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a b/output/matching/aggregated_truth.json
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{
2
    "criteria": {
3
        "volunteer health status": {
4
            "criterion": "volunteer health status",
5
            "requirements": {
6
                "status": {
7
                    "requirement_type": "status",
8
                    "groups": {
9
                        "healthy": {
10
                            "expected_value": "healthy",
11
                            "trial_ids": [
12
                                "NCT00001073",
13
                                "NCT00001120",
14
                                "NCT00001148",
15
                                "NCT00001272",
16
                                "NCT00001582",
17
                                "NCT00001748",
18
                                "NCT00002262",
19
                                "NCT00002476",
20
                                "NCT00002620",
21
                                "NCT00002631"
22
                            ],
23
                            "truth_value": "false"
24
                        }
25
                    }
26
                }
27
            }
28
        },
29
        "gender": {
30
            "criterion": "gender",
31
            "requirements": {
32
                "expected gender": {
33
                    "requirement_type": "expected gender",
34
                    "groups": {
35
                        "female": {
36
                            "expected_value": "female",
37
                            "trial_ids": [
38
                                "NCT00001073"
39
                            ],
40
                            "truth_value": "false"
41
                        }
42
                    }
43
                },
44
                "gender": {
45
                    "requirement_type": "gender",
46
                    "groups": {
47
                        "female": {
48
                            "expected_value": "female",
49
                            "trial_ids": [
50
                                "NCT00001073"
51
                            ],
52
                            "truth_value": "false"
53
                        }
54
                    }
55
                },
56
                "presence": {
57
                    "requirement_type": "presence",
58
                    "groups": {
59
                        "['male', 'female']": {
60
                            "expected_value": [
61
                                "male",
62
                                "female"
63
                            ],
64
                            "trial_ids": [
65
                                "NCT00001148"
66
                            ],
67
                            "truth_value": "true"
68
                        }
69
                    }
70
                },
71
                "expected_value": {
72
                    "requirement_type": "expected_value",
73
                    "groups": {
74
                        "female": {
75
                            "expected_value": "female",
76
                            "trial_ids": [
77
                                "NCT00001272"
78
                            ],
79
                            "truth_value": "false"
80
                        },
81
                        "male": {
82
                            "expected_value": "male",
83
                            "trial_ids": [
84
                                "NCT00002262"
85
                            ],
86
                            "truth_value": "true"
87
                        }
88
                    }
89
                }
90
            }
91
        },
92
        "age": {
93
            "criterion": "age",
94
            "requirements": {
95
                "minimum": {
96
                    "requirement_type": "minimum",
97
                    "groups": {
98
                        "operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=13 unit='Years'": {
99
                            "expected_value": {
100
                                "operator": ">=",
101
                                "value": 13,
102
                                "unit": "Years"
103
                            },
104
                            "trial_ids": [
105
                                "NCT00001073"
106
                            ],
107
                            "truth_value": "true"
108
                        },
109
                        "operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=18 unit='Years'": {
110
                            "expected_value": {
111
                                "operator": ">=",
112
                                "value": 18,
113
                                "unit": "Years"
114
                            },
115
                            "trial_ids": [
116
                                "NCT00001120",
117
                                "NCT00001582",
118
                                "NCT00002262",
119
                                "NCT00002476",
120
                                "NCT00002631"
121
                            ],
122
                            "truth_value": "false"
123
                        },
124
                        "operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=16 unit='Years'": {
125
                            "expected_value": {
126
                                "operator": ">=",
127
                                "value": 16,
128
                                "unit": "Years"
129
                            },
130
                            "trial_ids": [
131
                                "NCT00002620"
132
                            ],
133
                            "truth_value": "false"
134
                        }
135
                    }
136
                },
137
                "minimum age": {
138
                    "requirement_type": "minimum age",
139
                    "groups": {
140
                        "operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=13 unit='years'": {
141
                            "expected_value": {
142
                                "operator": ">=",
143
                                "value": 13,
144
                                "unit": "years"
145
                            },
146
                            "trial_ids": [
147
                                "NCT00001073"
148
                            ],
149
                            "truth_value": "true"
150
                        },
151
                        "operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=18 unit='years'": {
152
                            "expected_value": {
153
                                "operator": ">=",
154
                                "value": 18,
155
                                "unit": "years"
156
                            },
157
                            "trial_ids": [
158
                                "NCT00001120"
159
                            ],
160
                            "truth_value": "false"
161
                        },
162
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=18 unit='years'": {
163
                            "expected_value": {
164
                                "operator": ">",
165
                                "value": 18,
166
                                "unit": "years"
167
                            },
168
                            "trial_ids": [
169
                                "NCT00001748"
170
                            ],
171
                            "truth_value": "false"
172
                        },
173
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=16 unit='years'": {
174
                            "expected_value": {
175
                                "operator": ">",
176
                                "value": 16,
177
                                "unit": "years"
178
                            },
179
                            "trial_ids": [
180
                                "NCT00002620"
181
                            ],
182
                            "truth_value": "false"
183
                        }
184
                    }
185
                },
186
                "range": {
187
                    "requirement_type": "range",
188
                    "groups": {
189
                        "comparisons=[LLMNumericalComparison(operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='>, value=18, unit='years'), LLMNumericalComparison(operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='>, value=75, unit='years')]": {
190
                            "expected_value": {
191
                                "comparisons": [
192
                                    {
193
                                        "operator": ">=",
194
                                        "value": 18,
195
                                        "unit": "years"
196
                                    },
197
                                    {
198
                                        "operator": "<=",
199
                                        "value": 75,
200
                                        "unit": "years"
201
                                    }
202
                                ]
203
                            },
204
                            "trial_ids": [
205
                                "NCT00001148"
206
                            ],
207
                            "truth_value": "false"
208
                        },
209
                        "comparisons=[LLMNumericalComparison(operator=<LLMOperator.LESS_THAN: '<'>, value=18, unit='years')]": {
210
                            "expected_value": {
211
                                "comparisons": [
212
                                    {
213
                                        "operator": "<",
214
                                        "value": 18,
215
                                        "unit": "years"
216
                                    }
217
                                ]
218
                            },
219
                            "trial_ids": [
220
                                "NCT00001582"
221
                            ],
222
                            "truth_value": "true"
223
                        },
224
                        "comparisons=[LLMNumericalComparison(operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='>, value=10, unit='years'), LLMNumericalComparison(operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='>, value=45, unit='years')]": {
225
                            "expected_value": {
226
                                "comparisons": [
227
                                    {
228
                                        "operator": ">=",
229
                                        "value": 10,
230
                                        "unit": "years"
231
                                    },
232
                                    {
233
                                        "operator": "<=",
234
                                        "value": 45,
235
                                        "unit": "years"
236
                                    }
237
                                ]
238
                            },
239
                            "trial_ids": [
240
                                "NCT00001748"
241
                            ],
242
                            "truth_value": "true"
243
                        }
244
                    }
245
                },
246
                "value": {
247
                    "requirement_type": "value",
248
                    "groups": {
249
                        "operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=18 unit='years'": {
250
                            "expected_value": {
251
                                "operator": ">=",
252
                                "value": 18,
253
                                "unit": "years"
254
                            },
255
                            "trial_ids": [
256
                                "NCT00001582"
257
                            ],
258
                            "truth_value": "false"
259
                        }
260
                    }
261
                },
262
                "maximum": {
263
                    "requirement_type": "maximum",
264
                    "groups": {
265
                        "operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=70 unit='Years'": {
266
                            "expected_value": {
267
                                "operator": "<=",
268
                                "value": 70,
269
                                "unit": "Years"
270
                            },
271
                            "trial_ids": [
272
                                "NCT00002262"
273
                            ],
274
                            "truth_value": "true"
275
                        }
276
                    }
277
                },
278
                "maximum age": {
279
                    "requirement_type": "maximum age",
280
                    "groups": {
281
                        "operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=75 unit='years'": {
282
                            "expected_value": {
283
                                "operator": "<=",
284
                                "value": 75,
285
                                "unit": "years"
286
                            },
287
                            "trial_ids": [
288
                                "NCT00002476"
289
                            ],
290
                            "truth_value": "true"
291
                        }
292
                    }
293
                }
294
            }
295
        },
296
        "hiv status": {
297
            "criterion": "hiv status",
298
            "requirements": {
299
                "status": {
300
                    "requirement_type": "status",
301
                    "groups": {
302
                        "positive": {
303
                            "expected_value": "positive",
304
                            "trial_ids": [
305
                                "NCT00001073",
306
                                "NCT00001120",
307
                                "NCT00001148"
308
                            ],
309
                            "truth_value": "unknown"
310
                        },
311
                        "negative": {
312
                            "expected_value": "negative",
313
                            "trial_ids": [
314
                                "NCT00001748"
315
                            ],
316
                            "truth_value": "unknown"
317
                        }
318
                    }
319
                }
320
            }
321
        },
322
        "parental consent": {
323
            "criterion": "parental consent",
324
            "requirements": {
325
                "requirement": {
326
                    "requirement_type": "requirement",
327
                    "groups": {
328
                        "required if under 18": {
329
                            "expected_value": "required if under 18",
330
                            "trial_ids": [
331
                                "NCT00001073"
332
                            ],
333
                            "truth_value": "unknown"
334
                        }
335
                    }
336
                }
337
            }
338
        },
339
        "cervical tumors": {
340
            "criterion": "cervical tumors",
341
            "requirements": {
342
                "presence": {
343
                    "requirement_type": "presence",
344
                    "groups": {
345
                        "True": {
346
                            "expected_value": true,
347
                            "trial_ids": [
348
                                "NCT00001073"
349
                            ],
350
                            "truth_value": "unknown"
351
                        }
352
                    }
353
                },
354
                "determination method": {
355
                    "requirement_type": "determination method",
356
                    "groups": {
357
                        "biopsy": {
358
                            "expected_value": "biopsy",
359
                            "trial_ids": [
360
                                "NCT00001073"
361
                            ],
362
                            "truth_value": "unknown"
363
                        }
364
                    }
365
                }
366
            }
367
        },
368
        "contraceptive use": {
369
            "criterion": "contraceptive use",
370
            "requirements": {
371
                "methods": {
372
                    "requirement_type": "methods",
373
                    "groups": {
374
                        "['condoms', 'the pill']": {
375
                            "expected_value": [
376
                                "condoms",
377
                                "the pill"
378
                            ],
379
                            "trial_ids": [
380
                                "NCT00001073"
381
                            ],
382
                            "truth_value": "unknown"
383
                        }
384
                    }
385
                }
386
            }
387
        },
388
        "cancer therapies": {
389
            "criterion": "cancer therapies",
390
            "requirements": {
391
                "recency": {
392
                    "requirement_type": "recency",
393
                    "groups": {
394
                        "comparisons=[LLMNumericalComparison(operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='>, value=4, unit='months')]": {
395
                            "expected_value": {
396
                                "comparisons": [
397
                                    {
398
                                        "operator": "<=",
399
                                        "value": 4,
400
                                        "unit": "months"
401
                                    }
402
                                ]
403
                            },
404
                            "trial_ids": [
405
                                "NCT00001073"
406
                            ],
407
                            "truth_value": "unknown"
408
                        }
409
                    }
410
                }
411
            }
412
        },
413
        "hysterectomy": {
414
            "criterion": "hysterectomy",
415
            "requirements": {
416
                "time since procedure": {
417
                    "requirement_type": "time since procedure",
418
                    "groups": {
419
                        "operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=4 unit='months'": {
420
                            "expected_value": {
421
                                "operator": "<=",
422
                                "value": 4,
423
                                "unit": "months"
424
                            },
425
                            "trial_ids": [
426
                                "NCT00001073"
427
                            ],
428
                            "truth_value": "unknown"
429
                        }
430
                    }
431
                }
432
            }
433
        },
434
        "tetracycline usage": {
435
            "criterion": "tetracycline usage",
436
            "requirements": {
437
                "presence": {
438
                    "requirement_type": "presence",
439
                    "groups": {
440
                        "True": {
441
                            "expected_value": true,
442
                            "trial_ids": [
443
                                "NCT00001073"
444
                            ],
445
                            "truth_value": "unknown"
446
                        }
447
                    }
448
                }
449
            }
450
        },
451
        "vitamin a usage": {
452
            "criterion": "vitamin a usage",
453
            "requirements": {
454
                "presence": {
455
                    "requirement_type": "presence",
456
                    "groups": {
457
                        "True": {
458
                            "expected_value": true,
459
                            "trial_ids": [
460
                                "NCT00001073"
461
                            ],
462
                            "truth_value": "unknown"
463
                        }
464
                    }
465
                }
466
            }
467
        },
468
        "medication history": {
469
            "criterion": "medication history",
470
            "requirements": {
471
                "presence": {
472
                    "requirement_type": "presence",
473
                    "groups": {
474
                        "True": {
475
                            "expected_value": true,
476
                            "trial_ids": [
477
                                "NCT00001073"
478
                            ],
479
                            "truth_value": "unknown"
480
                        }
481
                    }
482
                }
483
            }
484
        },
485
        "anti-hiv drugs and medications to prevent aids-related opportunistic infections": {
486
            "criterion": "anti-hiv drugs and medications to prevent aids-related opportunistic infections",
487
            "requirements": {
488
                "approval": {
489
                    "requirement_type": "approval",
490
                    "groups": {
491
                        "True": {
492
                            "expected_value": true,
493
                            "trial_ids": [
494
                                "NCT00001073"
495
                            ],
496
                            "truth_value": "unknown"
497
                        }
498
                    }
499
                }
500
            }
501
        },
502
        "pregnancy": {
503
            "criterion": "pregnancy",
504
            "requirements": {
505
                "presence": {
506
                    "requirement_type": "presence",
507
                    "groups": {
508
                        "True": {
509
                            "expected_value": true,
510
                            "trial_ids": [
511
                                "NCT00001073"
512
                            ],
513
                            "truth_value": "unknown"
514
                        },
515
                        "False": {
516
                            "expected_value": false,
517
                            "trial_ids": [
518
                                "NCT00001582"
519
                            ],
520
                            "truth_value": "unknown"
521
                        }
522
                    }
523
                }
524
            }
525
        },
526
        "cd4+ cell count": {
527
            "criterion": "cd4+ cell count",
528
            "requirements": {
529
                "quantity": {
530
                    "requirement_type": "quantity",
531
                    "groups": {
532
                        "operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=200 unit='cells/mm3'": {
533
                            "expected_value": {
534
                                "operator": "<=",
535
                                "value": 200,
536
                                "unit": "cells/mm3"
537
                            },
