{
    "info": {
        "nct_id": "NCT03721562",
        "official_title": "Antibiotic Resistance in Global Pediatric Oncology Centers",
        "inclusion_criteria": "* Pediatric (0-18 years of age) patients having a bacteria isolated from a sterile site (blood, cerebrospinal fluid, body fluid) or urine positive for a Gram-negative bacteria nonsusceptible to at least 1 of the following: third generation cephalosporin, fourth generation cephalosporin or carbapenem OR screening positive for carbapenemase or extended spectrum beta lactamase (ESBL) production.\nHealthy volunteers allowed\nMust have maximum age of 18 Years",
        "exclusion_criteria": "* Repeated isolation of the same organism from the same patient within the study period.",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Pediatric (0-18 years of age) patients having a bacteria isolated from a sterile site (blood, cerebrospinal fluid, body fluid) or urine positive for a Gram-negative bacteria nonsusceptible to at least 1 of the following: third generation cephalosporin, fourth generation cephalosporin or carbapenem OR screening positive for carbapenemase or extended spectrum beta lactamase (ESBL) production.",
            "criterions": [
                {
                    "exact_snippets": "Pediatric (0-18 years of age)",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 0,
                                        "unit": "years"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 18,
                                        "unit": "years"
                                    }
                                ]
                            }
                        }
                    ]
                },
                {
                    "exact_snippets": "bacteria isolated from a sterile site (blood, cerebrospinal fluid, body fluid)",
                    "criterion": "bacteria isolation from sterile site",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "urine positive for a Gram-negative bacteria",
                    "criterion": "Gram-negative bacteria in urine",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "nonsusceptible to at least 1 of the following: third generation cephalosporin, fourth generation cephalosporin or carbapenem",
                    "criterion": "antibiotic nonsusceptibility",
                    "requirements": [
                        {
                            "requirement_type": "nonsusceptibility",
                            "expected_value": [
                                "third generation cephalosporin",
                                "fourth generation cephalosporin",
                                "carbapenem"
                            ]
                        }
                    ]
                },
                {
                    "exact_snippets": "screening positive for carbapenemase",
                    "criterion": "carbapenemase production",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "screening positive for ... extended spectrum beta lactamase (ESBL) production",
                    "criterion": "extended spectrum beta lactamase (ESBL) production",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have maximum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "maximum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Repeated isolation of the same organism from the same patient within the study period.",
            "criterions": [
                {
                    "exact_snippets": "Repeated isolation of the same organism from the same patient",
                    "criterion": "isolation of the same organism",
                    "requirements": [
                        {
                            "requirement_type": "frequency",
                            "expected_value": "repeated"
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}