{
    "info": {
        "nct_id": "NCT01048320",
        "official_title": "A Phase I Study of Gemcitabine Plus Oxaliplatin in Combination With Imatinib Mesylate (Glivec) in Patients With Gemcitabine-refractory Advanced Adenocarcinoma of the Pancreas",
        "inclusion_criteria": "* age > 18 years\n* gemcitabine-refractory, histologically confirmed pancreatic cancer (progression during or within 6 months of first-line treatment)\n* locally advanced or metastatic disease with measurable or non-measurable disease\n* life expectancy of greater than 10 weeks\n* prior treatment with investigational therapies including EGFR and VEGF antagonists is allowed when administered>4 weeks prior to start of therapy\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* any serious uncontrolled medical condition\n* prior radiation treatment is not allowed\n* no prior chemotherapy within the previous 4 weeks\n* known peripheral neuropathy > CTCAE v 3.0 grade 1; absence of the deep tendon reflexes as the sole neurological abnormality does not render the patient ineligible\n* known brain metastases\n* lack of physical integrity of the upper GI tract, malabsorption syndrome, or inability to take oral medication\n* fertile women (<2 years after last menstruation) and men of childbearing potential not willing to use effective contraception\n* pregnancy or breast feeding",
        "miscellaneous_criteria": ""
    },
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                                "unit": "Years"
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