{
    "info": {
        "nct_id": "NCT02321202",
        "official_title": "Omega-3 Fatty Acid-Based Parenteral Nutrition Improves Postoperative Recovery for Cirrhotic Patients With Liver Cancer",
        "inclusion_criteria": "* The cirrhotic malnourished patients who were diagnosed as liver cancer preoperatively and underwent hepatectomy were consecutively enrolled.\nHealthy volunteers allowed\nMust have minimum age of 18 Years\nMust have maximum age of 75 Years",
        "exclusion_criteria": "* Contraindication for hepatectomy, including gastrointestinal hemorrhage, severe hemorrhagic disorders, explicit acute nonspecific infectious lesion, overt ascites, Child-Pugh Score C, indocyanine green retention rate at 15min (ICGR15)>30%(12), serum hepatitis B virus (HBV)-DNA>126 copies/ml and serum alanine aminotransferase (ALT) > 2×ULN, serum triglycerides>2.0 mmol/L, circulatory shock, stroke, acute myocardial infarction, renal failure, coma of unknown cause\n* Pregnancy\n* Age of<18y or>75y\n* Performed intraoperative ablation\n* Unresectable tumor during operation\n* Allergic reactions against fish or egg proteins",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* The cirrhotic malnourished patients who were diagnosed as liver cancer preoperatively and underwent hepatectomy were consecutively enrolled.",
                "criterions": [
                    {
                        "exact_snippets": [
                            "cirrhotic"
                        ],
                        "criterion": "cirrhosis",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "malnourished"
                        ],
                        "criterion": "malnutrition",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "diagnosed as liver cancer"
                        ],
                        "criterion": "liver cancer",
                        "requirement_type": "diagnosis",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "underwent hepatectomy"
                        ],
                        "criterion": "hepatectomy",
                        "requirement_type": "history",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": [
                                    "cirrhotic"
                                ],
                                "criterion": "cirrhosis",
                                "requirement_type": "presence",
                                "expected_value": true
                            },
                            {
                                "exact_snippets": [
                                    "malnourished"
                                ],
                                "criterion": "malnutrition",
                                "requirement_type": "presence",
                                "expected_value": true
                            }
                        ]
                    },
                    {
                        "exact_snippets": [
                            "diagnosed as liver cancer"
                        ],
                        "criterion": "liver cancer",
                        "requirement_type": "diagnosis",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "underwent hepatectomy"
                        ],
                        "criterion": "hepatectomy",
                        "requirement_type": "history",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Healthy volunteers allowed"
                        ],
                        "criterion": "healthy volunteers",
                        "requirement_type": "participation",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "Healthy volunteers allowed"
                        ],
                        "criterion": "healthy volunteers",
                        "requirement_type": "participation",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 18 Years",
                "criterions": [
                    {
                        "exact_snippets": [
                            "minimum age of 18 Years"
                        ],
                        "criterion": "age",
                        "requirement_type": "minimum",
                        "expected_value": {
                            "operator": ">=",
                            "value": 18
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "minimum age of 18 Years"
                        ],
                        "criterion": "age",
                        "requirement_type": "minimum",
                        "expected_value": {
                            "operator": ">=",
                            "value": 18
                        }
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have maximum age of 75 Years",
                "criterions": [
                    {
                        "exact_snippets": [
                            "maximum age of 75 Years"
                        ],
                        "criterion": "age",
                        "requirement_type": "maximum",
                        "expected_value": {
                            "operator": "<=",
                            "value": 75
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "maximum age of 75 Years"
                        ],
                        "criterion": "age",
                        "requirement_type": "maximum",
                        "expected_value": {
                            "operator": "<=",
                            "value": 75
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [
        {
            "identified_line": {
                "line": "* Contraindication for hepatectomy, including gastrointestinal hemorrhage, severe hemorrhagic disorders, explicit acute nonspecific infectious lesion, overt ascites, Child-Pugh Score C, indocyanine green retention rate at 15min (ICGR15)>30%(12), serum hepatitis B virus (HBV)-DNA>126 copies/ml and serum alanine aminotransferase (ALT) > 2×ULN, serum triglycerides>2.0 mmol/L, circulatory shock, stroke, acute myocardial infarction, renal failure, coma of unknown cause",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Contraindication for hepatectomy"
                        ],
                        "criterion": "hepatectomy",
                        "requirement_type": "contraindication",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "gastrointestinal hemorrhage"
                        ],
                        "criterion": "gastrointestinal hemorrhage",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "severe hemorrhagic disorders"
                        ],
                        "criterion": "hemorrhagic disorders",
                        "requirement_type": "severity",
                        "expected_value": "severe"
                    },
                    {
                        "exact_snippets": [
                            "explicit acute nonspecific infectious lesion"
                        ],
                        "criterion": "acute nonspecific infectious lesion",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "overt ascites"
                        ],
                        "criterion": "ascites",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "Child-Pugh Score C"
                        ],
                        "criterion": "Child-Pugh Score",
                        "requirement_type": "value",
                        "expected_value": "C"
                    },
                    {
                        "exact_snippets": [
                            "indocyanine green retention rate at 15min (ICGR15)>30%"
                        ],
                        "criterion": "indocyanine green retention rate at 15min (ICGR15)",
                        "requirement_type": "value",
                        "expected_value": {
