
"Laboratory of Pathology, NCI": {
"expected_value": "Laboratory of Pathology, NCI",
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"germ cell histology": {
"criterion": "germ cell histology",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"borderline histology": {
"criterion": "borderline histology",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"figo stage": {
"criterion": "figo stage",
"requirements": {
"stage": {
"requirement_type": "stage",
"groups": {
"['III', 'IV']": {
"expected_value": [
"III",
"IV"
],
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
},
"IIC": {
"expected_value": "IIC",
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
},
"histology differentiation": {
"requirement_type": "histology differentiation",
"groups": {
"poorly differentiated": {
"expected_value": "poorly differentiated",
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"surgical debulking": {
"criterion": "surgical debulking",
"requirements": {
"procedure": {
"requirement_type": "procedure",
"groups": {
"attempted": {
"expected_value": "attempted",
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"performance status": {
"criterion": "performance status",
"requirements": {
"severity": {
"requirement_type": "severity",
"groups": {
"operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=2 unit='ECOG'": {
"expected_value": {
"operator": "<=",
"value": 2,
"unit": "ECOG"
},
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
},
"scale": {
"requirement_type": "scale",
"groups": {
"['ECOG', 'ZUBROD', 'WHO']": {
"expected_value": [
"ECOG",
"ZUBROD",
"WHO"
],
"trial_ids": [
"NCT00002620"
],
"truth_value": "unknown"
}
}
},
"range": {
"requirement_type": "range",
"groups": {
"comparisons=[LLMNumericalComparison(operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='>, value=0, unit='N/A'), LLMNumericalComparison(operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='>, value=2, unit='N/A')]": {
"expected_value": {
"comparisons": [
{
"operator": ">=",
"value": 0,
"unit": "N/A"
},
{
"operator": "<=",
"value": 2,
"unit": "N/A"
}
]
},
"trial_ids": [
"NCT00002620"
],
"truth_value": "unknown"
}
}
}
}
},
"end organ function": {
"criterion": "end organ function",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"brain involvement": {
"criterion": "brain involvement",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"myocardial infarction": {
"criterion": "myocardial infarction",
"requirements": {
"history": {
"requirement_type": "history",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"cardiac arrhythmias": {
"criterion": "cardiac arrhythmias",
"requirements": {
"treatment": {
"requirement_type": "treatment",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"right bundle branch block": {
"criterion": "right bundle branch block",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"left anterior hemiblock": {
"criterion": "left anterior hemiblock",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"left bundle branch block": {
"criterion": "left bundle branch block",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"creatinine clearance": {
"criterion": "creatinine clearance",
"requirements": {
"quantity": {
"requirement_type": "quantity",
"groups": {
"operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=60 unit='cc/min'": {
"expected_value": {
"operator": ">=",
"value": 60,
"unit": "cc/min"
},
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
},
"minimum clearance": {
"requirement_type": "minimum clearance",
"groups": {
"operator=<LLMOperator.GREATER_THAN: '>'> value=70 unit='ml/min'": {
"expected_value": {
"operator": ">",
"value": 70,
"unit": "ml/min"
},
"trial_ids": [
"NCT00002620"
],
"truth_value": "unknown"
}
}
}
}
},
"ureteral obstruction": {
"criterion": "ureteral obstruction",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"hepatic function": {
"criterion": "hepatic function",
"requirements": {
"coagulation parameters": {
"requirement_type": "coagulation parameters",
"groups": {
"normal": {
"expected_value": "normal",
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"serum transaminases": {
"criterion": "serum transaminases",
"requirements": {
"level": {
"requirement_type": "level",
"groups": {
"operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=3 unit='times upper limit of normal'": {
"expected_value": {
"operator": "<=",
"value": 3,
"unit": "times upper limit of normal"
},
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"neurologic function": {
"criterion": "neurologic function",
"requirements": {
"severity": {
"requirement_type": "severity",
"groups": {
"operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=1 unit='grade'": {
"expected_value": {
"operator": "<=",
"value": 1,
"unit": "grade"
},
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"active gi bleeding": {
"criterion": "active gi bleeding",
"requirements": {
"history": {
"requirement_type": "history",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"total granulocyte count": {
"criterion": "total granulocyte count",
"requirements": {
"quantity": {
"requirement_type": "quantity",
"groups": {
"operator=<LLMOperator.GREATER_THAN: '>'> value=2000 unit='N/A'": {
"expected_value": {
"operator": ">",
"value": 2000,
"unit": "N/A"
