{
    "info": {
        "nct_id": "NCT02682082",
        "official_title": "A Randomize Double-Blind Control Trial Study Comparing Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis W/Wo Bupivacaine In Patient Being Treated Palliatively For Pancreatic Cancer",
        "inclusion_criteria": "* Confirmed malignant pancreatic lesion involving the pancreatic genu, body, or tail\n* Abdominal or back pain considered to be potentially related to the tumor\n\n  * New onset pain (<3 months)\n  * Constant\n  * Centrally located\n  * With or without irradiation to the back\n  * No obvious other source of pain based on history and physical examination by the attending endosonographer\n* No possibility of surgical management\n* Signed, informed consent\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* Allergy to bupivicaine\n* Age < 18 years\n* Inability or unwillingness to give informed consent",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* Confirmed malignant pancreatic lesion involving the pancreatic genu, body, or tail",
            "criterions": [
                {
                    "exact_snippets": "Confirmed malignant pancreatic lesion",
                    "criterion": "malignant pancreatic lesion",
                    "requirements": [
                        {
                            "requirement_type": "confirmation",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "involving the pancreatic genu, body, or tail",
                    "criterion": "location of pancreatic lesion",
                    "requirements": [
                        {
                            "requirement_type": "location",
                            "expected_value": [
                                "pancreatic genu",
                                "pancreatic body",
                                "pancreatic tail"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Abdominal or back pain considered to be potentially related to the tumor",
            "criterions": [
                {
                    "exact_snippets": "Abdominal ... pain",
                    "criterion": "abdominal pain",
                    "requirements": [
                        {
                            "requirement_type": "relation to tumor",
                            "expected_value": "potentially related"
                        }
                    ]
                },
                {
                    "exact_snippets": "back pain",
                    "criterion": "back pain",
                    "requirements": [
                        {
                            "requirement_type": "relation to tumor",
                            "expected_value": "potentially related"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* New onset pain (<3 months)",
            "criterions": [
                {
                    "exact_snippets": "New onset pain (<3 months)",
                    "criterion": "pain onset",
                    "requirements": [
                        {
                            "requirement_type": "duration",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": "<",
                                        "value": 3,
                                        "unit": "months"
                                    }
                                ]
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Constant",
            "criterions": [
                {
                    "exact_snippets": "Constant",
                    "criterion": "constant",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Centrally located",
            "criterions": [
                {
                    "exact_snippets": "Centrally located",
                    "criterion": "tumor location",
                    "requirements": [
                        {
                            "requirement_type": "location",
                            "expected_value": "centrally located"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* With or without irradiation to the back",
            "criterions": [
                {
                    "exact_snippets": "With or without irradiation to the back",
                    "criterion": "irradiation to the back",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": [
                                "with",
                                "without"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "* No obvious other source of pain based on history and physical examination by the attending endosonographer",
            "criterions": [
                {
                    "exact_snippets": "No obvious other source of pain based on history and physical examination",
                    "criterion": "other source of pain",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* No possibility of surgical management",
            "criterions": [
                {
                    "exact_snippets": "No possibility of surgical management",
                    "criterion": "surgical management",
                    "requirements": [
                        {
                            "requirement_type": "possibility",
                            "expected_value": false
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Signed, informed consent",
            "criterions": [
                {
                    "exact_snippets": "Signed, informed consent",
                    "criterion": "informed consent",
                    "requirements": [
                        {
                            "requirement_type": "signed",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* Allergy to bupivicaine",
            "criterions": [
                {
                    "exact_snippets": "Allergy to bupivicaine",
                    "criterion": "allergy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": "bupivicaine"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Age < 18 years",
            "criterions": [
                {
                    "exact_snippets": "Age < 18 years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": {
                                "operator": "<",
                                "value": 18,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Inability or unwillingness to give informed consent",
            "criterions": [
                {
                    "exact_snippets": "Inability ... to give informed consent",
                    "criterion": "ability to give informed consent",
                    "requirements": [
                        {
                            "requirement_type": "ability",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "unwillingness to give informed consent",
                    "criterion": "willingness to give informed consent",
                    "requirements": [
                        {
                            "requirement_type": "willingness",
                            "expected_value": true
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}