{
    "info": {
        "nct_id": "NCT02662166",
        "official_title": "Magnetic Resonance Imaging of Bladder Cancer",
        "inclusion_criteria": "* Age: 18 to 85 years old\n* Suspected BC based on cystoscopical evaluation.\n* Mental status: Patients must be able to understand the meaning of the study\n* Informed consent: The patient must sign the appropriate Ethical Committee (EC) approved informed consent documents in the presence of the designated staff\nHealthy volunteers allowed\nMust have minimum age of 18 Years\nMust have maximum age of 85 Years",
        "exclusion_criteria": "* History of serious cardiovascular, liver or kidney disease\n* Uncontrolled serious infection\n* Contraindications for MRI (cardiac pacemaker, intracranial clips etc)\n* Patient refusing radical cystectomy or chemotherapy or BCG\n* Intravesical Bacillus Calmette-Guerin instillations within 6 months before the first MRI examination",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* Age: 18 to 85 years old",
                "criterions": [
                    {
                        "exact_snippets": "Age: 18 to 85 years old",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 18,
                                        "unit": "years"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 85,
                                        "unit": "years"
                                    }
                                ]
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Age: 18 to 85 years old",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 18,
                                        "unit": "years"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 85,
                                        "unit": "years"
                                    }
                                ]
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Suspected BC based on cystoscopical evaluation.",
                "criterions": [
                    {
                        "exact_snippets": "Suspected BC based on cystoscopical evaluation",
                        "criterion": "BC (Bladder Cancer)",
                        "requirement": {
                            "requirement_type": "diagnosis",
                            "expected_value": "suspected"
                        }
                    },
                    {
                        "exact_snippets": "Suspected BC based on cystoscopical evaluation",
                        "criterion": "BC (Bladder Cancer)",
                        "requirement": {
                            "requirement_type": "method",
                            "expected_value": "cystoscopical evaluation"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Suspected BC based on cystoscopical evaluation",
                        "criterion": "BC (Bladder Cancer)",
                        "requirement": {
                            "requirement_type": "diagnosis",
                            "expected_value": "suspected"
                        }
                    },
                    {
                        "exact_snippets": "Suspected BC based on cystoscopical evaluation",
                        "criterion": "BC (Bladder Cancer)",
                        "requirement": {
                            "requirement_type": "method",
                            "expected_value": "cystoscopical evaluation"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Mental status: Patients must be able to understand the meaning of the study",
                "criterions": [
                    {
                        "exact_snippets": "Mental status: Patients must be able to understand the meaning of the study",
                        "criterion": "mental status",
                        "requirement": {
                            "requirement_type": "understanding",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Mental status: Patients must be able to understand the meaning of the study",
                        "criterion": "mental status",
                        "requirement": {
                            "requirement_type": "understanding",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Informed consent: The patient must sign the appropriate Ethical Committee (EC) approved informed consent documents in the presence of the designated staff",
                "criterions": [
                    {
                        "exact_snippets": "The patient must sign the appropriate Ethical Committee (EC) approved informed consent documents",
                        "criterion": "informed consent",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "The patient must sign the appropriate Ethical Committee (EC) approved informed consent documents",
                        "criterion": "informed consent",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 18 Years",
                "criterions": [
                    {
                        "exact_snippets": "minimum age of 18 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "minimum age of 18 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have maximum age of 85 Years",
                "criterions": [
                    {
                        "exact_snippets": "maximum age of 85 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 85,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "maximum age of 85 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 85,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "* History of serious cardiovascular, liver or kidney disease",
                "criterions": [
                    {
                        "exact_snippets": "History of serious cardiovascular ... disease",
                        "criterion": "cardiovascular disease",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "History of serious cardiovascular ... disease",
                        "criterion": "cardiovascular disease",
                        "requirement": {
                            "requirement_type": "severity",
                            "expected_value": "serious"
                        }
                    },
                    {
                        "exact_snippets": "History of serious ... liver ... disease",
                        "criterion": "liver disease",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "History of serious ... liver ... disease",
                        "criterion": "liver disease",
                        "requirement": {
                            "requirement_type": "severity",
                            "expected_value": "serious"
                        }
                    },
                    {
                        "exact_snippets": "History of serious ... kidney disease",
                        "criterion": "kidney disease",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "History of serious ... kidney disease",
                        "criterion": "kidney disease",
                        "requirement": {
                            "requirement_type": "severity",
                            "expected_value": "serious"
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "History of serious cardiovascular ... disease",