},
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"prior history of invasive malignancy": {
"criterion": "prior history of invasive malignancy",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"nonmelanoma skin cancer": {
"criterion": "nonmelanoma skin cancer",
"requirements": {
"treatment status": {
"requirement_type": "treatment status",
"groups": {
"curatively treated": {
"expected_value": "curatively treated",
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"willingness to meet protocol requirements": {
"criterion": "willingness to meet protocol requirements",
"requirements": {
"willingness": {
"requirement_type": "willingness",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"therapy initiation time": {
"criterion": "therapy initiation time",
"requirements": {
"time frame": {
"requirement_type": "time frame",
"groups": {
"operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=8 unit='weeks'": {
"expected_value": {
"operator": "<=",
"value": 8,
"unit": "weeks"
},
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"central venous catheter": {
"criterion": "central venous catheter",
"requirements": {
"placement": {
"requirement_type": "placement",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"registration": {
"criterion": "registration",
"requirements": {
"method": {
"requirement_type": "method",
"groups": {
"calling": {
"expected_value": "calling",
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
},
"contact": {
"requirement_type": "contact",
"groups": {
"Orkand Corporation at 402-1732": {
"expected_value": "Orkand Corporation at 402-1732",
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
},
"time": {
"requirement_type": "time",
"groups": {
"comparisons=[LLMNumericalComparison(operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='>, value=8.5, unit='hours'), LLMNumericalComparison(operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='>, value=17, unit='hours')]": {
"expected_value": {
"comparisons": [
{
"operator": ">=",
"value": 8.5,
"unit": "hours"
},
{
"operator": "<=",
"value": 17,
"unit": "hours"
}
]
},
"trial_ids": [
"NCT00001272"
],
"truth_value": "unknown"
}
}
}
}
},
"medical condition": {
"criterion": "medical condition",
"requirements": {
"worsened by apheresis": {
"requirement_type": "worsened by apheresis",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"congestive heart failure": {
"criterion": "congestive heart failure",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"angina": {
"criterion": "angina",
"requirements": {
"history": {
"requirement_type": "history",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"hypotension": {
"criterion": "hypotension",
"requirements": {
"severity": {
"requirement_type": "severity",
"groups": {
"severe": {
"expected_value": "severe",
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"hypertension": {
"criterion": "hypertension",
"requirements": {
"control": {
"requirement_type": "control",
"groups": {
"poorly controlled": {
"expected_value": "poorly controlled",
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"blood pressure": {
"criterion": "blood pressure",
"requirements": {
"average baseline": {
"requirement_type": "average baseline",
"groups": {
"comparisons=[LLMNumericalComparison(operator=<LLMOperator.GREATER_THAN: '>'>, value=160, unit='mmHg'), LLMNumericalComparison(operator=<LLMOperator.GREATER_THAN: '>'>, value=90, unit='mmHg')]": {
"expected_value": {
"comparisons": [
{
"operator": ">",
"value": 160,
"unit": "mmHg"
},
{
"operator": ">",
"value": 90,
"unit": "mmHg"
}
]
},
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
},
"status": {
"requirement_type": "status",
"groups": {
"normotensive": {
"expected_value": "normotensive",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"coagulation protein disorder": {
"criterion": "coagulation protein disorder",
"requirements": {
"history": {
"requirement_type": "history",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"apheresis": {
"criterion": "apheresis",
"requirements": {
"eligibility": {
"requirement_type": "eligibility",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
},
"desire": {
"requirement_type": "desire",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
},
"necessity": {
"requirement_type": "necessity",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"disorder of the immune system": {
"criterion": "disorder of the immune system",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"cancer": {
"criterion": "cancer",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"autoimmune disorder": {
"criterion": "autoimmune disorder",
"requirements": {
"carrier status": {
"requirement_type": "carrier status",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"immunodeficiency disease": {
"criterion": "immunodeficiency disease",
"requirements": {
"carrier status": {
"requirement_type": "carrier status",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"x-linked severe combined immunodeficiency": {
"criterion": "x-linked severe combined immunodeficiency",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"scid": {
"criterion": "scid",
"requirements": {
"inheritance pattern": {
"requirement_type": "inheritance pattern",
"groups": {
"autosomal recessive": {
