{
    "info": {
        "nct_id": "NCT00006994",
        "official_title": "S9908, A Double-Blind, Placebo-Controlled Trial To Study The Efficacy And Safety Of L-Glutamine (In AES0014 Delivery Vehicle) Upon Radiation Therapy-Induced Oral Mucositis In Head and Neck Cancer Patients, Phase III",
        "inclusion_criteria": "Healthy volunteers allowed\nMust have minimum age of 18 Years\nMust have maximum age of 90 Years",
        "exclusion_criteria": "",
        "miscellaneous_criteria": "DISEASE CHARACTERISTICS:\n\n* Newly diagnosed, previously untreated squamous cell cancer of the oral cavity or oropharynx (T1-T4, any N, M0)\n* Must be scheduled to receive high-dose radiotherapy\n* Not concurrently receiving or planning to receive treatment on any other Southwest Oncology Group protocol\n\nPATIENT CHARACTERISTICS:\n\nAge:\n\n* 18 to 90\n\nPerformance status:\n\n* Zubrod 0-2\n\nLife expectancy:\n\n* Not specified\n\nHematopoietic:\n\n* Not specified\n\nHepatic:\n\n* Not specified\n\nRenal:\n\n* Not specified\n\nOther:\n\n* No other malignancy within the past 5 years except adequately treated basal cell or squamous cell skin cancer, carcinoma in situ of the cervix, or stage I or II cancer currently in complete remission\n* Not pregnant or nursing\n* Fertile patients must use effective contraception\n\nPRIOR CONCURRENT THERAPY:\n\nBiologic therapy:\n\n* Not specified\n\nChemotherapy:\n\n* No prior chemotherapy\n* Concurrent cisplatin, carboplatin, or fluorouracil allowed\n* No other concurrent chemotherapy during study and for at least 3 weeks after study radiotherapy\n\nEndocrine therapy:\n\n* Not specified\n\nRadiotherapy:\n\n* See Disease Characteristics\n\nSurgery:\n\n* Not specified\n\nOther:\n\n* No concurrent amifostine during and for 2 weeks after study radiotherapy"
    },
    "inclusion_lines": [
        {
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                "criterions": [
                    {
                        "exact_snippets": "Healthy volunteers allowed",
                        "criterion": "volunteer health status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    }
                ]
            },
            "logical_structure": {
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                        }
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                ]
            }
        },
        {
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                "line": "Must have minimum age of 18 Years",
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                    {
                        "exact_snippets": "minimum age of 18 Years",
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                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
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                    {
                        "exact_snippets": "minimum age of 18 Years",
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                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have maximum age of 90 Years",
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                    {
                        "exact_snippets": "maximum age of 90 Years",
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                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 90,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
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                        "exact_snippets": "maximum age of 90 Years",
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                            "expected_value": {
                                "operator": "<=",
                                "value": 90,
                                "unit": "Years"
                            }
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [],
    "miscellaneous_lines": [
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                        "criterion": "diagnosis status",
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                            "requirement_type": "status",
                            "expected_value": "newly diagnosed"
                        }
                    },
                    {
                        "exact_snippets": "previously untreated",
                        "criterion": "treatment history",
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                        }
                    },
                    {
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                        "criterion": "cancer type",
                        "requirement": {
                            "requirement_type": "type",
                            "expected_value": "squamous cell cancer"
                        }
                    },
                    {
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                        "criterion": "cancer location",
                        "requirement": {
                            "requirement_type": "location",
                            "expected_value": [
                                "oral cavity",
                                "oropharynx"
                            ]
                        }
                    },
                    {
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                        "criterion": "tumor stage",
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                            "requirement_type": "stage",
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                                    {
                                        "operator": ">=",
                                        "value": 1,
                                        "unit": "T"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 4,
                                        "unit": "T"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "any N",
                        "criterion": "nodal involvement",
                        "requirement": {
                            "requirement_type": "involvement",
                            "expected_value": "any N"
                        }
                    },
                    {
                        "exact_snippets": "M0",
                        "criterion": "metastasis",
                        "requirement": {
                            "requirement_type": "metastasis",
                            "expected_value": "M0"
                        }
                    }
                ]
            },
            "logical_structure": {
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                    {
                        "exact_snippets": "Newly diagnosed",
                        "criterion": "diagnosis status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": "newly diagnosed"
                        }
                    },
                    {
                        "exact_snippets": "previously untreated",
                        "criterion": "treatment history",
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                            "requirement_type": "treatment",
                            "expected_value": "untreated"
                        }
                    },
                    {
                        "exact_snippets": "squamous cell cancer",
                        "criterion": "cancer type",
                        "requirement": {
                            "requirement_type": "type",
                            "expected_value": "squamous cell cancer"
                        }
                    },
                    {
