{
    "info": {
        "nct_id": "NCT05123391",
        "official_title": "Technical Feasibility of a Randomized Pilot Study of Radiosurgery for the Treatment of Non-metastatic Prostate Cancer",
        "inclusion_criteria": "* Histology confirmed prostate cancer\n* Disease confined to the pelvis by imaging CT (CT scan of chest, abdomen and pelvis and bone scan or prostate specific membrane antigen positron emission tomography (PET-PSMA) if required according to local guidelines)\n* Eastern Cooperative Oncology Group (ECOG) performance 0-1\n* Eligible for curative radiotherapy\nHealthy volunteers allowed\nMust be MALE\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* Metastasis beyond the pelvis\n* Poor performance ECOG 2-4\n* Cannot follow directions to prepare for simulation (bladder filling and rectal emptying)",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Histology confirmed prostate cancer",
            "criterions": [
                {
                    "exact_snippets": "Histology confirmed prostate cancer",
                    "criterion": "prostate cancer",
                    "requirements": [
                        {
                            "requirement_type": "confirmation method",
                            "expected_value": "histology"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Disease confined to the pelvis by imaging CT (CT scan of chest, abdomen and pelvis and bone scan or prostate specific membrane antigen positron emission tomography (PET-PSMA) if required according to local guidelines)",
            "criterions": [
                {
                    "exact_snippets": "Disease confined to the pelvis by imaging CT",
                    "criterion": "disease location",
                    "requirements": [
                        {
                            "requirement_type": "location",
                            "expected_value": "pelvis"
                        }
                    ]
                },
                {
                    "exact_snippets": "CT scan of chest, abdomen and pelvis",
                    "criterion": "imaging requirement",
                    "requirements": [
                        {
                            "requirement_type": "imaging type",
                            "expected_value": "CT scan"
                        },
                        {
                            "requirement_type": "imaging areas",
                            "expected_value": [
                                "chest",
                                "abdomen",
                                "pelvis"
                            ]
                        }
                    ]
                },
                {
                    "exact_snippets": "bone scan or prostate specific membrane antigen positron emission tomography (PET-PSMA) if required according to local guidelines",
                    "criterion": "additional imaging",
                    "requirements": [
                        {
                            "requirement_type": "imaging type",
                            "expected_value": [
                                "bone scan",
                                "PET-PSMA"
                            ]
                        },
                        {
                            "requirement_type": "condition",
                            "expected_value": "if required according to local guidelines"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Eastern Cooperative Oncology Group (ECOG) performance 0-1",
            "criterions": [
                {
                    "exact_snippets": "Eastern Cooperative Oncology Group (ECOG) performance 0-1",
                    "criterion": "ECOG performance status",
                    "requirements": [
                        {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 0,
                                        "unit": "N/A"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 1,
                                        "unit": "N/A"
                                    }
                                ]
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Eligible for curative radiotherapy",
            "criterions": [
                {
                    "exact_snippets": "Eligible for curative radiotherapy",
                    "criterion": "curative radiotherapy eligibility",
                    "requirements": [
                        {
                            "requirement_type": "eligibility",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must be MALE",
            "criterions": [
                {
                    "exact_snippets": "MALE",
                    "criterion": "gender",
                    "requirements": [
                        {
                            "requirement_type": "expected_value",
                            "expected_value": "male"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Metastasis beyond the pelvis",
            "criterions": [
                {
                    "exact_snippets": "Metastasis beyond the pelvis",
                    "criterion": "metastasis",
                    "requirements": [
                        {
                            "requirement_type": "location",
                            "expected_value": "beyond the pelvis"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Poor performance ECOG 2-4",
            "criterions": [
                {
                    "exact_snippets": "Poor performance ECOG 2-4",
                    "criterion": "ECOG performance status",
                    "requirements": [
                        {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 2,
                                        "unit": "N/A"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 4,
                                        "unit": "N/A"
                                    }
                                ]
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Cannot follow directions to prepare for simulation (bladder filling and rectal emptying)",
            "criterions": [
                {
                    "exact_snippets": "Cannot follow directions to prepare for simulation (bladder filling and rectal emptying)",
                    "criterion": "ability to follow directions for simulation preparation",
                    "requirements": [
                        {
                            "requirement_type": "ability",
                            "expected_value": false
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}