"expected_value": "autosomal recessive",
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"x-linked cd40 ligand deficiency": {
"criterion": "x-linked cd40 ligand deficiency",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"common variable immunodeficiency": {
"criterion": "common variable immunodeficiency",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"ataxia-telangiectasia": {
"criterion": "ataxia-telangiectasia",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"wiskott aldrich syndrome": {
"criterion": "wiskott aldrich syndrome",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"digeorge syndrome": {
"criterion": "digeorge syndrome",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"htlv-1 infection": {
"criterion": "htlv-1 infection",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"understanding ability": {
"criterion": "understanding ability",
"requirements": {
"ability": {
"requirement_type": "ability",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"informed consent signing": {
"criterion": "informed consent signing",
"requirements": {
"ability": {
"requirement_type": "ability",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"hematocrit": {
"criterion": "hematocrit",
"requirements": {
"level": {
"requirement_type": "level",
"groups": {
"operator=<LLMOperator.GREATER_THAN: '>'> value=28 unit='%'": {
"expected_value": {
"operator": ">",
"value": 28,
"unit": "%"
},
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
},
"minimum percentage": {
"requirement_type": "minimum percentage",
"groups": {
"operator=<LLMOperator.GREATER_THAN: '>'> value=30 unit='%'": {
"expected_value": {
"operator": ">",
"value": 30,
"unit": "%"
},
"trial_ids": [
"NCT00002620"
],
"truth_value": "unknown"
}
}
}
}
},
"counts": {
"criterion": "counts",
"requirements": {
"comparison": {
"requirement_type": "comparison",
"groups": {
"lower than those above": {
"expected_value": "lower than those above",
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"weight": {
"criterion": "weight",
"requirements": {
"quantity": {
"requirement_type": "quantity",
"groups": {
"operator=<LLMOperator.GREATER_THAN: '>'> value=25 unit='kg'": {
"expected_value": {
"operator": ">",
"value": 25,
"unit": "kg"
},
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"overall health": {
"criterion": "overall health",
"requirements": {
"status": {
"requirement_type": "status",
"groups": {
"N/A": {
"expected_value": "N/A",
"trial_ids": [
"NCT00001582"
],
"truth_value": "unknown"
}
}
}
}
},
"chronic myelogenous leukemia": {
"criterion": "chronic myelogenous leukemia",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"leukemia phase": {
"criterion": "leukemia phase",
"requirements": {
"category": {
"requirement_type": "category",
"groups": {
"accelerated phase": {
"expected_value": "accelerated phase",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
},
"blast transformation": {
"expected_value": "blast transformation",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"acute lymphoblastic leukemia": {
"criterion": "acute lymphoblastic leukemia",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"remission status": {
"criterion": "remission status",
"requirements": {
"status": {
"requirement_type": "status",
"groups": {
"any remission": {
"expected_value": "any remission",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"high-risk features": {
"criterion": "high-risk features",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"leukocyte count": {
"criterion": "leukocyte count",
"requirements": {
"count": {
"requirement_type": "count",
"groups": {
"operator=<LLMOperator.GREATER_THAN: '>'> value=100000 unit='cu mm'": {
"expected_value": {
"operator": ">",
"value": 100000,
"unit": "cu mm"
},
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"karyotypes": {
"criterion": "karyotypes",
"requirements": {
"specific karyotypes": {
"requirement_type": "specific karyotypes",
"groups": {
"['t9; 22', 't4', 't19', 't11']": {
"expected_value": [
"t9; 22",
"t4",
"t19",
"t11"
],
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"biphenotypic leukemia": {
"criterion": "biphenotypic leukemia",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"second remission": {
"criterion": "second remission",
"requirements": {
"status": {
"requirement_type": "status",
"groups": {
"all": {
"expected_value": "all",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"primary induction failure": {
"criterion": "primary induction failure",
"requirements": {
"status": {
"requirement_type": "status",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"partial remission": {
"criterion": "partial remission",
"requirements": {
"status": {
"requirement_type": "status",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"response status": {
"criterion": "response status",
"requirements": {
"status": {
"requirement_type": "status",
"groups": {
"partially responding": {
"expected_value": "partially responding",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"untreated relapse": {
"criterion": "untreated relapse",
"requirements": {
"status": {
"requirement_type": "status",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"acute myelogenous leukemia (aml)": {