                        "exact_snippets": "oral cavity or oropharynx",
                        "criterion": "cancer location",
                        "requirement": {
                            "requirement_type": "location",
                            "expected_value": [
                                "oral cavity",
                                "oropharynx"
                            ]
                        }
                    },
                    {
                        "exact_snippets": "T1-T4",
                        "criterion": "tumor stage",
                        "requirement": {
                            "requirement_type": "stage",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 1,
                                        "unit": "T"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 4,
                                        "unit": "T"
                                    }
                                ]
                            }
                        }
                    },
                    {
                        "exact_snippets": "any N",
                        "criterion": "nodal involvement",
                        "requirement": {
                            "requirement_type": "involvement",
                            "expected_value": "any N"
                        }
                    },
                    {
                        "exact_snippets": "M0",
                        "criterion": "metastasis",
                        "requirement": {
                            "requirement_type": "metastasis",
                            "expected_value": "M0"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Must be scheduled to receive high-dose radiotherapy",
                "criterions": [
                    {
                        "exact_snippets": "scheduled to receive high-dose radiotherapy",
                        "criterion": "radiotherapy",
                        "requirement": {
                            "requirement_type": "dose",
                            "expected_value": "high"
                        }
                    },
                    {
                        "exact_snippets": "scheduled to receive high-dose radiotherapy",
                        "criterion": "radiotherapy",
                        "requirement": {
                            "requirement_type": "schedule",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "scheduled to receive high-dose radiotherapy",
                        "criterion": "radiotherapy",
                        "requirement": {
                            "requirement_type": "dose",
                            "expected_value": "high"
                        }
                    },
                    {
                        "exact_snippets": "scheduled to receive high-dose radiotherapy",
                        "criterion": "radiotherapy",
                        "requirement": {
                            "requirement_type": "schedule",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Not concurrently receiving or planning to receive treatment on any other Southwest Oncology Group protocol",
                "criterions": [
                    {
                        "exact_snippets": "Not concurrently receiving ... treatment on any other Southwest Oncology Group protocol",
                        "criterion": "concurrent treatment on Southwest Oncology Group protocol",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "planning to receive treatment on any other Southwest Oncology Group protocol",
                        "criterion": "planned treatment on Southwest Oncology Group protocol",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Not concurrently receiving ... treatment on any other Southwest Oncology Group protocol",
                        "criterion": "concurrent treatment on Southwest Oncology Group protocol",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "planning to receive treatment on any other Southwest Oncology Group protocol",
                        "criterion": "planned treatment on Southwest Oncology Group protocol",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Age:",
                "criterions": [
                    {
                        "exact_snippets": "Age:",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "N/A",
                            "expected_value": "N/A"
                        }
                    }
                ]
            },
            "logical_structure": {
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                    {
                        "exact_snippets": "Age:",
                        "criterion": "age",
                        "requirement": {
                            "requirement_type": "N/A",
                            "expected_value": "N/A"
                        }
                    }
                ]
            }
        },
        {
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                        "exact_snippets": "18 to 90",
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                            "requirement_type": "range",
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                                        "operator": ">=",
                                        "value": 18,
                                        "unit": "years"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 90,
                                        "unit": "years"
                                    }
                                ]
                            }
                        }
                    }
                ]
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                            "requirement_type": "range",
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                                    {
                                        "operator": ">=",
                                        "value": 18,
                                        "unit": "years"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 90,
                                        "unit": "years"
                                    }
                                ]
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                        }
                    }
                ]
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        },
        {
            "identified_line": {
                "line": "Performance status:",
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                        "exact_snippets": "Performance status:",
                        "criterion": "performance status",
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                            "requirement_type": "N/A",
                            "expected_value": "N/A"
                        }
                    }
                ]
            },
            "logical_structure": {
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                        "exact_snippets": "Performance status:",
                        "criterion": "performance status",
                        "requirement": {
                            "requirement_type": "N/A",
                            "expected_value": "N/A"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Zubrod 0-2",
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                    {
                        "exact_snippets": "Zubrod 0-2",
                        "criterion": "Zubrod performance status",
                        "requirement": {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 0,
