{
    "info": {
        "nct_id": "NCT03857620",
        "official_title": "Improving Surgical Care and Outcomes in Older Cancer Patients Through Implementation of an Efficient Pre-Surgical Toolkit (OPTI-Surg)",
        "inclusion_criteria": "* Patients must have known or suspected cancer diagnosis and have one of the following cancer-directed operations planned:\n\n  * Gastrectomy\n  * Colectomy\n  * Proctectomy\n  * Esophagectomy\n  * Pancreatectomy\n  * Hepatectomy\n  * Total cystectomy\n  * Partial or total nephrectomy\n  * Lung lobectomy/pneumonectomy\n* Patients with known metastatic disease with a plan for curative intent resection are eligible (e.g. curative liver resection for metastatic colorectal cancer).\n* Patients with double primaries undergoing planned curative operation for both are eligible (e.g. synchronous colon cancers undergoing colectomy to treat both).\n* Patients must be able to speak and complete questionnaires in English.\nHealthy volunteers allowed\nMust have minimum age of 70 Years",
        "exclusion_criteria": "* Patients undergoing emergent surgery are not eligible.\n* Patients under active treatment such as chemotherapy, targeted therapy, immunotherapy, radiation treatment, etc. for second primary, are not eligible.\n* Patients with second primary are not eligible.\n* Patients with known metastatic disease who are undergoing palliative resection are not eligible.\n* Patients with psychiatric illness or other mental impairment that would preclude their ability to give informed consent or to participate in the prehabilitation program are not eligible.",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Patients must have known or suspected cancer diagnosis and have one of the following cancer-directed operations planned:",
            "criterions": [
                {
                    "exact_snippets": "known or suspected cancer diagnosis",
                    "criterion": "cancer diagnosis",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "one of the following cancer-directed operations planned",
                    "criterion": "cancer-directed operations",
                    "requirements": [
                        {
                            "requirement_type": "planned",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Gastrectomy",
            "criterions": [
                {
                    "exact_snippets": "Gastrectomy",
                    "criterion": "gastrectomy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Colectomy",
            "criterions": [
                {
                    "exact_snippets": "Colectomy",
                    "criterion": "colectomy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Proctectomy",
            "criterions": [
                {
                    "exact_snippets": "Proctectomy",
                    "criterion": "proctectomy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Esophagectomy",
            "criterions": [
                {
                    "exact_snippets": "Esophagectomy",
                    "criterion": "esophagectomy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Pancreatectomy",
            "criterions": [
                {
                    "exact_snippets": "Pancreatectomy",
                    "criterion": "pancreatectomy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Hepatectomy",
            "criterions": [
                {
                    "exact_snippets": "Hepatectomy",
                    "criterion": "hepatectomy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Total cystectomy",
            "criterions": [
                {
                    "exact_snippets": "Total cystectomy",
                    "criterion": "total cystectomy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Partial or total nephrectomy",
            "criterions": [
                {
                    "exact_snippets": "Partial or total nephrectomy",
                    "criterion": "nephrectomy",
                    "requirements": [
                        {
                            "requirement_type": "type",
                            "expected_value": [
                                "partial",
                                "total"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Lung lobectomy/pneumonectomy",
            "criterions": [
                {
                    "exact_snippets": "Lung lobectomy/pneumonectomy",
                    "criterion": "lung surgery",
                    "requirements": [
                        {
                            "requirement_type": "type",
                            "expected_value": [
                                "lobectomy",
                                "pneumonectomy"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patients with known metastatic disease with a plan for curative intent resection are eligible (e.g. curative liver resection for metastatic colorectal cancer).",
            "criterions": [
                {
                    "exact_snippets": "known metastatic disease",
                    "criterion": "metastatic disease",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "plan for curative intent resection",
                    "criterion": "curative intent resection plan",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patients with double primaries undergoing planned curative operation for both are eligible (e.g. synchronous colon cancers undergoing colectomy to treat both).",
            "criterions": [
                {
                    "exact_snippets": "Patients with double primaries",
                    "criterion": "double primaries",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "undergoing planned curative operation for both",
                    "criterion": "planned curative operation",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "planned"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patients must be able to speak and complete questionnaires in English.",
            "criterions": [
                {
                    "exact_snippets": "Patients must be able to speak ... in English.",
                    "criterion": "language ability",
                    "requirements": [
                        {
                            "requirement_type": "language",
                            "expected_value": "English"
                        }
                    ]
                },
                {
                    "exact_snippets": "Patients must be able to ... complete questionnaires in English.",
                    "criterion": "questionnaire completion ability",
                    "requirements": [
                        {
                            "requirement_type": "language",
                            "expected_value": "English"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 70 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 70 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 70,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Patients undergoing emergent surgery are not eligible.",
            "criterions": [
                {
                    "exact_snippets": "Patients undergoing emergent surgery are not eligible.",
                    "criterion": "emergent surgery",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patients under active treatment such as chemotherapy, targeted therapy, immunotherapy, radiation treatment, etc. for second primary, are not eligible.",
            "criterions": [
                {
                    "exact_snippets": "Patients under active treatment such as chemotherapy",
                    "criterion": "active chemotherapy treatment",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "Patients under active treatment such as ... targeted therapy",
                    "criterion": "active targeted therapy treatment",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "Patients under active treatment such as ... immunotherapy",
                    "criterion": "active immunotherapy treatment",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "Patients under active treatment such as ... radiation treatment",
                    "criterion": "active radiation treatment",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "for second primary",
                    "criterion": "second primary cancer",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patients with second primary are not eligible.",
            "criterions": [
                {
                    "exact_snippets": "Patients with second primary are not eligible.",
                    "criterion": "second primary",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patients with known metastatic disease who are undergoing palliative resection are not eligible.",
            "criterions": [
                {
                    "exact_snippets": "Patients with known metastatic disease",
                    "criterion": "metastatic disease",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "undergoing palliative resection",
                    "criterion": "palliative resection",
                    "requirements": [
                        {
                            "requirement_type": "undergoing",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Patients with psychiatric illness or other mental impairment that would preclude their ability to give informed consent or to participate in the prehabilitation program are not eligible.",
            "criterions": [
                {
                    "exact_snippets": "psychiatric illness",
                    "criterion": "psychiatric illness",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "mental impairment",
                    "criterion": "mental impairment",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                },
                {
                    "exact_snippets": "ability to give informed consent",
                    "criterion": "ability to give informed consent",
                    "requirements": [
                        {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "ability ... to participate in the prehabilitation program",
                    "criterion": "ability to participate in the prehabilitation program",
                    "requirements": [
                        {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}