"criterion": "acute myelogenous leukemia (aml)",
"requirements": {
"condition": {
"requirement_type": "condition",
"groups": {
"second or subsequent remission": {
"expected_value": "second or subsequent remission",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
},
"primary induction failure": {
"expected_value": "primary induction failure",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
},
"partial remission": {
"expected_value": "partial remission",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
},
"resistant relapse": {
"expected_value": "resistant relapse",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"myelodysplastic syndromes": {
"criterion": "myelodysplastic syndromes",
"requirements": {
"categories": {
"requirement_type": "categories",
"groups": {
"['refractory anemia with excess of blasts']": {
"expected_value": [
"refractory anemia with excess of blasts"
],
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
},
"['transformation to acute leukemia']": {
"expected_value": [
"transformation to acute leukemia"
],
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
},
"['chronic myelomonocytic leukemia']": {
"expected_value": [
"chronic myelomonocytic leukemia"
],
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"myeloproliferative disorders": {
"criterion": "myeloproliferative disorders",
"requirements": {
"transformation stage": {
"requirement_type": "transformation stage",
"groups": {
"terminal": {
"expected_value": "terminal",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"chronic lymphocytic leukemia": {
"criterion": "chronic lymphocytic leukemia",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"richter transformation": {
"criterion": "richter transformation",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"lymphoma": {
"criterion": "lymphoma",
"requirements": {
"grade": {
"requirement_type": "grade",
"groups": {
"high": {
"expected_value": "high",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"treatment response": {
"criterion": "treatment response",
"requirements": {
"response": {
"requirement_type": "response",
"groups": {
"refractory": {
"expected_value": "refractory",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"lymphoma subtype": {
"criterion": "lymphoma subtype",
"requirements": {
"subtype": {
"requirement_type": "subtype",
"groups": {
"mantle cell": {
"expected_value": "mantle cell",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"major organ dysfunction": {
"criterion": "major organ dysfunction",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"transplantation": {
"criterion": "transplantation",
"requirements": {
"preclusion": {
"requirement_type": "preclusion",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"dlco": {
"criterion": "dlco",
"requirements": {
"value": {
"requirement_type": "value",
"groups": {
"operator=<LLMOperator.GREATER_THAN: '>'> value=65 unit='% predicted'": {
"expected_value": {
"operator": ">",
"value": 65,
"unit": "% predicted"
},
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
},
"predicted percentage": {
"requirement_type": "predicted percentage",
"groups": {
"operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=65 unit='%'": {
"expected_value": {
"operator": ">=",
"value": 65,
"unit": "%"
},
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"left ventricular ejection fraction": {
"criterion": "left ventricular ejection fraction",
"requirements": {
"value": {
"requirement_type": "value",
"groups": {
"operator=<LLMOperator.GREATER_THAN: '>'> value=40 unit='%'": {
"expected_value": {
"operator": ">",
"value": 40,
"unit": "%"
},
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
},
"operator=<LLMOperator.LESS_THAN: '<'> value=40 unit='%'": {
"expected_value": {
"operator": "<",
"value": 40,
"unit": "%"
},
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"ecog performance status": {
"criterion": "ecog performance status",
"requirements": {
"value": {
"requirement_type": "value",
"groups": {
"['0', '1']": {
"expected_value": [
"0",
"1"
],
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
},
"severity": {
"requirement_type": "severity",
"groups": {
"operator=<LLMOperator.LESS_THAN: '<'> value=2 unit='N/A'": {
"expected_value": {
"operator": "<",
"value": 2,
"unit": "N/A"
},
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"informed consent from parents": {
"criterion": "informed consent from parents",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"gender and reproductive status": {
"criterion": "gender and reproductive status",
"requirements": {
"gender": {
"requirement_type": "gender",
"groups": {
"female": {
"expected_value": "female",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
},
"reproductive status": {
"requirement_type": "reproductive status",
"groups": {
"childbearing age": {
"expected_value": "childbearing age",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"pregnancy test result": {
"criterion": "pregnancy test result",
"requirements": {
"result": {
"requirement_type": "result",
"groups": {
"negative": {
"expected_value": "negative",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"donor": {
"criterion": "donor",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"hla match with family donor": {
