{
    "info": {
        "nct_id": "NCT04735991",
        "official_title": "A Real-world Clinical Study Evaluating the Quality of Life in Family Members of Colorectal Cancer Patients Based on a Whole Course Chronic Disease Management System for Cancer Patients' Family",
        "inclusion_criteria": "* (1) Subject: The main family members caring for patients are ≥18 and ≤65 years old;\n* (2) Family members of patients who can understand the purpose of the study, voluntarily participate and sign an informed consent form, and are willing to complete follow-up as required by the protocol;\n* (3) Family members of colorectal cancer patients who need to receive adjuvant chemotherapy XELOX regimen within 6 months after initial diagnosis of high-risk stage II or stage III\nHealthy volunteers allowed\nMust have minimum age of 18 Years\nMust have maximum age of 65 Years",
        "exclusion_criteria": "* (1) Patient life expectancy is less than 3 months\n* (2) Family members of patients cannot use electronic mobile products\n* (3) The family of the patient has a history of malignant tumors or other serious diseases\n* (4) Family members of patients are considered unsuitable by the researcher",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* (1) Subject: The main family members caring for patients are ≥18 and ≤65 years old;",
            "criterions": [
                {
                    "exact_snippets": "main family members caring for patients are ≥18 and ≤65 years old",
                    "criterion": "age of main family members",
                    "requirements": [
                        {
                            "requirement_type": "age range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 18,
                                        "unit": "years"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 65,
                                        "unit": "years"
                                    }
                                ]
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* (2) Family members of patients who can understand the purpose of the study, voluntarily participate and sign an informed consent form, and are willing to complete follow-up as required by the protocol;",
            "criterions": [
                {
                    "exact_snippets": "Family members of patients",
                    "criterion": "relationship to patient",
                    "requirements": [
                        {
                            "requirement_type": "relationship",
                            "expected_value": "family member"
                        }
                    ]
                },
                {
                    "exact_snippets": "can understand the purpose of the study",
                    "criterion": "understanding of study purpose",
                    "requirements": [
                        {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "voluntarily participate",
                    "criterion": "voluntary participation",
                    "requirements": [
                        {
                            "requirement_type": "willingness",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "sign an informed consent form",
                    "criterion": "informed consent",
                    "requirements": [
                        {
                            "requirement_type": "signed",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "willing to complete follow-up as required by the protocol",
                    "criterion": "follow-up completion",
                    "requirements": [
                        {
                            "requirement_type": "willingness",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* (3) Family members of colorectal cancer patients who need to receive adjuvant chemotherapy XELOX regimen within 6 months after initial diagnosis of high-risk stage II or stage III",
            "criterions": [
                {
                    "exact_snippets": "Family members of colorectal cancer patients",
                    "criterion": "family member of colorectal cancer patient",
                    "requirements": [
                        {
                            "requirement_type": "relationship",
                            "expected_value": "family member"
                        }
                    ]
                },
                {
                    "exact_snippets": "need to receive adjuvant chemotherapy XELOX regimen",
                    "criterion": "adjuvant chemotherapy XELOX regimen",
                    "requirements": [
                        {
                            "requirement_type": "necessity",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "within 6 months after initial diagnosis",
                    "criterion": "time since initial diagnosis",
                    "requirements": [
                        {
                            "requirement_type": "time frame",
                            "expected_value": {
                                "operator": "<=",
                                "value": 6,
                                "unit": "months"
                            }
                        }
                    ]
                },
                {
                    "exact_snippets": "high-risk stage II or stage III",
                    "criterion": "cancer stage",
                    "requirements": [
                        {
                            "requirement_type": "stage",
                            "expected_value": [
                                "high-risk stage II",
                                "stage III"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have maximum age of 65 Years",
            "criterions": [
                {
                    "exact_snippets": "maximum age of 65 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 65,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* (1) Patient life expectancy is less than 3 months",
            "criterions": [
                {
                    "exact_snippets": "Patient life expectancy is less than 3 months",
                    "criterion": "life expectancy",
                    "requirements": [
                        {
                            "requirement_type": "duration",
                            "expected_value": {
                                "operator": "<",
                                "value": 3,
                                "unit": "months"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* (2) Family members of patients cannot use electronic mobile products",
            "criterions": [
                {
                    "exact_snippets": "Family members of patients cannot use electronic mobile products",
                    "criterion": "family members' use of electronic mobile products",
                    "requirements": [
                        {
                            "requirement_type": "usage",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* (3) The family of the patient has a history of malignant tumors or other serious diseases",
            "criterions": [
                {
                    "exact_snippets": "The family of the patient has a history of malignant tumors",
                    "criterion": "family history of malignant tumors",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "The family of the patient has a history of ... other serious diseases",
                    "criterion": "family history of other serious diseases",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* (4) Family members of patients are considered unsuitable by the researcher",
            "criterions": [
                {
                    "exact_snippets": "Family members of patients",
                    "criterion": "family member status",
                    "requirements": [
                        {
                            "requirement_type": "suitability",
                            "expected_value": false
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}