{
    "info": {
        "nct_id": "NCT06282562",
        "official_title": "FeelFit: High-intensity Interval Training to Improve Self-reported Physical Fitness in Brain Tumor Patients: a Randomized Controlled Trial",
        "inclusion_criteria": "* reduced self-reported physical fitness;\n* minimum age of 18 years;\n* diagnosed with a primary brain tumor;\n* stable disease, i.e. no signs of radiological or clinical tumor progression;\n* no oncological treatment for at least two months prior to inclusion;\n* able to speak, read and write in Dutch.\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* Karnofsky Performance Score < 70;\n* already participated in a HIIT program < 1 month prior;\n* contraindication of exercise.",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* reduced self-reported physical fitness;",
            "criterions": [
                {
                    "exact_snippets": "reduced self-reported physical fitness",
                    "criterion": "physical fitness",
                    "requirements": [
                        {
                            "requirement_type": "self-reported level",
                            "expected_value": "reduced"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* minimum age of 18 years;",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "N/A",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* diagnosed with a primary brain tumor;",
            "criterions": [
                {
                    "exact_snippets": "diagnosed with a primary brain tumor",
                    "criterion": "primary brain tumor",
                    "requirements": [
                        {
                            "requirement_type": "diagnosis",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* stable disease, i.e. no signs of radiological or clinical tumor progression;",
            "criterions": [
                {
                    "exact_snippets": "stable disease, i.e. no signs of radiological or clinical tumor progression",
                    "criterion": "tumor progression",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* no oncological treatment for at least two months prior to inclusion;",
            "criterions": [
                {
                    "exact_snippets": "no oncological treatment for at least two months prior to inclusion",
                    "criterion": "oncological treatment",
                    "requirements": [
                        {
                            "requirement_type": "time since last treatment",
                            "expected_value": {
                                "operator": ">=",
                                "value": 2,
                                "unit": "months"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* able to speak, read and write in Dutch.",
            "criterions": [
                {
                    "exact_snippets": "able to speak ... in Dutch",
                    "criterion": "language proficiency",
                    "requirements": [
                        {
                            "requirement_type": "language",
                            "expected_value": "Dutch"
                        },
                        {
                            "requirement_type": "skill",
                            "expected_value": "speaking"
                        }
                    ]
                },
                {
                    "exact_snippets": "able to ... read ... in Dutch",
                    "criterion": "language proficiency",
                    "requirements": [
                        {
                            "requirement_type": "language",
                            "expected_value": "Dutch"
                        },
                        {
                            "requirement_type": "skill",
                            "expected_value": "reading"
                        }
                    ]
                },
                {
                    "exact_snippets": "able to ... write in Dutch",
                    "criterion": "language proficiency",
                    "requirements": [
                        {
                            "requirement_type": "language",
                            "expected_value": "Dutch"
                        },
                        {
                            "requirement_type": "skill",
                            "expected_value": "writing"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "healthy volunteers",
                    "requirements": [
                        {
                            "requirement_type": "participation",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Karnofsky Performance Score < 70;",
            "criterions": [
                {
                    "exact_snippets": "Karnofsky Performance Score < 70",
                    "criterion": "Karnofsky Performance Score",
                    "requirements": [
                        {
                            "requirement_type": "score",
                            "expected_value": {
                                "operator": "<",
                                "value": 70,
                                "unit": "N/A"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* already participated in a HIIT program < 1 month prior;",
            "criterions": [
                {
                    "exact_snippets": "already participated in a HIIT program < 1 month prior",
                    "criterion": "HIIT program participation",
                    "requirements": [
                        {
                            "requirement_type": "time since participation",
                            "expected_value": {
                                "operator": "<",
                                "value": 1,
                                "unit": "month"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* contraindication of exercise.",
            "criterions": [
                {
                    "exact_snippets": "contraindication of exercise",
                    "criterion": "exercise",
                    "requirements": [
                        {
                            "requirement_type": "contraindication",
                            "expected_value": true
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}