{
    "info": {
        "nct_id": "NCT03613194",
        "official_title": "Mechanistic and Molecular Study of the Process of Metastatic Dissemination in Colorectal Cancer",
        "inclusion_criteria": "* Age > 18 years\n* Histological Diagnosis of stage IV colorectal cancer\n* Hepatic metastasis and/or peritoneal potentially resecable\n* Patient affiliated with a mode of the social security or recipient of such a mode\n* Information of the patient or his legal representative and collection of his assent\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* None metastatic colorectal cancer\n* Cancer of appendicular origin\n* Patients deprived of liberty or unable to give his assent",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* Age > 18 years",
                "criterions": [
                    {
                        "exact_snippets": "Age > 18 years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
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                    {
                        "exact_snippets": "Age > 18 years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    }
                ]
            }
        },
        {
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                "line": "* Histological Diagnosis of stage IV colorectal cancer",
                "criterions": [
                    {
                        "exact_snippets": "Histological Diagnosis",
                        "criterion": "histological diagnosis",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "stage IV colorectal cancer",
                        "criterion": "colorectal cancer stage",
                        "requirement": {
                            "requirement_type": "stage",
                            "expected_value": "IV"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Histological Diagnosis",
                        "criterion": "histological diagnosis",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "stage IV colorectal cancer",
                        "criterion": "colorectal cancer stage",
                        "requirement": {
                            "requirement_type": "stage",
                            "expected_value": "IV"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
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                "criterions": [
                    {
                        "exact_snippets": "Hepatic metastasis",
                        "criterion": "hepatic metastasis",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "peritoneal potentially resecable",
                        "criterion": "peritoneal metastasis",
                        "requirement": {
                            "requirement_type": "resectability",
                            "expected_value": true
                        }
                    }
                ]
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            "logical_structure": {
                "or_criteria": [
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "Hepatic metastasis",
                                "criterion": "hepatic metastasis",
                                "requirement": {
                                    "requirement_type": "presence",
                                    "expected_value": true
                                }
                            },
                            {
                                "exact_snippets": "peritoneal potentially resecable",
                                "criterion": "peritoneal metastasis",
                                "requirement": {
                                    "requirement_type": "resectability",
                                    "expected_value": true
                                }
                            }
                        ]
                    },
                    {
                        "exact_snippets": "peritoneal potentially resecable",
                        "criterion": "peritoneal metastasis",
                        "requirement": {
                            "requirement_type": "resectability",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Patient affiliated with a mode of the social security or recipient of such a mode",
                "criterions": [
                    {
                        "exact_snippets": "Patient affiliated with a mode of the social security",
                        "criterion": "social security affiliation",
                        "requirement": {
                            "requirement_type": "affiliation",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "recipient of such a mode",
                        "criterion": "social security recipient",
                        "requirement": {
                            "requirement_type": "recipient status",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
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                    {
                        "exact_snippets": "Patient affiliated with a mode of the social security",
                        "criterion": "social security affiliation",
                        "requirement": {
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                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "recipient of such a mode",
                        "criterion": "social security recipient",
                        "requirement": {
                            "requirement_type": "recipient status",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Information of the patient or his legal representative and collection of his assent",
                "criterions": [
                    {
                        "exact_snippets": "Information of the patient or his legal representative",
                        "criterion": "information consent",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "collection of his assent",
                        "criterion": "assent",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
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                        "and_criteria": [
                            {
                                "exact_snippets": "Information of the patient or his legal representative",
                                "criterion": "information consent",
                                "requirement": {
                                    "requirement_type": "presence",
                                    "expected_value": true
                                }
                            },
                            {
                                "exact_snippets": "collection of his assent",
                                "criterion": "assent",
                                "requirement": {
                                    "requirement_type": "presence",
                                    "expected_value": true
                                }
                            }
                        ]
                    },
                    {
                        "exact_snippets": "collection of his assent",
                        "criterion": "assent",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 18 Years",
                "criterions": [
                    {
                        "exact_snippets": "minimum age of 18 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "minimum age of 18 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "* None metastatic colorectal cancer",
                "criterions": [
                    {
                        "exact_snippets": "None metastatic colorectal cancer",
                        "criterion": "metastatic colorectal cancer",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "None metastatic colorectal cancer",
                    "criterion": "metastatic colorectal cancer",
                    "requirement": {
                        "requirement_type": "presence",
                        "expected_value": false
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Cancer of appendicular origin",
                "criterions": [
                    {
                        "exact_snippets": "Cancer of appendicular origin",
                        "criterion": "cancer origin",
                        "requirement": {
                            "requirement_type": "location",
                            "expected_value": "appendicular"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Cancer of appendicular origin",
                        "criterion": "cancer origin",
                        "requirement": {
                            "requirement_type": "location",
                            "expected_value": "appendicular"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Patients deprived of liberty or unable to give his assent",
                "criterions": [
                    {
                        "exact_snippets": "Patients deprived of liberty",
                        "criterion": "liberty status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "deprived"
                        }
                    },
                    {
                        "exact_snippets": "unable to give his assent",
                        "criterion": "ability to give assent",
                        "requirement": {
                            "requirement_type": "ability",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
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                        "exact_snippets": "Patients deprived of liberty",
                        "criterion": "liberty status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "deprived"
                        }
                    },
                    {
                        "exact_snippets": "unable to give his assent",
                        "criterion": "ability to give assent",
                        "requirement": {
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                            "expected_value": false
                        }
                    }
                ]
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}