{
    "info": {
        "nct_id": "NCT02225262",
        "official_title": "Prospective Evaluation of CyberKnife Stereotactic Radiosurgery for Low and Intermediate Risk Prostate Cancer: Emulating Homogenous Dose Distribution",
        "inclusion_criteria": "* Male Age ≥ 21\n* Histologically proven prostate adenocarcinoma\n* Clinical stage T1b-T2b, N0-Nx, M0-Mx (AJCC 6th Edition)\n* PSA ≤ 20 ng/ml\n* Prostate volume ≤ 100 cc\n\nPatients belonging in one of the following risk groups:\n\n* Low:\n\n  * CS T1b-T2a and Gleason 2-6 and PSA ≤ 10\n* Intermediate:\n\n  * CS T2b and Gleason 2-6 and PSA ≤ 10, OR\n  * CS T1b-T2b, and Gleason 2-6 and PSA ≤ 20 ng/ml OR Gleason 7 and PSA ≤ 10 ng/ml\nHealthy volunteers allowed\nMust be MALE\nMust have minimum age of 21 Years",
        "exclusion_criteria": "* Any histology other than adenocarcinoma\n* Age < 21\n* KPS <= 40 <70\n* ECOG Performance Status ≥ 2\n* Patient weight >350 lbs. (table limitation)\n* Prior XRT to prostate or lower pelvis\n* Prior surgery or cryotherapy to prostate\n* Implanted hardware or other material that would prohibit appropriate treatment planning or treatment delivery, in the investigator's opinion\n* Chemotherapy for a malignancy in the last 5 years\n* History of an invasive malignancy (other than this prostate cancer, or basal or squamous skin cancers) in the last 5 years\n* Hormone ablation for 2 months prior to enrollment, or during treatment",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* Male Age ≥ 21",
                "criterions": [
                    {
                        "exact_snippets": "Male",
                        "criterion": "gender",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": "male"
                        }
                    },
                    {
                        "exact_snippets": "Age ≥ 21",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">=",
                                "value": 21,
                                "unit": "years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Male",
                        "criterion": "gender",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": "male"
                        }
                    },
                    {
                        "exact_snippets": "Age ≥ 21",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">=",
                                "value": 21,
                                "unit": "years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Histologically proven prostate adenocarcinoma",
                "criterions": [
                    {
                        "exact_snippets": "Histologically proven prostate adenocarcinoma",
                        "criterion": "prostate adenocarcinoma",
                        "requirement": {
                            "requirement_type": "confirmation method",
                            "expected_value": "histologically proven"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Histologically proven prostate adenocarcinoma",
                        "criterion": "prostate adenocarcinoma",
                        "requirement": {
                            "requirement_type": "confirmation method",
                            "expected_value": "histologically proven"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Clinical stage T1b-T2b, N0-Nx, M0-Mx (AJCC 6th Edition)",
                "criterions": [
                    {
                        "exact_snippets": "Clinical stage T1b-T2b",
                        "criterion": "clinical stage T",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 1,
                                        "unit": "b"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 2,
                                        "unit": "b"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "N0-Nx",
                        "criterion": "clinical stage N",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 0,
                                        "unit": ""
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 0,
                                        "unit": "x"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "M0-Mx",
                        "criterion": "clinical stage M",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 0,
                                        "unit": ""
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 0,
                                        "unit": "x"
                                    }
                                ]
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Clinical stage T1b-T2b",
                        "criterion": "clinical stage T",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 1,
                                        "unit": "b"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 2,
                                        "unit": "b"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "N0-Nx",
                        "criterion": "clinical stage N",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 0,
                                        "unit": ""
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 0,
                                        "unit": "x"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "M0-Mx",
                        "criterion": "clinical stage M",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 0,
                                        "unit": ""
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 0,
                                        "unit": "x"
                                    }
                                ]
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Patients belonging in one of the following risk groups:",
                "criterions": [
                    {
                        "exact_snippets": "Patients belonging in one of the following risk groups",
                        "criterion": "risk group",
                        "requirement": {
                            "requirement_type": "membership",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": "Patients belonging in one of the following risk groups",
                        "criterion": "risk group",
                        "requirement": {
                            "requirement_type": "membership",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Low:",
                "criterions": [
                    {
                        "exact_snippets": "Low",
                        "criterion": "risk level",
                        "requirement": {
                            "requirement_type": "severity",
                            "expected_value": "low"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Low",
                        "criterion": "risk level",
                        "requirement": {
                            "requirement_type": "severity",
                            "expected_value": "low"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* CS T1b-T2a and Gleason 2-6 and PSA ≤ 10",
                "criterions": [
                    {
                        "exact_snippets": "CS T1b-T2a",
                        "criterion": "clinical stage",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 1.1,
                                        "unit": "T"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 2.1,
                                        "unit": "T"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "Gleason 2-6",
                        "criterion": "Gleason score",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 2,
                                        "unit": "N/A"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 6,
                                        "unit": "N/A"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "PSA ≤ 10",
                        "criterion": "PSA level",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": "<=",
                                "value": 10,
                                "unit": "N/A"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "CS T1b-T2a",
                        "criterion": "clinical stage",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 1.1,
                                        "unit": "T"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 2.1,
