{
    "info": {
        "nct_id": "NCT03034096",
        "official_title": "General Anesthetics in CAncer REsection Surgery (GA-CARES) Trial: Pragmatic Randomized Trial of Propofol vs Volatile Inhalational Anesthesia",
        "inclusion_criteria": "* Patients with known or suspected cancer and scheduled to undergo any of the following oncologic surgical procedures:\n\n  * Lobectomy or pneumonectomy\n  * Esophagectomy\n  * Radical (total) cystectomy\n  * Pancreatectomy\n  * Partial hepatectomy\n  * Hyperthermic intraperitoneal chemotherapy (HIPEC)\n  * Gastrectomy (subtotal or total)\n  * Cholecystectomy or bile duct resection\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "* Age less than 18 years\n* American Society of Anesthesiologist Class 5\n* Projected life expectancy less than 30 days\n* Known or suspected hypersensitivity to either propofol, e.g. egg or soy allergy, or volatile general anesthetic agents\n* Known or suspected history of malignant hyperthermia",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* Patients with known or suspected cancer and scheduled to undergo any of the following oncologic surgical procedures:",
                "criterions": [
                    {
                        "exact_snippets": [
                            "known or suspected cancer"
                        ],
                        "criterion": "cancer",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "scheduled to undergo any of the following oncologic surgical procedures"
                        ],
                        "criterion": "oncologic surgical procedures",
                        "requirement_type": "scheduled",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "known or suspected cancer"
                        ],
                        "criterion": "cancer",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "scheduled to undergo any of the following oncologic surgical procedures"
                        ],
                        "criterion": "oncologic surgical procedures",
                        "requirement_type": "scheduled",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Lobectomy or pneumonectomy",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Lobectomy"
                        ],
                        "criterion": "lobectomy",
                        "requirement_type": "history",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "pneumonectomy"
                        ],
                        "criterion": "pneumonectomy",
                        "requirement_type": "history",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": [
                            "Lobectomy"
                        ],
                        "criterion": "lobectomy",
                        "requirement_type": "history",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "pneumonectomy"
                        ],
                        "criterion": "pneumonectomy",
                        "requirement_type": "history",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Esophagectomy",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Esophagectomy"
                        ],
                        "criterion": "esophagectomy",
                        "requirement_type": "procedure",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "Esophagectomy"
                        ],
                        "criterion": "esophagectomy",
                        "requirement_type": "procedure",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Radical (total) cystectomy",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Radical (total) cystectomy"
                        ],
                        "criterion": "cystectomy",
                        "requirement_type": "type",
                        "expected_value": "radical (total)"
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "Radical (total) cystectomy"
                        ],
                        "criterion": "cystectomy",
                        "requirement_type": "type",
                        "expected_value": "radical (total)"
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Pancreatectomy",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Pancreatectomy"
                        ],
                        "criterion": "pancreatectomy",
                        "requirement_type": "history",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "Pancreatectomy"
                        ],
                        "criterion": "pancreatectomy",
                        "requirement_type": "history",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Partial hepatectomy",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Partial hepatectomy"
                        ],
                        "criterion": "hepatectomy",
                        "requirement_type": "type",
                        "expected_value": "partial"
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "Partial hepatectomy"
                        ],
                        "criterion": "hepatectomy",
                        "requirement_type": "type",
                        "expected_value": "partial"
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Hyperthermic intraperitoneal chemotherapy (HIPEC)",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Hyperthermic intraperitoneal chemotherapy (HIPEC)"
                        ],
                        "criterion": "Hyperthermic intraperitoneal chemotherapy",
                        "requirement_type": "N/A",
                        "expected_value": "HIPEC"
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "Hyperthermic intraperitoneal chemotherapy (HIPEC)"
                        ],
                        "criterion": "Hyperthermic intraperitoneal chemotherapy",
                        "requirement_type": "N/A",
                        "expected_value": "HIPEC"
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Gastrectomy (subtotal or total)",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Gastrectomy (subtotal or total)"
                        ],
                        "criterion": "gastrectomy",
                        "requirement_type": "type",
                        "expected_value": [
                            "subtotal",
                            "total"
                        ]
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "Gastrectomy (subtotal or total)"
                        ],
                        "criterion": "gastrectomy",
                        "requirement_type": "type",
                        "expected_value": [
                            "subtotal",
                            "total"
                        ]
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Cholecystectomy or bile duct resection",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Cholecystectomy"
                        ],
                        "criterion": "cholecystectomy",
                        "requirement_type": "history",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "bile duct resection"
                        ],
                        "criterion": "bile duct resection",
                        "requirement_type": "history",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": [
