{
    "info": {
        "nct_id": "NCT03982082",
        "official_title": "Feasibility Study of Ultrasound to Evaluate Muscle-Glycogen Content in Patients With Cancer",
        "inclusion_criteria": "* Participants are willing and able to give written informed consent and to comply with study procedures.\n* Patients with a biopsy-confirmed solid malignant neoplasm with at least one neurologically-intact lower extremity, who fit into one of the following groups:\n\n  * Group 1: Patients with cachexia, defined by loss of > 5% of body weight over the preceding 6-months (in absence of simple starvation defined as intentional weight loss) or weight loss > 2% with BMI < 20.\n  * Group 2: Patients without cachexia, as defined above.\n* Patients who have a record of weight or BMI over preceding 6-months.\n* Patients must be receiving rehabilitation that includes exercise under the direction of a physical therapist.\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* Non-English speaking patients.\n* Patient with neurological compromise of both lower extremities causing muscle atrophy.\n* Underlying unstable medical condition (i.e: cardiac, pulmonary, or hematological) or musculoskeletal injury, which in the opinion of the investigator, limits participation in exercise of the measured lower extremity.\n* Patients who are unable to understand or follow through with study instructions.",
        "miscellaneous_criteria": ""
    },
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                    },
                    {
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                "line": "* Patients with a biopsy-confirmed solid malignant neoplasm with at least one neurologically-intact lower extremity, who fit into one of the following groups:",
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                            "requirement_type": "confirmation",
                            "expected_value": "biopsy-confirmed"
                        }
                    },
                    {
                        "exact_snippets": "at least one neurologically-intact lower extremity",
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                        "requirement": {
                            "requirement_type": "quantity",
                            "expected_value": {
                                "operator": ">=",
                                "value": 1,
                                "unit": "extremity"
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                "line": "* Group 1: Patients with cachexia, defined by loss of > 5% of body weight over the preceding 6-months (in absence of simple starvation defined as intentional weight loss) or weight loss > 2% with BMI < 20.",
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                                        "unit": "%"
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                                        "unit": "%"
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                                        "unit": ""
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                                        "criterion": "cachexia",
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                                            "requirement_type": "weight loss",
                                            "expected_value": {
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                                                    {
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                                            "expected_value": "preceding 6-months"
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                            {
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                                "criterion": "simple starvation",
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                                "exact_snippets": "weight loss > 2% with BMI < 20",
                                "criterion": "weight loss",
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                                    "expected_value": {
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                                                "value": 2,
                                                "unit": "%"
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                            {
                                "exact_snippets": "weight loss > 2% with BMI < 20",
                                "criterion": "weight loss",
                                "requirement": {
                                    "requirement_type": "BMI",
                                    "expected_value": {
                                        "comparisons": [
                                            {
                                                "operator": "<",
                                                "value": 20,
                                                "unit": ""
                                            }
                                        ]
                                    }
                                }
                            }
                        ]
                    }
                ]
            }
        },
        {
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                "line": "* Group 2: Patients without cachexia, as defined above.",
                "criterions": [
                    {
                        "exact_snippets": "Patients without cachexia",
                        "criterion": "cachexia",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
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                        "exact_snippets": "Patients without cachexia",
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                            "expected_value": false
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Patients who have a record of weight or BMI over preceding 6-months.",
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                        }
                    },
                    {
                        "exact_snippets": "record of ... BMI",
                        "criterion": "BMI record",
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                        }
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        {
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                                "value": 18,
                                "unit": "Years"
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        {
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                "line": "* Non-English speaking patients.",
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                        "exact_snippets": "Non-English speaking patients",
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        {
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                "criterions": [
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    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [
        {
            "identified_line": {
                "line": "* Patients who are unable to understand or follow through with study instructions.",
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                    {
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    "failed_miscellaneous": []
}