"criterion": "hla match with family donor",
"requirements": {
"match level": {
"requirement_type": "match level",
"groups": {
"comparisons=[LLMNumericalComparison(operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='>, value=3, unit='matches'), LLMNumericalComparison(operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='>, value=5, unit='matches')]": {
"expected_value": {
"comparisons": [
{
"operator": ">=",
"value": 3,
"unit": "matches"
},
{
"operator": "<=",
"value": 5,
"unit": "matches"
}
]
},
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"g-csf administration": {
"criterion": "g-csf administration",
"requirements": {
"fitness": {
"requirement_type": "fitness",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"peripheral blood stem cell donation": {
"criterion": "peripheral blood stem cell donation",
"requirements": {
"fitness": {
"requirement_type": "fitness",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"blood count": {
"criterion": "blood count",
"requirements": {
"status": {
"requirement_type": "status",
"groups": {
"normal": {
"expected_value": "normal",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"history of stroke": {
"criterion": "history of stroke",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"pregnancy status": {
"criterion": "pregnancy status",
"requirements": {
"status": {
"requirement_type": "status",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"nursing status": {
"criterion": "nursing status",
"requirements": {
"status": {
"requirement_type": "status",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"psychiatric illness": {
"criterion": "psychiatric illness",
"requirements": {
"severity": {
"requirement_type": "severity",
"groups": {
"not severe": {
"expected_value": "not severe",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"psychiatric illness in donor": {
"criterion": "psychiatric illness in donor",
"requirements": {
"severity": {
"requirement_type": "severity",
"groups": {
"not severe": {
"expected_value": "not severe",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"mental deficiency": {
"criterion": "mental deficiency",
"requirements": {
"severity": {
"requirement_type": "severity",
"groups": {
"sufficiently severe to make compliance with the BMT treatment unlikely": {
"expected_value": "sufficiently severe to make compliance with the BMT treatment unlikely",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
},
"making informed consent impossible": {
"expected_value": "making informed consent impossible",
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"major anticipated illness": {
"criterion": "major anticipated illness",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"organ failure incompatible with survival from bmt": {
"criterion": "organ failure incompatible with survival from bmt",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"serum creatinine": {
"criterion": "serum creatinine",
"requirements": {
"level": {
"requirement_type": "level",
"groups": {
"operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=3 unit='mg/dl'": {
"expected_value": {
"operator": "<=",
"value": 3,
"unit": "mg/dl"
},
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"serum bilirubin": {
"criterion": "serum bilirubin",
"requirements": {
"level": {
"requirement_type": "level",
"groups": {
"operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=4 unit='mg/dl'": {
"expected_value": {
"operator": "<=",
"value": 4,
"unit": "mg/dl"
},
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"transaminases": {
"criterion": "transaminases",
"requirements": {
"level": {
"requirement_type": "level",
"groups": {
"operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=3 unit='times the upper limit of normal'": {
"expected_value": {
"operator": "<=",
"value": 3,
"unit": "times the upper limit of normal"
},
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"history of other malignancies": {
"criterion": "history of other malignancies",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"basal cell or squamous carcinoma of the skin": {
"criterion": "basal cell or squamous carcinoma of the skin",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"positive pap smear": {
"criterion": "positive pap smear",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"negative follow up after positive pap smear": {
"criterion": "negative follow up after positive pap smear",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"fitness to receive g-csf": {
"criterion": "fitness to receive g-csf",
"requirements": {
"fitness": {
"requirement_type": "fitness",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"fitness to undergo apheresis": {
"criterion": "fitness to undergo apheresis",
"requirements": {
"fitness": {
"requirement_type": "fitness",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"cd34+ cell mobilization": {
"criterion": "cd34+ cell mobilization",
"requirements": {
"adequacy": {
"requirement_type": "adequacy",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"g-csf cycles": {
"criterion": "g-csf cycles",
"requirements": {
"quantity": {
"requirement_type": "quantity",
"groups": {
"operator=<LLMOperator.EQUAL_TO: '='> value=2 unit='cycles'": {
"expected_value": {
"operator": "=",
