{
    "info": {
        "nct_id": "NCT04322331",
        "official_title": "The Different Transcriptional Characterization Of The Tumor Immune Microenvironment of Luminal A Breast Cancer With Different Lymph Node Metastasas Status",
        "inclusion_criteria": "* invasive breast cancer with Luminal A type;T1 with positive lymph node or T2/T3 with negative lymph node\nHealthy volunteers allowed\nMust be FEMALE",
        "exclusion_criteria": "* Missing specimen",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* invasive breast cancer with Luminal A type;T1 with positive lymph node or T2/T3 with negative lymph node",
            "criterions": [
                {
                    "exact_snippets": "invasive breast cancer",
                    "criterion": "breast cancer",
                    "requirements": [
                        {
                            "requirement_type": "type",
                            "expected_value": "invasive"
                        }
                    ]
                },
                {
                    "exact_snippets": "Luminal A type",
                    "criterion": "breast cancer subtype",
                    "requirements": [
                        {
                            "requirement_type": "subtype",
                            "expected_value": "Luminal A"
                        }
                    ]
                },
                {
                    "exact_snippets": "T1 with positive lymph node",
                    "criterion": "tumor stage and lymph node status",
                    "requirements": [
                        {
                            "requirement_type": "tumor stage",
                            "expected_value": "T1"
                        },
                        {
                            "requirement_type": "lymph node status",
                            "expected_value": "positive"
                        }
                    ]
                },
                {
                    "exact_snippets": "T2/T3 with negative lymph node",
                    "criterion": "tumor stage and lymph node status",
                    "requirements": [
                        {
                            "requirement_type": "tumor stage",
                            "expected_value": [
                                "T2",
                                "T3"
                            ]
                        },
                        {
                            "requirement_type": "lymph node status",
                            "expected_value": "negative"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must be FEMALE",
            "criterions": [
                {
                    "exact_snippets": "Must be FEMALE",
                    "criterion": "gender",
                    "requirements": [
                        {
                            "requirement_type": "expected_value",
                            "expected_value": "female"
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Missing specimen",
            "criterions": [
                {
                    "exact_snippets": "Missing specimen",
                    "criterion": "specimen",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}