538
                            "trial_ids": [
539
                                "NCT00001120"
540
                            ],
541
                            "truth_value": "unknown"
542
                        }
543
                    }
544
                }
545
            }
546
        },
547
        "follow-up availability": {
548
            "criterion": "follow-up availability",
549
            "requirements": {
550
                "duration": {
551
                    "requirement_type": "duration",
552
                    "groups": {
553
                        "operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=3 unit='years'": {
554
                            "expected_value": {
555
                                "operator": ">=",
556
                                "value": 3,
557
                                "unit": "years"
558
                            },
559
                            "trial_ids": [
560
                                "NCT00001120"
561
                            ],
562
                            "truth_value": "unknown"
563
                        }
564
                    }
565
                }
566
            }
567
        },
568
        "glioblastoma multiforme": {
569
            "criterion": "glioblastoma multiforme",
570
            "requirements": {
571
                "diagnosis": {
572
                    "requirement_type": "diagnosis",
573
                    "groups": {
574
                        "True": {
575
                            "expected_value": true,
576
                            "trial_ids": [
577
                                "NCT00001148"
578
                            ],
579
                            "truth_value": "unknown"
580
                        }
581
                    }
582
                },
583
                "confirmation method": {
584
                    "requirement_type": "confirmation method",
585
                    "groups": {
586
                        "biopsy-proven": {
587
                            "expected_value": "biopsy-proven",
588
                            "trial_ids": [
589
                                "NCT00001148"
590
                            ],
591
                            "truth_value": "unknown"
592
                        }
593
                    }
594
                }
595
            }
596
        },
597
        "anaplastic astrocytoma": {
598
            "criterion": "anaplastic astrocytoma",
599
            "requirements": {
600
                "diagnosis": {
601
                    "requirement_type": "diagnosis",
602
                    "groups": {
603
                        "True": {
604
                            "expected_value": true,
605
                            "trial_ids": [
606
                                "NCT00001148"
607
                            ],
608
                            "truth_value": "unknown"
609
                        }
610
                    }
611
                },
612
                "confirmation method": {
613
                    "requirement_type": "confirmation method",
614
                    "groups": {
615
                        "biopsy-proven": {
616
                            "expected_value": "biopsy-proven",
617
                            "trial_ids": [
618
                                "NCT00001148"
619
                            ],
620
                            "truth_value": "unknown"
621
                        }
622
                    }
623
                },
624
                "confirmation": {
625
                    "requirement_type": "confirmation",
626
                    "groups": {
627
                        "histologically confirmed": {
628
                            "expected_value": "histologically confirmed",
629
                            "trial_ids": [
630
                                "NCT00002620"
631
                            ],
632
                            "truth_value": "unknown"
633
                        }
634
                    }
635
                }
636
            }
637
        },
638
        "who grade": {
639
            "criterion": "who grade",
640
            "requirements": {
641
                "classification": {
642
                    "requirement_type": "classification",
643
                    "groups": {
644
                        "['III', 'IV']": {
645
                            "expected_value": [
646
                                "III",
647
                                "IV"
648
                            ],
649
                            "trial_ids": [
650
                                "NCT00001148"
651
                            ],
652
                            "truth_value": "unknown"
653
                        }
654
                    }
655
                }
656
            }
657
        },
658
        "informed consent": {
659
            "criterion": "informed consent",
660
            "requirements": {
661
                "presence": {
662
                    "requirement_type": "presence",
663
                    "groups": {
664
                        "True": {
665
                            "expected_value": true,
666
                            "trial_ids": [
667
                                "NCT00001148",
668
                                "NCT00001748"
669
                            ],
670
                            "truth_value": "unknown"
671
                        }
672
                    }
673
                },
674
                "ability": {
675
                    "requirement_type": "ability",
676
                    "groups": {
677
                        "True": {
678
                            "expected_value": true,
679
                            "trial_ids": [
680
                                "NCT00001272"
681
                            ],
682
                            "truth_value": "unknown"
683
                        }
684
                    }
685
                },
686
                "given": {
687
                    "requirement_type": "given",
688
                    "groups": {
689
                        "True": {
690
                            "expected_value": true,
691
                            "trial_ids": [
692
                                "NCT00001748"
693
                            ],
694
                            "truth_value": "unknown"
695
                        }
696
                    }
697
                }
698
            }
699
        },
700
        "karnofsky performance scale score": {
701
            "criterion": "karnofsky performance scale score",
702
            "requirements": {
703
                "value": {
704
                    "requirement_type": "value",
705
                    "groups": {
706
                        "operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=60 unit='N/A'": {
707
                            "expected_value": {
708
                                "operator": ">=",
709
                                "value": 60,
710
                                "unit": "N/A"
711
                            },
712
                            "trial_ids": [
713
                                "NCT00001148"
714
                            ],
715
                            "truth_value": "unknown"
716
                        },
717
                        "operator=<LLMOperator.LESS_THAN: '<'> value=60 unit='N/A'": {
718
                            "expected_value": {
719
                                "operator": "<",
720
                                "value": 60,
721
                                "unit": "N/A"
722
                            },
723
                            "trial_ids": [
724
                                "NCT00001148"
725
                            ],
726
                            "truth_value": "unknown"
727
                        }
728
                    }
729
                }
730
            }
731
        },
732
        "race": {
733
            "criterion": "race",
734
            "requirements": {
735
                "eligibility": {
736
                    "requirement_type": "eligibility",
737
                    "groups": {
738
                        "True": {
739
                            "expected_value": true,
740
                            "trial_ids": [
741
                                "NCT00001148"
742
                            ],
743
                            "truth_value": "unknown"
744
                        }
745
                    }
746
                }
747
            }
748
        },
749
        "sex": {
750
            "criterion": "sex",
751
            "requirements": {
752
                "eligibility": {
753
                    "requirement_type": "eligibility",
754
                    "groups": {
755
                        "True": {
756
                            "expected_value": true,
757
                            "trial_ids": [
758
                                "NCT00001148"
759
                            ],
760
                            "truth_value": "unknown"
761
                        }
762
                    }
763
                }
764
            }
765
        },
766
        "age group": {
767
            "criterion": "age group",
768
            "requirements": {
769
                "eligibility": {
770
                    "requirement_type": "eligibility",
771
                    "groups": {
772
                        "False": {
773
                            "expected_value": false,
774
                            "trial_ids": [
775
                                "NCT00001148"
776
                            ],
777
                            "truth_value": "unknown"
778
                        }
779
                    }
780
                }
781
            }
782
        },
783
        "acceptance for glioma resection": {
784
            "criterion": "acceptance for glioma resection",
785
            "requirements": {
786
                "protocol": {
787
                    "requirement_type": "protocol",
788
                    "groups": {
789
                        "existing NINDS protocols": {
790
                            "expected_value": "existing NINDS protocols",
791
                            "trial_ids": [
792
                                "NCT00001148"
793
                            ],
794
                            "truth_value": "unknown"
795
                        }
796
                    }
797
                }
798
            }
799
        },
800
        "tumor tissue": {
801
            "criterion": "tumor tissue",
802
            "requirements": {
803
                "availability": {
804
                    "requirement_type": "availability",
805
                    "groups": {
806
                        "True": {
807
                            "expected_value": true,
808
                            "trial_ids": [
809
                                "NCT00001148"
810
                            ],
811
                            "truth_value": "unknown"
812
                        }
813
                    }
814
                }
815
            }
816
        },
817
        "tumor-specific mutation(s)": {
818
            "criterion": "tumor-specific mutation(s)",
819
            "requirements": {
820
                "identification": {
821
                    "requirement_type": "identification",
822
                    "groups": {
823
                        "True": {
824
                            "expected_value": true,
825
                            "trial_ids": [
826
                                "NCT00001148"
827
                            ],
828
                            "truth_value": "unknown"
829
                        }
830
                    }
831
                }
832
            }
833
        },
834
        "clinical stability": {
835
            "criterion": "clinical stability",
836
            "requirements": {
837
                "stability": {
838
                    "requirement_type": "stability",
839
                    "groups": {
840
                        "False": {
841
                            "expected_value": false,
842
                            "trial_ids": [
843
                                "NCT00001148"
844
                            ],
845
                            "truth_value": "unknown"
846
                        }
847
                    }
848
                }
849
            }
850
        },
851
        "total bilirubin": {
852
            "criterion": "total bilirubin",
853
            "requirements": {
854
                "level": {
855
                    "requirement_type": "level",
856
                    "groups": {
857
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=2.0 unit='mg/dl'": {
858
                            "expected_value": {
859
                                "operator": ">",
860
                                "value": 2.0,
861
                                "unit": "mg/dl"
862
                            },
863
                            "trial_ids": [
864
                                "NCT00001148"
865
                            ],
866
                            "truth_value": "unknown"
867
                        }
868
                    }
869
                }
870
            }
871
        },
872
        "ast or alt": {
873
            "criterion": "ast or alt",
874
            "requirements": {
875
                "level": {
876
                    "requirement_type": "level",
877
                    "groups": {
878
                        "greater than 3 times the upper limit of normal": {
879
                            "expected_value": "greater than 3 times the upper limit of normal",
880
                            "trial_ids": [
881
                                "NCT00001148"
882
                            ],
883
                            "truth_value": "unknown"
884
                        }
885
                    }
886
                }
887
            }
888
        },
889
        "prothrombin time (pt)": {
890
            "criterion": "prothrombin time (pt)",
891
            "requirements": {
892
                "comparison": {
893
                    "requirement_type": "comparison",
894
                    "groups": {
895
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=1.5 unit='times control'": {
896
                            "expected_value": {
897
                                "operator": ">",
898
                                "value": 1.5,
899
                                "unit": "times control"
900
                            },
901
                            "trial_ids": [
902
                                "NCT00001148"
903
                            ],
904
                            "truth_value": "unknown"
905
                        }
906
                    }
907
                }
908
            }
909
        },
910
        "activated partial thromboplastin time (aptt)": {
911
            "criterion": "activated partial thromboplastin time (aptt)",
912
            "requirements": {
913
                "comparison": {
914
                    "requirement_type": "comparison",
915
                    "groups": {
916
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=1.5 unit='times control'": {
917
                            "expected_value": {
918
                                "operator": ">",
919
                                "value": 1.5,
920
                                "unit": "times control"
921
                            },
922
                            "trial_ids": [
923
                                "NCT00001148"
924
                            ],
925
                            "truth_value": "unknown"
926
                        }
927
                    }
928
                }
929
            }
930
        },
931
        "platelet count": {
932
            "criterion": "platelet count",
933
            "requirements": {
934
                "quantity": {
935
                    "requirement_type": "quantity",
936
                    "groups": {
937
                        "operator=<LLMOperator.LESS_THAN: '<'> value=100000 unit='mm3'": {
938
                            "expected_value": {
939
                                "operator": "<",
940
                                "value": 100000,
941
                                "unit": "mm3"
942
                            },
943
                            "trial_ids": [
944
                                "NCT00001148"
945
                            ],
946
                            "truth_value": "unknown"
947
                        },
948
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=100000 unit='N/A'": {
949
                            "expected_value": {
950
                                "operator": ">",
951
                                "value": 100000,
952
                                "unit": "N/A"
953
                            },
954
                            "trial_ids": [
955
                                "NCT00001272"
956
                            ],
957
                            "truth_value": "unknown"
958
                        }
959
                    }
960
                },
961
                "level": {
962
                    "requirement_type": "level",
963
                    "groups": {
964
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=50000 unit='N/A'": {
965
                            "expected_value": {
966
                                "operator": ">",
967
                                "value": 50000,
968
                                "unit": "N/A"
969
                            },
970
                            "trial_ids": [
971
                                "NCT00001582"
972
                            ],
973
                            "truth_value": "unknown"
974
                        }
975
                    }
976
                },
977
                "minimum count": {
978
                    "requirement_type": "minimum count",
979
                    "groups": {
980
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=100000 unit='N/A'": {
981
                            "expected_value": {
982
                                "operator": ">",
983
                                "value": 100000,
984
                                "unit": "N/A"
985
                            },
986
                            "trial_ids": [
987
                                "NCT00002620"
988
                            ],
989
                            "truth_value": "unknown"
990
                        }
991
                    }
992
                }
993
            }
994
        },
995
        "absolute neutrophil count": {
996
            "criterion": "absolute neutrophil count",
997
            "requirements": {
998
                "quantity": {
999
                    "requirement_type": "quantity",
1000
                    "groups": {
1001
                        "operator=<LLMOperator.LESS_THAN: '<'> value=1000 unit='mm3'": {
1002
                            "expected_value": {
1003
                                "operator": "<",
1004
                                "value": 1000,
1005
                                "unit": "mm3"
1006
                            },
1007
                            "trial_ids": [
1008
                                "NCT00001148"
1009
                            ],
1010
                            "truth_value": "unknown"
1011
                        }
1012
                    }
1013
                }
1014
            }
1015
        },
1016
        "acute infection": {
1017
            "criterion": "acute infection",
1018
            "requirements": {
1019
                "presence": {
1020
                    "requirement_type": "presence",
1021
                    "groups": {
1022
                        "True": {
1023
                            "expected_value": true,
1024
                            "trial_ids": [
1025
                                "NCT00001148"
1026
                            ],
1027
                            "truth_value": "unknown"
1028
                        }
1029
                    }
1030
                }
1031
            }
1032
        },
1033
        "acute medical problems": {
1034
            "criterion": "acute medical problems",
1035
            "requirements": {
1036
                "presence": {
1037
                    "requirement_type": "presence",
1038
                    "groups": {
1039
                        "False": {
1040
                            "expected_value": false,
1041
                            "trial_ids": [
1042
                                "NCT00001148"
1043
                            ],
1044
                            "truth_value": "unknown"
1045
                        }
1046
                    }
1047
                }
1048
            }
1049
        },
1050
        "allergy": {
1051
            "criterion": "allergy",
1052
            "requirements": {
1053
                "substance": {
1054
                    "requirement_type": "substance",
1055
                    "groups": {
1056
                        "CT contrast agents": {
1057
                            "expected_value": "CT contrast agents",
1058
                            "trial_ids": [
1059
                                "NCT00001148"
1060
                            ],
1061
                            "truth_value": "unknown"
1062
                        }
1063
                    }
1064
                }
1065
            }
1066
        },
1067
        "tumor-specific gene mutation": {
1068
            "criterion": "tumor-specific gene mutation",
1069
            "requirements": {
1070
                "presence": {
1071
                    "requirement_type": "presence",
1072
                    "groups": {
1073
                        "False": {
1074
                            "expected_value": false,
1075
                            "trial_ids": [
1076
                                "NCT00001148"
1077
                            ],
1078
                            "truth_value": "unknown"
1079
                        }
1080
                    }
1081
                }
1082
            }
1083
        },
1084
        "ovarian cancer": {
1085
            "criterion": "ovarian cancer",
1086
            "requirements": {
1087
                "confirmation method": {
1088
                    "requirement_type": "confirmation method",
1089
                    "groups": {
1090
                        "biopsy proven": {
1091
                            "expected_value": "biopsy proven",
1092
                            "trial_ids": [
1093
                                "NCT00001272"
1094
                            ],
1095
                            "truth_value": "unknown"
1096
                        }
1097
                    }
1098
                }
1099
            }
1100
        },
1101
        "evaluation location": {
1102
            "criterion": "evaluation location",
1103
            "requirements": {
1104
                "location": {
1105
                    "requirement_type": "location",
1106
                    "groups": {
1107
                        "Laboratory of Pathology, NCI": {
1108
                            "expected_value": "Laboratory of Pathology, NCI",
1109
                            "trial_ids": [
1110
                                "NCT00001272"
1111
                            ],
1112
                            "truth_value": "unknown"
1113
                        }
1114
                    }
1115
                }
1116
            }
1117
        },
1118
        "germ cell histology": {
1119
