{
    "info": {
        "nct_id": "NCT03034096",
        "official_title": "General Anesthetics in CAncer REsection Surgery (GA-CARES) Trial: Pragmatic Randomized Trial of Propofol vs Volatile Inhalational Anesthesia",
        "inclusion_criteria": "* Patients with known or suspected cancer and scheduled to undergo any of the following oncologic surgical procedures:\n\n  * Lobectomy or pneumonectomy\n  * Esophagectomy\n  * Radical (total) cystectomy\n  * Pancreatectomy\n  * Partial hepatectomy\n  * Hyperthermic intraperitoneal chemotherapy (HIPEC)\n  * Gastrectomy (subtotal or total)\n  * Cholecystectomy or bile duct resection\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* Age less than 18 years\n* American Society of Anesthesiologist Class 5\n* Projected life expectancy less than 30 days\n* Known or suspected hypersensitivity to either propofol, e.g. egg or soy allergy, or volatile general anesthetic agents\n* Known or suspected history of malignant hyperthermia",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Patients with known or suspected cancer and scheduled to undergo any of the following oncologic surgical procedures:",
            "criterions": [
                {
                    "exact_snippets": [
                        "known or suspected cancer"
                    ],
                    "criterion": "cancer",
                    "requirement_type": "presence",
                    "expected_value": true
                },
                {
                    "exact_snippets": [
                        "scheduled to undergo any of the following oncologic surgical procedures"
                    ],
                    "criterion": "oncologic surgical procedures",
                    "requirement_type": "scheduled",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "* Lobectomy or pneumonectomy",
            "criterions": [
                {
                    "exact_snippets": [
                        "Lobectomy"
                    ],
                    "criterion": "lobectomy",
                    "requirement_type": "history",
                    "expected_value": true
                },
                {
                    "exact_snippets": [
                        "pneumonectomy"
                    ],
                    "criterion": "pneumonectomy",
                    "requirement_type": "history",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "* Esophagectomy",
            "criterions": [
                {
                    "exact_snippets": [
                        "Esophagectomy"
                    ],
                    "criterion": "esophagectomy",
                    "requirement_type": "procedure",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "* Radical (total) cystectomy",
            "criterions": [
                {
                    "exact_snippets": [
                        "Radical (total) cystectomy"
                    ],
                    "criterion": "cystectomy",
                    "requirement_type": "type",
                    "expected_value": "radical (total)"
                }
            ]
        },
        {
            "line": "* Pancreatectomy",
            "criterions": [
                {
                    "exact_snippets": [
                        "Pancreatectomy"
                    ],
                    "criterion": "pancreatectomy",
                    "requirement_type": "history",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "* Partial hepatectomy",
            "criterions": [
                {
                    "exact_snippets": [
                        "Partial hepatectomy"
                    ],
                    "criterion": "hepatectomy",
                    "requirement_type": "type",
                    "expected_value": "partial"
                }
            ]
        },
        {
            "line": "* Hyperthermic intraperitoneal chemotherapy (HIPEC)",
            "criterions": [
                {
                    "exact_snippets": [
                        "Hyperthermic intraperitoneal chemotherapy (HIPEC)"
                    ],
                    "criterion": "Hyperthermic intraperitoneal chemotherapy",
                    "requirement_type": "N/A",
                    "expected_value": "HIPEC"
                }
            ]
        },
        {
            "line": "* Gastrectomy (subtotal or total)",
            "criterions": [
                {
                    "exact_snippets": [
                        "Gastrectomy (subtotal or total)"
                    ],
                    "criterion": "gastrectomy",
                    "requirement_type": "type",
                    "expected_value": [
                        "subtotal",
                        "total"
                    ]
                }
            ]
        },
        {
            "line": "* Cholecystectomy or bile duct resection",
            "criterions": [
                {
                    "exact_snippets": [
                        "Cholecystectomy"
                    ],
                    "criterion": "cholecystectomy",
                    "requirement_type": "history",
                    "expected_value": true
                },
                {
                    "exact_snippets": [
                        "bile duct resection"
                    ],
                    "criterion": "bile duct resection",
                    "requirement_type": "history",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": [
                        "Healthy volunteers allowed"
                    ],
                    "criterion": "healthy volunteers",
                    "requirement_type": "participation",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": [
                        "minimum age of 18 Years"
                    ],
                    "criterion": "age",
                    "requirement_type": "minimum",
                    "expected_value": {
                        "operator": ">=",
                        "value": 18
                    }
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Age less than 18 years",
            "criterions": [
                {
                    "exact_snippets": [
                        "Age less than 18 years"
                    ],
                    "criterion": "age",
                    "requirement_type": "range",
                    "expected_value": {
                        "comparisons": [
                            {
                                "operator": "<",
                                "value": 18
                            }
                        ]
                    }
                }
            ]
        },
        {
            "line": "* American Society of Anesthesiologist Class 5",
            "criterions": [
                {
                    "exact_snippets": [
                        "American Society of Anesthesiologist Class 5"
                    ],
                    "criterion": "American Society of Anesthesiologist Class",
                    "requirement_type": "classification",
                    "expected_value": "5"
                }
            ]
        },
        {
            "line": "* Projected life expectancy less than 30 days",
            "criterions": [
                {
                    "exact_snippets": [
                        "Projected life expectancy less than 30 days"
                    ],
                    "criterion": "life expectancy",
                    "requirement_type": "quantity",
                    "expected_value": {
                        "operator": "<",
                        "value": 30
                    }
                }
            ]
        },
        {
            "line": "* Known or suspected hypersensitivity to either propofol, e.g. egg or soy allergy, or volatile general anesthetic agents",
            "criterions": [
                {
                    "exact_snippets": [
                        "Known or suspected hypersensitivity to either propofol"
                    ],
                    "criterion": "hypersensitivity to propofol",
                    "requirement_type": "presence",
                    "expected_value": true
                },
                {
                    "exact_snippets": [
                        "egg or soy allergy"
                    ],
                    "criterion": "egg or soy allergy",
                    "requirement_type": "presence",
                    "expected_value": true
                },
                {
                    "exact_snippets": [
                        "hypersensitivity to",
                        "volatile general anesthetic agents"
                    ],
                    "criterion": "hypersensitivity to volatile general anesthetic agents",
                    "requirement_type": "presence",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "* Known or suspected history of malignant hyperthermia",
            "criterions": [
                {
                    "exact_snippets": [
                        "Known or suspected history of malignant hyperthermia"
                    ],
                    "criterion": "malignant hyperthermia",
                    "requirement_type": "history",
                    "expected_value": true
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}