{
    "info": {
        "nct_id": "NCT05170360",
        "official_title": "Evaluation of Some Risk Factors Associated With Colorectal Cancer and Their Correlation With KRAS and BRAF Genes Mutations",
        "inclusion_criteria": "- 1. Patients who are recently diagnosed with CRC based on clinical and pathological examinations.\n\n2. Control subjects will be CRC-free, based on the clinical history and physical examination.",
        "exclusion_criteria": "1 - Patient refuses to be enrolled in the study. 2. Subjects with cancer metastasized from other tissues to the colon. (colon is the site of metastasis)",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "- 1. Patients who are recently diagnosed with CRC based on clinical and pathological examinations.",
                "criterions": [
                    {
                        "exact_snippets": "recently diagnosed with CRC",
                        "criterion": "CRC diagnosis",
                        "requirement": {
                            "requirement_type": "recency",
                            "expected_value": "recently"
                        }
                    },
                    {
                        "exact_snippets": "based on clinical and pathological examinations",
                        "criterion": "diagnosis method",
                        "requirement": {
                            "requirement_type": "methods",
                            "expected_value": [
                                "clinical examinations",
                                "pathological examinations"
                            ]
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "recently diagnosed with CRC",
                        "criterion": "CRC diagnosis",
                        "requirement": {
                            "requirement_type": "recency",
                            "expected_value": "recently"
                        }
                    },
                    {
                        "exact_snippets": "based on clinical and pathological examinations",
                        "criterion": "diagnosis method",
                        "requirement": {
                            "requirement_type": "methods",
                            "expected_value": [
                                "clinical examinations",
                                "pathological examinations"
                            ]
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "2. Control subjects will be CRC-free, based on the clinical history and physical examination.",
                "criterions": [
                    {
                        "exact_snippets": "CRC-free",
                        "criterion": "CRC (Colorectal Cancer)",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "clinical history",
                        "criterion": "clinical history",
                        "requirement": {
                            "requirement_type": "CRC status",
                            "expected_value": "free"
                        }
                    },
                    {
                        "exact_snippets": "physical examination",
                        "criterion": "physical examination",
                        "requirement": {
                            "requirement_type": "CRC status",
                            "expected_value": "free"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "clinical history",
                                "criterion": "clinical history",
                                "requirement": {
                                    "requirement_type": "CRC status",
                                    "expected_value": "free"
                                }
                            },
                            {
                                "exact_snippets": "physical examination",
                                "criterion": "physical examination",
                                "requirement": {
                                    "requirement_type": "CRC status",
                                    "expected_value": "free"
                                }
                            }
                        ]
                    },
                    {
                        "exact_snippets": "CRC-free",
                        "criterion": "CRC (Colorectal Cancer)",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "1 - Patient refuses to be enrolled in the study. 2. Subjects with cancer metastasized from other tissues to the colon. (colon is the site of metastasis)",
                "criterions": [
                    {
                        "exact_snippets": "Patient refuses to be enrolled in the study",
                        "criterion": "patient consent",
                        "requirement": {
                            "requirement_type": "consent",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "Subjects with cancer metastasized from other tissues to the colon",
                        "criterion": "cancer metastasis to colon",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": "Patient refuses to be enrolled in the study",
                        "criterion": "patient consent",
                        "requirement": {
                            "requirement_type": "consent",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "Subjects with cancer metastasized from other tissues to the colon",
                        "criterion": "cancer metastasis to colon",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}