{
    "info": {
        "nct_id": "NCT06287294",
        "official_title": "An Investigation Into Taste Problems Associated With Xerostomia in Patients With Advanced Cancer",
        "inclusion_criteria": "* 18 years of age\n* Diagnosis of locally advanced or metastatic cancer\n* Referred to palliative care/oncology services\n* Dry mouth rated 'moderate' or worse over previous 2-week period\n* Taste problems rated 'moderate' or worse over previous 2-week period\n* Good understanding of English\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* Cognitive impairment (unable to provide consent / complete questionnaire)\n* Dry mouth precedes cancer diagnosis.\n* Taste problems precedes cancer diagnosis.\n* Head and neck surgery\n* Head and neck radiotherapy\n* Salivary gland disorders (e.g., Sjogren's Syndrome)\n* In the 'Deteriorating' or 'Terminal' Phase of illness",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* 18 years of age",
            "criterions": [
                {
                    "exact_snippets": "18 years of age",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "N/A",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Diagnosis of locally advanced or metastatic cancer",
            "criterions": [
                {
                    "exact_snippets": "Diagnosis of locally advanced or metastatic cancer",
                    "criterion": "cancer",
                    "requirements": [
                        {
                            "requirement_type": "diagnosis",
                            "expected_value": "locally advanced or metastatic"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Referred to palliative care/oncology services",
            "criterions": [
                {
                    "exact_snippets": "Referred to palliative care",
                    "criterion": "palliative care referral",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "Referred to ... oncology services",
                    "criterion": "oncology services referral",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Dry mouth rated 'moderate' or worse over previous 2-week period",
            "criterions": [
                {
                    "exact_snippets": "Dry mouth rated 'moderate' or worse over previous 2-week period",
                    "criterion": "dry mouth",
                    "requirements": [
                        {
                            "requirement_type": "severity",
                            "expected_value": {
                                "operator": ">=",
                                "value": 3,
                                "unit": "scale"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Taste problems rated 'moderate' or worse over previous 2-week period",
            "criterions": [
                {
                    "exact_snippets": "Taste problems rated 'moderate' or worse",
                    "criterion": "taste problems",
                    "requirements": [
                        {
                            "requirement_type": "severity",
                            "expected_value": {
                                "operator": ">=",
                                "value": 3,
                                "unit": "N/A"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Good understanding of English",
            "criterions": [
                {
                    "exact_snippets": "Good understanding of English",
                    "criterion": "English language comprehension",
                    "requirements": [
                        {
                            "requirement_type": "proficiency",
                            "expected_value": "good"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Cognitive impairment (unable to provide consent / complete questionnaire)",
            "criterions": [
                {
                    "exact_snippets": "Cognitive impairment (unable to provide consent / complete questionnaire)",
                    "criterion": "cognitive impairment",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Dry mouth precedes cancer diagnosis.",
            "criterions": [
                {
                    "exact_snippets": "Dry mouth precedes cancer diagnosis",
                    "criterion": "dry mouth",
                    "requirements": [
                        {
                            "requirement_type": "temporal relationship",
                            "expected_value": "precedes cancer diagnosis"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Taste problems precedes cancer diagnosis.",
            "criterions": [
                {
                    "exact_snippets": "Taste problems precedes cancer diagnosis",
                    "criterion": "taste problems",
                    "requirements": [
                        {
                            "requirement_type": "temporal relationship",
                            "expected_value": "precedes cancer diagnosis"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Head and neck surgery",
            "criterions": [
                {
                    "exact_snippets": "Head and neck surgery",
                    "criterion": "head and neck surgery",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Head and neck radiotherapy",
            "criterions": [
                {
                    "exact_snippets": "Head and neck radiotherapy",
                    "criterion": "radiotherapy",
                    "requirements": [
                        {
                            "requirement_type": "location",
                            "expected_value": "head and neck"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Salivary gland disorders (e.g., Sjogren's Syndrome)",
            "criterions": [
                {
                    "exact_snippets": "Salivary gland disorders (e.g., Sjogren's Syndrome)",
                    "criterion": "salivary gland disorders",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* In the 'Deteriorating' or 'Terminal' Phase of illness",
            "criterions": [
                {
                    "exact_snippets": "'Deteriorating' or 'Terminal' Phase of illness",
                    "criterion": "phase of illness",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": [
                                "Deteriorating",
                                "Terminal"
                            ]
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}