{
    "info": {
        "nct_id": "NCT00758173",
        "official_title": "A Population Based Study of Genetic Predisposition and Gene-Environment Interactions in Prostate Cancer in East Anglia, Trent and West Midlands",
        "inclusion_criteria": "Healthy volunteers allowed\nMust be MALE\nMust have minimum age of 18 Years\nMust have maximum age of 74 Years",
        "exclusion_criteria": "",
        "miscellaneous_criteria": "DISEASE CHARACTERISTICS:\n\n* Diagnosis of prostate cancer within the past 5 years\n* Identified through the cancer registry serving any of the following geographic regions of the United Kingdom:\n\n  * East Anglia\n  * Trent\n  * West Midlands\n\nPATIENT CHARACTERISTICS:\n\n* Identified by the patient's general practitioner as fit to contact for this study\n* No serious mental illness or retardation\n\nPRIOR CONCURRENT THERAPY:\n\n* Not specified"
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must be MALE",
                "criterions": [
                    {
                        "exact_snippets": "Must be MALE",
                        "criterion": "gender",
                        "requirement": {
                            "requirement_type": "expected_value",
                            "expected_value": "male"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Must be MALE",
                        "criterion": "gender",
                        "requirement": {
                            "requirement_type": "expected_value",
                            "expected_value": "male"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 18 Years",
                "criterions": [
                    {
                        "exact_snippets": "minimum age of 18 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "minimum age of 18 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have maximum age of 74 Years",
                "criterions": [
                    {
                        "exact_snippets": "maximum age of 74 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 74,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "maximum age of 74 Years",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 74,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [],
    "miscellaneous_lines": [
        {
            "identified_line": {
                "line": "* Diagnosis of prostate cancer within the past 5 years",
                "criterions": [
                    {
                        "exact_snippets": "Diagnosis of prostate cancer",
                        "criterion": "prostate cancer diagnosis",
                        "requirement": {
                            "requirement_type": "timeframe",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": "<=",
                                        "value": 5,
                                        "unit": "years"
                                    }
                                ]
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Diagnosis of prostate cancer",
                        "criterion": "prostate cancer diagnosis",
                        "requirement": {
                            "requirement_type": "timeframe",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": "<=",
                                        "value": 5,
                                        "unit": "years"
                                    }
                                ]
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Identified through the cancer registry serving any of the following geographic regions of the United Kingdom:",
                "criterions": [
                    {
                        "exact_snippets": "Identified through the cancer registry serving any of the following geographic regions of the United Kingdom",
                        "criterion": "geographic region",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": [
                                "United Kingdom"
                            ]
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Identified through the cancer registry serving any of the following geographic regions of the United Kingdom",
                        "criterion": "geographic region",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": [
                                "United Kingdom"
                            ]
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* East Anglia",
                "criterions": [
                    {
                        "exact_snippets": "East Anglia",
                        "criterion": "geographic location",
                        "requirement": {
                            "requirement_type": "location",
                            "expected_value": "East Anglia"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "East Anglia",
                        "criterion": "geographic location",
                        "requirement": {
                            "requirement_type": "location",
                            "expected_value": "East Anglia"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Trent",
                "criterions": [
                    {
                        "exact_snippets": "Trent",
                        "criterion": "Trent",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Trent",
                        "criterion": "Trent",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* West Midlands",
                "criterions": [
                    {
                        "exact_snippets": "West Midlands",
                        "criterion": "geographic location",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": "West Midlands"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "West Midlands",
                        "criterion": "geographic location",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": "West Midlands"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Identified by the patient's general practitioner as fit to contact for this study",
                "criterions": [
                    {
                        "exact_snippets": "Identified by the patient's general practitioner as fit to contact for this study",
                        "criterion": "fitness for contact",
                        "requirement": {
                            "requirement_type": "assessment",
                            "expected_value": "fit to contact"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Identified by the patient's general practitioner as fit to contact for this study",
                        "criterion": "fitness for contact",
                        "requirement": {
                            "requirement_type": "assessment",
                            "expected_value": "fit to contact"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* No serious mental illness or retardation",
                "criterions": [
                    {
                        "exact_snippets": "No serious mental illness",
                        "criterion": "mental illness",
                        "requirement": {
                            "requirement_type": "severity",
                            "expected_value": "not serious"
                        }
                    },
                    {
                        "exact_snippets": "No ... retardation",
                        "criterion": "retardation",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "No serious mental illness",
                        "criterion": "mental illness",
                        "requirement": {
                            "requirement_type": "severity",
                            "expected_value": "not serious"
                        }
                    },
                    {
                        "exact_snippets": "No ... retardation",
                        "criterion": "retardation",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "PRIOR CONCURRENT THERAPY:",
                "criterions": [
                    {
                        "exact_snippets": "PRIOR CONCURRENT THERAPY",
                        "criterion": "prior concurrent therapy",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "PRIOR CONCURRENT THERAPY",
                        "criterion": "prior concurrent therapy",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "DISEASE CHARACTERISTICS:",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        },
        {
            "identified_line": {
                "line": "PATIENT CHARACTERISTICS:",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        },
        {
            "identified_line": {
                "line": "* Not specified",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        }
    ],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}