{
    "info": {
        "nct_id": "NCT01120262",
        "official_title": "Germline Polymorphisms Associated With the PSA Response in Men With Metastatic Prostate Cancer Treated With Androgen Deprivation Therapy",
        "inclusion_criteria": "Healthy volunteers allowed\nMust be MALE\nMust have minimum age of 18 Years\nMust have maximum age of 120 Years",
        "exclusion_criteria": "",
        "miscellaneous_criteria": "DISEASE CHARACTERISTICS:\n\n* Diagnosed with metastatic prostate cancer\n* Accrued to SWOG-9346 and received androgen-deprivation therapy (ADT)\n* Must have serum PSA values from the beginning to the end of 8 courses of ADT\n* Must have whole blood or serum samples available\n\nPATIENT CHARACTERISTICS:\n\n* Caucasian and African-American participants\n\nPRIOR CONCURRENT THERAPY:\n\n* See Disease Characteristics"
    },
    "inclusion_lines": [
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must be MALE",
            "criterions": [
                {
                    "exact_snippets": "Must be MALE",
                    "criterion": "gender",
                    "requirements": [
                        {
                            "requirement_type": "value",
                            "expected_value": "male"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have maximum age of 120 Years",
            "criterions": [
                {
                    "exact_snippets": "maximum age of 120 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 120,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [],
    "miscellaneous_lines": [
        {
            "line": "DISEASE CHARACTERISTICS:",
            "criterions": [
                {
                    "exact_snippets": "DISEASE CHARACTERISTICS",
                    "criterion": "disease characteristics",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Diagnosed with metastatic prostate cancer",
            "criterions": [
                {
                    "exact_snippets": "Diagnosed with metastatic prostate cancer",
                    "criterion": "metastatic prostate cancer",
                    "requirements": [
                        {
                            "requirement_type": "diagnosis",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Accrued to SWOG-9346 and received androgen-deprivation therapy (ADT)",
            "criterions": [
                {
                    "exact_snippets": "Accrued to SWOG-9346",
                    "criterion": "accrual to SWOG-9346",
                    "requirements": [
                        {
                            "requirement_type": "participation",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "received androgen-deprivation therapy (ADT)",
                    "criterion": "androgen-deprivation therapy (ADT)",
                    "requirements": [
                        {
                            "requirement_type": "treatment received",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Must have serum PSA values from the beginning to the end of 8 courses of ADT",
            "criterions": [
                {
                    "exact_snippets": "Must have serum PSA values",
                    "criterion": "serum PSA values",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "from the beginning to the end of 8 courses of ADT",
                    "criterion": "duration of serum PSA values",
                    "requirements": [
                        {
                            "requirement_type": "duration",
                            "expected_value": "from the beginning to the end of 8 courses of ADT"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Must have whole blood or serum samples available",
            "criterions": [
                {
                    "exact_snippets": "whole blood or serum samples available",
                    "criterion": "whole blood samples",
                    "requirements": [
                        {
                            "requirement_type": "availability",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "whole blood or serum samples available",
                    "criterion": "serum samples",
                    "requirements": [
                        {
                            "requirement_type": "availability",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Caucasian and African-American participants",
            "criterions": [
                {
                    "exact_snippets": "Caucasian",
                    "criterion": "ethnicity",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": "Caucasian"
                        }
                    ]
                },
                {
                    "exact_snippets": "African-American",
                    "criterion": "ethnicity",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": "African-American"
                        }
                    ]
                }
            ]
        },
        {
            "line": "PRIOR CONCURRENT THERAPY:",
            "criterions": [
                {
                    "exact_snippets": "PRIOR CONCURRENT THERAPY",
                    "criterion": "prior concurrent therapy",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* See Disease Characteristics",
            "criterions": [
                {
                    "exact_snippets": "Disease Characteristics",
                    "criterion": "disease characteristics",
                    "requirements": [
                        {
                            "requirement_type": "N/A",
                            "expected_value": "see details"
                        }
                    ]
                }
            ]
        }
    ],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": [
        {
            "line": "PATIENT CHARACTERISTICS:",
            "criterions": []
        }
    ]
}