                                        "unit": "N/A"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 2,
                                        "unit": "N/A"
                                    }
                                ]
                            }
                        }
                    }
                ]
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            "logical_structure": {
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                        "exact_snippets": "Zubrod 0-2",
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                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 0,
                                        "unit": "N/A"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 2,
                                        "unit": "N/A"
                                    }
                                ]
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Life expectancy:",
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                    {
                        "exact_snippets": "Life expectancy",
                        "criterion": "life expectancy",
                        "requirement": {
                            "requirement_type": "N/A",
                            "expected_value": "N/A"
                        }
                    }
                ]
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            "logical_structure": {
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                        "exact_snippets": "Life expectancy",
                        "criterion": "life expectancy",
                        "requirement": {
                            "requirement_type": "N/A",
                            "expected_value": "N/A"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Hematopoietic:",
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                    {
                        "exact_snippets": "Hematopoietic:",
                        "criterion": "hematopoietic system",
                        "requirement": {
                            "requirement_type": "N/A",
                            "expected_value": "N/A"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Hematopoietic:",
                        "criterion": "hematopoietic system",
                        "requirement": {
                            "requirement_type": "N/A",
                            "expected_value": "N/A"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Hepatic:",
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                    {
                        "exact_snippets": "Hepatic",
                        "criterion": "hepatic function",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
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                        "exact_snippets": "Hepatic",
                        "criterion": "hepatic function",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Renal:",
                "criterions": [
                    {
                        "exact_snippets": "Renal:",
                        "criterion": "renal function",
                        "requirement": {
                            "requirement_type": "N/A",
                            "expected_value": "N/A"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Renal:",
                        "criterion": "renal function",
                        "requirement": {
                            "requirement_type": "N/A",
                            "expected_value": "N/A"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* No other malignancy within the past 5 years except adequately treated basal cell or squamous cell skin cancer, carcinoma in situ of the cervix, or stage I or II cancer currently in complete remission",
                "criterions": [
                    {
                        "exact_snippets": "No other malignancy within the past 5 years",
                        "criterion": "other malignancy",
                        "requirement": {
                            "requirement_type": "time frame",
                            "expected_value": {
                                "operator": "<=",
                                "value": 5,
                                "unit": "years"
                            }
                        }
                    },
                    {
                        "exact_snippets": "No other malignancy within the past 5 years",
                        "criterion": "other malignancy",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "except adequately treated basal cell or squamous cell skin cancer",
                        "criterion": "adequately treated basal cell or squamous cell skin cancer",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "except ... carcinoma in situ of the cervix",
                        "criterion": "carcinoma in situ of the cervix",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    },
                    {
                        "exact_snippets": "except ... stage I or II cancer currently in complete remission",
                        "criterion": "stage I or II cancer",
                        "requirement": {
                            "requirement_type": "remission status",
                            "expected_value": "complete remission"
                        }
                    }
                ]
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            "logical_structure": {
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                        "not_criteria": {
                            "and_criteria": [
                                {
                                    "and_criteria": [
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                                            "exact_snippets": "No other malignancy within the past 5 years",
                                            "criterion": "other malignancy",
                                            "requirement": {
                                                "requirement_type": "time frame",
                                                "expected_value": {
                                                    "operator": "<=",
                                                    "value": 5,
                                                    "unit": "years"
                                                }
                                            }
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                                        {
                                            "exact_snippets": "No other malignancy within the past 5 years",
                                            "criterion": "other malignancy",
                                            "requirement": {
                                                "requirement_type": "presence",
                                                "expected_value": false
                                            }
                                        }
                                    ]
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                    {
                        "or_criteria": [
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                                "exact_snippets": "except adequately treated basal cell or squamous cell skin cancer",
                                "criterion": "adequately treated basal cell or squamous cell skin cancer",
                                "requirement": {
                                    "requirement_type": "presence",
