{
    "info": {
        "nct_id": "NCT01768195",
        "official_title": "Prophylactic Use of Entecavir for HBsAg Positive Lymphoma Patients Treated With Rituximab-based Immunochemotherapy",
        "inclusion_criteria": "* treatment-naive patients with B-cell lymphoma\n* HBsAg positive at baseline\n* treated with rituximab-based immunochemotherapy\n* life expectancy of more than 3 months\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* younger than 18 years old\n* HBsAg negative at baseline\n* pregnant or lactating women",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* treatment-naive patients with B-cell lymphoma",
            "criterions": [
                {
                    "exact_snippets": [
                        "treatment-naive"
                    ],
                    "criterion": "treatment status",
                    "requirement_type": "status",
                    "expected_value": "naive"
                },
                {
                    "exact_snippets": [
                        "B-cell lymphoma"
                    ],
                    "criterion": "B-cell lymphoma",
                    "requirement_type": "presence",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "* HBsAg positive at baseline",
            "criterions": [
                {
                    "exact_snippets": [
                        "HBsAg positive"
                    ],
                    "criterion": "HBsAg",
                    "requirement_type": "presence",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "* treated with rituximab-based immunochemotherapy",
            "criterions": [
                {
                    "exact_snippets": [
                        "treated with rituximab-based immunochemotherapy"
                    ],
                    "criterion": "rituximab-based immunochemotherapy",
                    "requirement_type": "treatment",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "* life expectancy of more than 3 months",
            "criterions": [
                {
                    "exact_snippets": [
                        "life expectancy",
                        "more than 3 months"
                    ],
                    "criterion": "life expectancy",
                    "requirement_type": "duration",
                    "expected_value": {
                        "operator": ">",
                        "value": 3
                    }
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": [
                        "Healthy volunteers allowed"
                    ],
                    "criterion": "healthy volunteers",
                    "requirement_type": "participation",
                    "expected_value": true
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": [
                        "minimum age of 18 Years"
                    ],
                    "criterion": "age",
                    "requirement_type": "minimum",
                    "expected_value": {
                        "operator": ">=",
                        "value": 18
                    }
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* younger than 18 years old",
            "criterions": [
                {
                    "exact_snippets": [
                        "younger than 18 years old"
                    ],
                    "criterion": "age",
                    "requirement_type": "range",
                    "expected_value": {
                        "comparisons": [
                            {
                                "operator": "<",
                                "value": 18
                            }
                        ]
                    }
                }
            ]
        },
        {
            "line": "* HBsAg negative at baseline",
            "criterions": [
                {
                    "exact_snippets": [
                        "HBsAg negative"
                    ],
                    "criterion": "HBsAg",
                    "requirement_type": "presence",
                    "expected_value": false
                }
            ]
        },
        {
            "line": "* pregnant or lactating women",
            "criterions": [
                {
                    "exact_snippets": [
                        "pregnant"
                    ],
                    "criterion": "pregnancy",
                    "requirement_type": "status",
                    "expected_value": true
                },
                {
                    "exact_snippets": [
                        "lactating"
                    ],
                    "criterion": "lactation",
                    "requirement_type": "status",
                    "expected_value": true
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}