            "criterion": "germ cell histology",
1120
            "requirements": {
1121
                "presence": {
1122
                    "requirement_type": "presence",
1123
                    "groups": {
1124
                        "False": {
1125
                            "expected_value": false,
1126
                            "trial_ids": [
1127
                                "NCT00001272"
1128
                            ],
1129
                            "truth_value": "unknown"
1130
                        }
1131
                    }
1132
                }
1133
            }
1134
        },
1135
        "borderline histology": {
1136
            "criterion": "borderline histology",
1137
            "requirements": {
1138
                "presence": {
1139
                    "requirement_type": "presence",
1140
                    "groups": {
1141
                        "False": {
1142
                            "expected_value": false,
1143
                            "trial_ids": [
1144
                                "NCT00001272"
1145
                            ],
1146
                            "truth_value": "unknown"
1147
                        }
1148
                    }
1149
                }
1150
            }
1151
        },
1152
        "figo stage": {
1153
            "criterion": "figo stage",
1154
            "requirements": {
1155
                "stage": {
1156
                    "requirement_type": "stage",
1157
                    "groups": {
1158
                        "['III', 'IV']": {
1159
                            "expected_value": [
1160
                                "III",
1161
                                "IV"
1162
                            ],
1163
                            "trial_ids": [
1164
                                "NCT00001272"
1165
                            ],
1166
                            "truth_value": "unknown"
1167
                        },
1168
                        "IIC": {
1169
                            "expected_value": "IIC",
1170
                            "trial_ids": [
1171
                                "NCT00001272"
1172
                            ],
1173
                            "truth_value": "unknown"
1174
                        }
1175
                    }
1176
                },
1177
                "histology differentiation": {
1178
                    "requirement_type": "histology differentiation",
1179
                    "groups": {
1180
                        "poorly differentiated": {
1181
                            "expected_value": "poorly differentiated",
1182
                            "trial_ids": [
1183
                                "NCT00001272"
1184
                            ],
1185
                            "truth_value": "unknown"
1186
                        }
1187
                    }
1188
                }
1189
            }
1190
        },
1191
        "surgical debulking": {
1192
            "criterion": "surgical debulking",
1193
            "requirements": {
1194
                "procedure": {
1195
                    "requirement_type": "procedure",
1196
                    "groups": {
1197
                        "attempted": {
1198
                            "expected_value": "attempted",
1199
                            "trial_ids": [
1200
                                "NCT00001272"
1201
                            ],
1202
                            "truth_value": "unknown"
1203
                        }
1204
                    }
1205
                }
1206
            }
1207
        },
1208
        "performance status": {
1209
            "criterion": "performance status",
1210
            "requirements": {
1211
                "severity": {
1212
                    "requirement_type": "severity",
1213
                    "groups": {
1214
                        "operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=2 unit='ECOG'": {
1215
                            "expected_value": {
1216
                                "operator": "<=",
1217
                                "value": 2,
1218
                                "unit": "ECOG"
1219
                            },
1220
                            "trial_ids": [
1221
                                "NCT00001272"
1222
                            ],
1223
                            "truth_value": "unknown"
1224
                        }
1225
                    }
1226
                },
1227
                "scale": {
1228
                    "requirement_type": "scale",
1229
                    "groups": {
1230
                        "['ECOG', 'ZUBROD', 'WHO']": {
1231
                            "expected_value": [
1232
                                "ECOG",
1233
                                "ZUBROD",
1234
                                "WHO"
1235
                            ],
1236
                            "trial_ids": [
1237
                                "NCT00002620"
1238
                            ],
1239
                            "truth_value": "unknown"
1240
                        }
1241
                    }
1242
                },
1243
                "range": {
1244
                    "requirement_type": "range",
1245
                    "groups": {
1246
                        "comparisons=[LLMNumericalComparison(operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='>, value=0, unit='N/A'), LLMNumericalComparison(operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='>, value=2, unit='N/A')]": {
1247
                            "expected_value": {
1248
                                "comparisons": [
1249
                                    {
1250
                                        "operator": ">=",
1251
                                        "value": 0,
1252
                                        "unit": "N/A"
1253
                                    },
1254
                                    {
1255
                                        "operator": "<=",
1256
                                        "value": 2,
1257
                                        "unit": "N/A"
1258
                                    }
1259
                                ]
1260
                            },
1261
                            "trial_ids": [
1262
                                "NCT00002620"
1263
                            ],
1264
                            "truth_value": "unknown"
1265
                        }
1266
                    }
1267
                }
1268
            }
1269
        },
1270
        "end organ function": {
1271
            "criterion": "end organ function",
1272
            "requirements": {
1273
                "presence": {
1274
                    "requirement_type": "presence",
1275
                    "groups": {
1276
                        "True": {
1277
                            "expected_value": true,
1278
                            "trial_ids": [
1279
                                "NCT00001272"
1280
                            ],
1281
                            "truth_value": "unknown"
1282
                        }
1283
                    }
1284
                }
1285
            }
1286
        },
1287
        "brain involvement": {
1288
            "criterion": "brain involvement",
1289
            "requirements": {
1290
                "presence": {
1291
                    "requirement_type": "presence",
1292
                    "groups": {
1293
                        "False": {
1294
                            "expected_value": false,
1295
                            "trial_ids": [
1296
                                "NCT00001272"
1297
                            ],
1298
                            "truth_value": "unknown"
1299
                        }
1300
                    }
1301
                }
1302
            }
1303
        },
1304
        "myocardial infarction": {
1305
            "criterion": "myocardial infarction",
1306
            "requirements": {
1307
                "history": {
1308
                    "requirement_type": "history",
1309
                    "groups": {
1310
                        "False": {
1311
                            "expected_value": false,
1312
                            "trial_ids": [
1313
                                "NCT00001272"
1314
                            ],
1315
                            "truth_value": "unknown"
1316
                        }
1317
                    }
1318
                }
1319
            }
1320
        },
1321
        "cardiac arrhythmias": {
1322
            "criterion": "cardiac arrhythmias",
1323
            "requirements": {
1324
                "treatment": {
1325
                    "requirement_type": "treatment",
1326
                    "groups": {
1327
                        "False": {
1328
                            "expected_value": false,
1329
                            "trial_ids": [
1330
                                "NCT00001272"
1331
                            ],
1332
                            "truth_value": "unknown"
1333
                        }
1334
                    }
1335
                }
1336
            }
1337
        },
1338
        "right bundle branch block": {
1339
            "criterion": "right bundle branch block",
1340
            "requirements": {
1341
                "presence": {
1342
                    "requirement_type": "presence",
1343
                    "groups": {
1344
                        "True": {
1345
                            "expected_value": true,
1346
                            "trial_ids": [
1347
                                "NCT00001272"
1348
                            ],
1349
                            "truth_value": "unknown"
1350
                        }
1351
                    }
1352
                }
1353
            }
1354
        },
1355
        "left anterior hemiblock": {
1356
            "criterion": "left anterior hemiblock",
1357
            "requirements": {
1358
                "presence": {
1359
                    "requirement_type": "presence",
1360
                    "groups": {
1361
                        "True": {
1362
                            "expected_value": true,
1363
                            "trial_ids": [
1364
                                "NCT00001272"
1365
                            ],
1366
                            "truth_value": "unknown"
1367
                        }
1368
                    }
1369
                }
1370
            }
1371
        },
1372
        "left bundle branch block": {
1373
            "criterion": "left bundle branch block",
1374
            "requirements": {
1375
                "presence": {
1376
                    "requirement_type": "presence",
1377
                    "groups": {
1378
                        "True": {
1379
                            "expected_value": true,
1380
                            "trial_ids": [
1381
                                "NCT00001272"
1382
                            ],
1383
                            "truth_value": "unknown"
1384
                        }
1385
                    }
1386
                }
1387
            }
1388
        },
1389
        "creatinine clearance": {
1390
            "criterion": "creatinine clearance",
1391
            "requirements": {
1392
                "quantity": {
1393
                    "requirement_type": "quantity",
1394
                    "groups": {
1395
                        "operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=60 unit='cc/min'": {
1396
                            "expected_value": {
1397
                                "operator": ">=",
1398
                                "value": 60,
1399
                                "unit": "cc/min"
1400
                            },
1401
                            "trial_ids": [
1402
                                "NCT00001272"
1403
                            ],
1404
                            "truth_value": "unknown"
1405
                        }
1406
                    }
1407
                },
1408
                "minimum clearance": {
1409
                    "requirement_type": "minimum clearance",
1410
                    "groups": {
1411
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=70 unit='ml/min'": {
1412
                            "expected_value": {
1413
                                "operator": ">",
1414
                                "value": 70,
1415
                                "unit": "ml/min"
1416
                            },
1417
                            "trial_ids": [
1418
                                "NCT00002620"
1419
                            ],
1420
                            "truth_value": "unknown"
1421
                        }
1422
                    }
1423
                }
1424
            }
1425
        },
1426
        "ureteral obstruction": {
1427
            "criterion": "ureteral obstruction",
1428
            "requirements": {
1429
                "presence": {
1430
                    "requirement_type": "presence",
1431
                    "groups": {
1432
                        "False": {
1433
                            "expected_value": false,
1434
                            "trial_ids": [
1435
                                "NCT00001272"
1436
                            ],
1437
                            "truth_value": "unknown"
1438
                        }
1439
                    }
1440
                }
1441
            }
1442
        },
1443
        "hepatic function": {
1444
            "criterion": "hepatic function",
1445
            "requirements": {
1446
                "coagulation parameters": {
1447
                    "requirement_type": "coagulation parameters",
1448
                    "groups": {
1449
                        "normal": {
1450
                            "expected_value": "normal",
1451
                            "trial_ids": [
1452
                                "NCT00001272"
1453
                            ],
1454
                            "truth_value": "unknown"
1455
                        }
1456
                    }
1457
                }
1458
            }
1459
        },
1460
        "serum transaminases": {
1461
            "criterion": "serum transaminases",
1462
            "requirements": {
1463
                "level": {
1464
                    "requirement_type": "level",
1465
                    "groups": {
1466
                        "operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=3 unit='times upper limit of normal'": {
1467
                            "expected_value": {
1468
                                "operator": "<=",
1469
                                "value": 3,
1470
                                "unit": "times upper limit of normal"
1471
                            },
1472
                            "trial_ids": [
1473
                                "NCT00001272"
1474
                            ],
1475
                            "truth_value": "unknown"
1476
                        }
1477
                    }
1478
                }
1479
            }
1480
        },
1481
        "neurologic function": {
1482
            "criterion": "neurologic function",
1483
            "requirements": {
1484
                "severity": {
1485
                    "requirement_type": "severity",
1486
                    "groups": {
1487
                        "operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=1 unit='grade'": {
1488
                            "expected_value": {
1489
                                "operator": "<=",
1490
                                "value": 1,
1491
                                "unit": "grade"
1492
                            },
1493
                            "trial_ids": [
1494
                                "NCT00001272"
1495
                            ],
1496
                            "truth_value": "unknown"
1497
                        }
1498
                    }
1499
                }
1500
            }
1501
        },
1502
        "active gi bleeding": {
1503
            "criterion": "active gi bleeding",
1504
            "requirements": {
1505
                "history": {
1506
                    "requirement_type": "history",
1507
                    "groups": {
1508
                        "False": {
1509
                            "expected_value": false,
1510
                            "trial_ids": [
1511
                                "NCT00001272"
1512
                            ],
1513
                            "truth_value": "unknown"
1514
                        }
1515
                    }
1516
                }
1517
            }
1518
        },
1519
        "total granulocyte count": {
1520
            "criterion": "total granulocyte count",
1521
            "requirements": {
1522
                "quantity": {
1523
                    "requirement_type": "quantity",
1524
                    "groups": {
1525
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=2000 unit='N/A'": {
1526
                            "expected_value": {
1527
                                "operator": ">",
1528
                                "value": 2000,
1529
                                "unit": "N/A"
1530
                            },
1531
                            "trial_ids": [
1532
                                "NCT00001272"
1533
                            ],
1534
                            "truth_value": "unknown"
1535
                        }
1536
                    }
1537
                }
1538
            }
1539
        },
1540
        "prior history of invasive malignancy": {
1541
            "criterion": "prior history of invasive malignancy",
1542
            "requirements": {
1543
                "presence": {
1544
                    "requirement_type": "presence",
1545
                    "groups": {
1546
                        "False": {
1547
                            "expected_value": false,
1548
                            "trial_ids": [
1549
                                "NCT00001272"
1550
                            ],
1551
                            "truth_value": "unknown"
1552
                        }
1553
                    }
1554
                }
1555
            }
1556
        },
1557
        "nonmelanoma skin cancer": {
1558
            "criterion": "nonmelanoma skin cancer",
1559
            "requirements": {
1560
                "treatment status": {
1561
                    "requirement_type": "treatment status",
1562
                    "groups": {
1563
                        "curatively treated": {
1564
                            "expected_value": "curatively treated",
1565
                            "trial_ids": [
1566
                                "NCT00001272"
1567
                            ],
1568
                            "truth_value": "unknown"
1569
                        }
1570
                    }
1571
                }
1572
            }
1573
        },
1574
        "willingness to meet protocol requirements": {
1575
            "criterion": "willingness to meet protocol requirements",
1576
            "requirements": {
1577
                "willingness": {
1578
                    "requirement_type": "willingness",
1579
                    "groups": {
1580
                        "True": {
1581
                            "expected_value": true,
1582
                            "trial_ids": [
1583
                                "NCT00001272"
1584
                            ],
1585
                            "truth_value": "unknown"
1586
                        }
1587
                    }
1588
                }
1589
            }
1590
        },
1591
        "therapy initiation time": {
1592
            "criterion": "therapy initiation time",
1593
            "requirements": {
1594
                "time frame": {
1595
                    "requirement_type": "time frame",
1596
                    "groups": {
1597
                        "operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=8 unit='weeks'": {
1598
                            "expected_value": {
1599
                                "operator": "<=",
1600
                                "value": 8,
1601
                                "unit": "weeks"
1602
                            },
1603
                            "trial_ids": [
1604
                                "NCT00001272"
1605
                            ],
1606
                            "truth_value": "unknown"
1607
                        }
1608
                    }
1609
                }
1610
            }
1611
        },
1612
        "central venous catheter": {
1613
            "criterion": "central venous catheter",
1614
            "requirements": {
1615
                "placement": {
1616
                    "requirement_type": "placement",
1617
                    "groups": {
1618
                        "True": {
1619
                            "expected_value": true,
1620
                            "trial_ids": [
1621
                                "NCT00001272"
1622
                            ],
1623
                            "truth_value": "unknown"
1624
                        }
1625
                    }
1626
                }
1627
            }
1628
        },
1629
        "registration": {
1630
            "criterion": "registration",
1631
            "requirements": {
1632
                "method": {
1633
                    "requirement_type": "method",
1634
                    "groups": {
1635
                        "calling": {
1636
                            "expected_value": "calling",
1637
                            "trial_ids": [
1638
                                "NCT00001272"
1639
                            ],
1640
                            "truth_value": "unknown"
1641
                        }
1642
                    }
1643
                },
1644
                "contact": {
1645
                    "requirement_type": "contact",
1646
                    "groups": {
1647
                        "Orkand Corporation at 402-1732": {
1648
                            "expected_value": "Orkand Corporation at 402-1732",
1649
                            "trial_ids": [
1650
                                "NCT00001272"
1651
                            ],
1652
                            "truth_value": "unknown"
1653
                        }
1654
                    }
1655
                },
1656
                "time": {
1657
                    "requirement_type": "time",
1658
                    "groups": {
1659
                        "comparisons=[LLMNumericalComparison(operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='>, value=8.5, unit='hours'), LLMNumericalComparison(operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='>, value=17, unit='hours')]": {
1660
                            "expected_value": {
1661
                                "comparisons": [
1662
                                    {
1663
                                        "operator": ">=",
1664
                                        "value": 8.5,
1665
                                        "unit": "hours"
1666
                                    },
1667
                                    {
1668
                                        "operator": "<=",
1669
                                        "value": 17,
1670
                                        "unit": "hours"
1671
                                    }
1672
                                ]
1673
                            },
1674
                            "trial_ids": [
1675
                                "NCT00001272"
1676
                            ],
1677