"value": 2,
"unit": "cycles"
},
"trial_ids": [
"NCT00001748"
],
"truth_value": "unknown"
}
}
}
}
},
"kaposi's sarcoma": {
"criterion": "kaposi's sarcoma",
"requirements": {
"diagnosis": {
"requirement_type": "diagnosis",
"groups": {
"biopsy-proven": {
"expected_value": "biopsy-proven",
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"cutaneous lesions": {
"criterion": "cutaneous lesions",
"requirements": {
"quantity": {
"requirement_type": "quantity",
"groups": {
"multiple": {
"expected_value": "multiple",
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"life expectancy": {
"criterion": "life expectancy",
"requirements": {
"duration": {
"requirement_type": "duration",
"groups": {
"operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=3 unit='months'": {
"expected_value": {
"operator": ">=",
"value": 3,
"unit": "months"
},
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
},
"minimum duration": {
"requirement_type": "minimum duration",
"groups": {
"operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=8 unit='weeks'": {
"expected_value": {
"operator": ">=",
"value": 8,
"unit": "weeks"
},
"trial_ids": [
"NCT00002620"
],
"truth_value": "unknown"
}
}
}
}
},
"co-existing condition": {
"criterion": "co-existing condition",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"cardiac disease": {
"criterion": "cardiac disease",
"requirements": {
"severity": {
"requirement_type": "severity",
"groups": {
"clinically significant": {
"expected_value": "clinically significant",
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"hemorrhagic diathesis": {
"criterion": "hemorrhagic diathesis",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"bleeding disorder": {
"criterion": "bleeding disorder",
"requirements": {
"activity": {
"requirement_type": "activity",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"vascular disease": {
"criterion": "vascular disease",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
},
"clinical appearance": {
"requirement_type": "clinical appearance",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"lipoprotein disorders": {
"criterion": "lipoprotein disorders",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"seizure disorder": {
"criterion": "seizure disorder",
"requirements": {
"history": {
"requirement_type": "history",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"cns metastasis": {
"criterion": "cns metastasis",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"additional malignancy": {
"criterion": "additional malignancy",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"concurrent medication": {
"criterion": "concurrent medication",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"cardiac agents": {
"criterion": "cardiac agents",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"anticoagulant use": {
"criterion": "anticoagulant use",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"thrombolytic agents": {
"criterion": "thrombolytic agents",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"nonsteroidal anti-inflammatory drugs": {
"criterion": "nonsteroidal anti-inflammatory drugs",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"corticosteroids": {
"criterion": "corticosteroids",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"aspirin": {
"criterion": "aspirin",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"vasodilator use": {
"criterion": "vasodilator use",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"additional malignancies": {
"criterion": "additional malignancies",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"other conditions listed in patient exclusion co-existing conditions": {
"criterion": "other conditions listed in patient exclusion co-existing conditions",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"prior treatment": {
"criterion": "prior treatment",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"time since exclusion": {
"criterion": "time since exclusion",
"requirements": {
"duration": {
"requirement_type": "duration",
"groups": {
"operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=4 unit='weeks'": {
"expected_value": {
"operator": "<=",
"value": 4,
"unit": "weeks"
},
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"chemotherapy": {
"criterion": "chemotherapy",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
},
"prior therapy": {
"requirement_type": "prior therapy",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
},
"prior treatment": {
"requirement_type": "prior treatment",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
}
}
},
"radiotherapy": {
"criterion": "radiotherapy",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
},
"prior therapy": {
"requirement_type": "prior therapy",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"immunotherapy": {
"criterion": "immunotherapy",
"requirements": {
"treatment": {
"requirement_type": "treatment",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002262"
],
"truth_value": "unknown"
}
}
}
}
},
"squamous cell cancer of the head and neck": {
"criterion": "squamous cell cancer of the head and neck",
"requirements": {
"confirmation": {
"requirement_type": "confirmation",
"groups": {
"histologically confirmed": {