                                        "unit": "T"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "Gleason 2-6",
                        "criterion": "Gleason score",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 2,
                                        "unit": "N/A"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 6,
                                        "unit": "N/A"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "PSA ≤ 10",
                        "criterion": "PSA level",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": "<=",
                                "value": 10,
                                "unit": "N/A"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Intermediate:",
                "criterions": [
                    {
                        "exact_snippets": "Intermediate",
                        "criterion": "disease stage",
                        "requirement": {
                            "requirement_type": "severity",
                            "expected_value": "Intermediate"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Intermediate",
                        "criterion": "disease stage",
                        "requirement": {
                            "requirement_type": "severity",
                            "expected_value": "Intermediate"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* CS T2b and Gleason 2-6 and PSA ≤ 10, OR",
                "criterions": [
                    {
                        "exact_snippets": "CS T2b",
                        "criterion": "clinical stage",
                        "requirement": {
                            "requirement_type": "stage",
                            "expected_value": "T2b"
                        }
                    },
                    {
                        "exact_snippets": "Gleason 2-6",
                        "criterion": "Gleason score",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 2,
                                        "unit": "N/A"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 6,
                                        "unit": "N/A"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "PSA ≤ 10",
                        "criterion": "PSA level",
                        "requirement": {
                            "requirement_type": "level",
                            "expected_value": {
                                "operator": "<=",
                                "value": 10,
                                "unit": "N/A"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": "CS T2b",
                                "criterion": "clinical stage",
                                "requirement": {
                                    "requirement_type": "stage",
                                    "expected_value": "T2b"
                                }
                            },
                            {
                                "exact_snippets": "Gleason 2-6",
                                "criterion": "Gleason score",
                                "requirement": {
                                    "requirement_type": "range",
                                    "expected_value": {
                                        "comparisons": [
                                            {
                                                "operator": ">=",
                                                "value": 2,
                                                "unit": "N/A"
                                            },
                                            {
                                                "operator": "<=",
                                                "value": 6,
                                                "unit": "N/A"
                                            }
                                        ]
                                    }
                                }
                            },
                            {
                                "exact_snippets": "PSA ≤ 10",
                                "criterion": "PSA level",
                                "requirement": {
                                    "requirement_type": "level",
                                    "expected_value": {
                                        "operator": "<=",
                                        "value": 10,
                                        "unit": "N/A"
                                    }
                                }
                            }
                        ]
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* CS T1b-T2b, and Gleason 2-6 and PSA ≤ 20 ng/ml OR Gleason 7 and PSA ≤ 10 ng/ml",
                "criterions": [
                    {
                        "exact_snippets": "CS T1b-T2b",
                        "criterion": "clinical stage",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 1,
                                        "unit": "b"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 2,
                                        "unit": "b"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "Gleason 2-6",
                        "criterion": "Gleason score",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 2,
                                        "unit": "N/A"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 6,
                                        "unit": "N/A"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "PSA ≤ 20 ng/ml",
                        "criterion": "PSA level",
                        "requirement": {
                            "requirement_type": "level",
                            "expected_value": {
                                "operator": "<=",
                                "value": 20,
                                "unit": "ng/ml"
                            }
                        }
                    },
                    {
                        "exact_snippets": "Gleason 7",
                        "criterion": "Gleason score",
                        "requirement": {
                            "requirement_type": "exact",
                            "expected_value": "7"
                        }
                    },
                    {
                        "exact_snippets": "PSA ≤ 10 ng/ml",
                        "criterion": "PSA level",
                        "requirement": {
                            "requirement_type": "level",
                            "expected_value": {
                                "operator": "<=",
                                "value": 10,
                                "unit": "ng/ml"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "and_criteria": [
                            {
                                "and_criteria": [
                                    {
                                        "exact_snippets": "CS T1b-T2b",
                                        "criterion": "clinical stage",
                                        "requirement": {
                                            "requirement_type": "range",
                                            "expected_value": {
                                                "comparisons": [
                                                    {
                                                        "operator": ">=",
                                                        "value": 1,
                                                        "unit": "b"
                                                    },
                                                    {
                                                        "operator": "<=",
                                                        "value": 2,
                                                        "unit": "b"
                                                    }
                                                ]
                                            }
                                        }
                                    },
                                    {
                                        "exact_snippets": "Gleason 2-6",
                                        "criterion": "Gleason score",
                                        "requirement": {