                            "operator": ">",
                            "value": 30
                        }
                    },
                    {
                        "exact_snippets": [
                            "serum hepatitis B virus (HBV)-DNA>126 copies/ml"
                        ],
                        "criterion": "serum hepatitis B virus (HBV)-DNA",
                        "requirement_type": "value",
                        "expected_value": {
                            "operator": ">",
                            "value": 126
                        }
                    },
                    {
                        "exact_snippets": [
                            "serum alanine aminotransferase (ALT) > 2×ULN"
                        ],
                        "criterion": "serum alanine aminotransferase (ALT)",
                        "requirement_type": "value",
                        "expected_value": "> 2×ULN"
                    },
                    {
                        "exact_snippets": [
                            "serum triglycerides>2.0 mmol/L"
                        ],
                        "criterion": "serum triglycerides",
                        "requirement_type": "value",
                        "expected_value": {
                            "operator": ">",
                            "value": 2.0
                        }
                    },
                    {
                        "exact_snippets": [
                            "circulatory shock"
                        ],
                        "criterion": "circulatory shock",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "stroke"
                        ],
                        "criterion": "stroke",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "acute myocardial infarction"
                        ],
                        "criterion": "myocardial infarction",
                        "requirement_type": "acuteness",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "renal failure"
                        ],
                        "criterion": "renal failure",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "coma of unknown cause"
                        ],
                        "criterion": "coma of unknown cause",
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "and_criteria": [
                            {
                                "exact_snippets": [
                                    "Contraindication for hepatectomy"
                                ],
                                "criterion": "hepatectomy",
                                "requirement_type": "contraindication",
                                "expected_value": true
                            },
                            {
                                "or_criteria": [
                                    {
                                        "exact_snippets": [
                                            "gastrointestinal hemorrhage"
                                        ],
                                        "criterion": "gastrointestinal hemorrhage",
                                        "requirement_type": "presence",
                                        "expected_value": true
                                    },
                                    {
                                        "exact_snippets": [
                                            "severe hemorrhagic disorders"
                                        ],
                                        "criterion": "hemorrhagic disorders",
                                        "requirement_type": "severity",
                                        "expected_value": "severe"
                                    },
                                    {
                                        "exact_snippets": [
                                            "explicit acute nonspecific infectious lesion"
                                        ],
                                        "criterion": "acute nonspecific infectious lesion",
                                        "requirement_type": "presence",
                                        "expected_value": true
                                    },
                                    {
                                        "exact_snippets": [
                                            "overt ascites"
                                        ],
                                        "criterion": "ascites",
                                        "requirement_type": "presence",
                                        "expected_value": true
                                    },
                                    {
                                        "exact_snippets": [
                                            "Child-Pugh Score C"
                                        ],
                                        "criterion": "Child-Pugh Score",
                                        "requirement_type": "value",
                                        "expected_value": "C"
                                    },
                                    {
                                        "exact_snippets": [
                                            "indocyanine green retention rate at 15min (ICGR15)>30%"
                                        ],
                                        "criterion": "indocyanine green retention rate at 15min (ICGR15)",
                                        "requirement_type": "value",
                                        "expected_value": {
                                            "operator": ">",
                                            "value": 30
                                        }
                                    },
                                    {
                                        "exact_snippets": [
                                            "serum hepatitis B virus (HBV)-DNA>126 copies/ml"
                                        ],
                                        "criterion": "serum hepatitis B virus (HBV)-DNA",
                                        "requirement_type": "value",
                                        "expected_value": {
                                            "operator": ">",
                                            "value": 126
                                        }
                                    },
                                    {
                                        "exact_snippets": [
                                            "serum alanine aminotransferase (ALT) > 2×ULN"
                                        ],
                                        "criterion": "serum alanine aminotransferase (ALT)",
                                        "requirement_type": "value",
                                        "expected_value": "> 2×ULN"
                                    },
                                    {
                                        "exact_snippets": [
                                            "serum triglycerides>2.0 mmol/L"
                                        ],
                                        "criterion": "serum triglycerides",
                                        "requirement_type": "value",
                                        "expected_value": {
                                            "operator": ">",
                                            "value": 2.0
                                        }
                                    },
                                    {
                                        "exact_snippets": [
                                            "circulatory shock"