"expected_value": "histologically confirmed",
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"suitability for treatment with radiotherapy": {
"criterion": "suitability for treatment with radiotherapy",
"requirements": {
"suitability": {
"requirement_type": "suitability",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"primary lesion stage": {
"criterion": "primary lesion stage",
"requirements": {
"stage": {
"requirement_type": "stage",
"groups": {
"['T2', 'T3', 'T4']": {
"expected_value": [
"T2",
"T3",
"T4"
],
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"nodal involvement": {
"criterion": "nodal involvement",
"requirements": {
"stage": {
"requirement_type": "stage",
"groups": {
"Any N": {
"expected_value": "Any N",
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"distant metastasis": {
"criterion": "distant metastasis",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"carcinoma type": {
"criterion": "carcinoma type",
"requirements": {
"type": {
"requirement_type": "type",
"groups": {
"['anaplastic carcinoma', 'verrucous carcinoma', 'transitional cell carcinoma']": {
"expected_value": [
"anaplastic carcinoma",
"verrucous carcinoma",
"transitional cell carcinoma"
],
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"occult primaries": {
"criterion": "occult primaries",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"cancer type exclusion": {
"criterion": "cancer type exclusion",
"requirements": {
"exclusion": {
"requirement_type": "exclusion",
"groups": {
"['adenocarcinomas', 'lymphomas', 'melanomas']": {
"expected_value": [
"adenocarcinomas",
"lymphomas",
"melanomas"
],
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"synchronous head and neck tumors": {
"criterion": "synchronous head and neck tumors",
"requirements": {
"eligibility": {
"requirement_type": "eligibility",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"surgery to neck nodes": {
"criterion": "surgery to neck nodes",
"requirements": {
"randomization": {
"requirement_type": "randomization",
"groups": {
"surgery patients": {
"expected_value": "surgery patients",
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"tumors of the oral cavity or oropharynx": {
"criterion": "tumors of the oral cavity or oropharynx",
"requirements": {
"randomization option": {
"requirement_type": "randomization option",
"groups": {
"nodal irradiation vs. no further therapy": {
"expected_value": "nodal irradiation vs. no further therapy",
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
},
"condition": {
"requirement_type": "condition",
"groups": {
"no second primary": {
"expected_value": "no second primary",
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"fitness for protocol treatment": {
"criterion": "fitness for protocol treatment",
"requirements": {
"fitness": {
"requirement_type": "fitness",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"willingness to receive protocol treatment": {
"criterion": "willingness to receive protocol treatment",
"requirements": {
"willingness": {
"requirement_type": "willingness",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"prior malignancy": {
"criterion": "prior malignancy",
"requirements": {
"cured status": {
"requirement_type": "cured status",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"biologic therapy": {
"criterion": "biologic therapy",
"requirements": {
"prior therapy": {
"requirement_type": "prior therapy",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"endocrine therapy": {
"criterion": "endocrine therapy",
"requirements": {
"prior therapy": {
"requirement_type": "prior therapy",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"surgery": {
"criterion": "surgery",
"requirements": {
"prior biopsy or excision": {
"requirement_type": "prior biopsy or excision",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002476"
],
"truth_value": "unknown"
}
}
}
}
},
"surgical procedure": {
"criterion": "surgical procedure",
"requirements": {
"type": {
"requirement_type": "type",
"groups": {
"['standard maximum resection', 'stereotactic biopsy']": {
"expected_value": [
"standard maximum resection",
"stereotactic biopsy"
],
"trial_ids": [
"NCT00002620"
],
"truth_value": "unknown"
}
}
},
"timing": {
"requirement_type": "timing",
"groups": {
"within 4 weeks prior to therapy": {
"expected_value": "within 4 weeks prior to therapy",
"trial_ids": [
"NCT00002620"
],
"truth_value": "unknown"
}
}
}
}
},
"white blood cell count": {
"criterion": "white blood cell count",
"requirements": {
"minimum count": {
"requirement_type": "minimum count",
"groups": {
"operator=<LLMOperator.GREATER_THAN: '>'> value=4000 unit='N/A'": {
"expected_value": {
"operator": ">",
"value": 4000,
"unit": "N/A"
},
"trial_ids": [
"NCT00002620"
],
"truth_value": "unknown"
}
}
}
}
},
"bilirubin level": {
"criterion": "bilirubin level",
"requirements": {
"maximum level": {
"requirement_type": "maximum level",
"groups": {
"operator=<LLMOperator.LESS_THAN: '<'> value=2 unit='mg/dl'": {
"expected_value": {
"operator": "<",
"value": 2,
"unit": "mg/dl"
},
"trial_ids": [
"NCT00002620"
],
"truth_value": "unknown"
}
}
}
}
},
"creatinine level": {
"criterion": "creatinine level",
"requirements": {
"maximum level": {
"requirement_type": "maximum level",
"groups": {
