{
    "info": {
        "nct_id": "NCT06332976",
        "official_title": "Patients' Preferences for Adjuvant or Neoadjuvant Chemotherapy in Breast Cancer",
        "inclusion_criteria": "* Patients with early or locally advanced breast cancer\n* Patients candidate to adjuvant/neoadjuvant chemotherapy or patients who are receiving adjuvant/neoadjuvant chemotherapy or patients who received adjuvant/neoadjuvant chemotherapy\n* Sufficient literacy in Italian to complete the questionnaires\n* Patients must provide signed, written or advanced electronic signature (AES or AdES), informed consent\nHealthy volunteers allowed\nMust be FEMALE\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* None",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* Patients candidate to adjuvant/neoadjuvant chemotherapy or patients who are receiving adjuvant/neoadjuvant chemotherapy or patients who received adjuvant/neoadjuvant chemotherapy",
                "criterions": [
                    {
                        "exact_snippets": "Patients candidate to adjuvant/neoadjuvant chemotherapy",
                        "criterion": "adjuvant/neoadjuvant chemotherapy candidacy",
                        "requirement": {
                            "requirement_type": "candidacy",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "patients who are receiving adjuvant/neoadjuvant chemotherapy",
                        "criterion": "adjuvant/neoadjuvant chemotherapy",
                        "requirement": {
                            "requirement_type": "current treatment",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "patients who received adjuvant/neoadjuvant chemotherapy",
                        "criterion": "adjuvant/neoadjuvant chemotherapy",
                        "requirement": {
                            "requirement_type": "past treatment",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": "Patients candidate to adjuvant/neoadjuvant chemotherapy",
                        "criterion": "adjuvant/neoadjuvant chemotherapy candidacy",
                        "requirement": {
                            "requirement_type": "candidacy",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "patients who are receiving adjuvant/neoadjuvant chemotherapy",
                        "criterion": "adjuvant/neoadjuvant chemotherapy",
                        "requirement": {
                            "requirement_type": "current treatment",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "patients who received adjuvant/neoadjuvant chemotherapy",
                        "criterion": "adjuvant/neoadjuvant chemotherapy",
                        "requirement": {
                            "requirement_type": "past treatment",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Sufficient literacy in Italian to complete the questionnaires",
                "criterions": [
                    {
                        "exact_snippets": "Sufficient literacy in Italian",
                        "criterion": "literacy in Italian",
                        "requirement": {
                            "requirement_type": "sufficiency",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Sufficient literacy in Italian",
                        "criterion": "literacy in Italian",
                        "requirement": {
                            "requirement_type": "sufficiency",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Patients must provide signed, written or advanced electronic signature (AES or AdES), informed consent",
                "criterions": [
                    {
                        "exact_snippets": "Patients must provide signed, written or advanced electronic signature (AES or AdES), informed consent",
                        "criterion": "informed consent",
                        "requirement": {
                            "requirement_type": "provision",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "or_criteria": [
                            {
                                "and_criteria": [
                                    {
                                        "exact_snippets": "Patients must provide signed, written or advanced electronic signature (AES or AdES), informed consent",
                                        "criterion": "informed consent",
                                        "requirement": {
                                            "requirement_type": "provision",
                                            "expected_value": true
                                        }
                                    },
                                    {
                                        "exact_snippets": "Patients must provide signed, written or advanced electronic signature (AES or AdES), informed consent",
                                        "criterion": "signature type",
                                        "requirement": {
                                            "requirement_type": "type",
                                            "expected_value": "signed"
                                        }
                                    }
                                ]
                            },
                            {
                                "and_criteria": [
                                    {
                                        "exact_snippets": "Patients must provide signed, written or advanced electronic signature (AES or AdES), informed consent",
                                        "criterion": "informed consent",
                                        "requirement": {
                                            "requirement_type": "provision",
                                            "expected_value": true
                                        }
                                    },
                                    {
                                        "exact_snippets": "Patients must provide signed, written or advanced electronic signature (AES or AdES), informed consent",
                                        "criterion": "signature type",
                                        "requirement": {
                                            "requirement_type": "type",
                                            "expected_value": "written"
                                        }
                                    }
                                ]
                            },
                            {
                                "and_criteria": [
                                    {
                                        "exact_snippets": "Patients must provide signed, written or advanced electronic signature (AES or AdES), informed consent",
                                        "criterion": "informed consent",
                                        "requirement": {
                                            "requirement_type": "provision",
                                            "expected_value": true
                                        }
                                    },
                                    {
                                        "or_criteria": [
                                            {
                                                "exact_snippets": "Patients must provide signed, written or advanced electronic signature (AES or AdES), informed consent",
                                                "criterion": "signature type",
                                                "requirement": {
                                                    "requirement_type": "type",
                                                    "expected_value": "AES"
                                                }
                                            },
                                            {
                                                "exact_snippets": "Patients must provide signed, written or advanced electronic signature (AES or AdES), informed consent",
                                                "criterion": "signature type",
                                                "requirement": {
                                                    "requirement_type": "type",
                                                    "expected_value": "AdES"
                                                }
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must be FEMALE",
                "criterions": [
                    {
                        "exact_snippets": "Must be FEMALE",
                        "criterion": "gender",
                        "requirement": {
                            "requirement_type": "N/A",
                            "expected_value": "female"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Must be FEMALE",
                        "criterion": "gender",
                        "requirement": {
                            "requirement_type": "N/A",
                            "expected_value": "female"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 18 Years",
                "criterions": [
                    {
                        "exact_snippets": "minimum age of 18 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "minimum age of 18 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "* None",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [
        {
            "identified_line": {
                "line": "* Patients with early or locally advanced breast cancer",
                "criterions": [
                    {
                        "exact_snippets": "early or locally advanced breast cancer",
                        "criterion": "breast cancer",
                        "requirement": {
                            "requirement_type": "stage",
                            "expected_value": [
                                "early",
                                "locally advanced"
                            ]
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": "early or locally advanced breast cancer",
                        "criterion": "breast cancer",
                        "requirement": {
                            "requirement_type": "stage",
                            "expected_value": "early"
                        }
                    },
                    {
                        "exact_snippets": "early or locally advanced breast cancer",
                        "criterion": "breast cancer",
                        "requirement": {
                            "requirement_type": "stage",
                            "expected_value": "locally advanced"
                        }
                    }
                ]
            }
        }
    ],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}