{
    "info": {
        "nct_id": "NCT02334722",
        "official_title": "A Shortened Antiepileptic Drug (AED) Course in Surgical Brain Tumor Patients: A Randomized Trial",
        "inclusion_criteria": "* Adult (>18 years of age and older) patients who have or will have undergone surgical resection or biopsy of a supratentorial brain tumor and are able to consent for themselves.\n* Able to be randomized prior to or up to 48 hours after surgery.\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* No known history of seizure activity.\n* Pregnant or breastfeeding.\n* Renal dysfunction (CrCl < 30ml/min).\n* Beck's Depression Inventory (BDI) ≥14\n* Allergy to levetiracetam.",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Adult (>18 years of age and older) patients who have or will have undergone surgical resection or biopsy of a supratentorial brain tumor and are able to consent for themselves.",
            "criterions": [
                {
                    "exact_snippets": [
                        "Adult (>18 years of age and older)"
                    ],
                    "criterion": "age",
                    "requirement_type": "range",
                    "expected_value": {
                        "comparisons": [
                            {
                                "operator": ">",
                                "value": 18
                            }
                        ]
                    }
                },
                {
                    "exact_snippets": [
                        "undergone surgical resection or biopsy of a supratentorial brain tumor"
                    ],
                    "criterion": "surgical resection or biopsy",
                    "requirement_type": "procedure",
                    "expected_value": true
                },
                {
                    "exact_snippets": [
                        "supratentorial brain tumor"
                    ],
                    "criterion": "supratentorial brain tumor",
                    "requirement_type": "presence",
                    "expected_value": true
                },
                {
                    "exact_snippets": [
                        "able to consent for themselves"
                    ],
                    "criterion": "ability to consent",
                    "requirement_type": "capability",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "* Able to be randomized prior to or up to 48 hours after surgery.",
            "criterions": [
                {
                    "exact_snippets": [
                        "Able to be randomized prior to or up to 48 hours after surgery"
                    ],
                    "criterion": "randomization",
                    "requirement_type": "timing",
                    "expected_value": "prior to or up to 48 hours after surgery"
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": [
                        "Healthy volunteers allowed"
                    ],
                    "criterion": "healthy volunteers",
                    "requirement_type": "participation",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": [
                        "minimum age of 18 Years"
                    ],
                    "criterion": "age",
                    "requirement_type": "minimum",
                    "expected_value": {
                        "operator": ">=",
                        "value": 18
                    }
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* No known history of seizure activity.",
            "criterions": [
                {
                    "exact_snippets": [
                        "No known history of seizure activity"
                    ],
                    "criterion": "seizure activity",
                    "requirement_type": "history",
                    "expected_value": false
                }
            ]
        },
        {
            "line": "* Pregnant or breastfeeding.",
            "criterions": [
                {
                    "exact_snippets": [
                        "Pregnant"
                    ],
                    "criterion": "pregnancy",
                    "requirement_type": "status",
                    "expected_value": true
                },
                {
                    "exact_snippets": [
                        "breastfeeding"
                    ],
                    "criterion": "breastfeeding",
                    "requirement_type": "status",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "* Renal dysfunction (CrCl < 30ml/min).",
            "criterions": [
                {
                    "exact_snippets": [
                        "Renal dysfunction"
                    ],
                    "criterion": "renal function",
                    "requirement_type": "status",
                    "expected_value": "dysfunction"
                },
                {
                    "exact_snippets": [
                        "CrCl < 30ml/min"
                    ],
                    "criterion": "creatinine clearance",
                    "requirement_type": "quantity",
                    "expected_value": {
                        "operator": "<",
                        "value": 30
                    }
                }
            ]
        },
        {
            "line": "* Beck's Depression Inventory (BDI) ≥14",
            "criterions": [
                {
                    "exact_snippets": [
                        "Beck's Depression Inventory (BDI) ≥14"
                    ],
                    "criterion": "Beck's Depression Inventory (BDI)",
                    "requirement_type": "score",
                    "expected_value": {
                        "comparisons": [
                            {
                                "operator": ">=",
                                "value": 14
                            }
                        ]
                    }
                }
            ]
        },
        {
            "line": "* Allergy to levetiracetam.",
            "criterions": [
                {
                    "exact_snippets": [
                        "Allergy to levetiracetam"
                    ],
                    "criterion": "levetiracetam",
                    "requirement_type": "allergy",
                    "expected_value": true
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}