{
    "info": {
        "nct_id": "NCT02519972",
        "official_title": "Low-dose Computed Tomography Screening for Lung Cancer in Relatives With Family History of Lung Cancer",
        "inclusion_criteria": "1. relatives of the lung cancer patients;\n2. age older than 55 years old or age older than the age of onset of lung cancer proband if the family members were less than 55 years old;\n3. compulsory signing the consent agreement after understanding the purpose of study and the exposure of radiation.\nHealthy volunteers allowed\nMust have minimum age of 55 Years\nMust have maximum age of 75 Years",
        "exclusion_criteria": "1. proved lung cancer either with or without treatment,\n2. presence of hemoptysis or history of remarkable lung fibrosis,\n3. any other cancer history or\n4. chest CT examination within one year",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "1. relatives of the lung cancer patients;",
                "criterions": [
                    {
                        "exact_snippets": "relatives of the lung cancer patients",
                        "criterion": "relationship to lung cancer patient",
                        "requirement": {
                            "requirement_type": "relationship",
                            "expected_value": "relative"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "relatives of the lung cancer patients",
                        "criterion": "relationship to lung cancer patient",
                        "requirement": {
                            "requirement_type": "relationship",
                            "expected_value": "relative"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "2. age older than 55 years old or age older than the age of onset of lung cancer proband if the family members were less than 55 years old;",
                "criterions": [
                    {
                        "exact_snippets": "age older than 55 years old",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "comparison",
                            "expected_value": {
                                "operator": ">",
                                "value": 55,
                                "unit": "years"
                            }
                        }
                    },
                    {
                        "exact_snippets": "age older than the age of onset of lung cancer proband",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "comparison",
                            "expected_value": "older than the age of onset of lung cancer proband"
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": "age older than 55 years old",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "comparison",
                            "expected_value": {
                                "operator": ">",
                                "value": 55,
                                "unit": "years"
                            }
                        }
                    },
                    {
                        "exact_snippets": "age older than the age of onset of lung cancer proband",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "comparison",
                            "expected_value": "older than the age of onset of lung cancer proband"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "3. compulsory signing the consent agreement after understanding the purpose of study and the exposure of radiation.",
                "criterions": [
                    {
                        "exact_snippets": "compulsory signing the consent agreement",
                        "criterion": "consent agreement",
                        "requirement": {
                            "requirement_type": "signing",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "understanding the purpose of study",
                        "criterion": "understanding of study purpose",
                        "requirement": {
                            "requirement_type": "understanding",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "understanding ... the exposure of radiation",
                        "criterion": "understanding of radiation exposure",
                        "requirement": {
                            "requirement_type": "understanding",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "compulsory signing the consent agreement",
                        "criterion": "consent agreement",
                        "requirement": {
                            "requirement_type": "signing",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "understanding the purpose of study",
                        "criterion": "understanding of study purpose",
                        "requirement": {
                            "requirement_type": "understanding",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "understanding ... the exposure of radiation",
                        "criterion": "understanding of radiation exposure",
                        "requirement": {
                            "requirement_type": "understanding",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 55 Years",
                "criterions": [
                    {
                        "exact_snippets": "minimum age of 55 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 55,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "minimum age of 55 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 55,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have maximum age of 75 Years",
                "criterions": [
                    {
                        "exact_snippets": "maximum age of 75 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 75,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "maximum age of 75 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 75,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "2. presence of hemoptysis or history of remarkable lung fibrosis,",
                "criterions": [
                    {
                        "exact_snippets": "presence of hemoptysis",
                        "criterion": "hemoptysis",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "history of remarkable lung fibrosis",
                        "criterion": "lung fibrosis",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "history of remarkable lung fibrosis",
                        "criterion": "lung fibrosis",
                        "requirement": {
                            "requirement_type": "severity",
                            "expected_value": "remarkable"
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "history of remarkable lung fibrosis",
                                "criterion": "lung fibrosis",
                                "requirement": {
                                    "requirement_type": "history",
                                    "expected_value": true
                                }
                            },
                            {
                                "exact_snippets": "history of remarkable lung fibrosis",
                                "criterion": "lung fibrosis",
                                "requirement": {
                                    "requirement_type": "severity",
                                    "expected_value": "remarkable"
                                }
                            }
                        ]
                    },
                    {
                        "exact_snippets": "presence of hemoptysis",
                        "criterion": "hemoptysis",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "3. any other cancer history or",
                "criterions": [
                    {
                        "exact_snippets": "any other cancer history",
                        "criterion": "cancer history",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "any other cancer history",
                    "criterion": "cancer history",
                    "requirement": {
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "4. chest CT examination within one year",
                "criterions": [
                    {
                        "exact_snippets": "chest CT examination within one year",
                        "criterion": "chest CT examination",
                        "requirement": {
                            "requirement_type": "time frame",
                            "expected_value": "within one year"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "chest CT examination within one year",
                        "criterion": "chest CT examination",
                        "requirement": {
                            "requirement_type": "time frame",
                            "expected_value": "within one year"
                        }
                    }
                ]
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [
        {
            "identified_line": {
                "line": "1. proved lung cancer either with or without treatment,",
                "criterions": [
                    {
                        "exact_snippets": "proved lung cancer",
                        "criterion": "lung cancer",
                        "requirement": {
                            "requirement_type": "confirmation",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "either with or without treatment",
                        "criterion": "treatment status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": [
                                "with treatment",
                                "without treatment"
                            ]
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "proved lung cancer",
                                "criterion": "lung cancer",
                                "requirement": {
                                    "requirement_type": "confirmation",
                                    "expected_value": true
                                }
                            },
                            {
                                "or_criteria": [
                                    {
                                        "exact_snippets": "either with or without treatment",
                                        "criterion": "treatment status",
                                        "requirement": {
                                            "requirement_type": "status",
                                            "expected_value": "with treatment"
                                        }
                                    },
                                    {
                                        "exact_snippets": "either with or without treatment",
                                        "criterion": "treatment status",
                                        "requirement": {
                                            "requirement_type": "status",
                                            "expected_value": "without treatment"
                                        }
                                    }
                                ]
                            }
                        ]
                    }
                ]
            }
        }
    ],
    "failed_miscellaneous": []
}