{
    "info": {
        "nct_id": "NCT04666220",
        "official_title": "Vessels Encapsulating Tumor Clusters (VETC), Prognostic and Predictive Value in Renal Cell Carcinoma and Adrenal Gland Carcinoma",
        "inclusion_criteria": "1. Histological diagnosis of Renal Cell Carcinoma;\n2. Histological diagnosis of Carcinoma of the adrenal gland;\n3. Availability of histological material;\n4. For the evaluation of the prognostic role: no systemic treatment with TKI administered before surgery.\nHealthy volunteers allowed",
        "exclusion_criteria": "1. Unavailable histological material;\n2. For RCC: histological diagnosis different from Clear Cell histotype.",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "1. Histological diagnosis of Renal Cell Carcinoma;",
                "criterions": [
                    {
                        "exact_snippets": "Histological diagnosis of Renal Cell Carcinoma",
                        "criterion": "Renal Cell Carcinoma",
                        "requirement": {
                            "requirement_type": "diagnosis",
                            "expected_value": "histological"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Histological diagnosis of Renal Cell Carcinoma",
                        "criterion": "Renal Cell Carcinoma",
                        "requirement": {
                            "requirement_type": "diagnosis",
                            "expected_value": "histological"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "2. Histological diagnosis of Carcinoma of the adrenal gland;",
                "criterions": [
                    {
                        "exact_snippets": "Histological diagnosis of Carcinoma of the adrenal gland",
                        "criterion": "Carcinoma of the adrenal gland",
                        "requirement": {
                            "requirement_type": "diagnosis",
                            "expected_value": "histological"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Histological diagnosis of Carcinoma of the adrenal gland",
                        "criterion": "Carcinoma of the adrenal gland",
                        "requirement": {
                            "requirement_type": "diagnosis",
                            "expected_value": "histological"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "3. Availability of histological material;",
                "criterions": [
                    {
                        "exact_snippets": "Availability of histological material",
                        "criterion": "histological material",
                        "requirement": {
                            "requirement_type": "availability",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Availability of histological material",
                        "criterion": "histological material",
                        "requirement": {
                            "requirement_type": "availability",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "4. For the evaluation of the prognostic role: no systemic treatment with TKI administered before surgery.",
                "criterions": [
                    {
                        "exact_snippets": "no systemic treatment with TKI administered before surgery",
                        "criterion": "systemic treatment with TKI",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "no systemic treatment with TKI administered before surgery",
                        "criterion": "systemic treatment with TKI",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "1. Unavailable histological material;",
                "criterions": [
                    {
                        "exact_snippets": "Unavailable histological material",
                        "criterion": "histological material",
                        "requirement": {
                            "requirement_type": "availability",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Unavailable histological material",
                        "criterion": "histological material",
                        "requirement": {
                            "requirement_type": "availability",
                            "expected_value": false
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "2. For RCC: histological diagnosis different from Clear Cell histotype.",
                "criterions": [
                    {
                        "exact_snippets": "RCC: histological diagnosis different from Clear Cell histotype",
                        "criterion": "RCC histological diagnosis",
                        "requirement": {
                            "requirement_type": "histotype",
                            "expected_value": "different from Clear Cell"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "RCC: histological diagnosis different from Clear Cell histotype",
                        "criterion": "RCC histological diagnosis",
                        "requirement": {
                            "requirement_type": "histotype",
                            "expected_value": "different from Clear Cell"
                        }
                    }
                ]
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}