                                    "expected_value": true
                                }
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                            {
                                "exact_snippets": "except ... carcinoma in situ of the cervix",
                                "criterion": "carcinoma in situ of the cervix",
                                "requirement": {
                                    "requirement_type": "presence",
                                    "expected_value": true
                                }
                            },
                            {
                                "exact_snippets": "except ... stage I or II cancer currently in complete remission",
                                "criterion": "stage I or II cancer",
                                "requirement": {
                                    "requirement_type": "remission status",
                                    "expected_value": "complete remission"
                                }
                            }
                        ]
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* No prior chemotherapy",
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                    {
                        "exact_snippets": "No prior chemotherapy",
                        "criterion": "prior chemotherapy",
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                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            },
            "logical_structure": {
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                        "exact_snippets": "No prior chemotherapy",
                        "criterion": "prior chemotherapy",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* No other concurrent chemotherapy during study and for at least 3 weeks after study radiotherapy",
                "criterions": [
                    {
                        "exact_snippets": "No other concurrent chemotherapy during study",
                        "criterion": "concurrent chemotherapy",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "for at least 3 weeks after study radiotherapy",
                        "criterion": "chemotherapy after radiotherapy",
                        "requirement": {
                            "requirement_type": "time period",
                            "expected_value": {
                                "operator": "<",
                                "value": 3,
                                "unit": "weeks"
                            }
                        }
                    }
                ]
            },
            "logical_structure": {
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                    {
                        "exact_snippets": "No other concurrent chemotherapy during study",
                        "criterion": "concurrent chemotherapy",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "for at least 3 weeks after study radiotherapy",
                        "criterion": "chemotherapy after radiotherapy",
                        "requirement": {
                            "requirement_type": "time period",
                            "expected_value": {
                                "operator": "<",
                                "value": 3,
                                "unit": "weeks"
                            }
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Endocrine therapy:",
                "criterions": [
                    {
                        "exact_snippets": "Endocrine therapy",
                        "criterion": "endocrine therapy",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Endocrine therapy",
                        "criterion": "endocrine therapy",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Radiotherapy:",
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                    {
                        "exact_snippets": "Radiotherapy",
                        "criterion": "radiotherapy",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
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                    {
                        "exact_snippets": "Radiotherapy",
                        "criterion": "radiotherapy",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* See Disease Characteristics",
                "criterions": [
                    {
                        "exact_snippets": "Disease Characteristics",
                        "criterion": "disease characteristics",
                        "requirement": {
                            "requirement_type": "N/A",
                            "expected_value": "refer to disease characteristics section"
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Disease Characteristics",
                        "criterion": "disease characteristics",
                        "requirement": {
                            "requirement_type": "N/A",
                            "expected_value": "refer to disease characteristics section"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Surgery:",
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                    {
                        "exact_snippets": "Surgery",
                        "criterion": "surgery",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": "Surgery",
                        "criterion": "surgery",
                        "requirement": {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            }
        },
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            "identified_line": {
                "line": "* No concurrent amifostine during and for 2 weeks after study radiotherapy",
                "criterions": [
                    {
                        "exact_snippets": "No concurrent amifostine during and for 2 weeks after study radiotherapy",
                        "criterion": "amifostine use",
                        "requirement": {
                            "requirement_type": "concurrency",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "No concurrent amifostine during and for 2 weeks after study radiotherapy",
                        "criterion": "amifostine use",
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                            "requirement_type": "duration",
                            "expected_value": "during and for 2 weeks after study radiotherapy"
                        }
                    }
                ]
            },
            "logical_structure": {
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                        "exact_snippets": "No concurrent amifostine during and for 2 weeks after study radiotherapy",
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                            "requirement_type": "concurrency",
                            "expected_value": false
                        }
                    },
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                        "exact_snippets": "No concurrent amifostine during and for 2 weeks after study radiotherapy",
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                            "requirement_type": "duration",
                            "expected_value": "during and for 2 weeks after study radiotherapy"
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "DISEASE CHARACTERISTICS:",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        },
        {
            "identified_line": {
                "line": "PATIENT CHARACTERISTICS:",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        },
        {
