{
    "info": {
        "nct_id": "NCT02222272",
        "official_title": "Effect of Prior Therapy With Nilotinib or Dasatinib on the Outcome After Allogeneic Stem Cell Transplantation for Patients With Chronic Myeloid Leukaemia",
        "inclusion_criteria": "* All adult patients with chronic myeloid leukaemia in any phase (chronic, accelerated or blastic) who undergo allogeneic stem cell transplantation between 01/01/2010 and 30/09/2013 and have been previously treated with Nilotinib or Dasatinib, regardless of their response to these drugs.\nHealthy volunteers allowed\nMust have minimum age of 18 Years",
        "exclusion_criteria": "",
        "miscellaneous_criteria": ""
    },
    "inclusion_lines": [
        {
            "identified_line": {
                "line": "* All adult patients with chronic myeloid leukaemia in any phase (chronic, accelerated or blastic) who undergo allogeneic stem cell transplantation between 01/01/2010 and 30/09/2013 and have been previously treated with Nilotinib or Dasatinib, regardless of their response to these drugs.",
                "criterions": [
                    {
                        "exact_snippets": [
                            "adult patients"
                        ],
                        "criterion": "age",
                        "requirement_type": "category",
                        "expected_value": "adult"
                    },
                    {
                        "exact_snippets": [
                            "chronic myeloid leukaemia"
                        ],
                        "criterion": "chronic myeloid leukaemia",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "chronic myeloid leukaemia",
                            "in any phase (chronic, accelerated or blastic)"
                        ],
                        "criterion": "chronic myeloid leukaemia phase",
                        "requirement_type": "category",
                        "expected_value": [
                            "chronic",
                            "accelerated",
                            "blastic"
                        ]
                    },
                    {
                        "exact_snippets": [
                            "undergo allogeneic stem cell transplantation"
                        ],
                        "criterion": "allogeneic stem cell transplantation",
                        "requirement_type": "procedure",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "between 01/01/2010 and 30/09/2013"
                        ],
                        "criterion": "transplantation date",
                        "requirement_type": "range",
                        "expected_value": {
                            "comparisons": [
                                {
                                    "operator": ">=",
                                    "value": 20100101
                                },
                                {
                                    "operator": "<=",
                                    "value": 20130930
                                }
                            ]
                        }
                    },
                    {
                        "exact_snippets": [
                            "previously treated with Nilotinib or Dasatinib"
                        ],
                        "criterion": "treatment",
                        "requirement_type": "previous",
                        "expected_value": [
                            "Nilotinib",
                            "Dasatinib"
                        ]
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "adult patients"
                        ],
                        "criterion": "age",
                        "requirement_type": "category",
                        "expected_value": "adult"
                    },
                    {
                        "exact_snippets": [
                            "chronic myeloid leukaemia"
                        ],
                        "criterion": "chronic myeloid leukaemia",
                        "requirement_type": "presence",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "chronic myeloid leukaemia",
                            "in any phase (chronic, accelerated or blastic)"
                        ],
                        "criterion": "chronic myeloid leukaemia phase",
                        "requirement_type": "category",
                        "expected_value": [
                            "chronic",
                            "accelerated",
                            "blastic"
                        ]
                    },
                    {
                        "exact_snippets": [
                            "undergo allogeneic stem cell transplantation"
                        ],
                        "criterion": "allogeneic stem cell transplantation",
                        "requirement_type": "procedure",
                        "expected_value": true
                    },
                    {
                        "exact_snippets": [
                            "between 01/01/2010 and 30/09/2013"
                        ],
                        "criterion": "transplantation date",
                        "requirement_type": "range",
                        "expected_value": {
                            "comparisons": [
                                {
                                    "operator": ">=",
                                    "value": 20100101
                                },
                                {
                                    "operator": "<=",
                                    "value": 20130930
                                }
                            ]
                        }
                    },
                    {
                        "exact_snippets": [
                            "previously treated with Nilotinib or Dasatinib"
                        ],
                        "criterion": "treatment",
                        "requirement_type": "previous",
                        "expected_value": [
                            "Nilotinib",
                            "Dasatinib"
                        ]
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Healthy volunteers allowed",
                "criterions": [
                    {
                        "exact_snippets": [
                            "Healthy volunteers allowed"
                        ],
                        "criterion": "healthy volunteers",
                        "requirement_type": "participation",
                        "expected_value": true
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "Healthy volunteers allowed"
                        ],
                        "criterion": "healthy volunteers",
                        "requirement_type": "participation",
                        "expected_value": true
                    }
                ]
            }
        },
        {
            "identified_line": {
                "line": "Must have minimum age of 18 Years",
                "criterions": [
                    {
                        "exact_snippets": [
                            "minimum age of 18 Years"
                        ],
                        "criterion": "age",
                        "requirement_type": "minimum",
                        "expected_value": {
                            "operator": ">=",
                            "value": 18
                        }
                    }
                ]
            },
            "logical_structure": {
                "and_criteria": [
                    {
                        "exact_snippets": [
                            "minimum age of 18 Years"
                        ],
                        "criterion": "age",
                        "requirement_type": "minimum",
                        "expected_value": {
                            "operator": ">=",
                            "value": 18
                        }
                    }
                ]
            }
        }
    ],
    "exclusion_lines": [],
    "miscellaneous_lines": [],
    "failed_inclusion": [],
    "failed_exclusion": [],
    "failed_miscellaneous": []
}