"operator=<LLMOperator.LESS_THAN: '<'> value=1.5 unit='mg/dl'": {
"expected_value": {
"operator": "<",
"value": 1.5,
"unit": "mg/dl"
},
"trial_ids": [
"NCT00002620"
],
"truth_value": "unknown"
}
}
}
}
},
"blood urea nitrogen level": {
"criterion": "blood urea nitrogen level",
"requirements": {
"maximum level": {
"requirement_type": "maximum level",
"groups": {
"operator=<LLMOperator.LESS_THAN: '<'> value=40 unit='mg/dl'": {
"expected_value": {
"operator": "<",
"value": 40,
"unit": "mg/dl"
},
"trial_ids": [
"NCT00002620"
],
"truth_value": "unknown"
}
}
}
}
},
"major medical illness": {
"criterion": "major medical illness",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002620"
],
"truth_value": "unknown"
}
}
}
}
},
"anticancer drugs": {
"criterion": "anticancer drugs",
"requirements": {
"usage": {
"requirement_type": "usage",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002620"
],
"truth_value": "unknown"
}
}
}
}
},
"steroids": {
"criterion": "steroids",
"requirements": {
"usage": {
"requirement_type": "usage",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002620"
],
"truth_value": "unknown"
}
}
}
}
},
"primary squamous cell or adenocarcinoma of the esophagus": {
"criterion": "primary squamous cell or adenocarcinoma of the esophagus",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"True": {
"expected_value": true,
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
}
}
},
"clinical stage": {
"criterion": "clinical stage",
"requirements": {
"stage": {
"requirement_type": "stage",
"groups": {
"['T1', 'T2', 'T3', 'T4']": {
"expected_value": [
"T1",
"T2",
"T3",
"T4"
],
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
},
"node involvement": {
"requirement_type": "node involvement",
"groups": {
"Nx": {
"expected_value": "Nx",
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
},
"metastasis": {
"requirement_type": "metastasis",
"groups": {
"M0": {
"expected_value": "M0",
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
}
}
},
"disease location": {
"criterion": "disease location",
"requirements": {
"location": {
"requirement_type": "location",
"groups": {
"esophagus and periesophageal soft tissue": {
"expected_value": "esophagus and periesophageal soft tissue",
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
}
}
},
"tumor extension": {
"criterion": "tumor extension",
"requirements": {
"distance from stomach": {
"requirement_type": "distance from stomach",
"groups": {
"operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=2 unit='cm'": {
"expected_value": {
"operator": ">=",
"value": 2,
"unit": "cm"
},
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
}
}
},
"invasion of the tracheal-bronchial tree": {
"criterion": "invasion of the tracheal-bronchial tree",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
}
}
},
"tracheal-esophageal (te) fistula": {
"criterion": "tracheal-esophageal (te) fistula",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
}
}
},
"bronchoscopy requirement": {
"criterion": "bronchoscopy requirement",
"requirements": {
"lesion distance from incisors": {
"requirement_type": "lesion distance from incisors",
"groups": {
"operator=<LLMOperator.LESS_THAN: '<'> value=30 unit='cm'": {
"expected_value": {
"operator": "<",
"value": 30,
"unit": "cm"
},
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
}
}
},
"liver biopsy": {
"criterion": "liver biopsy",
"requirements": {
"result": {
"requirement_type": "result",
"groups": {
"negative": {
"expected_value": "negative",
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
}
}
},
"retroperitoneal or celiac nodes biopsy": {
"criterion": "retroperitoneal or celiac nodes biopsy",
"requirements": {
"result": {
"requirement_type": "result",
"groups": {
"negative": {
"expected_value": "negative",
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
},
"node size": {
"requirement_type": "node size",
"groups": {
"operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=1.5 unit='cm'": {
"expected_value": {
"operator": ">=",
"value": 1.5,
"unit": "cm"
},
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
}
}
},
"supraclavicular nodes biopsy": {
"criterion": "supraclavicular nodes biopsy",
"requirements": {
"result": {
"requirement_type": "result",
"groups": {
"negative": {
"expected_value": "negative",
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
}
}
},
"recurrent disease": {
"criterion": "recurrent disease",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
}
}
},
"multiple carcinomas of the esophagus": {
"criterion": "multiple carcinomas of the esophagus",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
}
}
},
"growth factor administration": {
"criterion": "growth factor administration",
"requirements": {
"presence": {
"requirement_type": "presence",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
}
}
},
"chest irradiation": {
"criterion": "chest irradiation",
"requirements": {
"prior treatment": {
"requirement_type": "prior treatment",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
}
}
},
"resection": {
"criterion": "resection",
"requirements": {
"prior treatment": {
"requirement_type": "prior treatment",
"groups": {
"False": {
"expected_value": false,
"trial_ids": [
"NCT00002631"
],
"truth_value": "unknown"
}
}
}
}
}
}
}