                            "truth_value": "unknown"
1678
                        }
1679
                    }
1680
                }
1681
            }
1682
        },
1683
        "medical condition": {
1684
            "criterion": "medical condition",
1685
            "requirements": {
1686
                "worsened by apheresis": {
1687
                    "requirement_type": "worsened by apheresis",
1688
                    "groups": {
1689
                        "False": {
1690
                            "expected_value": false,
1691
                            "trial_ids": [
1692
                                "NCT00001582"
1693
                            ],
1694
                            "truth_value": "unknown"
1695
                        }
1696
                    }
1697
                }
1698
            }
1699
        },
1700
        "congestive heart failure": {
1701
            "criterion": "congestive heart failure",
1702
            "requirements": {
1703
                "presence": {
1704
                    "requirement_type": "presence",
1705
                    "groups": {
1706
                        "True": {
1707
                            "expected_value": true,
1708
                            "trial_ids": [
1709
                                "NCT00001582"
1710
                            ],
1711
                            "truth_value": "unknown"
1712
                        }
1713
                    }
1714
                }
1715
            }
1716
        },
1717
        "angina": {
1718
            "criterion": "angina",
1719
            "requirements": {
1720
                "history": {
1721
                    "requirement_type": "history",
1722
                    "groups": {
1723
                        "True": {
1724
                            "expected_value": true,
1725
                            "trial_ids": [
1726
                                "NCT00001582"
1727
                            ],
1728
                            "truth_value": "unknown"
1729
                        }
1730
                    }
1731
                }
1732
            }
1733
        },
1734
        "hypotension": {
1735
            "criterion": "hypotension",
1736
            "requirements": {
1737
                "severity": {
1738
                    "requirement_type": "severity",
1739
                    "groups": {
1740
                        "severe": {
1741
                            "expected_value": "severe",
1742
                            "trial_ids": [
1743
                                "NCT00001582"
1744
                            ],
1745
                            "truth_value": "unknown"
1746
                        }
1747
                    }
1748
                }
1749
            }
1750
        },
1751
        "hypertension": {
1752
            "criterion": "hypertension",
1753
            "requirements": {
1754
                "control": {
1755
                    "requirement_type": "control",
1756
                    "groups": {
1757
                        "poorly controlled": {
1758
                            "expected_value": "poorly controlled",
1759
                            "trial_ids": [
1760
                                "NCT00001582"
1761
                            ],
1762
                            "truth_value": "unknown"
1763
                        }
1764
                    }
1765
                }
1766
            }
1767
        },
1768
        "blood pressure": {
1769
            "criterion": "blood pressure",
1770
            "requirements": {
1771
                "average baseline": {
1772
                    "requirement_type": "average baseline",
1773
                    "groups": {
1774
                        "comparisons=[LLMNumericalComparison(operator=<LLMOperator.GREATER_THAN: '>'>, value=160, unit='mmHg'), LLMNumericalComparison(operator=<LLMOperator.GREATER_THAN: '>'>, value=90, unit='mmHg')]": {
1775
                            "expected_value": {
1776
                                "comparisons": [
1777
                                    {
1778
                                        "operator": ">",
1779
                                        "value": 160,
1780
                                        "unit": "mmHg"
1781
                                    },
1782
                                    {
1783
                                        "operator": ">",
1784
                                        "value": 90,
1785
                                        "unit": "mmHg"
1786
                                    }
1787
                                ]
1788
                            },
1789
                            "trial_ids": [
1790
                                "NCT00001582"
1791
                            ],
1792
                            "truth_value": "unknown"
1793
                        }
1794
                    }
1795
                },
1796
                "status": {
1797
                    "requirement_type": "status",
1798
                    "groups": {
1799
                        "normotensive": {
1800
                            "expected_value": "normotensive",
1801
                            "trial_ids": [
1802
                                "NCT00001748"
1803
                            ],
1804
                            "truth_value": "unknown"
1805
                        }
1806
                    }
1807
                }
1808
            }
1809
        },
1810
        "coagulation protein disorder": {
1811
            "criterion": "coagulation protein disorder",
1812
            "requirements": {
1813
                "history": {
1814
                    "requirement_type": "history",
1815
                    "groups": {
1816
                        "True": {
1817
                            "expected_value": true,
1818
                            "trial_ids": [
1819
                                "NCT00001582"
1820
                            ],
1821
                            "truth_value": "unknown"
1822
                        }
1823
                    }
1824
                }
1825
            }
1826
        },
1827
        "apheresis": {
1828
            "criterion": "apheresis",
1829
            "requirements": {
1830
                "eligibility": {
1831
                    "requirement_type": "eligibility",
1832
                    "groups": {
1833
                        "False": {
1834
                            "expected_value": false,
1835
                            "trial_ids": [
1836
                                "NCT00001582"
1837
                            ],
1838
                            "truth_value": "unknown"
1839
                        }
1840
                    }
1841
                },
1842
                "desire": {
1843
                    "requirement_type": "desire",
1844
                    "groups": {
1845
                        "True": {
1846
                            "expected_value": true,
1847
                            "trial_ids": [
1848
                                "NCT00001582"
1849
                            ],
1850
                            "truth_value": "unknown"
1851
                        }
1852
                    }
1853
                },
1854
                "necessity": {
1855
                    "requirement_type": "necessity",
1856
                    "groups": {
1857
                        "True": {
1858
                            "expected_value": true,
1859
                            "trial_ids": [
1860
                                "NCT00001582"
1861
                            ],
1862
                            "truth_value": "unknown"
1863
                        }
1864
                    }
1865
                }
1866
            }
1867
        },
1868
        "disorder of the immune system": {
1869
            "criterion": "disorder of the immune system",
1870
            "requirements": {
1871
                "presence": {
1872
                    "requirement_type": "presence",
1873
                    "groups": {
1874
                        "True": {
1875
                            "expected_value": true,
1876
                            "trial_ids": [
1877
                                "NCT00001582"
1878
                            ],
1879
                            "truth_value": "unknown"
1880
                        }
1881
                    }
1882
                }
1883
            }
1884
        },
1885
        "cancer": {
1886
            "criterion": "cancer",
1887
            "requirements": {
1888
                "presence": {
1889
                    "requirement_type": "presence",
1890
                    "groups": {
1891
                        "True": {
1892
                            "expected_value": true,
1893
                            "trial_ids": [
1894
                                "NCT00001582"
1895
                            ],
1896
                            "truth_value": "unknown"
1897
                        }
1898
                    }
1899
                }
1900
            }
1901
        },
1902
        "autoimmune disorder": {
1903
            "criterion": "autoimmune disorder",
1904
            "requirements": {
1905
                "carrier status": {
1906
                    "requirement_type": "carrier status",
1907
                    "groups": {
1908
                        "True": {
1909
                            "expected_value": true,
1910
                            "trial_ids": [
1911
                                "NCT00001582"
1912
                            ],
1913
                            "truth_value": "unknown"
1914
                        }
1915
                    }
1916
                }
1917
            }
1918
        },
1919
        "immunodeficiency disease": {
1920
            "criterion": "immunodeficiency disease",
1921
            "requirements": {
1922
                "carrier status": {
1923
                    "requirement_type": "carrier status",
1924
                    "groups": {
1925
                        "True": {
1926
                            "expected_value": true,
1927
                            "trial_ids": [
1928
                                "NCT00001582"
1929
                            ],
1930
                            "truth_value": "unknown"
1931
                        }
1932
                    }
1933
                }
1934
            }
1935
        },
1936
        "x-linked severe combined immunodeficiency": {
1937
            "criterion": "x-linked severe combined immunodeficiency",
1938
            "requirements": {
1939
                "presence": {
1940
                    "requirement_type": "presence",
1941
                    "groups": {
1942
                        "True": {
1943
                            "expected_value": true,
1944
                            "trial_ids": [
1945
                                "NCT00001582"
1946
                            ],
1947
                            "truth_value": "unknown"
1948
                        }
1949
                    }
1950
                }
1951
            }
1952
        },
1953
        "scid": {
1954
            "criterion": "scid",
1955
            "requirements": {
1956
                "inheritance pattern": {
1957
                    "requirement_type": "inheritance pattern",
1958
                    "groups": {
1959
                        "autosomal recessive": {
1960
                            "expected_value": "autosomal recessive",
1961
                            "trial_ids": [
1962
                                "NCT00001582"
1963
                            ],
1964
                            "truth_value": "unknown"
1965
                        }
1966
                    }
1967
                }
1968
            }
1969
        },
1970
        "x-linked cd40 ligand deficiency": {
1971
            "criterion": "x-linked cd40 ligand deficiency",
1972
            "requirements": {
1973
                "presence": {
1974
                    "requirement_type": "presence",
1975
                    "groups": {
1976
                        "True": {
1977
                            "expected_value": true,
1978
                            "trial_ids": [
1979
                                "NCT00001582"
1980
                            ],
1981
                            "truth_value": "unknown"
1982
                        }
1983
                    }
1984
                }
1985
            }
1986
        },
1987
        "common variable immunodeficiency": {
1988
            "criterion": "common variable immunodeficiency",
1989
            "requirements": {
1990
                "presence": {
1991
                    "requirement_type": "presence",
1992
                    "groups": {
1993
                        "True": {
1994
                            "expected_value": true,
1995
                            "trial_ids": [
1996
                                "NCT00001582"
1997
                            ],
1998
                            "truth_value": "unknown"
1999
                        }
2000
                    }
2001
                }
2002
            }
2003
        },
2004
        "ataxia-telangiectasia": {
2005
            "criterion": "ataxia-telangiectasia",
2006
            "requirements": {
2007
                "presence": {
2008
                    "requirement_type": "presence",
2009
                    "groups": {
2010
                        "True": {
2011
                            "expected_value": true,
2012
                            "trial_ids": [
2013
                                "NCT00001582"
2014
                            ],
2015
                            "truth_value": "unknown"
2016
                        }
2017
                    }
2018
                }
2019
            }
2020
        },
2021
        "wiskott aldrich syndrome": {
2022
            "criterion": "wiskott aldrich syndrome",
2023
            "requirements": {
2024
                "presence": {
2025
                    "requirement_type": "presence",
2026
                    "groups": {
2027
                        "True": {
2028
                            "expected_value": true,
2029
                            "trial_ids": [
2030
                                "NCT00001582"
2031
                            ],
2032
                            "truth_value": "unknown"
2033
                        }
2034
                    }
2035
                }
2036
            }
2037
        },
2038
        "digeorge syndrome": {
2039
            "criterion": "digeorge syndrome",
2040
            "requirements": {
2041
                "presence": {
2042
                    "requirement_type": "presence",
2043
                    "groups": {
2044
                        "True": {
2045
                            "expected_value": true,
2046
                            "trial_ids": [
2047
                                "NCT00001582"
2048
                            ],
2049
                            "truth_value": "unknown"
2050
                        }
2051
                    }
2052
                }
2053
            }
2054
        },
2055
        "htlv-1 infection": {
2056
            "criterion": "htlv-1 infection",
2057
            "requirements": {
2058
                "presence": {
2059
                    "requirement_type": "presence",
2060
                    "groups": {
2061
                        "True": {
2062
                            "expected_value": true,
2063
                            "trial_ids": [
2064
                                "NCT00001582"
2065
                            ],
2066
                            "truth_value": "unknown"
2067
                        }
2068
                    }
2069
                }
2070
            }
2071
        },
2072
        "understanding ability": {
2073
            "criterion": "understanding ability",
2074
            "requirements": {
2075
                "ability": {
2076
                    "requirement_type": "ability",
2077
                    "groups": {
2078
                        "True": {
2079
                            "expected_value": true,
2080
                            "trial_ids": [
2081
                                "NCT00001582"
2082
                            ],
2083
                            "truth_value": "unknown"
2084
                        }
2085
                    }
2086
                }
2087
            }
2088
        },
2089
        "informed consent signing": {
2090
            "criterion": "informed consent signing",
2091
            "requirements": {
2092
                "ability": {
2093
                    "requirement_type": "ability",
2094
                    "groups": {
2095
                        "True": {
2096
                            "expected_value": true,
2097
                            "trial_ids": [
2098
                                "NCT00001582"
2099
                            ],
2100
                            "truth_value": "unknown"
2101
                        }
2102
                    }
2103
                }
2104
            }
2105
        },
2106
        "hematocrit": {
2107
            "criterion": "hematocrit",
2108
            "requirements": {
2109
                "level": {
2110
                    "requirement_type": "level",
2111
                    "groups": {
2112
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=28 unit='%'": {
2113
                            "expected_value": {
2114
                                "operator": ">",
2115
                                "value": 28,
2116
                                "unit": "%"
2117
                            },
2118
                            "trial_ids": [
2119
                                "NCT00001582"
2120
                            ],
2121
                            "truth_value": "unknown"
2122
                        }
2123
                    }
2124
                },
2125
                "minimum percentage": {
2126
                    "requirement_type": "minimum percentage",
2127
                    "groups": {
2128
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=30 unit='%'": {
2129
                            "expected_value": {
2130
                                "operator": ">",
2131
                                "value": 30,
2132
                                "unit": "%"
2133
                            },
2134
                            "trial_ids": [
2135
                                "NCT00002620"
2136
                            ],
2137
                            "truth_value": "unknown"
2138
                        }
2139
                    }
2140
                }
2141
            }
2142
        },
2143
        "counts": {
2144
            "criterion": "counts",
2145
            "requirements": {
2146
                "comparison": {
2147
                    "requirement_type": "comparison",
2148
                    "groups": {
2149
                        "lower than those above": {
2150
                            "expected_value": "lower than those above",
2151
                            "trial_ids": [
2152
                                "NCT00001582"
2153
                            ],
2154
                            "truth_value": "unknown"
2155
                        }
2156
                    }
2157
                }
2158
            }
2159
        },
2160
        "weight": {
2161
            "criterion": "weight",
2162
            "requirements": {
2163
                "quantity": {
2164
                    "requirement_type": "quantity",
2165
                    "groups": {
2166
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=25 unit='kg'": {
2167
                            "expected_value": {
2168
                                "operator": ">",
2169
                                "value": 25,
2170
                                "unit": "kg"
2171
                            },
2172
                            "trial_ids": [
2173
                                "NCT00001582"
2174
                            ],
2175
                            "truth_value": "unknown"
2176
                        }
2177
                    }
2178
                }
2179
            }
2180
        },
2181
        "overall health": {
2182
            "criterion": "overall health",
2183
            "requirements": {
2184
                "status": {
2185
                    "requirement_type": "status",
2186
                    "groups": {
2187
                        "N/A": {
2188
                            "expected_value": "N/A",
2189
                            "trial_ids": [
2190
                                "NCT00001582"
2191
                            ],
2192
                            "truth_value": "unknown"
2193
                        }
2194
                    }
2195
                }
2196
            }
2197
        },
2198
        "chronic myelogenous leukemia": {
2199
            "criterion": "chronic myelogenous leukemia",
2200
            "requirements": {
2201
                "presence": {
2202
                    "requirement_type": "presence",
2203
                    "groups": {
2204
                        "True": {
2205
                            "expected_value": true,
2206
                            "trial_ids": [
2207
                                "NCT00001748"
2208
                            ],
2209
                            "truth_value": "unknown"
2210
                        }
2211
                    }
2212
                }
2213
            }
2214
        },
2215
        "leukemia phase": {
2216
            "criterion": "leukemia phase",
2217
            "requirements": {
2218
                "category": {
2219
                    "requirement_type": "category",
2220
                    "groups": {
2221
                        "accelerated phase": {
2222
                            "expected_value": "accelerated phase",
2223
                            "trial_ids": [
2224
                                "NCT00001748"
2225
                            ],
2226
                            "truth_value": "unknown"
2227
                        },
2228
                        "blast transformation": {
2229
                            "expected_value": "blast transformation",
2230
                            "trial_ids": [
2231
                                "NCT00001748"
2232
                            ],
2233
                            "truth_value": "unknown"
2234
                        }
2235
                    }
2236
                }
2237
            }
2238
        },
2239
        "acute lymphoblastic leukemia": {
2240
            "criterion": "acute lymphoblastic leukemia",
2241
            "requirements": {
2242
                "presence": {
2243
                    "requirement_type": "presence",
2244
                    "groups": {
2245
                        "True": {
2246
                            "expected_value": true,
2247
                            "trial_ids": [
2248
                                "NCT00001748"
2249
                            ],
2250
                            "truth_value": "unknown"
2251
                        }
2252
                    }
2253
                }
2254
            }
2255
        },
2256
        "remission status": {
2257
            "criterion": "remission status",
2258
            "requirements": {
2259
                "status": {
2260
                    "requirement_type": "status",
2261
                    "groups": {
2262
                        "any remission": {
2263
                            "expected_value": "any remission",
2264
                            "trial_ids": [
2265