                                            "requirement_type": "range",
                                            "expected_value": {
                                                "comparisons": [
                                                    {
                                                        "operator": ">=",
                                                        "value": 2,
                                                        "unit": "N/A"
                                                    },
                                                    {
                                                        "operator": "<=",
                                                        "value": 6,
                                                        "unit": "N/A"
                                                    }
                                                ]
                                            }
                                        }
                                    }
                                ]
                            },
                            {
                                "exact_snippets": "PSA ≤ 20 ng/ml",
                                "criterion": "PSA level",
                                "requirement": {
                                    "requirement_type": "level",
                                    "expected_value": {
                                        "operator": "<=",
                                        "value": 20,
                                        "unit": "ng/ml"
                                    }
                                }
                            }
                        ]
                    },
                    {
                        "and_criteria": [
                            {
                                "and_criteria": [
                                    {
                                        "exact_snippets": "CS T1b-T2b",
                                        "criterion": "clinical stage",
                                        "requirement": {
                                            "requirement_type": "range",
                                            "expected_value": {
                                                "comparisons": [
                                                    {
                                                        "operator": ">=",
                                                        "value": 1,
                                                        "unit": "b"
                                                    },
                                                    {
                                                        "operator": "<=",
                                                        "value": 2,
                                                        "unit": "b"
                                                    }
                                                ]
                                            }
                                        }
                                    },
                                    {
                                        "exact_snippets": "Gleason 7",
                                        "criterion": "Gleason score",
                                        "requirement": {
                                            "requirement_type": "exact",
                                            "expected_value": "7"
                                        }
                                    }
                                ]
                            },
                            {
                                "exact_snippets": "PSA ≤ 10 ng/ml",
                                "criterion": "PSA level",
                                "requirement": {
                                    "requirement_type": "level",
                                    "expected_value": {
                                        "operator": "<=",
                                        "value": 10,
                                        "unit": "ng/ml"
                                    }
                                }
                            }
                        ]
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must be MALE",
                "criterions": [
                    {
                        "exact_snippets": "Must be MALE",
                        "criterion": "gender",
                        "requirement": {
                            "requirement_type": "expected_value",
                            "expected_value": "male"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Must be MALE",
                        "criterion": "gender",
                        "requirement": {
                            "requirement_type": "expected_value",
                            "expected_value": "male"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 21 Years",
                "criterions": [
                    {
                        "exact_snippets": "minimum age of 21 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 21,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "minimum age of 21 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 21,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "* Any histology other than adenocarcinoma",
                "criterions": [
                    {
                        "exact_snippets": "histology other than adenocarcinoma",
                        "criterion": "histology",
                        "requirement": {
                            "requirement_type": "type",
                            "expected_value": {
                                "operator": "!=",
                                "value": 1,
                                "unit": "adenocarcinoma"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": "histology other than adenocarcinoma",
                    "criterion": "histology",
                    "requirement": {
                        "requirement_type": "type",
                        "expected_value": {
                            "operator": "!=",
                            "value": 1,
                            "unit": "adenocarcinoma"
                        }
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Age < 21",
                "criterions": [
                    {
                        "exact_snippets": "Age < 21",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": "<",
                                "value": 21,
                                "unit": "years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Age < 21",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": "<",
                                "value": 21,
                                "unit": "years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* KPS <= 40 <70",
                "criterions": [
                    {
                        "exact_snippets": "KPS <= 40 <70",
                        "criterion": "Karnofsky Performance Status (KPS)",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": "<=",
                                        "value": 40,
                                        "unit": "N/A"
                                    },
                                    {
                                        "operator": "<",
                                        "value": 70,
                                        "unit": "N/A"
                                    }
                                ]
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "KPS <= 40 <70",
                        "criterion": "Karnofsky Performance Status (KPS)",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": "<=",
                                        "value": 40,
                                        "unit": "N/A"
                                    },
                                    {
                                        "operator": "<",
                                        "value": 70,
                                        "unit": "N/A"
                                    }
                                ]
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* ECOG Performance Status ≥ 2",