                                "criterion": "cardiovascular disease",
                                "requirement": {
                                    "requirement_type": "history",
                                    "expected_value": true
                                }
                            },
                            {
                                "exact_snippets": "History of serious cardiovascular ... disease",
                                "criterion": "cardiovascular disease",
                                "requirement": {
                                    "requirement_type": "severity",
                                    "expected_value": "serious"
                                }
                            }
                        ]
                    },
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "History of serious ... liver ... disease",
                                "criterion": "liver disease",
                                "requirement": {
                                    "requirement_type": "history",
                                    "expected_value": true
                                }
                            },
                            {
                                "exact_snippets": "History of serious ... liver ... disease",
                                "criterion": "liver disease",
                                "requirement": {
                                    "requirement_type": "severity",
                                    "expected_value": "serious"
                                }
                            }
                        ]
                    },
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "History of serious ... kidney disease",
                                "criterion": "kidney disease",
                                "requirement": {
                                    "requirement_type": "history",
                                    "expected_value": true
                                }
                            },
                            {
                                "exact_snippets": "History of serious ... kidney disease",
                                "criterion": "kidney disease",
                                "requirement": {
                                    "requirement_type": "severity",
                                    "expected_value": "serious"
                                }
                            }
                        ]
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Uncontrolled serious infection",
                "criterions": [
                    {
                        "exact_snippets": "Uncontrolled serious infection",
                        "criterion": "serious infection",
                        "requirement": {
                            "requirement_type": "control status",
                            "expected_value": "uncontrolled"
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "Uncontrolled serious infection",
                    "criterion": "serious infection",
                    "requirement": {
                        "requirement_type": "control status",
                        "expected_value": "uncontrolled"
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Contraindications for MRI (cardiac pacemaker, intracranial clips etc)",
                "criterions": [
                    {
                        "exact_snippets": "Contraindications for MRI (cardiac pacemaker, intracranial clips etc)",
                        "criterion": "MRI contraindications",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": [
                                "cardiac pacemaker",
                                "intracranial clips"
                            ]
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Contraindications for MRI (cardiac pacemaker, intracranial clips etc)",
                        "criterion": "MRI contraindications",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": [
                                "cardiac pacemaker",
                                "intracranial clips"
                            ]
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Patient refusing radical cystectomy or chemotherapy or BCG",
                "criterions": [
                    {
                        "exact_snippets": "Patient refusing radical cystectomy",
                        "criterion": "radical cystectomy",
                        "requirement": {
                            "requirement_type": "refusal",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "Patient refusing ... chemotherapy",
                        "criterion": "chemotherapy",
                        "requirement": {
                            "requirement_type": "refusal",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "Patient refusing ... BCG",
                        "criterion": "BCG",
                        "requirement": {
                            "requirement_type": "refusal",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
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                        "exact_snippets": "Patient refusing radical cystectomy",
                        "criterion": "radical cystectomy",
                        "requirement": {
                            "requirement_type": "refusal",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "Patient refusing ... chemotherapy",
                        "criterion": "chemotherapy",
                        "requirement": {
                            "requirement_type": "refusal",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "Patient refusing ... BCG",
                        "criterion": "BCG",
                        "requirement": {
                            "requirement_type": "refusal",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Intravesical Bacillus Calmette-Guerin instillations within 6 months before the first MRI examination",
                "criterions": [
                    {
                        "exact_snippets": "Intravesical Bacillus Calmette-Guerin instillations within 6 months before the first MRI examination",
                        "criterion": "Intravesical Bacillus Calmette-Guerin instillations",
                        "requirement": {
                            "requirement_type": "time frame",
                            "expected_value": {
                                "operator": "<=",
                                "value": 6,
                                "unit": "months"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Intravesical Bacillus Calmette-Guerin instillations within 6 months before the first MRI examination",
                        "criterion": "Intravesical Bacillus Calmette-Guerin instillations",
                        "requirement": {
                            "requirement_type": "time frame",
                            "expected_value": {
                                "operator": "<=",
                                "value": 6,
                                "unit": "months"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}