                                "NCT00001748"
2266
                            ],
2267
                            "truth_value": "unknown"
2268
                        }
2269
                    }
2270
                }
2271
            }
2272
        },
2273
        "high-risk features": {
2274
            "criterion": "high-risk features",
2275
            "requirements": {
2276
                "presence": {
2277
                    "requirement_type": "presence",
2278
                    "groups": {
2279
                        "True": {
2280
                            "expected_value": true,
2281
                            "trial_ids": [
2282
                                "NCT00001748"
2283
                            ],
2284
                            "truth_value": "unknown"
2285
                        }
2286
                    }
2287
                }
2288
            }
2289
        },
2290
        "leukocyte count": {
2291
            "criterion": "leukocyte count",
2292
            "requirements": {
2293
                "count": {
2294
                    "requirement_type": "count",
2295
                    "groups": {
2296
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=100000 unit='cu mm'": {
2297
                            "expected_value": {
2298
                                "operator": ">",
2299
                                "value": 100000,
2300
                                "unit": "cu mm"
2301
                            },
2302
                            "trial_ids": [
2303
                                "NCT00001748"
2304
                            ],
2305
                            "truth_value": "unknown"
2306
                        }
2307
                    }
2308
                }
2309
            }
2310
        },
2311
        "karyotypes": {
2312
            "criterion": "karyotypes",
2313
            "requirements": {
2314
                "specific karyotypes": {
2315
                    "requirement_type": "specific karyotypes",
2316
                    "groups": {
2317
                        "['t9; 22', 't4', 't19', 't11']": {
2318
                            "expected_value": [
2319
                                "t9; 22",
2320
                                "t4",
2321
                                "t19",
2322
                                "t11"
2323
                            ],
2324
                            "trial_ids": [
2325
                                "NCT00001748"
2326
                            ],
2327
                            "truth_value": "unknown"
2328
                        }
2329
                    }
2330
                }
2331
            }
2332
        },
2333
        "biphenotypic leukemia": {
2334
            "criterion": "biphenotypic leukemia",
2335
            "requirements": {
2336
                "presence": {
2337
                    "requirement_type": "presence",
2338
                    "groups": {
2339
                        "True": {
2340
                            "expected_value": true,
2341
                            "trial_ids": [
2342
                                "NCT00001748"
2343
                            ],
2344
                            "truth_value": "unknown"
2345
                        }
2346
                    }
2347
                }
2348
            }
2349
        },
2350
        "second remission": {
2351
            "criterion": "second remission",
2352
            "requirements": {
2353
                "status": {
2354
                    "requirement_type": "status",
2355
                    "groups": {
2356
                        "all": {
2357
                            "expected_value": "all",
2358
                            "trial_ids": [
2359
                                "NCT00001748"
2360
                            ],
2361
                            "truth_value": "unknown"
2362
                        }
2363
                    }
2364
                }
2365
            }
2366
        },
2367
        "primary induction failure": {
2368
            "criterion": "primary induction failure",
2369
            "requirements": {
2370
                "status": {
2371
                    "requirement_type": "status",
2372
                    "groups": {
2373
                        "True": {
2374
                            "expected_value": true,
2375
                            "trial_ids": [
2376
                                "NCT00001748"
2377
                            ],
2378
                            "truth_value": "unknown"
2379
                        }
2380
                    }
2381
                }
2382
            }
2383
        },
2384
        "partial remission": {
2385
            "criterion": "partial remission",
2386
            "requirements": {
2387
                "status": {
2388
                    "requirement_type": "status",
2389
                    "groups": {
2390
                        "True": {
2391
                            "expected_value": true,
2392
                            "trial_ids": [
2393
                                "NCT00001748"
2394
                            ],
2395
                            "truth_value": "unknown"
2396
                        }
2397
                    }
2398
                }
2399
            }
2400
        },
2401
        "response status": {
2402
            "criterion": "response status",
2403
            "requirements": {
2404
                "status": {
2405
                    "requirement_type": "status",
2406
                    "groups": {
2407
                        "partially responding": {
2408
                            "expected_value": "partially responding",
2409
                            "trial_ids": [
2410
                                "NCT00001748"
2411
                            ],
2412
                            "truth_value": "unknown"
2413
                        }
2414
                    }
2415
                }
2416
            }
2417
        },
2418
        "untreated relapse": {
2419
            "criterion": "untreated relapse",
2420
            "requirements": {
2421
                "status": {
2422
                    "requirement_type": "status",
2423
                    "groups": {
2424
                        "True": {
2425
                            "expected_value": true,
2426
                            "trial_ids": [
2427
                                "NCT00001748"
2428
                            ],
2429
                            "truth_value": "unknown"
2430
                        }
2431
                    }
2432
                }
2433
            }
2434
        },
2435
        "acute myelogenous leukemia (aml)": {
2436
            "criterion": "acute myelogenous leukemia (aml)",
2437
            "requirements": {
2438
                "condition": {
2439
                    "requirement_type": "condition",
2440
                    "groups": {
2441
                        "second or subsequent remission": {
2442
                            "expected_value": "second or subsequent remission",
2443
                            "trial_ids": [
2444
                                "NCT00001748"
2445
                            ],
2446
                            "truth_value": "unknown"
2447
                        },
2448
                        "primary induction failure": {
2449
                            "expected_value": "primary induction failure",
2450
                            "trial_ids": [
2451
                                "NCT00001748"
2452
                            ],
2453
                            "truth_value": "unknown"
2454
                        },
2455
                        "partial remission": {
2456
                            "expected_value": "partial remission",
2457
                            "trial_ids": [
2458
                                "NCT00001748"
2459
                            ],
2460
                            "truth_value": "unknown"
2461
                        },
2462
                        "resistant relapse": {
2463
                            "expected_value": "resistant relapse",
2464
                            "trial_ids": [
2465
                                "NCT00001748"
2466
                            ],
2467
                            "truth_value": "unknown"
2468
                        }
2469
                    }
2470
                }
2471
            }
2472
        },
2473
        "myelodysplastic syndromes": {
2474
            "criterion": "myelodysplastic syndromes",
2475
            "requirements": {
2476
                "categories": {
2477
                    "requirement_type": "categories",
2478
                    "groups": {
2479
                        "['refractory anemia with excess of blasts']": {
2480
                            "expected_value": [
2481
                                "refractory anemia with excess of blasts"
2482
                            ],
2483
                            "trial_ids": [
2484
                                "NCT00001748"
2485
                            ],
2486
                            "truth_value": "unknown"
2487
                        },
2488
                        "['transformation to acute leukemia']": {
2489
                            "expected_value": [
2490
                                "transformation to acute leukemia"
2491
                            ],
2492
                            "trial_ids": [
2493
                                "NCT00001748"
2494
                            ],
2495
                            "truth_value": "unknown"
2496
                        },
2497
                        "['chronic myelomonocytic leukemia']": {
2498
                            "expected_value": [
2499
                                "chronic myelomonocytic leukemia"
2500
                            ],
2501
                            "trial_ids": [
2502
                                "NCT00001748"
2503
                            ],
2504
                            "truth_value": "unknown"
2505
                        }
2506
                    }
2507
                }
2508
            }
2509
        },
2510
        "myeloproliferative disorders": {
2511
            "criterion": "myeloproliferative disorders",
2512
            "requirements": {
2513
                "transformation stage": {
2514
                    "requirement_type": "transformation stage",
2515
                    "groups": {
2516
                        "terminal": {
2517
                            "expected_value": "terminal",
2518
                            "trial_ids": [
2519
                                "NCT00001748"
2520
                            ],
2521
                            "truth_value": "unknown"
2522
                        }
2523
                    }
2524
                }
2525
            }
2526
        },
2527
        "chronic lymphocytic leukemia": {
2528
            "criterion": "chronic lymphocytic leukemia",
2529
            "requirements": {
2530
                "presence": {
2531
                    "requirement_type": "presence",
2532
                    "groups": {
2533
                        "True": {
2534
                            "expected_value": true,
2535
                            "trial_ids": [
2536
                                "NCT00001748"
2537
                            ],
2538
                            "truth_value": "unknown"
2539
                        }
2540
                    }
2541
                }
2542
            }
2543
        },
2544
        "richter transformation": {
2545
            "criterion": "richter transformation",
2546
            "requirements": {
2547
                "presence": {
2548
                    "requirement_type": "presence",
2549
                    "groups": {
2550
                        "True": {
2551
                            "expected_value": true,
2552
                            "trial_ids": [
2553
                                "NCT00001748"
2554
                            ],
2555
                            "truth_value": "unknown"
2556
                        }
2557
                    }
2558
                }
2559
            }
2560
        },
2561
        "lymphoma": {
2562
            "criterion": "lymphoma",
2563
            "requirements": {
2564
                "grade": {
2565
                    "requirement_type": "grade",
2566
                    "groups": {
2567
                        "high": {
2568
                            "expected_value": "high",
2569
                            "trial_ids": [
2570
                                "NCT00001748"
2571
                            ],
2572
                            "truth_value": "unknown"
2573
                        }
2574
                    }
2575
                }
2576
            }
2577
        },
2578
        "treatment response": {
2579
            "criterion": "treatment response",
2580
            "requirements": {
2581
                "response": {
2582
                    "requirement_type": "response",
2583
                    "groups": {
2584
                        "refractory": {
2585
                            "expected_value": "refractory",
2586
                            "trial_ids": [
2587
                                "NCT00001748"
2588
                            ],
2589
                            "truth_value": "unknown"
2590
                        }
2591
                    }
2592
                }
2593
            }
2594
        },
2595
        "lymphoma subtype": {
2596
            "criterion": "lymphoma subtype",
2597
            "requirements": {
2598
                "subtype": {
2599
                    "requirement_type": "subtype",
2600
                    "groups": {
2601
                        "mantle cell": {
2602
                            "expected_value": "mantle cell",
2603
                            "trial_ids": [
2604
                                "NCT00001748"
2605
                            ],
2606
                            "truth_value": "unknown"
2607
                        }
2608
                    }
2609
                }
2610
            }
2611
        },
2612
        "major organ dysfunction": {
2613
            "criterion": "major organ dysfunction",
2614
            "requirements": {
2615
                "presence": {
2616
                    "requirement_type": "presence",
2617
                    "groups": {
2618
                        "False": {
2619
                            "expected_value": false,
2620
                            "trial_ids": [
2621
                                "NCT00001748"
2622
                            ],
2623
                            "truth_value": "unknown"
2624
                        }
2625
                    }
2626
                }
2627
            }
2628
        },
2629
        "transplantation": {
2630
            "criterion": "transplantation",
2631
            "requirements": {
2632
                "preclusion": {
2633
                    "requirement_type": "preclusion",
2634
                    "groups": {
2635
                        "False": {
2636
                            "expected_value": false,
2637
                            "trial_ids": [
2638
                                "NCT00001748"
2639
                            ],
2640
                            "truth_value": "unknown"
2641
                        }
2642
                    }
2643
                }
2644
            }
2645
        },
2646
        "dlco": {
2647
            "criterion": "dlco",
2648
            "requirements": {
2649
                "value": {
2650
                    "requirement_type": "value",
2651
                    "groups": {
2652
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=65 unit='% predicted'": {
2653
                            "expected_value": {
2654
                                "operator": ">",
2655
                                "value": 65,
2656
                                "unit": "% predicted"
2657
                            },
2658
                            "trial_ids": [
2659
                                "NCT00001748"
2660
                            ],
2661
                            "truth_value": "unknown"
2662
                        }
2663
                    }
2664
                },
2665
                "predicted percentage": {
2666
                    "requirement_type": "predicted percentage",
2667
                    "groups": {
2668
                        "operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=65 unit='%'": {
2669
                            "expected_value": {
2670
                                "operator": ">=",
2671
                                "value": 65,
2672
                                "unit": "%"
2673
                            },
2674
                            "trial_ids": [
2675
                                "NCT00001748"
2676
                            ],
2677
                            "truth_value": "unknown"
2678
                        }
2679
                    }
2680
                }
2681
            }
2682
        },
2683
        "left ventricular ejection fraction": {
2684
            "criterion": "left ventricular ejection fraction",
2685
            "requirements": {
2686
                "value": {
2687
                    "requirement_type": "value",
2688
                    "groups": {
2689
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=40 unit='%'": {
2690
                            "expected_value": {
2691
                                "operator": ">",
2692
                                "value": 40,
2693
                                "unit": "%"
2694
                            },
2695
                            "trial_ids": [
2696
                                "NCT00001748"
2697
                            ],
2698
                            "truth_value": "unknown"
2699
                        },
2700
                        "operator=<LLMOperator.LESS_THAN: '<'> value=40 unit='%'": {
2701
                            "expected_value": {
2702
                                "operator": "<",
2703
                                "value": 40,
2704
                                "unit": "%"
2705
                            },
2706
                            "trial_ids": [
2707
                                "NCT00001748"
2708
                            ],
2709
                            "truth_value": "unknown"
2710
                        }
2711
                    }
2712
                }
2713
            }
2714
        },
2715
        "ecog performance status": {
2716
            "criterion": "ecog performance status",
2717
            "requirements": {
2718
                "value": {
2719
                    "requirement_type": "value",
2720
                    "groups": {
2721
                        "['0', '1']": {
2722
                            "expected_value": [
2723
                                "0",
2724
                                "1"
2725
                            ],
2726
                            "trial_ids": [
2727
                                "NCT00001748"
2728
                            ],
2729
                            "truth_value": "unknown"
2730
                        }
2731
                    }
2732
                },
2733
                "severity": {
2734
                    "requirement_type": "severity",
2735
                    "groups": {
2736
                        "operator=<LLMOperator.LESS_THAN: '<'> value=2 unit='N/A'": {
2737
                            "expected_value": {
2738
                                "operator": "<",
2739
                                "value": 2,
2740
                                "unit": "N/A"
2741
                            },
2742
                            "trial_ids": [
2743
                                "NCT00001748"
2744
                            ],
2745
                            "truth_value": "unknown"
2746
                        }
2747
                    }
2748
                }
2749
            }
2750
        },
2751
        "informed consent from parents": {
2752
            "criterion": "informed consent from parents",
2753
            "requirements": {
2754
                "presence": {
2755
                    "requirement_type": "presence",
2756
                    "groups": {
2757
                        "True": {
2758
                            "expected_value": true,
2759
                            "trial_ids": [
2760
                                "NCT00001748"
2761
                            ],
2762
                            "truth_value": "unknown"
2763
                        }
2764
                    }
2765
                }
2766
            }
2767
        },
2768
        "gender and reproductive status": {
2769
            "criterion": "gender and reproductive status",
2770
            "requirements": {
2771
                "gender": {
2772
                    "requirement_type": "gender",
2773
                    "groups": {
2774
                        "female": {
2775
                            "expected_value": "female",
2776
                            "trial_ids": [
2777
                                "NCT00001748"
2778
                            ],
2779
                            "truth_value": "unknown"
2780
                        }
2781
                    }
2782
                },
2783
                "reproductive status": {
2784
                    "requirement_type": "reproductive status",
2785
                    "groups": {
2786
                        "childbearing age": {
2787
                            "expected_value": "childbearing age",
2788
                            "trial_ids": [
2789
                                "NCT00001748"
2790
                            ],
2791
                            "truth_value": "unknown"
2792
                        }
2793
                    }
2794
                }
2795
            }
2796
        },
2797
        "pregnancy test result": {
2798
            "criterion": "pregnancy test result",
2799
            "requirements": {
2800
                "result": {
2801
                    "requirement_type": "result",
2802
                    "groups": {
2803
                        "negative": {
2804
                            "expected_value": "negative",
2805
                            "trial_ids": [
2806
                                "NCT00001748"
2807
                            ],
2808
                            "truth_value": "unknown"
2809
                        }
2810
                    }
2811
                }
2812
            }
2813
        },
2814
        "donor": {
2815
            "criterion": "donor",
2816
            "requirements": {
2817
                "presence": {
2818
                    "requirement_type": "presence",
2819
                    "groups": {
2820
                        "True": {
2821
                            "expected_value": true,
2822
                            "trial_ids": [
2823
                                "NCT00001748"
2824
                            ],
2825
                            "truth_value": "unknown"
2826
                        }
2827
                    }
2828
                }
2829
            }
2830
        },
2831
        "hla match with family donor": {
2832
            "criterion": "hla match with family donor",
2833
            "requirements": {
2834
                "match level": {
2835
                    "requirement_type": "match level",
2836
                    "groups": {
2837
