{
    "info": {
        "nct_id": "NCT05520294",
        "official_title": "Evaluating the Effects of Cannabis Use and Circulating Cannabinoids on Tumor Infiltrating Lymphocytes in Malignant Melanoma",
        "inclusion_criteria": "* Biopsy proven melanoma, any stage\n\n  * Biopsy obtained within 4 weeks of anticipated enrollment\n  * Patients >21 years old\n  * Report no cannabis use in the last year or chronic cannabis use (at least weekly use for 3 months or more)\nMust have minimum age of 21 Years\nMust have maximum age of 100 Years",
        "exclusion_criteria": "* Patients unwilling or unable to provide informed consent",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Biopsy proven melanoma, any stage",
            "criterions": [
                {
                    "exact_snippets": "Biopsy proven melanoma",
                    "criterion": "melanoma",
                    "requirements": [
                        {
                            "requirement_type": "diagnosis",
                            "expected_value": "biopsy proven"
                        }
                    ]
                },
                {
                    "exact_snippets": "any stage",
                    "criterion": "melanoma stage",
                    "requirements": [
                        {
                            "requirement_type": "stage",
                            "expected_value": "any"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Biopsy obtained within 4 weeks of anticipated enrollment",
            "criterions": [
                {
                    "exact_snippets": "Biopsy obtained within 4 weeks of anticipated enrollment",
                    "criterion": "biopsy",
                    "requirements": [
                        {
                            "requirement_type": "timing",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": "<=",
                                        "value": 4,
                                        "unit": "weeks"
                                    }
                                ]
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patients >21 years old",
            "criterions": [
                {
                    "exact_snippets": "Patients >21 years old",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "age",
                            "expected_value": {
                                "operator": ">",
                                "value": 21,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Report no cannabis use in the last year or chronic cannabis use (at least weekly use for 3 months or more)",
            "criterions": [
                {
                    "exact_snippets": "Report no cannabis use in the last year",
                    "criterion": "cannabis use",
                    "requirements": [
                        {
                            "requirement_type": "timeframe",
                            "expected_value": "last year"
                        },
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "chronic cannabis use (at least weekly use for 3 months or more)",
                    "criterion": "chronic cannabis use",
                    "requirements": [
                        {
                            "requirement_type": "frequency",
                            "expected_value": "at least weekly"
                        },
                        {
                            "requirement_type": "duration",
                            "expected_value": {
                                "operator": ">=",
                                "value": 3,
                                "unit": "months"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 21 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 21 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 21,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have maximum age of 100 Years",
            "criterions": [
                {
                    "exact_snippets": "maximum age of 100 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 100,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Patients unwilling or unable to provide informed consent",
            "criterions": [
                {
                    "exact_snippets": "unwilling or unable to provide informed consent",
                    "criterion": "informed consent",
                    "requirements": [
                        {
                            "requirement_type": "ability and willingness",
                            "expected_value": true
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}