                "criterions": [
                    {
                        "exact_snippets": "ECOG Performance Status ≥ 2",
                        "criterion": "ECOG Performance Status",
                        "requirement": {
                            "requirement_type": "severity",
                            "expected_value": {
                                "operator": ">=",
                                "value": 2,
                                "unit": "N/A"
                            }
                        }
                    }
                ]
            },
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                "not_criteria": {
                    "exact_snippets": "ECOG Performance Status ≥ 2",
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                        "requirement_type": "severity",
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                            "operator": ">=",
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                        }
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Patient weight >350 lbs. (table limitation)",
                "criterions": [
                    {
                        "exact_snippets": "Patient weight >350 lbs.",
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                            "requirement_type": "value",
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                                "operator": ">",
                                "value": 350,
                                "unit": "lbs"
                            }
                        }
                    }
                ]
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                    {
                        "exact_snippets": "Patient weight >350 lbs.",
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                                "operator": ">",
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                        }
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                ]
            }
        },
        {
            "identified_line": {
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                    {
                        "exact_snippets": "Prior XRT to prostate",
                        "criterion": "prior XRT to prostate",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "Prior XRT to ... lower pelvis",
                        "criterion": "prior XRT to lower pelvis",
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                            "requirement_type": "presence",
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                        }
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                        "exact_snippets": "Prior XRT to prostate",
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                    {
                        "exact_snippets": "Prior XRT to ... lower pelvis",
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                        }
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                ]
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        {
            "identified_line": {
                "line": "* Prior surgery or cryotherapy to prostate",
                "criterions": [
                    {
                        "exact_snippets": "Prior surgery ... to prostate",
                        "criterion": "prostate surgery",
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                            "requirement_type": "history",
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                        }
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                    {
                        "exact_snippets": "Prior ... cryotherapy to prostate",
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                    {
                        "exact_snippets": "Prior surgery ... to prostate",
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                    },
                    {
                        "exact_snippets": "Prior ... cryotherapy to prostate",
                        "criterion": "prostate cryotherapy",
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                            "requirement_type": "history",
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        },
        {
            "identified_line": {
                "line": "* Implanted hardware or other material that would prohibit appropriate treatment planning or treatment delivery, in the investigator's opinion",
                "criterions": [
                    {
                        "exact_snippets": "Implanted hardware or other material that would prohibit appropriate treatment planning or treatment delivery",
                        "criterion": "implanted hardware or other material",
                        "requirement": {
                            "requirement_type": "impact on treatment",
                            "expected_value": "prohibit appropriate treatment planning or treatment delivery"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Implanted hardware or other material that would prohibit appropriate treatment planning or treatment delivery",
                        "criterion": "implanted hardware or other material",
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                            "requirement_type": "impact on treatment",
                            "expected_value": "prohibit appropriate treatment planning or treatment delivery"
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                    },
                    {
                        "exact_snippets": "in the investigator's opinion",
                        "criterion": "investigator's opinion",
                        "requirement": {
                            "requirement_type": "agreement",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Chemotherapy for a malignancy in the last 5 years",
                "criterions": [
                    {
                        "exact_snippets": "Chemotherapy for a malignancy in the last 5 years",
                        "criterion": "chemotherapy for a malignancy",
                        "requirement": {
                            "requirement_type": "time frame",
                            "expected_value": {
                                "operator": "<=",
                                "value": 5,
                                "unit": "years"
                            }
                        }
                    }
                ]
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            "logical_structure": {
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                    "exact_snippets": "Chemotherapy for a malignancy in the last 5 years",
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                            "operator": "<=",
                            "value": 5,
                            "unit": "years"
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                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* History of an invasive malignancy (other than this prostate cancer, or basal or squamous skin cancers) in the last 5 years",
                "criterions": [
                    {
                        "exact_snippets": "History of an invasive malignancy (other than this prostate cancer, or basal or squamous skin cancers) in the last 5 years",
                        "criterion": "invasive malignancy",
                        "requirement": {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "History of an invasive malignancy (other than this prostate cancer, or basal or squamous skin cancers) in the last 5 years",
                        "criterion": "invasive malignancy",
                        "requirement": {
                            "requirement_type": "time frame",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": "<=",
                                        "value": 5,
                                        "unit": "years"
                                    }
                                ]
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "and_criteria": [
                            {
                                "not_criteria": {
