{
    "info": {
        "nct_id": "NCT05633680",
        "official_title": "Detection of Folate Receptor-positive Circulating Tumor Cells as a Biomarker for Diagnosis",
        "inclusion_criteria": "Clinical diagnosis of breast cancer Must be able to cooperate with the examination\nHealthy volunteers allowed\nMust be FEMALE\nMust have minimum age of 18 Years\nMust have maximum age of 85 Years",
        "exclusion_criteria": "patients were currently undergoing or had prior cancer treatment; patients had other conditions which investigators thought not suitable for the study.",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "Clinical diagnosis of breast cancer Must be able to cooperate with the examination",
                "criterions": [
                    {
                        "exact_snippets": "Clinical diagnosis of breast cancer",
                        "criterion": "breast cancer",
                        "requirement": {
                            "requirement_type": "diagnosis",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "Must be able to cooperate with the examination",
                        "criterion": "ability to cooperate with examination",
                        "requirement": {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Clinical diagnosis of breast cancer",
                        "criterion": "breast cancer",
                        "requirement": {
                            "requirement_type": "diagnosis",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "Must be able to cooperate with the examination",
                        "criterion": "ability to cooperate with examination",
                        "requirement": {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must be FEMALE",
                "criterions": [
                    {
                        "exact_snippets": "Must be FEMALE",
                        "criterion": "gender",
                        "requirement": {
                            "requirement_type": "expected_value",
                            "expected_value": "female"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Must be FEMALE",
                        "criterion": "gender",
                        "requirement": {
                            "requirement_type": "expected_value",
                            "expected_value": "female"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 18 Years",
                "criterions": [
                    {
                        "exact_snippets": "minimum age of 18 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "minimum age of 18 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have maximum age of 85 Years",
                "criterions": [
                    {
                        "exact_snippets": "maximum age of 85 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 85,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "maximum age of 85 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 85,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "patients were currently undergoing or had prior cancer treatment; patients had other conditions which investigators thought not suitable for the study.",
                "criterions": [
                    {
                        "exact_snippets": "currently undergoing or had prior cancer treatment",
                        "criterion": "cancer treatment history",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": [
                                "currently undergoing",
                                "had prior"
                            ]
                        }
                    },
                    {
                        "exact_snippets": "other conditions which investigators thought not suitable for the study",
                        "criterion": "other medical conditions",
                        "requirement": {
                            "requirement_type": "suitability",
                            "expected_value": "not suitable for the study"
                        }
                    }
                ]
            },
            "logical_structure": {
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                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "currently undergoing or had prior cancer treatment",
                                "criterion": "cancer treatment history",
                                "requirement": {
                                    "requirement_type": "status",
                                    "expected_value": [
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                                        "had prior"
                                    ]
                                }
                            }
                        ]
                    },
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "other conditions which investigators thought not suitable for the study",
                                "criterion": "other medical conditions",
                                "requirement": {
                                    "requirement_type": "suitability",
                                    "expected_value": "not suitable for the study"
                                }
                            }
                        ]
                    }
                ]
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}