{
    "info": {
        "nct_id": "NCT00340457",
        "official_title": "Case-Control Study of Renal Cell Cancer Among Caucasians and African Americans in the United States",
        "inclusion_criteria": "Healthy volunteers allowed\nMust have minimum age of 20 Years\nMust have maximum age of 79 Years",
        "exclusion_criteria": "",
        "miscellaneous_criteria": "* INCLUSION CRITERIA - CASES:\n\nResidents of the study areas who are diagnosed with histologically confirmed renal cell carcinoma at ages 20 to 79 years over a four year study will be potentially eligible for the study.\n\nIn addition, only eligible patients who are mentally/physically able to provide informed consent and undergo interviews will be approached for participation.\n\nINCLUSION CRITERIA - CONTROLS:\n\nPopulation-based controls will be frequency-matched to the cases by study center, race, age and sex, at the ratio of one control per case for non-African Americans and two controls per case for African Americans.\n\nControls aged 65 years and older will be identified from Health Care Financing Administration (HCFA) files.\n\nControls under age 65 years will be identified from residents of the study areas by random telephone digit dialing (RDD)."
    },
    "inclusion_lines": [
        {
            "line": "Healthy volunteers allowed",
            "criterions": [
                {
                    "exact_snippets": "Healthy volunteers allowed",
                    "criterion": "volunteer health status",
                    "requirements": [
                        {
                            "requirement_type": "status",
                            "expected_value": "healthy"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have minimum age of 20 Years",
            "criterions": [
                {
                    "exact_snippets": "minimum age of 20 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum",
                            "expected_value": {
                                "operator": ">=",
                                "value": 20,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Must have maximum age of 79 Years",
            "criterions": [
                {
                    "exact_snippets": "maximum age of 79 Years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "maximum",
                            "expected_value": {
                                "operator": "<=",
                                "value": 79,
                                "unit": "Years"
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "exclusion_lines": [],
    "miscellaneous_lines": [
        {
            "line": "Residents of the study areas who are diagnosed with histologically confirmed renal cell carcinoma at ages 20 to 79 years over a four year study will be potentially eligible for the study.",
            "criterions": [
                {
                    "exact_snippets": "Residents of the study areas",
                    "criterion": "residency",
                    "requirements": [
                        {
                            "requirement_type": "location",
                            "expected_value": "study areas"
                        }
                    ]
                },
                {
                    "exact_snippets": "diagnosed with histologically confirmed renal cell carcinoma",
                    "criterion": "renal cell carcinoma diagnosis",
                    "requirements": [
                        {
                            "requirement_type": "confirmation method",
                            "expected_value": "histologically confirmed"
                        }
                    ]
                },
                {
                    "exact_snippets": "at ages 20 to 79 years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": ">=",
                                        "value": 20,
                                        "unit": "years"
                                    },
                                    {
                                        "operator": "<=",
                                        "value": 79,
                                        "unit": "years"
                                    }
                                ]
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "In addition, only eligible patients who are mentally/physically able to provide informed consent and undergo interviews will be approached for participation.",
            "criterions": [
                {
                    "exact_snippets": "mentally/physically able to provide informed consent",
                    "criterion": "ability to provide informed consent",
                    "requirements": [
                        {
                            "requirement_type": "capability",
                            "expected_value": true
                        }
                    ]
                },
                {
                    "exact_snippets": "mentally/physically able to ... undergo interviews",
                    "criterion": "ability to undergo interviews",
                    "requirements": [
                        {
                            "requirement_type": "capability",
                            "expected_value": true
                        }
                    ]
                }
            ]
        },
        {
            "line": "Population-based controls will be frequency-matched to the cases by study center, race, age and sex, at the ratio of one control per case for non-African Americans and two controls per case for African Americans.",
            "criterions": [
                {
                    "exact_snippets": "study center",
                    "criterion": "study center",
                    "requirements": [
                        {
                            "requirement_type": "matching",
                            "expected_value": "frequency-matched to the cases"
                        }
                    ]
                },
                {
                    "exact_snippets": "race",
                    "criterion": "race",
                    "requirements": [
                        {
                            "requirement_type": "matching",
                            "expected_value": "frequency-matched to the cases"
                        }
                    ]
                },
                {
                    "exact_snippets": "age",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "matching",
                            "expected_value": "frequency-matched to the cases"
                        }
                    ]
                },
                {
                    "exact_snippets": "sex",
                    "criterion": "sex",
                    "requirements": [
                        {
                            "requirement_type": "matching",
                            "expected_value": "frequency-matched to the cases"
                        }
                    ]
                }
            ]
        },
        {
            "line": "Controls aged 65 years and older will be identified from Health Care Financing Administration (HCFA) files.",
            "criterions": [
                {
                    "exact_snippets": "aged 65 years and older",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "minimum age",
                            "expected_value": {
                                "operator": ">=",
                                "value": 65,
                                "unit": "years"
                            }
                        }
                    ]
                }
            ]
        },
        {
            "line": "Controls under age 65 years will be identified from residents of the study areas by random telephone digit dialing (RDD).",
            "criterions": [
                {
                    "exact_snippets": "under age 65 years",
                    "criterion": "age",
                    "requirements": [
                        {
                            "requirement_type": "range",
                            "expected_value": {
                                "comparisons": [
                                    {
                                        "operator": "<",
                                        "value": 65,
                                        "unit": "years"
                                    }
                                ]
                            }
                        }
                    ]
                }
            ]
        }
    ],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": [
        {
            "line": "* INCLUSION CRITERIA - CASES:",
            "criterions": []
        },
        {
            "line": "INCLUSION CRITERIA - CONTROLS:",
            "criterions": []
        }
    ]
}