                                        ],
                                        "criterion": "circulatory shock",
                                        "requirement_type": "presence",
                                        "expected_value": true
                                    },
                                    {
                                        "exact_snippets": [
                                            "stroke"
                                        ],
                                        "criterion": "stroke",
                                        "requirement_type": "presence",
                                        "expected_value": true
                                    },
                                    {
                                        "exact_snippets": [
                                            "acute myocardial infarction"
                                        ],
                                        "criterion": "myocardial infarction",
                                        "requirement_type": "acuteness",
                                        "expected_value": true
                                    },
                                    {
                                        "exact_snippets": [
                                            "renal failure"
                                        ],
                                        "criterion": "renal failure",
                                        "requirement_type": "presence",
                                        "expected_value": true
                                    },
                                    {
                                        "exact_snippets": [
                                            "coma of unknown cause"
                                        ],
                                        "criterion": "coma of unknown cause",
                                        "requirement_type": "presence",
                                        "expected_value": true
                                    }
                                ]
                            }
                        ]
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Pregnancy",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Pregnancy"
                        ],
                        "criterion": "pregnancy",
                        "requirement_type": "presence",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "Pregnancy"
                    ],
                    "criterion": "pregnancy",
                    "requirement_type": "presence",
                    "expected_value": true
                }
            }
        },
        {
            "identified_line": {
                "line": "* Performed intraoperative ablation",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Performed intraoperative ablation"
                        ],
                        "criterion": "intraoperative ablation",
                        "requirement_type": "performance",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "Performed intraoperative ablation"
                    ],
                    "criterion": "intraoperative ablation",
                    "requirement_type": "performance",
                    "expected_value": true
                }
            }
        },
        {
            "identified_line": {
                "line": "* Unresectable tumor during operation",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Unresectable tumor"
                        ],
                        "criterion": "tumor",
                        "requirement_type": "resectability",
                        "expected_value": false
                    }
                ]
            },
            "logical_structure": {
                "not_criteria": {
                    "exact_snippets": [
                        "Unresectable tumor"
                    ],
                    "criterion": "tumor",
                    "requirement_type": "resectability",
                    "expected_value": false
                }
            }
        },
        {
            "identified_line": {
                "line": "* Allergic reactions against fish or egg proteins",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Allergic reactions against fish"
                        ],
                        "criterion": "fish protein",
                        "requirement_type": "allergic reaction",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "Allergic reactions against",
                            "egg proteins"
                        ],
                        "criterion": "egg protein",
                        "requirement_type": "allergic reaction",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": [
                            "Allergic reactions against fish"
                        ],
                        "criterion": "fish protein",
                        "requirement_type": "allergic reaction",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "Allergic reactions against",
                            "egg proteins"
                        ],
                        "criterion": "egg protein",
                        "requirement_type": "allergic reaction",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "* Age of<18y or>75y",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Age of<18y"
                        ],
                        "criterion": "age",
                        "requirement_type": "range",
                        "expected_value": {
                            "comparisons": [
                                {
                                    "operator": "<",
                                    "value": 18
                                }
                            ]
                        }
                    },
                    {
                        "exact_snippets": [
                            "Age of>75y"
                        ],
                        "criterion": "age",
                        "requirement_type": "range",
                        "expected_value": {
                            "comparisons": [
                                {
                                    "operator": ">",
                                    "value": 75
                                }
                            ]
                        }
                    }
                ]
            },
            "logical_structure": {
                "or_criteria": [
                    {
                        "exact_snippets": [
                            "Age of<18y"
                        ],
                        "criterion": "age",
                        "requirement_type": "range",
                        "expected_value": {
                            "comparisons": [
                                {
                                    "operator": "<",
                                    "value": 18
                                }
                            ]
                        }
                    },
                    {
                        "exact_snippets": [
                            "Age of>75y"
                        ],
                        "criterion": "age",
                        "requirement_type": "range",
                        "expected_value": {
                            "comparisons": [
                                {
                                    "operator": ">",
                                    "value": 75
                                }
                            ]
                        }
                    }
                ]
            }
        }
    ],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}