                        "comparisons=[LLMNumericalComparison(operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='>, value=3, unit='matches'), LLMNumericalComparison(operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='>, value=5, unit='matches')]": {
2838
                            "expected_value": {
2839
                                "comparisons": [
2840
                                    {
2841
                                        "operator": ">=",
2842
                                        "value": 3,
2843
                                        "unit": "matches"
2844
                                    },
2845
                                    {
2846
                                        "operator": "<=",
2847
                                        "value": 5,
2848
                                        "unit": "matches"
2849
                                    }
2850
                                ]
2851
                            },
2852
                            "trial_ids": [
2853
                                "NCT00001748"
2854
                            ],
2855
                            "truth_value": "unknown"
2856
                        }
2857
                    }
2858
                }
2859
            }
2860
        },
2861
        "g-csf administration": {
2862
            "criterion": "g-csf administration",
2863
            "requirements": {
2864
                "fitness": {
2865
                    "requirement_type": "fitness",
2866
                    "groups": {
2867
                        "True": {
2868
                            "expected_value": true,
2869
                            "trial_ids": [
2870
                                "NCT00001748"
2871
                            ],
2872
                            "truth_value": "unknown"
2873
                        }
2874
                    }
2875
                }
2876
            }
2877
        },
2878
        "peripheral blood stem cell donation": {
2879
            "criterion": "peripheral blood stem cell donation",
2880
            "requirements": {
2881
                "fitness": {
2882
                    "requirement_type": "fitness",
2883
                    "groups": {
2884
                        "True": {
2885
                            "expected_value": true,
2886
                            "trial_ids": [
2887
                                "NCT00001748"
2888
                            ],
2889
                            "truth_value": "unknown"
2890
                        }
2891
                    }
2892
                }
2893
            }
2894
        },
2895
        "blood count": {
2896
            "criterion": "blood count",
2897
            "requirements": {
2898
                "status": {
2899
                    "requirement_type": "status",
2900
                    "groups": {
2901
                        "normal": {
2902
                            "expected_value": "normal",
2903
                            "trial_ids": [
2904
                                "NCT00001748"
2905
                            ],
2906
                            "truth_value": "unknown"
2907
                        }
2908
                    }
2909
                }
2910
            }
2911
        },
2912
        "history of stroke": {
2913
            "criterion": "history of stroke",
2914
            "requirements": {
2915
                "presence": {
2916
                    "requirement_type": "presence",
2917
                    "groups": {
2918
                        "False": {
2919
                            "expected_value": false,
2920
                            "trial_ids": [
2921
                                "NCT00001748"
2922
                            ],
2923
                            "truth_value": "unknown"
2924
                        }
2925
                    }
2926
                }
2927
            }
2928
        },
2929
        "pregnancy status": {
2930
            "criterion": "pregnancy status",
2931
            "requirements": {
2932
                "status": {
2933
                    "requirement_type": "status",
2934
                    "groups": {
2935
                        "False": {
2936
                            "expected_value": false,
2937
                            "trial_ids": [
2938
                                "NCT00001748"
2939
                            ],
2940
                            "truth_value": "unknown"
2941
                        }
2942
                    }
2943
                }
2944
            }
2945
        },
2946
        "nursing status": {
2947
            "criterion": "nursing status",
2948
            "requirements": {
2949
                "status": {
2950
                    "requirement_type": "status",
2951
                    "groups": {
2952
                        "False": {
2953
                            "expected_value": false,
2954
                            "trial_ids": [
2955
                                "NCT00001748"
2956
                            ],
2957
                            "truth_value": "unknown"
2958
                        }
2959
                    }
2960
                }
2961
            }
2962
        },
2963
        "psychiatric illness": {
2964
            "criterion": "psychiatric illness",
2965
            "requirements": {
2966
                "severity": {
2967
                    "requirement_type": "severity",
2968
                    "groups": {
2969
                        "not severe": {
2970
                            "expected_value": "not severe",
2971
                            "trial_ids": [
2972
                                "NCT00001748"
2973
                            ],
2974
                            "truth_value": "unknown"
2975
                        }
2976
                    }
2977
                }
2978
            }
2979
        },
2980
        "psychiatric illness in donor": {
2981
            "criterion": "psychiatric illness in donor",
2982
            "requirements": {
2983
                "severity": {
2984
                    "requirement_type": "severity",
2985
                    "groups": {
2986
                        "not severe": {
2987
                            "expected_value": "not severe",
2988
                            "trial_ids": [
2989
                                "NCT00001748"
2990
                            ],
2991
                            "truth_value": "unknown"
2992
                        }
2993
                    }
2994
                }
2995
            }
2996
        },
2997
        "mental deficiency": {
2998
            "criterion": "mental deficiency",
2999
            "requirements": {
3000
                "severity": {
3001
                    "requirement_type": "severity",
3002
                    "groups": {
3003
                        "sufficiently severe to make compliance with the BMT treatment unlikely": {
3004
                            "expected_value": "sufficiently severe to make compliance with the BMT treatment unlikely",
3005
                            "trial_ids": [
3006
                                "NCT00001748"
3007
                            ],
3008
                            "truth_value": "unknown"
3009
                        },
3010
                        "making informed consent impossible": {
3011
                            "expected_value": "making informed consent impossible",
3012
                            "trial_ids": [
3013
                                "NCT00001748"
3014
                            ],
3015
                            "truth_value": "unknown"
3016
                        }
3017
                    }
3018
                }
3019
            }
3020
        },
3021
        "major anticipated illness": {
3022
            "criterion": "major anticipated illness",
3023
            "requirements": {
3024
                "presence": {
3025
                    "requirement_type": "presence",
3026
                    "groups": {
3027
                        "False": {
3028
                            "expected_value": false,
3029
                            "trial_ids": [
3030
                                "NCT00001748"
3031
                            ],
3032
                            "truth_value": "unknown"
3033
                        }
3034
                    }
3035
                }
3036
            }
3037
        },
3038
        "organ failure incompatible with survival from bmt": {
3039
            "criterion": "organ failure incompatible with survival from bmt",
3040
            "requirements": {
3041
                "presence": {
3042
                    "requirement_type": "presence",
3043
                    "groups": {
3044
                        "False": {
3045
                            "expected_value": false,
3046
                            "trial_ids": [
3047
                                "NCT00001748"
3048
                            ],
3049
                            "truth_value": "unknown"
3050
                        }
3051
                    }
3052
                }
3053
            }
3054
        },
3055
        "serum creatinine": {
3056
            "criterion": "serum creatinine",
3057
            "requirements": {
3058
                "level": {
3059
                    "requirement_type": "level",
3060
                    "groups": {
3061
                        "operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=3 unit='mg/dl'": {
3062
                            "expected_value": {
3063
                                "operator": "<=",
3064
                                "value": 3,
3065
                                "unit": "mg/dl"
3066
                            },
3067
                            "trial_ids": [
3068
                                "NCT00001748"
3069
                            ],
3070
                            "truth_value": "unknown"
3071
                        }
3072
                    }
3073
                }
3074
            }
3075
        },
3076
        "serum bilirubin": {
3077
            "criterion": "serum bilirubin",
3078
            "requirements": {
3079
                "level": {
3080
                    "requirement_type": "level",
3081
                    "groups": {
3082
                        "operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=4 unit='mg/dl'": {
3083
                            "expected_value": {
3084
                                "operator": "<=",
3085
                                "value": 4,
3086
                                "unit": "mg/dl"
3087
                            },
3088
                            "trial_ids": [
3089
                                "NCT00001748"
3090
                            ],
3091
                            "truth_value": "unknown"
3092
                        }
3093
                    }
3094
                }
3095
            }
3096
        },
3097
        "transaminases": {
3098
            "criterion": "transaminases",
3099
            "requirements": {
3100
                "level": {
3101
                    "requirement_type": "level",
3102
                    "groups": {
3103
                        "operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=3 unit='times the upper limit of normal'": {
3104
                            "expected_value": {
3105
                                "operator": "<=",
3106
                                "value": 3,
3107
                                "unit": "times the upper limit of normal"
3108
                            },
3109
                            "trial_ids": [
3110
                                "NCT00001748"
3111
                            ],
3112
                            "truth_value": "unknown"
3113
                        }
3114
                    }
3115
                }
3116
            }
3117
        },
3118
        "history of other malignancies": {
3119
            "criterion": "history of other malignancies",
3120
            "requirements": {
3121
                "presence": {
3122
                    "requirement_type": "presence",
3123
                    "groups": {
3124
                        "False": {
3125
                            "expected_value": false,
3126
                            "trial_ids": [
3127
                                "NCT00001748"
3128
                            ],
3129
                            "truth_value": "unknown"
3130
                        }
3131
                    }
3132
                }
3133
            }
3134
        },
3135
        "basal cell or squamous carcinoma of the skin": {
3136
            "criterion": "basal cell or squamous carcinoma of the skin",
3137
            "requirements": {
3138
                "presence": {
3139
                    "requirement_type": "presence",
3140
                    "groups": {
3141
                        "True": {
3142
                            "expected_value": true,
3143
                            "trial_ids": [
3144
                                "NCT00001748"
3145
                            ],
3146
                            "truth_value": "unknown"
3147
                        }
3148
                    }
3149
                }
3150
            }
3151
        },
3152
        "positive pap smear": {
3153
            "criterion": "positive pap smear",
3154
            "requirements": {
3155
                "presence": {
3156
                    "requirement_type": "presence",
3157
                    "groups": {
3158
                        "True": {
3159
                            "expected_value": true,
3160
                            "trial_ids": [
3161
                                "NCT00001748"
3162
                            ],
3163
                            "truth_value": "unknown"
3164
                        }
3165
                    }
3166
                }
3167
            }
3168
        },
3169
        "negative follow up after positive pap smear": {
3170
            "criterion": "negative follow up after positive pap smear",
3171
            "requirements": {
3172
                "presence": {
3173
                    "requirement_type": "presence",
3174
                    "groups": {
3175
                        "True": {
3176
                            "expected_value": true,
3177
                            "trial_ids": [
3178
                                "NCT00001748"
3179
                            ],
3180
                            "truth_value": "unknown"
3181
                        }
3182
                    }
3183
                }
3184
            }
3185
        },
3186
        "fitness to receive g-csf": {
3187
            "criterion": "fitness to receive g-csf",
3188
            "requirements": {
3189
                "fitness": {
3190
                    "requirement_type": "fitness",
3191
                    "groups": {
3192
                        "True": {
3193
                            "expected_value": true,
3194
                            "trial_ids": [
3195
                                "NCT00001748"
3196
                            ],
3197
                            "truth_value": "unknown"
3198
                        }
3199
                    }
3200
                }
3201
            }
3202
        },
3203
        "fitness to undergo apheresis": {
3204
            "criterion": "fitness to undergo apheresis",
3205
            "requirements": {
3206
                "fitness": {
3207
                    "requirement_type": "fitness",
3208
                    "groups": {
3209
                        "True": {
3210
                            "expected_value": true,
3211
                            "trial_ids": [
3212
                                "NCT00001748"
3213
                            ],
3214
                            "truth_value": "unknown"
3215
                        }
3216
                    }
3217
                }
3218
            }
3219
        },
3220
        "cd34+ cell mobilization": {
3221
            "criterion": "cd34+ cell mobilization",
3222
            "requirements": {
3223
                "adequacy": {
3224
                    "requirement_type": "adequacy",
3225
                    "groups": {
3226
                        "True": {
3227
                            "expected_value": true,
3228
                            "trial_ids": [
3229
                                "NCT00001748"
3230
                            ],
3231
                            "truth_value": "unknown"
3232
                        }
3233
                    }
3234
                }
3235
            }
3236
        },
3237
        "g-csf cycles": {
3238
            "criterion": "g-csf cycles",
3239
            "requirements": {
3240
                "quantity": {
3241
                    "requirement_type": "quantity",
3242
                    "groups": {
3243
                        "operator=<LLMOperator.EQUAL_TO: '='> value=2 unit='cycles'": {
3244
                            "expected_value": {
3245
                                "operator": "=",
3246
                                "value": 2,
3247
                                "unit": "cycles"
3248
                            },
3249
                            "trial_ids": [
3250
                                "NCT00001748"
3251
                            ],
3252
                            "truth_value": "unknown"
3253
                        }
3254
                    }
3255
                }
3256
            }
3257
        },
3258
        "kaposi's sarcoma": {
3259
            "criterion": "kaposi's sarcoma",
3260
            "requirements": {
3261
                "diagnosis": {
3262
                    "requirement_type": "diagnosis",
3263
                    "groups": {
3264
                        "biopsy-proven": {
3265
                            "expected_value": "biopsy-proven",
3266
                            "trial_ids": [
3267
                                "NCT00002262"
3268
                            ],
3269
                            "truth_value": "unknown"
3270
                        }
3271
                    }
3272
                }
3273
            }
3274
        },
3275
        "cutaneous lesions": {
3276
            "criterion": "cutaneous lesions",
3277
            "requirements": {
3278
                "quantity": {
3279
                    "requirement_type": "quantity",
3280
                    "groups": {
3281
                        "multiple": {
3282
                            "expected_value": "multiple",
3283
                            "trial_ids": [
3284
                                "NCT00002262"
3285
                            ],
3286
                            "truth_value": "unknown"
3287
                        }
3288
                    }
3289
                }
3290
            }
3291
        },
3292
        "life expectancy": {
3293
            "criterion": "life expectancy",
3294
            "requirements": {
3295
                "duration": {
3296
                    "requirement_type": "duration",
3297
                    "groups": {
3298
                        "operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=3 unit='months'": {
3299
                            "expected_value": {
3300
                                "operator": ">=",
3301
                                "value": 3,
3302
                                "unit": "months"
3303
                            },
3304
                            "trial_ids": [
3305
                                "NCT00002262"
3306
                            ],
3307
                            "truth_value": "unknown"
3308
                        }
3309
                    }
3310
                },
3311
                "minimum duration": {
3312
                    "requirement_type": "minimum duration",
3313
                    "groups": {
3314
                        "operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=8 unit='weeks'": {
3315
                            "expected_value": {
3316
                                "operator": ">=",
3317
                                "value": 8,
3318
                                "unit": "weeks"
3319
                            },
3320
                            "trial_ids": [
3321
                                "NCT00002620"
3322
                            ],
3323
                            "truth_value": "unknown"
3324
                        }
3325
                    }
3326
                }
3327
            }
3328
        },
3329
        "co-existing condition": {
3330
            "criterion": "co-existing condition",
3331
            "requirements": {
3332
                "presence": {
3333
                    "requirement_type": "presence",
3334
                    "groups": {
3335
                        "True": {
3336
                            "expected_value": true,
3337
                            "trial_ids": [
3338
                                "NCT00002262"
3339
                            ],
3340
                            "truth_value": "unknown"
3341
                        }
3342
                    }
3343
                }
3344
            }
3345
        },
3346
        "cardiac disease": {
3347
            "criterion": "cardiac disease",
3348
            "requirements": {
3349
                "severity": {
3350
                    "requirement_type": "severity",
3351
                    "groups": {
3352
                        "clinically significant": {
3353
                            "expected_value": "clinically significant",
3354
                            "trial_ids": [
3355
                                "NCT00002262"
3356
                            ],
3357
                            "truth_value": "unknown"
3358
                        }
3359
                    }
3360
                }
3361
            }
3362
        },
3363
        "hemorrhagic diathesis": {
3364
            "criterion": "hemorrhagic diathesis",
3365
            "requirements": {
3366
                "presence": {
3367
                    "requirement_type": "presence",
3368
                    "groups": {
3369
                        "True": {
3370
                            "expected_value": true,
3371
                            "trial_ids": [
3372
                                "NCT00002262"
3373
                            ],
3374
                            "truth_value": "unknown"
3375
                        }
3376
                    }
3377
                }
3378
            }
3379
        },
3380
        "bleeding disorder": {
3381
            "criterion": "bleeding disorder",
3382
            "requirements": {
3383
                "activity": {
3384
                    "requirement_type": "activity",
3385
                    "groups": {
3386
                        "True": {
3387
                            "expected_value": true,
3388
                            "trial_ids": [
3389
                                "NCT00002262"
3390
                            ],
3391
                            "truth_value": "unknown"
3392
                        }
3393
                    }
3394
                }
3395
            }
3396
        },
3397
        "vascular disease": {
3398
            "criterion": "vascular disease",
3399
            "requirements": {
3400
                "presence": {
3401
                    "requirement_type": "presence",
3402
                    "groups": {
3403
                        "True": {
3404
                            "expected_value": true,
3405
                            "trial_ids": [
3406
                                "NCT00002262"
3407
                            ],
3408
                            "truth_value": "unknown"
3409
                        }
3410
                    }
3411
                },
3412
