{
    "info": {
        "nct_id": "NCT01102231",
        "official_title": "Phase II Study of Pemetrexed + Cetuximab + Cisplatin With Concurrent Chemoradiotherapy in Stage III Non-small Cell Lung Cancer (NSCLC)",
        "inclusion_criteria": "* non-squamous stage III non-small cell lung cancer\n* measurable disease (RECIST 1.1)\n* ECOG performance status 0-1\n* normal organ and marrow function\nHealthy volunteers allowed\nMust have minimum age of 18 Years\nMust have maximum age of 70 Years",
        "exclusion_criteria": "* prior chest radiation therapy\n* history of any cancer other than NSCLC (except non-melanoma skin cancer or carcinoma in situ of the cervix) within the last five years.\n* Prior therapy with known specific inhibitors of the EGFR.\n* history of severe allergic reaction to prior therapy with monoclonal antibodies",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "line": "* non-squamous stage III non-small cell lung cancer",
            "criterions": [
                {
                    "exact_snippets": "non-squamous",
                    "criterion": "cancer type",
                    "requirements": [
                        {
                            "requirement_type": "specificity",
                            "expected_value": "non-squamous"
                        }
                    ]
                },
                {
                    "exact_snippets": "stage III",
                    "criterion": "cancer stage",
                    "requirements": [
                        {
                            "requirement_type": "stage",
                            "expected_value": "III"
                        }
                    ]
                },
                {
                    "exact_snippets": "non-small cell lung cancer",
                    "criterion": "cancer type",
                    "requirements": [
                        {
                            "requirement_type": "specificity",
                            "expected_value": "non-small cell lung cancer"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* measurable disease (RECIST 1.1)",
            "criterions": [
                {
                    "exact_snippets": "measurable disease (RECIST 1.1)",
                    "criterion": "measurable disease",
                    "requirements": [
                        {
                            "requirement_type": "criteria",
                            "expected_value": "RECIST 1.1"
                        }
                    ]
                }
            ]
        },
        {
            "line": "* ECOG performance status 0-1",
            "criterions": [
                {
                    "exact_snippets": "ECOG performance status 0-1",
                    "criterion": "ECOG performance status",
                    "requirements": [
                        {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 0,
                                        "unit": "N/A"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 1,
                                        "unit": "N/A"
                                    }
                                ]
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "* normal organ and marrow function",
            "criterions": [
                {
                    "exact_snippets": "normal organ",
                    "criterion": "organ function",
                    "requirements": [
                        {
                            "requirement_type": "functionality",
                            "expected_value": "normal"
                        }
                    ]
                },
                {
                    "exact_snippets": "normal ... marrow function",
                    "criterion": "marrow function",
                    "requirements": [
                        {
                            "requirement_type": "functionality",
                            "expected_value": "normal"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 18 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 18 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 18,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have maximum age of 70 Years",
            "criterions": [
                {
                    "exact_snippets": "maximum age of 70 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 70,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [
        {
            "line": "* prior chest radiation therapy",
            "criterions": [
                {
                    "exact_snippets": "prior chest radiation therapy",
                    "criterion": "chest radiation therapy",
                    "requirements": [
                        {
                            "requirement_type": "prior",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* history of any cancer other than NSCLC (except non-melanoma skin cancer or carcinoma in situ of the cervix) within the last five years.",
            "criterions": [
                {
                    "exact_snippets": "history of any cancer other than NSCLC",
                    "criterion": "history of cancer",
                    "requirements": [
                        {
                            "requirement_type": "type",
                            "expected_value": "any cancer other than NSCLC"
                        },
                        {
                            "requirement_type": "time frame",
                            "expected_value": "within the last five years"
                        }
                    ]
                },
                {
                    "exact_snippets": "except non-melanoma skin cancer or carcinoma in situ of the cervix",
                    "criterion": "cancer type exception",
                    "requirements": [
                        {
                            "requirement_type": "type",
                            "expected_value": [
                                "non-melanoma skin cancer",
                                "carcinoma in situ of the cervix"
                            ]
                        }
                    ]
                }
            ]
        },
        {
            "line": "* Prior therapy with known specific inhibitors of the EGFR.",
            "criterions": [
                {
                    "exact_snippets": "Prior therapy with known specific inhibitors of the EGFR",
                    "criterion": "prior therapy with EGFR inhibitors",
                    "requirements": [
                        {
                            "requirement_type": "presence",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "* history of severe allergic reaction to prior therapy with monoclonal antibodies",
            "criterions": [
                {
                    "exact_snippets": "history of severe allergic reaction to prior therapy with monoclonal antibodies",
                    "criterion": "severe allergic reaction to monoclonal antibodies",
                    "requirements": [
                        {
                            "requirement_type": "history",
                            "expected_value": true
                        }
                    ]
                }
            ]
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}