                                    "and_criteria": [
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                                            "exact_snippets": "History of an invasive malignancy (other than this prostate cancer, or basal or squamous skin cancers) in the last 5 years",
                                            "criterion": "invasive malignancy",
                                            "requirement": {
                                                "requirement_type": "history",
                                                "expected_value": true
                                            }
                                        },
                                        {
                                            "exact_snippets": "History of an invasive malignancy (other than this prostate cancer, or basal or squamous skin cancers) in the last 5 years",
                                            "criterion": "invasive malignancy",
                                            "requirement": {
                                                "requirement_type": "time frame",
                                                "expected_value": {
                                                    "comparisons": [
                                                        {
                                                            "operator": "<=",
                                                            "value": 5,
                                                            "unit": "years"
                                                        }
                                                    ]
                                                }
                                            }
                                        }
                                    ]
                                }
                            },
                            {
                                "exact_snippets": "History of an invasive malignancy (other than this prostate cancer, or basal or squamous skin cancers) in the last 5 years",
                                "criterion": "invasive malignancy",
                                "requirement": {
                                    "requirement_type": "type",
                                    "expected_value": [
                                        "prostate cancer",
                                        "basal skin cancer",
                                        "squamous skin cancer"
                                    ]
                                }
                            }
                        ]
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Hormone ablation for 2 months prior to enrollment, or during treatment",
                "criterions": [
                    {
                        "exact_snippets": "Hormone ablation for 2 months prior to enrollment",
                        "criterion": "hormone ablation",
                        "requirement": {
                            "requirement_type": "duration",
                            "expected_value": {
                                "operator": ">=",
                                "value": 2,
                                "unit": "months"
                            }
                        }
                    },
                    {
                        "exact_snippets": "Hormone ablation for 2 months prior to enrollment",
                        "criterion": "hormone ablation",
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                            "requirement_type": "timing",
                            "expected_value": "prior to enrollment"
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                    },
                    {
                        "exact_snippets": "Hormone ablation ... during treatment",
                        "criterion": "hormone ablation",
                        "requirement": {
                            "requirement_type": "timing",
                            "expected_value": "during treatment"
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
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                        "and_criteria": [
                            {
                                "exact_snippets": "Hormone ablation for 2 months prior to enrollment",
                                "criterion": "hormone ablation",
                                "requirement": {
                                    "requirement_type": "duration",
                                    "expected_value": {
                                        "operator": ">=",
                                        "value": 2,
                                        "unit": "months"
                                    }
                                }
                            },
                            {
                                "exact_snippets": "Hormone ablation for 2 months prior to enrollment",
                                "criterion": "hormone ablation",
                                "requirement": {
                                    "requirement_type": "timing",
                                    "expected_value": "prior to enrollment"
                                }
                            }
                        ]
                    },
                    {
                        "exact_snippets": "Hormone ablation ... during treatment",
                        "criterion": "hormone ablation",
                        "requirement": {
                            "requirement_type": "timing",
                            "expected_value": "during treatment"
                        }
                    }
                ]
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [
        {
            "identified_line": {
                "line": "* PSA ≤ 20 ng/ml",
                "criterions": [
                    {
                        "exact_snippets": "PSA ≤ 20 ng/ml",
                        "criterion": "PSA",
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                            "requirement_type": "level",
                            "expected_value": {
                                "operator": "<=",
                                "value": 20,
                                "unit": "ng/ml"
                            }
                        }
                    }
                ]
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            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "PSA \u0010 20 ng/ml",
                        "criterion": "PSA",
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                            "requirement_type": "level",
                            "expected_value": {
                                "operator": "<=",
                                "value": 20,
                                "unit": "ng/ml"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Prostate volume ≤ 100 cc",
                "criterions": [
                    {
                        "exact_snippets": "Prostate volume ≤ 100 cc",
                        "criterion": "prostate volume",
                        "requirement": {
                            "requirement_type": "size",
                            "expected_value": {
                                "operator": "<=",
                                "value": 100,
                                "unit": "cc"
                            }
                        }
                    }
                ]
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            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Prostate volume \u0010 100 cc",
                        "criterion": "prostate volume",
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                            "requirement_type": "size",
                            "expected_value": {
                                "operator": "<=",
                                "value": 100,
                                "unit": "cc"
                            }
                        }
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                ]
            }
        }
    ],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}