                "clinical appearance": {
3413
                    "requirement_type": "clinical appearance",
3414
                    "groups": {
3415
                        "True": {
3416
                            "expected_value": true,
3417
                            "trial_ids": [
3418
                                "NCT00002262"
3419
                            ],
3420
                            "truth_value": "unknown"
3421
                        }
3422
                    }
3423
                }
3424
            }
3425
        },
3426
        "lipoprotein disorders": {
3427
            "criterion": "lipoprotein disorders",
3428
            "requirements": {
3429
                "presence": {
3430
                    "requirement_type": "presence",
3431
                    "groups": {
3432
                        "True": {
3433
                            "expected_value": true,
3434
                            "trial_ids": [
3435
                                "NCT00002262"
3436
                            ],
3437
                            "truth_value": "unknown"
3438
                        }
3439
                    }
3440
                }
3441
            }
3442
        },
3443
        "seizure disorder": {
3444
            "criterion": "seizure disorder",
3445
            "requirements": {
3446
                "history": {
3447
                    "requirement_type": "history",
3448
                    "groups": {
3449
                        "True": {
3450
                            "expected_value": true,
3451
                            "trial_ids": [
3452
                                "NCT00002262"
3453
                            ],
3454
                            "truth_value": "unknown"
3455
                        }
3456
                    }
3457
                }
3458
            }
3459
        },
3460
        "cns metastasis": {
3461
            "criterion": "cns metastasis",
3462
            "requirements": {
3463
                "presence": {
3464
                    "requirement_type": "presence",
3465
                    "groups": {
3466
                        "True": {
3467
                            "expected_value": true,
3468
                            "trial_ids": [
3469
                                "NCT00002262"
3470
                            ],
3471
                            "truth_value": "unknown"
3472
                        }
3473
                    }
3474
                }
3475
            }
3476
        },
3477
        "additional malignancy": {
3478
            "criterion": "additional malignancy",
3479
            "requirements": {
3480
                "presence": {
3481
                    "requirement_type": "presence",
3482
                    "groups": {
3483
                        "True": {
3484
                            "expected_value": true,
3485
                            "trial_ids": [
3486
                                "NCT00002262"
3487
                            ],
3488
                            "truth_value": "unknown"
3489
                        }
3490
                    }
3491
                }
3492
            }
3493
        },
3494
        "concurrent medication": {
3495
            "criterion": "concurrent medication",
3496
            "requirements": {
3497
                "presence": {
3498
                    "requirement_type": "presence",
3499
                    "groups": {
3500
                        "True": {
3501
                            "expected_value": true,
3502
                            "trial_ids": [
3503
                                "NCT00002262"
3504
                            ],
3505
                            "truth_value": "unknown"
3506
                        }
3507
                    }
3508
                }
3509
            }
3510
        },
3511
        "cardiac agents": {
3512
            "criterion": "cardiac agents",
3513
            "requirements": {
3514
                "presence": {
3515
                    "requirement_type": "presence",
3516
                    "groups": {
3517
                        "True": {
3518
                            "expected_value": true,
3519
                            "trial_ids": [
3520
                                "NCT00002262"
3521
                            ],
3522
                            "truth_value": "unknown"
3523
                        }
3524
                    }
3525
                }
3526
            }
3527
        },
3528
        "anticoagulant use": {
3529
            "criterion": "anticoagulant use",
3530
            "requirements": {
3531
                "presence": {
3532
                    "requirement_type": "presence",
3533
                    "groups": {
3534
                        "True": {
3535
                            "expected_value": true,
3536
                            "trial_ids": [
3537
                                "NCT00002262"
3538
                            ],
3539
                            "truth_value": "unknown"
3540
                        }
3541
                    }
3542
                }
3543
            }
3544
        },
3545
        "thrombolytic agents": {
3546
            "criterion": "thrombolytic agents",
3547
            "requirements": {
3548
                "presence": {
3549
                    "requirement_type": "presence",
3550
                    "groups": {
3551
                        "False": {
3552
                            "expected_value": false,
3553
                            "trial_ids": [
3554
                                "NCT00002262"
3555
                            ],
3556
                            "truth_value": "unknown"
3557
                        }
3558
                    }
3559
                }
3560
            }
3561
        },
3562
        "nonsteroidal anti-inflammatory drugs": {
3563
            "criterion": "nonsteroidal anti-inflammatory drugs",
3564
            "requirements": {
3565
                "presence": {
3566
                    "requirement_type": "presence",
3567
                    "groups": {
3568
                        "True": {
3569
                            "expected_value": true,
3570
                            "trial_ids": [
3571
                                "NCT00002262"
3572
                            ],
3573
                            "truth_value": "unknown"
3574
                        }
3575
                    }
3576
                }
3577
            }
3578
        },
3579
        "corticosteroids": {
3580
            "criterion": "corticosteroids",
3581
            "requirements": {
3582
                "presence": {
3583
                    "requirement_type": "presence",
3584
                    "groups": {
3585
                        "True": {
3586
                            "expected_value": true,
3587
                            "trial_ids": [
3588
                                "NCT00002262"
3589
                            ],
3590
                            "truth_value": "unknown"
3591
                        }
3592
                    }
3593
                }
3594
            }
3595
        },
3596
        "aspirin": {
3597
            "criterion": "aspirin",
3598
            "requirements": {
3599
                "presence": {
3600
                    "requirement_type": "presence",
3601
                    "groups": {
3602
                        "True": {
3603
                            "expected_value": true,
3604
                            "trial_ids": [
3605
                                "NCT00002262"
3606
                            ],
3607
                            "truth_value": "unknown"
3608
                        }
3609
                    }
3610
                }
3611
            }
3612
        },
3613
        "vasodilator use": {
3614
            "criterion": "vasodilator use",
3615
            "requirements": {
3616
                "presence": {
3617
                    "requirement_type": "presence",
3618
                    "groups": {
3619
                        "True": {
3620
                            "expected_value": true,
3621
                            "trial_ids": [
3622
                                "NCT00002262"
3623
                            ],
3624
                            "truth_value": "unknown"
3625
                        }
3626
                    }
3627
                }
3628
            }
3629
        },
3630
        "additional malignancies": {
3631
            "criterion": "additional malignancies",
3632
            "requirements": {
3633
                "presence": {
3634
                    "requirement_type": "presence",
3635
                    "groups": {
3636
                        "False": {
3637
                            "expected_value": false,
3638
                            "trial_ids": [
3639
                                "NCT00002262"
3640
                            ],
3641
                            "truth_value": "unknown"
3642
                        }
3643
                    }
3644
                }
3645
            }
3646
        },
3647
        "other conditions listed in patient exclusion co-existing conditions": {
3648
            "criterion": "other conditions listed in patient exclusion co-existing conditions",
3649
            "requirements": {
3650
                "presence": {
3651
                    "requirement_type": "presence",
3652
                    "groups": {
3653
                        "False": {
3654
                            "expected_value": false,
3655
                            "trial_ids": [
3656
                                "NCT00002262"
3657
                            ],
3658
                            "truth_value": "unknown"
3659
                        }
3660
                    }
3661
                }
3662
            }
3663
        },
3664
        "prior treatment": {
3665
            "criterion": "prior treatment",
3666
            "requirements": {
3667
                "presence": {
3668
                    "requirement_type": "presence",
3669
                    "groups": {
3670
                        "True": {
3671
                            "expected_value": true,
3672
                            "trial_ids": [
3673
                                "NCT00002262"
3674
                            ],
3675
                            "truth_value": "unknown"
3676
                        }
3677
                    }
3678
                }
3679
            }
3680
        },
3681
        "time since exclusion": {
3682
            "criterion": "time since exclusion",
3683
            "requirements": {
3684
                "duration": {
3685
                    "requirement_type": "duration",
3686
                    "groups": {
3687
                        "operator=<LLMOperator.LESS_THAN_OR_EQUAL_TO: '<='> value=4 unit='weeks'": {
3688
                            "expected_value": {
3689
                                "operator": "<=",
3690
                                "value": 4,
3691
                                "unit": "weeks"
3692
                            },
3693
                            "trial_ids": [
3694
                                "NCT00002262"
3695
                            ],
3696
                            "truth_value": "unknown"
3697
                        }
3698
                    }
3699
                }
3700
            }
3701
        },
3702
        "chemotherapy": {
3703
            "criterion": "chemotherapy",
3704
            "requirements": {
3705
                "presence": {
3706
                    "requirement_type": "presence",
3707
                    "groups": {
3708
                        "True": {
3709
                            "expected_value": true,
3710
                            "trial_ids": [
3711
                                "NCT00002262"
3712
                            ],
3713
                            "truth_value": "unknown"
3714
                        }
3715
                    }
3716
                },
3717
                "prior therapy": {
3718
                    "requirement_type": "prior therapy",
3719
                    "groups": {
3720
                        "False": {
3721
                            "expected_value": false,
3722
                            "trial_ids": [
3723
                                "NCT00002476"
3724
                            ],
3725
                            "truth_value": "unknown"
3726
                        }
3727
                    }
3728
                },
3729
                "prior treatment": {
3730
                    "requirement_type": "prior treatment",
3731
                    "groups": {
3732
                        "False": {
3733
                            "expected_value": false,
3734
                            "trial_ids": [
3735
                                "NCT00002631"
3736
                            ],
3737
                            "truth_value": "unknown"
3738
                        }
3739
                    }
3740
                }
3741
            }
3742
        },
3743
        "radiotherapy": {
3744
            "criterion": "radiotherapy",
3745
            "requirements": {
3746
                "presence": {
3747
                    "requirement_type": "presence",
3748
                    "groups": {
3749
                        "True": {
3750
                            "expected_value": true,
3751
                            "trial_ids": [
3752
                                "NCT00002262"
3753
                            ],
3754
                            "truth_value": "unknown"
3755
                        }
3756
                    }
3757
                },
3758
                "prior therapy": {
3759
                    "requirement_type": "prior therapy",
3760
                    "groups": {
3761
                        "False": {
3762
                            "expected_value": false,
3763
                            "trial_ids": [
3764
                                "NCT00002476"
3765
                            ],
3766
                            "truth_value": "unknown"
3767
                        }
3768
                    }
3769
                }
3770
            }
3771
        },
3772
        "immunotherapy": {
3773
            "criterion": "immunotherapy",
3774
            "requirements": {
3775
                "treatment": {
3776
                    "requirement_type": "treatment",
3777
                    "groups": {
3778
                        "True": {
3779
                            "expected_value": true,
3780
                            "trial_ids": [
3781
                                "NCT00002262"
3782
                            ],
3783
                            "truth_value": "unknown"
3784
                        }
3785
                    }
3786
                }
3787
            }
3788
        },
3789
        "squamous cell cancer of the head and neck": {
3790
            "criterion": "squamous cell cancer of the head and neck",
3791
            "requirements": {
3792
                "confirmation": {
3793
                    "requirement_type": "confirmation",
3794
                    "groups": {
3795
                        "histologically confirmed": {
3796
                            "expected_value": "histologically confirmed",
3797
                            "trial_ids": [
3798
                                "NCT00002476"
3799
                            ],
3800
                            "truth_value": "unknown"
3801
                        }
3802
                    }
3803
                }
3804
            }
3805
        },
3806
        "suitability for treatment with radiotherapy": {
3807
            "criterion": "suitability for treatment with radiotherapy",
3808
            "requirements": {
3809
                "suitability": {
3810
                    "requirement_type": "suitability",
3811
                    "groups": {
3812
                        "True": {
3813
                            "expected_value": true,
3814
                            "trial_ids": [
3815
                                "NCT00002476"
3816
                            ],
3817
                            "truth_value": "unknown"
3818
                        }
3819
                    }
3820
                }
3821
            }
3822
        },
3823
        "primary lesion stage": {
3824
            "criterion": "primary lesion stage",
3825
            "requirements": {
3826
                "stage": {
3827
                    "requirement_type": "stage",
3828
                    "groups": {
3829
                        "['T2', 'T3', 'T4']": {
3830
                            "expected_value": [
3831
                                "T2",
3832
                                "T3",
3833
                                "T4"
3834
                            ],
3835
                            "trial_ids": [
3836
                                "NCT00002476"
3837
                            ],
3838
                            "truth_value": "unknown"
3839
                        }
3840
                    }
3841
                }
3842
            }
3843
        },
3844
        "nodal involvement": {
3845
            "criterion": "nodal involvement",
3846
            "requirements": {
3847
                "stage": {
3848
                    "requirement_type": "stage",
3849
                    "groups": {
3850
                        "Any N": {
3851
                            "expected_value": "Any N",
3852
                            "trial_ids": [
3853
                                "NCT00002476"
3854
                            ],
3855
                            "truth_value": "unknown"
3856
                        }
3857
                    }
3858
                }
3859
            }
3860
        },
3861
        "distant metastasis": {
3862
            "criterion": "distant metastasis",
3863
            "requirements": {
3864
                "presence": {
3865
                    "requirement_type": "presence",
3866
                    "groups": {
3867
                        "False": {
3868
                            "expected_value": false,
3869
                            "trial_ids": [
3870
                                "NCT00002476"
3871
                            ],
3872
                            "truth_value": "unknown"
3873
                        }
3874
                    }
3875
                }
3876
            }
3877
        },
3878
        "carcinoma type": {
3879
            "criterion": "carcinoma type",
3880
            "requirements": {
3881
                "type": {
3882
                    "requirement_type": "type",
3883
                    "groups": {
3884
                        "['anaplastic carcinoma', 'verrucous carcinoma', 'transitional cell carcinoma']": {
3885
                            "expected_value": [
3886
                                "anaplastic carcinoma",
3887
                                "verrucous carcinoma",
3888
                                "transitional cell carcinoma"
3889
                            ],
3890
                            "trial_ids": [
3891
                                "NCT00002476"
3892
                            ],
3893
                            "truth_value": "unknown"
3894
                        }
3895
                    }
3896
                }
3897
            }
3898
        },
3899
        "occult primaries": {
3900
            "criterion": "occult primaries",
3901
            "requirements": {
3902
                "presence": {
3903
                    "requirement_type": "presence",
3904
                    "groups": {
3905
                        "False": {
3906
                            "expected_value": false,
3907
                            "trial_ids": [
3908
                                "NCT00002476"
3909
                            ],
3910
                            "truth_value": "unknown"
3911
                        }
3912
                    }
3913
                }
3914
            }
3915
        },
3916
        "cancer type exclusion": {
3917
            "criterion": "cancer type exclusion",
3918
            "requirements": {
3919
                "exclusion": {
3920
                    "requirement_type": "exclusion",
3921
                    "groups": {
3922
                        "['adenocarcinomas', 'lymphomas', 'melanomas']": {
3923
                            "expected_value": [
3924
                                "adenocarcinomas",
3925
                                "lymphomas",
3926
                                "melanomas"
3927
                            ],
3928
                            "trial_ids": [
3929
                                "NCT00002476"
3930
                            ],
3931
                            "truth_value": "unknown"
3932
                        }
3933
                    }
3934
                }
3935
            }
3936
        },
3937
        "synchronous head and neck tumors": {
3938
            "criterion": "synchronous head and neck tumors",
3939
            "requirements": {
3940
                "eligibility": {
3941
                    "requirement_type": "eligibility",
3942
                    "groups": {
3943
                        "True": {
3944
                            "expected_value": true,
3945
                            "trial_ids": [
3946
                                "NCT00002476"
3947
                            ],
3948
                            "truth_value": "unknown"
3949
                        }
3950
                    }
3951
                }
3952
            }
3953
        },
3954
        "surgery to neck nodes": {
3955
            "criterion": "surgery to neck nodes",
3956
            "requirements": {
3957
                "randomization": {
3958
                    "requirement_type": "randomization",
3959
                    "groups": {
3960
                        "surgery patients": {
3961
                            "expected_value": "surgery patients",
3962
                            "trial_ids": [
3963
                                "NCT00002476"
3964
                            ],
3965
                            "truth_value": "unknown"
3966
                        }
3967
                    }
3968
                }
3969
            }
3970
        },
3971
        "tumors of the oral cavity or oropharynx": {
3972
            "criterion": "tumors of the oral cavity or oropharynx",
3973
            "requirements": {
3974
                "randomization option": {
3975
                    "requirement_type": "randomization option",
3976
                    "groups": {
3977
                        "nodal irradiation vs. no further therapy": {
3978
                            "expected_value": "nodal irradiation vs. no further therapy",
3979
                            "trial_ids": [
3980
                                "NCT00002476"
3981
                            ],
3982
                            "truth_value": "unknown"
3983
                        }
3984
                    }
3985
                },
3986
                "condition": {
3987
                    "requirement_type": "condition",
3988
                    "groups": {
3989
                        "no second primary": {
3990
                            "expected_value": "no second primary",
3991
                            "trial_ids": [
3992
                                "NCT00002476"
3993
                            ],
3994
                            "truth_value": "unknown"
3995
                        }
3996
                    }
3997
                }
3998
            }
3999
        },
4000
        "fitness for protocol treatment": {
4001