                            "Cholecystectomy"
                        ],
                        "criterion": "cholecystectomy",
                        "requirement_type": "history",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "bile duct resection"
                        ],
                        "criterion": "bile duct resection",
                        "requirement_type": "history",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Healthy volunteers allowed"
                        ],
                        "criterion": "healthy volunteers",
                        "requirement_type": "participation",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "Healthy volunteers allowed"
                        ],
                        "criterion": "healthy volunteers",
                        "requirement_type": "participation",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 18 Years",
                "criterions": [
                    {
                        "exact_snippets": [
                            "minimum age of 18 Years"
                        ],
                        "criterion": "age",
                        "requirement_type": "minimum",
                        "expected_value": {
                            "operator": ">=",
                            "value": 18
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "minimum age of 18 Years"
                        ],
                        "criterion": "age",
                        "requirement_type": "minimum",
                        "expected_value": {
                            "operator": ">=",
                            "value": 18
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "* Age less than 18 years",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Age less than 18 years"
                        ],
                        "criterion": "age",
                        "requirement_type": "range",
                        "expected_value": {
                            "comparisons": [
                                {
                                    "operator": "<",
                                    "value": 18
                                }
                            ]
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "Age less than 18 years"
                    ],
                    "criterion": "age",
                    "requirement_type": "range",
                    "expected_value": {
                        "comparisons": [
                            {
                                "operator": "<",
                                "value": 18
                            }
                        ]
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* American Society of Anesthesiologist Class 5",
                "criterions": [
                    {
                        "exact_snippets": [
                            "American Society of Anesthesiologist Class 5"
                        ],
                        "criterion": "American Society of Anesthesiologist Class",
                        "requirement_type": "classification",
                        "expected_value": "5"
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "American Society of Anesthesiologist Class 5"
                    ],
                    "criterion": "American Society of Anesthesiologist Class",
                    "requirement_type": "classification",
                    "expected_value": "5"
                }
            }
        },
        {
            "identified_line": {
                "line": "* Projected life expectancy less than 30 days",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Projected life expectancy less than 30 days"
                        ],
                        "criterion": "life expectancy",
                        "requirement_type": "quantity",
                        "expected_value": {
                            "operator": "<",
                            "value": 30
                        }
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "Projected life expectancy less than 30 days"
                    ],
                    "criterion": "life expectancy",
                    "requirement_type": "quantity",
                    "expected_value": {
                        "operator": "<",
                        "value": 30
                    }
                }
            }
        },
        {
            "identified_line": {
                "line": "* Known or suspected hypersensitivity to either propofol, e.g. egg or soy allergy, or volatile general anesthetic agents",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Known or suspected hypersensitivity to either propofol"
                        ],
                        "criterion": "hypersensitivity to propofol",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "egg or soy allergy"
                        ],
                        "criterion": "egg or soy allergy",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "hypersensitivity to",
                            "volatile general anesthetic agents"
                        ],
                        "criterion": "hypersensitivity to volatile general anesthetic agents",
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "or_criteria": [
                            {
                                "exact_snippets": [
                                    "Known or suspected hypersensitivity to either propofol"
                                ],
                                "criterion": "hypersensitivity to propofol",
                                "requirement_type": "presence",
                                "expected_value": true
                            },
                            {
                                "exact_snippets": [
                                    "egg or soy allergy"
                                ],
                                "criterion": "egg or soy allergy",
                                "requirement_type": "presence",
                                "expected_value": true
                            }
                        ]
                    },
                    {
                        "exact_snippets": [
                            "hypersensitivity to",
                            "volatile general anesthetic agents"
                        ],
                        "criterion": "hypersensitivity to volatile general anesthetic agents",
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Known or suspected history of malignant hyperthermia",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Known or suspected history of malignant hyperthermia"
                        ],
                        "criterion": "malignant hyperthermia",
                        "requirement_type": "history",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "Known or suspected history of malignant hyperthermia"
                    ],
                    "criterion": "malignant hyperthermia",
                    "requirement_type": "history",
                    "expected_value": true
                }
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}