            "identified_line": {
                "line": "* Not specified",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        },
        {
            "identified_line": {
                "line": "* Not specified",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        },
        {
            "identified_line": {
                "line": "* Not specified",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        },
        {
            "identified_line": {
                "line": "* Not specified",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        },
        {
            "identified_line": {
                "line": "Other:",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        },
        {
            "identified_line": {
                "line": "* Not pregnant or nursing",
                "criterions": [
                    {
                        "exact_snippets": "Not pregnant",
                        "criterion": "pregnancy status",
                        "requirement": {
                            "requirement_type": "status",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "not ... nursing",
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                            "requirement_type": "status",
                            "expected_value": false
                        }
                    }
                ]
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                        "exact_snippets": "Not pregnant",
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                            "requirement_type": "status",
                            "expected_value": false
                        }
                    },
                    {
                        "exact_snippets": "not ... nursing",
                        "criterion": "nursing status",
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                            "requirement_type": "status",
                            "expected_value": false
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Not specified",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        },
        {
            "identified_line": {
                "line": "* Not specified",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        },
        {
            "identified_line": {
                "line": "* Not specified",
                "criterions": []
            },
            "logical_structure": {
                "and_criteria": []
            }
        },
        {
            "identified_line": {
                "line": "Other:",
                "criterions": []
            },
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                "and_criteria": []
            }
        }
    ],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": [
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                "line": "* Fertile patients must use effective contraception",
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                    {
                        "exact_snippets": "Fertile patients",
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                            "requirement_type": "status",
                            "expected_value": "fertile"
                        }
                    },
                    {
                        "exact_snippets": "must use effective contraception",
                        "criterion": "contraception use",
                        "requirement": {
                            "requirement_type": "necessity",
                            "expected_value": true
                        }
                    }
                ]
            },
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                "exact_snippets": "failed",
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            }
        },
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            "identified_line": {
                "line": "PRIOR CONCURRENT THERAPY:",
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                    {
                        "exact_snippets": "PRIOR CONCURRENT THERAPY",
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                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
            "logical_structure": {
                "exact_snippets": "failed",
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                }
            }
        },
        {
            "identified_line": {
                "line": "Biologic therapy:",
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                    {
                        "exact_snippets": "Biologic therapy",
                        "criterion": "biologic therapy",
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                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    }
                ]
            },
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                "exact_snippets": "failed",
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                    "requirement_type": "failed",
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        },
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            "identified_line": {
                "line": "Chemotherapy:",
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                        "exact_snippets": "Chemotherapy",
                        "criterion": "chemotherapy",
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                            "expected_value": true
                        }
                    }
                ]
            },
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                "exact_snippets": "failed",
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                    "requirement_type": "failed",
                    "expected_value": "failed"
                }
            }
        },
        {
            "identified_line": {
                "line": "* Concurrent cisplatin, carboplatin, or fluorouracil allowed",
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                    {
                        "exact_snippets": "Concurrent cisplatin, carboplatin, or fluorouracil allowed",
                        "criterion": "concurrent chemotherapy",
                        "requirement": {
                            "requirement_type": "allowed agents",
                            "expected_value": [
                                "cisplatin",
                                "carboplatin",
                                "fluorouracil"
                            ]
                        }
                    }
                ]
            },
            "logical_structure": {
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                            "expected_value": "cisplatin"
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                    {
                        "exact_snippets": "Concurrent cisplatin, carboplatin, or fluorouracil allowed",
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                            "requirement_type": "allowed agents",
                            "expected_value": "carboplatin"
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                        "exact_snippets": "Concurrent cisplatin, carboplatin, or fluorouracil allowed",
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                            "requirement_type": "allowed agents",
                            "expected_value": "fluorouracil"
                        }
                    }
                ]
            }
        }
    ]
}