            "criterion": "fitness for protocol treatment",
4002
            "requirements": {
4003
                "fitness": {
4004
                    "requirement_type": "fitness",
4005
                    "groups": {
4006
                        "True": {
4007
                            "expected_value": true,
4008
                            "trial_ids": [
4009
                                "NCT00002476"
4010
                            ],
4011
                            "truth_value": "unknown"
4012
                        }
4013
                    }
4014
                }
4015
            }
4016
        },
4017
        "willingness to receive protocol treatment": {
4018
            "criterion": "willingness to receive protocol treatment",
4019
            "requirements": {
4020
                "willingness": {
4021
                    "requirement_type": "willingness",
4022
                    "groups": {
4023
                        "True": {
4024
                            "expected_value": true,
4025
                            "trial_ids": [
4026
                                "NCT00002476"
4027
                            ],
4028
                            "truth_value": "unknown"
4029
                        }
4030
                    }
4031
                }
4032
            }
4033
        },
4034
        "prior malignancy": {
4035
            "criterion": "prior malignancy",
4036
            "requirements": {
4037
                "cured status": {
4038
                    "requirement_type": "cured status",
4039
                    "groups": {
4040
                        "True": {
4041
                            "expected_value": true,
4042
                            "trial_ids": [
4043
                                "NCT00002476"
4044
                            ],
4045
                            "truth_value": "unknown"
4046
                        }
4047
                    }
4048
                }
4049
            }
4050
        },
4051
        "biologic therapy": {
4052
            "criterion": "biologic therapy",
4053
            "requirements": {
4054
                "prior therapy": {
4055
                    "requirement_type": "prior therapy",
4056
                    "groups": {
4057
                        "False": {
4058
                            "expected_value": false,
4059
                            "trial_ids": [
4060
                                "NCT00002476"
4061
                            ],
4062
                            "truth_value": "unknown"
4063
                        }
4064
                    }
4065
                }
4066
            }
4067
        },
4068
        "endocrine therapy": {
4069
            "criterion": "endocrine therapy",
4070
            "requirements": {
4071
                "prior therapy": {
4072
                    "requirement_type": "prior therapy",
4073
                    "groups": {
4074
                        "False": {
4075
                            "expected_value": false,
4076
                            "trial_ids": [
4077
                                "NCT00002476"
4078
                            ],
4079
                            "truth_value": "unknown"
4080
                        }
4081
                    }
4082
                }
4083
            }
4084
        },
4085
        "surgery": {
4086
            "criterion": "surgery",
4087
            "requirements": {
4088
                "prior biopsy or excision": {
4089
                    "requirement_type": "prior biopsy or excision",
4090
                    "groups": {
4091
                        "True": {
4092
                            "expected_value": true,
4093
                            "trial_ids": [
4094
                                "NCT00002476"
4095
                            ],
4096
                            "truth_value": "unknown"
4097
                        }
4098
                    }
4099
                }
4100
            }
4101
        },
4102
        "surgical procedure": {
4103
            "criterion": "surgical procedure",
4104
            "requirements": {
4105
                "type": {
4106
                    "requirement_type": "type",
4107
                    "groups": {
4108
                        "['standard maximum resection', 'stereotactic biopsy']": {
4109
                            "expected_value": [
4110
                                "standard maximum resection",
4111
                                "stereotactic biopsy"
4112
                            ],
4113
                            "trial_ids": [
4114
                                "NCT00002620"
4115
                            ],
4116
                            "truth_value": "unknown"
4117
                        }
4118
                    }
4119
                },
4120
                "timing": {
4121
                    "requirement_type": "timing",
4122
                    "groups": {
4123
                        "within 4 weeks prior to therapy": {
4124
                            "expected_value": "within 4 weeks prior to therapy",
4125
                            "trial_ids": [
4126
                                "NCT00002620"
4127
                            ],
4128
                            "truth_value": "unknown"
4129
                        }
4130
                    }
4131
                }
4132
            }
4133
        },
4134
        "white blood cell count": {
4135
            "criterion": "white blood cell count",
4136
            "requirements": {
4137
                "minimum count": {
4138
                    "requirement_type": "minimum count",
4139
                    "groups": {
4140
                        "operator=<LLMOperator.GREATER_THAN: '>'> value=4000 unit='N/A'": {
4141
                            "expected_value": {
4142
                                "operator": ">",
4143
                                "value": 4000,
4144
                                "unit": "N/A"
4145
                            },
4146
                            "trial_ids": [
4147
                                "NCT00002620"
4148
                            ],
4149
                            "truth_value": "unknown"
4150
                        }
4151
                    }
4152
                }
4153
            }
4154
        },
4155
        "bilirubin level": {
4156
            "criterion": "bilirubin level",
4157
            "requirements": {
4158
                "maximum level": {
4159
                    "requirement_type": "maximum level",
4160
                    "groups": {
4161
                        "operator=<LLMOperator.LESS_THAN: '<'> value=2 unit='mg/dl'": {
4162
                            "expected_value": {
4163
                                "operator": "<",
4164
                                "value": 2,
4165
                                "unit": "mg/dl"
4166
                            },
4167
                            "trial_ids": [
4168
                                "NCT00002620"
4169
                            ],
4170
                            "truth_value": "unknown"
4171
                        }
4172
                    }
4173
                }
4174
            }
4175
        },
4176
        "creatinine level": {
4177
            "criterion": "creatinine level",
4178
            "requirements": {
4179
                "maximum level": {
4180
                    "requirement_type": "maximum level",
4181
                    "groups": {
4182
                        "operator=<LLMOperator.LESS_THAN: '<'> value=1.5 unit='mg/dl'": {
4183
                            "expected_value": {
4184
                                "operator": "<",
4185
                                "value": 1.5,
4186
                                "unit": "mg/dl"
4187
                            },
4188
                            "trial_ids": [
4189
                                "NCT00002620"
4190
                            ],
4191
                            "truth_value": "unknown"
4192
                        }
4193
                    }
4194
                }
4195
            }
4196
        },
4197
        "blood urea nitrogen level": {
4198
            "criterion": "blood urea nitrogen level",
4199
            "requirements": {
4200
                "maximum level": {
4201
                    "requirement_type": "maximum level",
4202
                    "groups": {
4203
                        "operator=<LLMOperator.LESS_THAN: '<'> value=40 unit='mg/dl'": {
4204
                            "expected_value": {
4205
                                "operator": "<",
4206
                                "value": 40,
4207
                                "unit": "mg/dl"
4208
                            },
4209
                            "trial_ids": [
4210
                                "NCT00002620"
4211
                            ],
4212
                            "truth_value": "unknown"
4213
                        }
4214
                    }
4215
                }
4216
            }
4217
        },
4218
        "major medical illness": {
4219
            "criterion": "major medical illness",
4220
            "requirements": {
4221
                "presence": {
4222
                    "requirement_type": "presence",
4223
                    "groups": {
4224
                        "False": {
4225
                            "expected_value": false,
4226
                            "trial_ids": [
4227
                                "NCT00002620"
4228
                            ],
4229
                            "truth_value": "unknown"
4230
                        }
4231
                    }
4232
                }
4233
            }
4234
        },
4235
        "anticancer drugs": {
4236
            "criterion": "anticancer drugs",
4237
            "requirements": {
4238
                "usage": {
4239
                    "requirement_type": "usage",
4240
                    "groups": {
4241
                        "False": {
4242
                            "expected_value": false,
4243
                            "trial_ids": [
4244
                                "NCT00002620"
4245
                            ],
4246
                            "truth_value": "unknown"
4247
                        }
4248
                    }
4249
                }
4250
            }
4251
        },
4252
        "steroids": {
4253
            "criterion": "steroids",
4254
            "requirements": {
4255
                "usage": {
4256
                    "requirement_type": "usage",
4257
                    "groups": {
4258
                        "False": {
4259
                            "expected_value": false,
4260
                            "trial_ids": [
4261
                                "NCT00002620"
4262
                            ],
4263
                            "truth_value": "unknown"
4264
                        }
4265
                    }
4266
                }
4267
            }
4268
        },
4269
        "primary squamous cell or adenocarcinoma of the esophagus": {
4270
            "criterion": "primary squamous cell or adenocarcinoma of the esophagus",
4271
            "requirements": {
4272
                "presence": {
4273
                    "requirement_type": "presence",
4274
                    "groups": {
4275
                        "True": {
4276
                            "expected_value": true,
4277
                            "trial_ids": [
4278
                                "NCT00002631"
4279
                            ],
4280
                            "truth_value": "unknown"
4281
                        }
4282
                    }
4283
                }
4284
            }
4285
        },
4286
        "clinical stage": {
4287
            "criterion": "clinical stage",
4288
            "requirements": {
4289
                "stage": {
4290
                    "requirement_type": "stage",
4291
                    "groups": {
4292
                        "['T1', 'T2', 'T3', 'T4']": {
4293
                            "expected_value": [
4294
                                "T1",
4295
                                "T2",
4296
                                "T3",
4297
                                "T4"
4298
                            ],
4299
                            "trial_ids": [
4300
                                "NCT00002631"
4301
                            ],
4302
                            "truth_value": "unknown"
4303
                        }
4304
                    }
4305
                },
4306
                "node involvement": {
4307
                    "requirement_type": "node involvement",
4308
                    "groups": {
4309
                        "Nx": {
4310
                            "expected_value": "Nx",
4311
                            "trial_ids": [
4312
                                "NCT00002631"
4313
                            ],
4314
                            "truth_value": "unknown"
4315
                        }
4316
                    }
4317
                },
4318
                "metastasis": {
4319
                    "requirement_type": "metastasis",
4320
                    "groups": {
4321
                        "M0": {
4322
                            "expected_value": "M0",
4323
                            "trial_ids": [
4324
                                "NCT00002631"
4325
                            ],
4326
                            "truth_value": "unknown"
4327
                        }
4328
                    }
4329
                }
4330
            }
4331
        },
4332
        "disease location": {
4333
            "criterion": "disease location",
4334
            "requirements": {
4335
                "location": {
4336
                    "requirement_type": "location",
4337
                    "groups": {
4338
                        "esophagus and periesophageal soft tissue": {
4339
                            "expected_value": "esophagus and periesophageal soft tissue",
4340
                            "trial_ids": [
4341
                                "NCT00002631"
4342
                            ],
4343
                            "truth_value": "unknown"
4344
                        }
4345
                    }
4346
                }
4347
            }
4348
        },
4349
        "tumor extension": {
4350
            "criterion": "tumor extension",
4351
            "requirements": {
4352
                "distance from stomach": {
4353
                    "requirement_type": "distance from stomach",
4354
                    "groups": {
4355
                        "operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=2 unit='cm'": {
4356
                            "expected_value": {
4357
                                "operator": ">=",
4358
                                "value": 2,
4359
                                "unit": "cm"
4360
                            },
4361
                            "trial_ids": [
4362
                                "NCT00002631"
4363
                            ],
4364
                            "truth_value": "unknown"
4365
                        }
4366
                    }
4367
                }
4368
            }
4369
        },
4370
        "invasion of the tracheal-bronchial tree": {
4371
            "criterion": "invasion of the tracheal-bronchial tree",
4372
            "requirements": {
4373
                "presence": {
4374
                    "requirement_type": "presence",
4375
                    "groups": {
4376
                        "False": {
4377
                            "expected_value": false,
4378
                            "trial_ids": [
4379
                                "NCT00002631"
4380
                            ],
4381
                            "truth_value": "unknown"
4382
                        }
4383
                    }
4384
                }
4385
            }
4386
        },
4387
        "tracheal-esophageal (te) fistula": {
4388
            "criterion": "tracheal-esophageal (te) fistula",
4389
            "requirements": {
4390
                "presence": {
4391
                    "requirement_type": "presence",
4392
                    "groups": {
4393
                        "False": {
4394
                            "expected_value": false,
4395
                            "trial_ids": [
4396
                                "NCT00002631"
4397
                            ],
4398
                            "truth_value": "unknown"
4399
                        }
4400
                    }
4401
                }
4402
            }
4403
        },
4404
        "bronchoscopy requirement": {
4405
            "criterion": "bronchoscopy requirement",
4406
            "requirements": {
4407
                "lesion distance from incisors": {
4408
                    "requirement_type": "lesion distance from incisors",
4409
                    "groups": {
4410
                        "operator=<LLMOperator.LESS_THAN: '<'> value=30 unit='cm'": {
4411
                            "expected_value": {
4412
                                "operator": "<",
4413
                                "value": 30,
4414
                                "unit": "cm"
4415
                            },
4416
                            "trial_ids": [
4417
                                "NCT00002631"
4418
                            ],
4419
                            "truth_value": "unknown"
4420
                        }
4421
                    }
4422
                }
4423
            }
4424
        },
4425
        "liver biopsy": {
4426
            "criterion": "liver biopsy",
4427
            "requirements": {
4428
                "result": {
4429
                    "requirement_type": "result",
4430
                    "groups": {
4431
                        "negative": {
4432
                            "expected_value": "negative",
4433
                            "trial_ids": [
4434
                                "NCT00002631"
4435
                            ],
4436
                            "truth_value": "unknown"
4437
                        }
4438
                    }
4439
                }
4440
            }
4441
        },
4442
        "retroperitoneal or celiac nodes biopsy": {
4443
            "criterion": "retroperitoneal or celiac nodes biopsy",
4444
            "requirements": {
4445
                "result": {
4446
                    "requirement_type": "result",
4447
                    "groups": {
4448
                        "negative": {
4449
                            "expected_value": "negative",
4450
                            "trial_ids": [
4451
                                "NCT00002631"
4452
                            ],
4453
                            "truth_value": "unknown"
4454
                        }
4455
                    }
4456
                },
4457
                "node size": {
4458
                    "requirement_type": "node size",
4459
                    "groups": {
4460
                        "operator=<LLMOperator.GREATER_THAN_OR_EQUAL_TO: '>='> value=1.5 unit='cm'": {
4461
                            "expected_value": {
4462
                                "operator": ">=",
4463
                                "value": 1.5,
4464
                                "unit": "cm"
4465
                            },
4466
                            "trial_ids": [
4467
                                "NCT00002631"
4468
                            ],
4469
                            "truth_value": "unknown"
4470
                        }
4471
                    }
4472
                }
4473
            }
4474
        },
4475
        "supraclavicular nodes biopsy": {
4476
            "criterion": "supraclavicular nodes biopsy",
4477
            "requirements": {
4478
                "result": {
4479
                    "requirement_type": "result",
4480
                    "groups": {
4481
                        "negative": {
4482
                            "expected_value": "negative",
4483
                            "trial_ids": [
4484
                                "NCT00002631"
4485
                            ],
4486
                            "truth_value": "unknown"
4487
                        }
4488
                    }
4489
                }
4490
            }
4491
        },
4492
        "recurrent disease": {
4493
            "criterion": "recurrent disease",
4494
            "requirements": {
4495
                "presence": {
4496
                    "requirement_type": "presence",
4497
                    "groups": {
4498
                        "False": {
4499
                            "expected_value": false,
4500
                            "trial_ids": [
4501
                                "NCT00002631"
4502
                            ],
4503
                            "truth_value": "unknown"
4504
                        }
4505
                    }
4506
                }
4507
            }
4508
        },
4509
        "multiple carcinomas of the esophagus": {
4510
            "criterion": "multiple carcinomas of the esophagus",
4511
            "requirements": {
4512
                "presence": {
4513
                    "requirement_type": "presence",
4514
                    "groups": {
4515
                        "False": {
4516
                            "expected_value": false,
4517
                            "trial_ids": [
4518
                                "NCT00002631"
4519
                            ],
4520
                            "truth_value": "unknown"
4521
                        }
4522
                    }
4523
                }
4524
            }
4525
        },
4526
        "growth factor administration": {
4527
            "criterion": "growth factor administration",
4528
            "requirements": {
4529
                "presence": {
4530
                    "requirement_type": "presence",
4531
                    "groups": {
4532
                        "False": {
4533
                            "expected_value": false,
4534
                            "trial_ids": [
4535
                                "NCT00002631"
4536
                            ],
4537
                            "truth_value": "unknown"
4538
                        }
4539
                    }
4540
                }
4541
            }
4542
        },
4543
        "chest irradiation": {
4544
            "criterion": "chest irradiation",
4545
            "requirements": {
4546
                "prior treatment": {
4547
                    "requirement_type": "prior treatment",
4548
                    "groups": {
4549
                        "False": {
4550
                            "expected_value": false,
4551
                            "trial_ids": [
4552
                                "NCT00002631"
4553
                            ],
4554
                            "truth_value": "unknown"
4555
                        }
4556
                    }
4557
                }
4558
            }
4559
        },
4560
        "resection": {
4561
            "criterion": "resection",
4562
            "requirements": {
4563
                "prior treatment": {
4564
                    "requirement_type": "prior treatment",
4565
                    "groups": {
4566
                        "False": {
4567
                            "expected_value": false,
4568
                            "trial_ids": [
4569
                                "NCT00002631"
4570
                            ],
4571
                            "truth_value": "unknown"
4572
                        }
4573
                    }
4574
                }
4575
            }
4576
        }
4577
    }
4578
}