{
    "info": {
        "nct_id": "NCT06339372",
        "official_title": "Perioperative Supplementation With Immunonutrition and Its Impact on Surgical Outcome and Pain in Oral Cavity or Mandibular Tumours",
        "inclusion_criteria": "* Age between 18 and 60 years.\n* Both sexes.\n* American Society of Anesthesiologists (ASA) physical status I or II .\n* Patient undergoing mandibular or oral cavity tumour resection.\n* Body mass index (BMI) between 18.5-24.9.\n* Patient with serum albumen above 3 gm.\n* Patient with written valid consent\nHealthy volunteers allowed\nMust have minimum age of 18 Years\nMust have maximum age of 60 Years",
        "exclusion_criteria": "* Patient refusal and uncooperative patients.\n* Patient ASA III or IV.\n* Age more than 60 or less than 18.\n* Serum albumen less than 3.\n* Pre-existing severe malnourishment.\n* Allergy to test drugs.\n* Patients on tranquilizers, hypnotics, sedatives and other psychotropic patient on steroids and NSAID.",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Age between 18 and 60 years.",
            "criterions": [
                {
                    "exact_snippets": "Age between 18 and 60 years.",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 18,
                                        "unit": "years"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 60,
                                        "unit": "years"
                                    }
                                ]
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Both sexes.",
            "criterions": [
                {
                    "exact_snippets": "Both sexes.",
                    "criterion": "sex",
                    "requirements": [
                        {
                            "requirement_type": "allowed",
                            "expected_value": [
                                "male",
                                "female"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "* American Society of Anesthesiologists (ASA) physical status I or II .",
            "criterions": [
                {
                    "exact_snippets": "American Society of Anesthesiologists (ASA) physical status I or II",
                    "criterion": "ASA physical status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": [
                                "I",
                                "II"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patient undergoing mandibular or oral cavity tumour resection.",
            "criterions": [
                {
                    "exact_snippets": "mandibular or oral cavity tumour resection",
                    "criterion": "tumour resection",
                    "requirements": [
                        {
                            "requirement_type": "location",
                            "expected_value": [
                                "mandibular",
                                "oral cavity"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Body mass index (BMI) between 18.5-24.9.",
            "criterions": [
                {
                    "exact_snippets": "Body mass index (BMI) between 18.5-24.9.",
                    "criterion": "body mass index (BMI)",
                    "requirements": [
                        {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 18.5,
                                        "unit": ""
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 24.9,
                                        "unit": ""
                                    }
                                ]
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patient with serum albumen above 3 gm.",
            "criterions": [
                {
                    "exact_snippets": "serum albumen above 3 gm",
                    "criterion": "serum albumen",
                    "requirements": [
                        {
                            "requirement_type": "level",
                            "expected_value": {
                                "operator": ">",
                                "value": 3,
                                "unit": "gm"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patient with written valid consent",
            "criterions": [
                {
                    "exact_snippets": "written valid consent",
                    "criterion": "consent",
                    "requirements": [
                        {
                            "requirement_type": "validity",
                            "expected_value": true
                        },
                        {
                            "requirement_type": "form",
                            "expected_value": "written"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have maximum age of 60 Years",
            "criterions": [
                {
                    "exact_snippets": "maximum age of 60 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 60,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Patient refusal and uncooperative patients.",
            "criterions": [
                {
                    "exact_snippets": "Patient refusal",
                    "criterion": "patient consent",
                    "requirements": [
                        {
                            "requirement_type": "consent",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "uncooperative patients",
                    "criterion": "patient cooperation",
                    "requirements": [
                        {
                            "requirement_type": "cooperation",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patient ASA III or IV.",
            "criterions": [
                {
                    "exact_snippets": "Patient ASA III or IV",
                    "criterion": "ASA classification",
                    "requirements": [
                        {
                            "requirement_type": "classification",
                            "expected_value": [
                                "III",
                                "IV"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Age more than 60 or less than 18.",
            "criterions": [
                {
                    "exact_snippets": "Age more than 60",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": ">",
                                "value": 60,
                                "unit": "years"
                            }
                        }
                    ]
                },
                {
                    "exact_snippets": "less than 18",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": "<",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Serum albumen less than 3.",
            "criterions": [
                {
                    "exact_snippets": "Serum albumen less than 3",
                    "criterion": "serum albumen",
                    "requirements": [
                        {
                            "requirement_type": "level",
                            "expected_value": {
                                "operator": "<",
                                "value": 3,
                                "unit": "N/A"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Pre-existing severe malnourishment.",
            "criterions": [
                {
                    "exact_snippets": "Pre-existing severe malnourishment",
                    "criterion": "malnourishment",
                    "requirements": [
                        {
                            "requirement_type": "severity",
                            "expected_value": "severe"
                        },
                        {
                            "requirement_type": "pre-existing",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Allergy to test drugs.",
            "criterions": [
                {
                    "exact_snippets": "Allergy to test drugs",
                    "criterion": "allergy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patients on tranquilizers, hypnotics, sedatives and other psychotropic patient on steroids and NSAID.",
            "criterions": [
                {
                    "exact_snippets": "Patients on tranquilizers",
                    "criterion": "use of tranquilizers",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "hypnotics",
                    "criterion": "use of hypnotics",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "sedatives",
                    "criterion": "use of sedatives",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "other psychotropic",
                    "criterion": "use of other psychotropic drugs",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "patient on steroids",
                    "criterion": "use of steroids",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "NSAID",
                    "criterion": "use of NSAIDs",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}